Aldurazyme and pyrexia Patient Reports February 10, 2010

Aldurazyme Side Effects Report #5390951-6
Aldurazyme side effect was reported by a Consumer or non-health professional from UNITED STATES on Feb 13, 2007. Female patient, 14 years of age, weighting 70.33 lb, was diagnosed with mucopolysaccharidosis ih and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: catheter related complication, deep vein thrombosis , peripheral coldness, pollakiuria, pyrexia, skin discolouration, urinary tract disorder. Aldurazyme dosage: 17.4 MG QWK IV. Patient recovered.

Aldurazyme Side Effects Report #5259504-4
Aldurazyme side effect was reported by a Physician from UNITED STATES on Feb 20, 2007. Female patient, child 8 years of age, weighting 50.04 lb, was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: chills, lip swelling, pyrexia, tremor, vomiting. Aldurazyme dosage: unknown. During the same period patient was treated with BENADRYL, TYLENOL, HYDROCORTISONE. Patient was hospitalized. Patient recovered.

Aldurazyme Side Effects Report #5148811-1
Aldurazyme side effect was reported by a Physician from UNITED STATES on Sept 08, 2006. Female patient, child 8 years of age, weighting 50.04 lb, was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: antibody test positive, chills, infection , infusion related reaction, lip swelling, pyrexia, tremor, vomiting. Aldurazyme dosage: unknown. During the same period patient was treated with BENADRYL, TYLENOL, HYDROCORTISONE. Patient was hospitalized. Patient recovered.

Aldurazyme Side Effects Report #4683991-3
Aldurazyme side effect was reported by a Health Professional from on Feb 15, 2005. Female patient, child 8 years of age, weighting 35.71 lb, was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: chills, ear infection , heart rate increased, oxygen saturation decreased, pyrexia, upper respiratory tract infection, wheezing. Aldurazyme dosage: 11.6 MG QWK IV. During the same period patient was treated with TYLENOL, BENADRYL. Patient recovered.


Aldurazyme Side Effects Report #5624203-3
Aldurazyme side effect was reported by a Health Professional from UNITED STATES on Jan 31, 2008. Female patient, child 7 years of age, weighting 35.27 lb, was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: bacterial infection , heart rate increased, infusion related reaction, pyrexia, respiratory arrest, respiratory distress. Aldurazyme dosage: 8.7 MG, 1X/W, INTRAVENOUS. During the same period patient was treated with BENADRYL, ALBUTEROL, MOTRIN. Patient was hospitalized. Patient recovered.

Aldurazyme Side Effects Report #5989353-0
Aldurazyme side effect was reported by a Physician from TURKEY on Nov 21, 2008. Female patient, child 7 years of age, weighting 33.07 lb, was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: anaphylactoid reaction, blood pressure diastolic decreased, chills, hypertension, pyrexia, tachycardia. Aldurazyme dosage: unknown. During the same period patient was treated with PREDNISOLONE, DIMENHYDRINATE. Patient was hospitalized. Patient recovered.

Aldurazyme Side Effects Report #6081689-0
Aldurazyme side effect was reported by a Physician from TURKEY on Jan 30, 2009. Female patient, child 7 years of age, weighting 33.07 lb, was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: anaphylactoid reaction, blood pressure diastolic decreased, chills, hypertension, infusion related reaction, pyrexia, tachycardia. Aldurazyme dosage: unknown. During the same period patient was treated with PREDNISOLONE, DIMENHYDRINATE. Patient was hospitalized. Patient recovered.

Aldurazyme Side Effects Report #6020709-6
Aldurazyme side effect was reported by a Physician from BRAZIL on Dec 05, 2008. Male patient, child 6 years of age, weighting 44.09 lb, was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: diarrhoea, infusion related reaction, pyrexia, sinusitis , tachycardia, tachypnoea. Aldurazyme dosage: unknown. Patient was hospitalized. Patient recovered.

