Adagen and anaemia haemolytic autoimmune Patient Reports February 10, 2010

Adagen Side Effects Report #5136007-9
Adagen side effect was reported by a Physician from ITALY on Oct 11, 2006. Male patient was diagnosed with combined immunodeficiency and was treated with Adagen. After drug was administered, patient experienced the following side effects: anaemia haemolytic autoimmune, epilepsy . Adagen dosage: unknown. During the same period patient was treated with AMPHOTERICIN B, IMMUNOGLOBULINS, ACYCLOVIR, COTRIMOXAZOLE, PHENOBARBITAL, GANCICLOVIR. Patient was hospitalized. Patient recovered.

Adagen Side Effects Report #5189835-8
Adagen side effect was reported by a Physician from FRANCE on Dec 05, 2006. Male patient was diagnosed with combined immunodeficiency and was treated with Adagen. After drug was administered, patient experienced the following side effects: anaemia haemolytic autoimmune, epilepsy . Adagen dosage: unknown. During the same period patient was treated with AMPHOTERICIN B, IMMUNOGLOBULINS, ACYCLOVIR, COTRIM D, PHENOBARBITAL, GANCICLOVIR. Patient was hospitalized. Patient recovered.

Adagen Side Effects Report #5574101-9
Adagen side effect was reported by a Physician from FRANCE on Dec 12, 2007. Male patient, weighting 22.05 lb, was diagnosed with combined immunodeficiency and was treated with Adagen. After drug was administered, patient experienced the following side effects: anaemia haemolytic autoimmune, epilepsy , malaise. Adagen dosage: unknown. During the same period patient was treated with AMPHOTERICIN B, IMMUNOGLOBULINS, ACYCLOVIR, COTRIM. Patient was hospitalized. Patient recovered.

Adagen Side Effects Report #6081501-X
Adagen side effect was reported by a Consumer or non-health professional from UNITED STATES on Jan 29, 2009. Female patient was diagnosed with combined immunodeficiency and was treated with Adagen. After drug was administered, patient experienced the following side effects: anaemia haemolytic autoimmune, autoimmune thrombocytopenia, developmental delay, failure to thrive, histiocytosis haematophagic, hypertension, hypoacusis, neutropenia, renal vein thrombosis. Adagen dosage: unknown. During the same period patient was treated with IMMUNOGLOBULINS, ACYCLOVIR, ITRACONAZOLE, AMPICILLIN. Patient was hospitalized. Patient recovered.


Adagen Side Effects Report #6093673-1
Adagen side effect was reported by a Physician from FRANCE on Feb 13, 2009. Male patient was diagnosed with combined immunodeficiency and was treated with Adagen. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, anaemia haemolytic autoimmune, aspartate aminotransferase increased, blood urea increased, disseminated intravascular coagulation. Adagen dosage: unknown. During the same period patient was treated with RIFAMPICIN, ISONIAZID, ETHAMBUTOL, BACTRIM, FLUCONAZOLE, CEFTAZIDIME, CLARITHROMYCIN. Patient was hospitalized. Patient died on 12/12/2008.

Adagen Side Effects Report #6112008-9
Adagen side effect was reported by a Consumer or non-health professional from ITALY on Feb 25, 2009. Male patient, weighting 22.05 lb, was diagnosed with combined immunodeficiency and was treated with Adagen. After drug was administered, patient experienced the following side effects: anaemia haemolytic autoimmune, coombs test positive, epilepsy . Adagen dosage: unknown. During the same period patient was treated with AMPHOTERICIN B , IMMUNOGLOBULINS, ACYCLOVIR, COTRIMOXAZOLE. Patient was hospitalized and became disabled. Patient recovered.

Adagen Side Effects Report #4985744-5
Adagen side effect was reported by a Physician from FRANCE on Apr 10, 2006. Female patient was diagnosed with combined immunodeficiency and was treated with Adagen. After drug was administered, patient experienced the following side effects: anaemia haemolytic autoimmune. Adagen dosage: unknown. Patient recovered.