Acetadote and international normalised ratio increased Patient Reports February 10, 2010

Acetadote Side Effects Report #4786717-8
Acetadote side effect was reported by a Physician from UNITED STATES on Oct 03, 2005. Male patient, 31 years of age, weighting 160.0 lb, was diagnosed with overdose and was treated with Acetadote. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, international normalised ratio increased, mental status changes. Acetadote dosage: 150MG/KG, 50 MG/KG, 100 MG/KG 15 MINS,4 + 16 HRS IV DRIP. Patient recovered.

Acetadote Side Effects Report #5385105-3
Acetadote side effect was reported by a Physician from UNITED STATES on July 06, 2007. Female patient, 48 years of age, weighting 146.0 lb, was treated with Acetadote. After drug was administered, patient experienced the following side effects: hepatic encephalopathy, international normalised ratio increased, liver function test abnormal. Acetadote dosage: 150 MG/KG, 50 MG/KG, 100 MG/K OVER 1, 4, 16 HRS IV DRIP. During the same period patient was treated with LOPRESSOR, BICARBONATE, GOLYTELY, ACTIVATED CHARCOAL. Patient died.

Acetadote Side Effects Report #4801848-1
Acetadote side effect was reported by a Physician from UNITED STATES on Sept 30, 2005. Male patient, 31 years of age, weighting 160.0 lb, was treated with Acetadote. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, hepatotoxicity, international normalised ratio increased, liver transplant . Acetadote dosage: 300 MG/KG, IV. During the same period patient was treated with ACETYLCYSTEINE. Patient was hospitalized. Patient recovered.

Acetadote Side Effects Report #4816583-3
Acetadote side effect was reported by a Physician from UNITED STATES on Oct 19, 2005. Male patient, 31 years of age, weighting 160.0 lb, was treated with Acetadote. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, carbon dioxide decreased, hepatic function abnormal, international normalised ratio increased, liver transplant . Acetadote dosage: 300 MG/KG IV. During the same period patient was treated with ACETYLCYSTEINE, ACTIVATED CHARCOAL. Patient was hospitalized. Patient recovered.