Aldurazyme Side Effects Report #5297533-5
Aldurazyme side effect was reported by a Physician from COLOMBIA on Mar 21, 2007. Male patient, child 5 years of age, weighting 33.07 lb, was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: cyanosis, diarrhoea, dyspnoea, pyrexia, tachypnoea, tremor, vomiting. Aldurazyme dosage: 0.58 MG/KG QWK IV. During the same period patient was treated with LEVOTIROXINE, LORATADINE. Patient recovered.


Aldurazyme Side Effects Report #5390730-X
Aldurazyme side effect was reported by a Physician from UNITED STATES on Dec 20, 2005. Female patient, child 5 years of age, was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: dyspnoea, pyrexia, respiratory failure, speech disorder, viral infection , vomiting. Aldurazyme dosage: 0.6 MG/KG QWK IV. Patient was hospitalized. Patient died on 12/19/2005.

Aldurazyme Side Effects Report #4848119-5
Aldurazyme side effect was reported by a Physician from UNITED STATES on Nov 15, 2005. Female patient, child 5 years of age, was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: dyspnoea, malaise, po2 decreased, pyrexia, viral infection , vomiting. Aldurazyme dosage: unknown. Patient was hospitalized. Patient recovered.

Aldurazyme Side Effects Report #4874096-7
Aldurazyme side effect was reported by a Physician from UNITED STATES on Dec 20, 2005. Female patient, child 5 years of age, was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: dyspnoea, pyrexia, respiratory failure, speech disorder, viral infection , vomiting. Aldurazyme dosage: 0.6 MG/KG QWK IV. Patient was hospitalized. Patient died on 12/19/2005.

Aldurazyme Side Effects Report #5390768-2
Aldurazyme side effect was reported by a Physician from CROATIA (local name: Hrvatska) on Aug 12, 2003. Male patient, child 4 years of age, weighting 38.58 lb, was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: abdominal discomfort, abdominal pain upper, chills, diarrhoea, pallor, pyrexia, somnolence, tachycardia, vomiting. Aldurazyme dosage: unknown. Patient was hospitalized. Patient recovered.

Aldurazyme Side Effects Report #5390993-0
Aldurazyme side effect was reported by a Physician from UNITED STATES on Jan 23, 2006. Female patient, child 4 years of age, weighting 35.27 lb, was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: brain stem glioma, deafness, head injury, hypersensitivity, pyrexia, swelling, umbilical hernia. Aldurazyme dosage: 0.58 MG/KG QWK IV. During the same period patient was treated with BACTRIM, PULMICORT, ZYRTEC, FLONASE, ALBUTEROL. Patient recovered.


Aldurazyme Side Effects Report #5747158-X
Aldurazyme side effect was reported by a Consumer or non-health professional from UNITED STATES on May 04, 2008. Male patient, child 4 years of age, was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: aspiration, convulsion, fall , pyrexia. Aldurazyme dosage: unknown. Patient was hospitalized. Patient recovered.

Aldurazyme Side Effects Report #6128860-7
Aldurazyme side effect was reported by a Physician from UNITED STATES on Mar 09, 2009. Female patient, child 4 years of age, weighting 33.29 lb, was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: brain stem glioma, deafness, head injury, no therapeutic response, pneumonia , pyrexia, tooth extraction. Aldurazyme dosage: 0.58 MG/KG, QW, INTRAVENOUS. During the same period patient was treated with BACTRIM, PULMICORT, ZYRTEC, FLONASE, ALBUTEROL, BENADRYL, MOTRIN. Patient died on 03/08/2009.

Aldurazyme Side Effects Report #5390989-9
Aldurazyme side effect was reported by a Physician from UNITED STATES on Mar 01, 2007. Female patient, 39 years of age, was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: dyspnoea, infusion related reaction, oxygen saturation decreased, pyrexia, wheezing. Aldurazyme dosage: 0.58 MG/KG QWK IV. During the same period patient was treated with TYLENOL, CLARITIN. Patient recovered.

Aldurazyme Side Effects Report #5390755-4
Aldurazyme side effect was reported by a Physician from PORTUGAL on Sept 06, 2005. Female patient, child 3 years of age, weighting 26.46 lb, was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: angioedema, face oedema, nausea , prostration, pyrexia. Aldurazyme dosage: unknown. During the same period patient was treated with NEOSTIL. Patient was hospitalized. Patient recovered.

