Briplatin and platelet count decreased Patient Reports February 10, 2010

Briplatin Side Effects Report #5748973-9
Briplatin side effect was reported by a Health Professional from JAPAN on May 19, 2008. Male patient, 64 years of age, was diagnosed with rectal cancer and was treated with Briplatin. After drug was administered, patient experienced the following side effects: hepatitis b , neutrophil count decreased, platelet count decreased, white blood cell count decreased. Briplatin dosage: unknown. During the same period patient was treated with CAMPTO. Patient was hospitalized. Patient died on 10/28/2005.

Briplatin Side Effects Report #5780018-7
Briplatin side effect was reported by a Consumer or non-health professional from UNITED STATES on June 17, 2008. Male patient, 77 years of age, weighting 132.3 lb, was diagnosed with pleural mesothelioma malignant and was treated with Briplatin. After drug was administered, patient experienced the following side effects: febrile neutropenia, interstitial lung disease, liver disorder, platelet count decreased, renal impairment. Briplatin dosage: unknown. During the same period patient was treated with ALIMTA, PANVITAN, CYANOCOBALAMIN, AMARYL, BASEN, CELTECT, BISOLVON, OXYCONTIN. Patient was hospitalized. Patient died.

Briplatin Side Effects Report #5802649-8
Briplatin side effect was reported by a Consumer or non-health professional from UNITED STATES on July 03, 2008. Male patient, 77 years of age, weighting 132.3 lb, was diagnosed with pleural mesothelioma malignant, febrile neutropenia and was treated with Briplatin. After drug was administered, patient experienced the following side effects: febrile neutropenia, interstitial lung disease, liver disorder, platelet count decreased, renal impairment. Briplatin dosage: unknown. During the same period patient was treated with ALIMTA, PAZUCROSS, MEROPEN, PANVITAN, CYANOCOBALAMIN, AMARYL, BASEN, CELTECT. Patient was hospitalized. Patient died on 05/13/2008.

Briplatin Side Effects Report #5807027-3
Briplatin side effect was reported by a Consumer or non-health professional from UNITED STATES on July 10, 2008. Male patient, 77 years of age, weighting 132.3 lb, was diagnosed with pleural mesothelioma malignant, febrile neutropenia and was treated with Briplatin. After drug was administered, patient experienced the following side effects: febrile neutropenia, interstitial lung disease, liver disorder, platelet count decreased, renal impairment. Briplatin dosage: unknown. During the same period patient was treated with ALIMTA, PAZUCROSS, MEROPEN, PANVITAN, CYANOCOBALAMIN, AMARYL, BASEN, CELTECT. Patient was hospitalized. Patient died on 05/13/2008.


Briplatin Side Effects Report #5526627-1
Briplatin side effect was reported by a Health Professional from JAPAN on Nov 21, 2007. Male patient, 75 years of age, was diagnosed with pleural mesothelioma malignant and was treated with Briplatin. After drug was administered, patient experienced the following side effects: anaemia, diarrhoea, platelet count decreased, renal impairment, white blood cell count decreased. Briplatin dosage: 85 MG/M2 1/1 DAY. 02-MAY-2007 TO 02-MAY-2007.. During the same period patient was treated with ALIMTA, PANVITAN, MASBLON H, KYTRIL, DECADRON, ZANTAC, FOSMICIN, PRIMPERAN. Patient was hospitalized. Patient recovered.

Briplatin Side Effects Report #5563302-1
Briplatin side effect was reported by a Consumer or non-health professional from UNITED STATES on Dec 14, 2007. Male patient, 75 years of age, weighting 123.5 lb, was diagnosed with pleural mesothelioma malignant and was treated with Briplatin. After drug was administered, patient experienced the following side effects: anaemia, diarrhoea, malignant neoplasm progression, neutrophil count decreased, platelet count decreased, renal impairment, shock, white blood cell count decreased. Briplatin dosage: unknown. During the same period patient was treated with ALIMTA, PANVITAN, MASBLON H, KYTRIL, DECADRON, ZANTAC, FOSMICIN, PRIMPERAN. Patient was hospitalized and became disabled. Patient died on 09/14/2007.

Briplatin Side Effects Report #5605483-7
Briplatin side effect was reported by a Consumer or non-health professional from UNITED STATES on Jan 23, 2008. Male patient, 75 years of age, weighting 123.5 lb, was diagnosed with pleural mesothelioma malignant and was treated with Briplatin. After drug was administered, patient experienced the following side effects: anaemia, aspartate aminotransferase increased, diarrhoea, lymphocyte count decreased, malignant neoplasm progression, nausea , neutrophil count decreased, platelet count decreased, renal impairment. Briplatin dosage: unknown. During the same period patient was treated with ALIMTA, PANVITAN, MASBLON H, KYTRIL, DECADRON, ZANTAC, FOSMICIN, PRIMPERAN. Patient was hospitalized and became disabled. Patient died on 09/14/2007.

