Bosentan and condition aggravated Patient Reports February 09, 2010

Bosentan Side Effects Report #4875777-1
Bosentan side effect was reported by a Physician from FRANCE on Dec 22, 2005. Female patient, 76 years of age, was diagnosed with pulmonary hypertension  and was treated with Bosentan. After drug was administered, patient experienced the following side effects: abdominal pain , anaesthetic complication, blood pressure systolic decreased, cardiac failure, condition aggravated, cytolytic hepatitis, fall , femur fracture, haemodynamic instability. Bosentan dosage: unknown. During the same period patient was treated with MORPHINE, OXYGEN, SINTROM, FUROSEMIDE, CACIT, REMEGEL. Patient was hospitalized. Patient died on 01/01/2004.

Bosentan Side Effects Report #4802962-7
Bosentan side effect was reported by a Consumer or non-health professional from SOUTH AFRICA on Oct 04, 2005. Male patient, 25 years of age, weighting 147.7 lb, was diagnosed with pulmonary hypertension  and was treated with Bosentan. After drug was administered, patient experienced the following side effects: condition aggravated, disease progression, pulmonary hypertension , venoocclusive disease. Bosentan dosage: 62.5 MG, BID, ORAL; 125 MG, BID, ORAL. During the same period patient was treated with WARFARIN. Patient died on 05/01/2005.

Bosentan Side Effects Report #6081439-8
Bosentan side effect was reported by a Physician from UNITED STATES on Jan 28, 2009. Female patient, 47 years of age, was diagnosed with pulmonary arterial hypertension and was treated with Bosentan. After drug was administered, patient experienced the following side effects: arthralgia, autoimmune hepatitis, cardiovascular disorder, chest discomfort, chest pain , chronic hepatic failure, condition aggravated, dizziness , dysphagia. Bosentan dosage: 125 MG, BID; 62.5 MG, BID, ORAL. During the same period patient was treated with BOSENTAN VS UNBLINED, SILDENAFIL, DIGOXIN, ALDACTONE, NEXIUM, LASIX, ULTRAM, PREDNISONE. Patient was hospitalized. Patient died on 01/15/2008.