Aldurazyme and anaphylactic reaction 
Aldurazyme and anaphylactic reaction Patient Reports February 10, 2010
Aldurazyme Side Effects Report #5694209-7
Aldurazyme side effect was reported by a Physician from ECUADOR on Mar 17, 2008. Female patient, child 7 years of age, weighting 31.97 lb, was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: anaphylactic reaction, hepatomegaly, hypertension, infusion related reaction, irritability, pneumonia
, transaminases increased. Aldurazyme dosage: 0.58 MG/KG, 1X/W, INTRAVENOUS. During the same period patient was treated with ENALAPRIL MALEATE AND HYDROCHLOROTHIAZIDE, FUROSEMIDE. Patient was hospitalized. Patient recovered.Aldurazyme Side Effects Report #5985306-7
Aldurazyme side effect was reported by a Consumer or non-health professional from ECUADOR on Nov 19, 2008. Female patient, child 7 years of age, weighting 31.97 lb, was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: anaphylactic reaction, hepatomegaly, hypertension, infusion related reaction, irritability, pneumonia
, transaminases increased. Aldurazyme dosage: 0.58 MG/KG, 1X/W, INTRAVENOUS. During the same period patient was treated with ENALAPRIL MALEATE AND HYDROCHLOROTHIAZIDE, FUROSEMIDE. Patient died on 11/19/2008.Aldurazyme Side Effects Report #6010152-8
Aldurazyme side effect was reported by a Physician from ECUADOR on Dec 02, 2008. Female patient, child 7 years of age, weighting 31.97 lb, was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: acute respiratory failure, anaphylactic reaction, blood ph decreased, blood urea increased, cough, cyanosis, haematocrit increased, haemoglobin increased, hepatomegaly. Aldurazyme dosage: 0.58 MG/KG, 1X/W, INTRAVENOUS. During the same period patient was treated with ENALAPRIL MALEATE AND HYDROCHLOROTHIAZIDE, FUROSEMIDE. Patient died on 11/19/2008.
Aldurazyme Side Effects Report #5551066-7
Aldurazyme side effect was reported by a Physician from ECUADOR on Nov 23, 2007. Female patient, child 6 years of age, weighting 31.97 lb, was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: anaphylactic reaction, blood pressure increased, pharyngitis, tonsillitis, upper respiratory tract infection. Aldurazyme dosage: 0.58 MG/KG QWK IV. During the same period patient was treated with ENALAPRIL, FUROSEMIDE, CETIRIZINE, ACETAMINOPHEN. Patient recovered.
Aldurazyme Side Effects Report #5584612-8
Aldurazyme side effect was reported by a Physician from ECUADOR on Dec 20, 2007. Female patient, child 6 years of age, weighting 31.97 lb, was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: anaphylactic reaction, blood pressure increased, pharyngitis, respiratory rate increased, tonsillitis, upper respiratory tract infection. Aldurazyme dosage: 0.58 MG/KG, QW, INTRAVENOUS. During the same period patient was treated with ENALAPRIL MALEATE, FUROSEMIDE, CETIRIZINE, ACETAMINOPHEN. Patient recovered.
Aldurazyme Side Effects Report #5600997-8
Aldurazyme side effect was reported by a Physician from ECUADOR on Jan 04, 2008. Female patient, child 6 years of age, weighting 31.97 lb, was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: anaphylactic reaction, heart rate increased, hypertension, irritability, oxygen saturation decreased, transaminases increased. Aldurazyme dosage: 0.58 MG/KG, QW, INTRAVENOUS. During the same period patient was treated with ENAPRIL, FUROSEMIDE. Patient recovered.
Aldurazyme Side Effects Report #5632954-X
Aldurazyme side effect was reported by a Physician from ECUADOR on Jan 31, 2008. Female patient, child 6 years of age, weighting 31.97 lb, was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: anaphylactic reaction, heart rate increased, hypertension, infusion related reaction, irritability, oxygen saturation decreased, respiratory rate increased, transaminases increased. Aldurazyme dosage: 0.58 MG/KG, QW,INTRAVENOUS. During the same period patient was treated with ENAPRIL, FUROSEMIDE. Patient recovered.
Aldurazyme Side Effects Report #5450879-X
Aldurazyme side effect was reported by a Health Professional from UNITED STATES on Aug 28, 2007. Female patient, 20 years of age, weighting 82.23 lb, was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: anaphylactic reaction, bronchospasm, cardio-respiratory arrest, cardiomegaly, convulsion, eyelid oedema, hypokalaemia, joint range of motion decreased, local swelling. Aldurazyme dosage: 23.2 MG QWK IV. During the same period patient was treated with CARDIZEM, MOTRIN MFR. Patient was hospitalized. Patient recovered.
Aldurazyme Side Effects Report #5592528-6
Aldurazyme side effect was reported by a Health Professional from POLAND on Dec 28, 2007. Male patient, weighting 33.07 lb, was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: anaphylactic reaction, tremor. Aldurazyme dosage: unknown. Patient was hospitalized. Patient recovered.
Aldurazyme Side Effects Report #5663327-1
Aldurazyme side effect was reported by a Health Professional from POLAND on Feb 21, 2008. Male patient, weighting 33.07 lb, was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: anaphylactic reaction, body temperature increased, heart rate increased, pallor, tremor. Aldurazyme dosage: unknown. Patient was hospitalized. Patient recovered.
Aldurazyme Side Effects Report #6032073-7
Aldurazyme side effect was reported by a Physician from TURKEY on Dec 24, 2008. Male patient, weighting 20.50 lb, was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: anaphylactic reaction, eyelid oedema, flushing, hypotension, lip oedema, respiratory arrest, respiratory distress. Aldurazyme dosage: 5.8 MG, INTRAVENOUS. Patient recovered.
Aldurazyme Side Effects Report #6050968-5
Aldurazyme side effect was reported by a Physician from TURKEY on Jan 07, 2009. Male patient, weighting 20.50 lb, was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: anaphylactic reaction, anaphylactoid reaction, flushing, hypotension, infusion related reaction, respiratory arrest, respiratory distress. Aldurazyme dosage: 5.8 MG, QW, INTRAVENOUS. Patient recovered.
Aldurazyme Side Effects Report #6125966-3
Aldurazyme side effect was reported by a Physician from TURKEY on Mar 06, 2009. Male patient, weighting 20.50 lb, was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: anaphylactic reaction, cyanosis, hypotension, infusion related reaction, respiratory arrest, respiratory distress. Aldurazyme dosage: 5.8 MG.,QW, INTRAVENOUS. Patient recovered.
Aldurazyme Side Effects Report #5616338-6
Aldurazyme side effect was reported by a Physician from ECUADOR on Jan 21, 2008. Female patient, child 6 years of age, weighting 31.97 lb, was diagnosed with mucopolysaccharidosis and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: anaphylactic reaction, heart rate increased, hypertension, irritability, oxygen saturation decreased, transaminases increased. Aldurazyme dosage: 0.58 MG/KG, QW, INTRAVENOUS. During the same period patient was treated with ENAPRIL, FUROSEMIDE. Patient recovered.