Aprotinin and aortic thrombosis Patient Reports March 13, 2010

Aprotinin Side Effects Report #4883983-5
Aprotinin side effect was reported by a Consumer or non-health professional from UNITED STATES on Jan 09, 2006. Female patient, 69 years of age, was diagnosed with prophylaxis, disseminated intravascular coagulation, operative haemorrhage and was treated with Aprotinin. After drug was administered, patient experienced the following side effects: aortic thrombosis, atrial thrombosis, cardiac valve replacement complication, cardiogenic shock, haemorrhage, ventricular failure. Aprotinin dosage: unknown. During the same period patient was treated with PROTAMINE SULPHATE, PLATELETS, CRYOPRECIPITATES, TAMOXIFEN CITRATE, ANTIBIOTICS. Patient died.

Aprotinin Side Effects Report #4754196-2
Aprotinin side effect was reported by a Health Professional from UNITED STATES on Aug 10, 2005. Female patient, 78 years of age, was diagnosed with haemorrhage and was treated with Aprotinin. After drug was administered, patient experienced the following side effects: aortic thrombosis, cardiac arrest , haemorrhage, operative haemorrhage, post procedural haemorrhage. Aprotinin dosage: unknown. During the same period patient was treated with FENTANYL, MIDAZOLAM, PANCURONIUM, ISOFLURANE, HEPARIN. Patient died.

Aprotinin Side Effects Report #5819050-3
Aprotinin side effect was reported by a Health Professional from UNITED STATES on July 18, 2008. Female patient, 79 years of age, was diagnosed with coagulation time abnormal, bacteraemia and was treated with Aprotinin. After drug was administered, patient experienced the following side effects: aortic thrombosis, cardiac arrest , intracardiac thrombus, procedural complication, right ventricular failure. Aprotinin dosage: unknown. During the same period patient was treated with NOVOSEVEN, PROTAMINE SULPHATE, PROTAMINE SULPHATE, AMPICILLIN, GENTAMICIN. Patient died.

Aprotinin Side Effects Report #5217719-5
Aprotinin side effect was reported by a Health Professional from GERMANY on Jan 19, 2007. Female patient, 75 years of age, was diagnosed with aortic aneurysm  and was treated with Aprotinin. After drug was administered, patient experienced the following side effects: aortic thrombosis, intracardiac thrombus. Aprotinin dosage: unknown. During the same period patient was treated with HEPARIN, PROTAMINE SULPHATE, RED BLOOD CELLS, FRESH FROZEN PLASMA, PLATELETS. Patient died.


Aprotinin Side Effects Report #4764845-0
Aprotinin side effect was reported by a Physician from UNITED STATES on Aug 25, 2005. Female patient was diagnosed with surgery  and was treated with Aprotinin. After drug was administered, patient experienced the following side effects: aortic thrombosis. Aprotinin dosage: unknown. Patient died on 07/01/2005.

Aprotinin Side Effects Report #4854223-8
Aprotinin side effect was reported by a Consumer or non-health professional from UNITED STATES on Dec 09, 2005. Female patient was treated with Aprotinin. After drug was administered, patient experienced the following side effects: aortic thrombosis, procedural complication. Aprotinin dosage: unknown. Patient died on 07/01/2005.