Aldurazyme Side Effects Report #5989355-4
Aldurazyme side effect was reported by a Physician from TURKEY on Nov 21, 2008. Male patient, child 3 years of age, weighting 35.27 lb, was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: hypersensitivity, pyrexia, restlessness. Aldurazyme dosage: unknown. Patient was hospitalized. Patient recovered.


Aldurazyme Side Effects Report #6129669-0
Aldurazyme side effect was reported by a Physician from TURKEY on Mar 06, 2009. Male patient, child 3 years of age, weighting 35.27 lb, was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: hypersensitivity, pyrexia, restlessness. Aldurazyme dosage: unknown. Patient was hospitalized. Patient recovered.

Aldurazyme Side Effects Report #4607711-3
Aldurazyme side effect was reported by a Physician from on Feb 23, 2005. Female patient, 24 years of age, weighting 116.8 lb, was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: chills, cough, hypotension, oxygen saturation decreased, pulmonary congestion, pyrexia, tachycardia. Aldurazyme dosage: 1 MG/KG QWK IV. Patient was hospitalized. Patient recovered.

Aldurazyme Side Effects Report #5892232-0
Aldurazyme side effect was reported by a Consumer or non-health professional from UNITED STATES on Aug 13, 2008. Male patient, child 2 years of age, weighting 26.46 lb, was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: anaemia haemolytic autoimmune, bone marrow transplant , ear tube insertion, infusion related reaction, neutropenia, pyrexia. Aldurazyme dosage: 5.8 MG, 1X/W, UNK. Patient recovered.

Aldurazyme Side Effects Report #5389805-0
Aldurazyme side effect was reported by a Physician from COLOMBIA on Feb 13, 2007. Female patient, weighting 33.07 lb, was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: cyanosis, irritability, oxygen saturation decreased, pyrexia, tachycardia, tachypnoea, tremor. Aldurazyme dosage: 8.7 MG, IV. During the same period patient was treated with ACETAMINOPHEN, ENALAPRIL MALEATE, AMLODIPINE, CHLORPHENIRAMINE MALEATE. Patient recovered.

Aldurazyme Side Effects Report #5594008-0
Aldurazyme side effect was reported by a Physician from FRANCE on Dec 27, 2007. Female patient, weighting 31.97 lb, was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: infusion related reaction, livedo reticularis, moaning, pyrexia. Aldurazyme dosage: unknown. Patient was hospitalized. Patient recovered.


Aldurazyme Side Effects Report #5616219-8
Aldurazyme side effect was reported by a Health Professional from AUSTRALIA on Jan 20, 2008. Male patient was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: chills, hypotension, livedo reticularis, nonspecific reaction, peripheral circulatory failure, pyrexia, supraventricular tachycardia, tachypnoea, vasoconstriction. Aldurazyme dosage: unknown. Patient recovered.

Aldurazyme Side Effects Report #4684000-2
Aldurazyme side effect was reported by a Physician from on Mar 04, 2005. Female patient was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: pyrexia, vomiting. Aldurazyme dosage: 0.58 MG/KG QWK IV. Patient recovered.

Aldurazyme Side Effects Report #5918558-X
Aldurazyme side effect was reported by a Physician from TURKEY on Sept 26, 2008. Female patient, child 7 years of age, weighting 35.27 lb, was diagnosed with mucopolysaccharidosis and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: chills, hypersensitivity, hypertension, pyrexia, tachycardia. Aldurazyme dosage: unknown. Patient was hospitalized. Patient recovered.

Aldurazyme Side Effects Report #4764191-5
Aldurazyme side effect was reported by a Health Professional from UNITED STATES on May 16, 2005. Female patient, 19 years of age, weighting 266.0 lb, was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: chills, pyrexia. Aldurazyme dosage: unknown. Patient recovered.

Aldurazyme Side Effects Report #4764192-7
Aldurazyme side effect was reported by a Consumer or non-health professional from UNITED STATES on June 06, 2005. Male patient, child 10 years of age, was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: infection , pyrexia. Aldurazyme dosage: unknown. Patient recovered.