Briplatin Side Effects Report #5608804-4
Briplatin side effect was reported by a Consumer or non-health professional from UNITED STATES on Jan 30, 2008. Male patient, 75 years of age, weighting 123.5 lb, was diagnosed with pleural mesothelioma malignant and was treated with Briplatin. After drug was administered, patient experienced the following side effects: anaemia, aspartate aminotransferase increased, diarrhoea, lymphocyte count decreased, malignant neoplasm progression, nausea , neutrophil count decreased, platelet count decreased, renal function test abnormal. Briplatin dosage: unknown. During the same period patient was treated with ALIMTA, PANVITAN, MASBLON H, KYTRIL, DECADRON, ZANTAC, FOSMICIN, PRIMPERAN. Patient was hospitalized and became disabled. Patient died on 09/14/2007.

Briplatin Side Effects Report #5796762-1
Briplatin side effect was reported by a Health Professional from JAPAN on June 25, 2008. Male patient, 74 years of age, was diagnosed with pleural mesothelioma malignant and was treated with Briplatin. After drug was administered, patient experienced the following side effects: anaemia, hyperkalaemia, hypoaesthesia, malaise, platelet count decreased. Briplatin dosage: unknown. During the same period patient was treated with ALIMTA, PANVITAN, CYANOCOBALAMIN, MAGMITT, GLYSENNID. Patient recovered.


Briplatin Side Effects Report #5593461-6
Briplatin side effect was reported by a Health Professional from JAPAN on Jan 11, 2008. Male patient, 72 years of age, was diagnosed with pleural mesothelioma malignant and was treated with Briplatin. After drug was administered, patient experienced the following side effects: anaemia, c-reactive protein increased, headache , hepatic function abnormal, hypoalbuminaemia, malignant neoplasm progression, nausea , platelet count decreased, renal impairment. Briplatin dosage: 75 MG TAKEN ON 04-APR-2007 TO 04-APR-2007. During the same period patient was treated with ALIMTA, PANVITAN, CYANOCOBALAMIN, MYSLEE, LOXONIN, MEDICON, CYTOTEC, URSO. Patient was hospitalized. Patient died.

Briplatin Side Effects Report #5593596-8
Briplatin side effect was reported by a Health Professional from JAPAN on Jan 11, 2008. Male patient, 72 years of age, was diagnosed with pleural mesothelioma malignant and was treated with Briplatin. After drug was administered, patient experienced the following side effects: anaemia, c-reactive protein increased, headache , hepatic function abnormal, hypoalbuminaemia, malignant neoplasm progression, nausea , platelet count decreased, renal impairment. Briplatin dosage: 75 MG TAKEN ON 04-APR-2007 TO 04-APR-2007. During the same period patient was treated with ALIMTA, AVASTIN, PANVITAN, CYANOCOBALAMIN, MYSLEE, LOXONIN, MEDICON, CYTOTEC. Patient was hospitalized. Patient died.

Briplatin Side Effects Report #5602596-0
Briplatin side effect was reported by a Health Professional from JAPAN on Jan 22, 2008. Male patient, 72 years of age, was diagnosed with pleural mesothelioma malignant and was treated with Briplatin. After drug was administered, patient experienced the following side effects: anaemia, c-reactive protein increased, headache , hepatic function abnormal, hypoalbuminaemia, malignant neoplasm progression, nausea , platelet count decreased, renal impairment. Briplatin dosage: 75 MG TAKEN ON 04-APR-2007 TO 04-APR-2007. During the same period patient was treated with ALIMTA, PANVITAN, CYANOCOBALAMIN, MYSLEE, LOXONIN, MEDICON, CYTOTEC, URSO. Patient was hospitalized. Patient died.

Briplatin Side Effects Report #5718331-1
Briplatin side effect was reported by a Consumer or non-health professional from JAPAN on Apr 22, 2008. Male patient, 70 years of age, weighting 141.1 lb, was diagnosed with pleural mesothelioma malignant and was treated with Briplatin. After drug was administered, patient experienced the following side effects: anorexia, blood albumin decreased, blood bilirubin increased, blood urea increased, gastric ulcer haemorrhage, haematocrit decreased, haemoglobin decreased, platelet count decreased, rash . Briplatin dosage: unknown. During the same period patient was treated with ALIMTA, PANVITAN, DECADRON, FOLIC ACID, CYANOCOBALAMIN, KYTRIL, DAONIL, URSO. Patient recovered.

Briplatin Side Effects Report #5508618-X
Briplatin side effect was reported by a Health Professional from JAPAN on Nov 06, 2007. Male patient, 68 years of age, was diagnosed with pleural mesothelioma malignant and was treated with Briplatin. After drug was administered, patient experienced the following side effects: anaemia, lymphocyte count decreased, neutrophil count decreased, platelet count decreased, renal impairment, white blood cell count decreased. Briplatin dosage: unknown. During the same period patient was treated with ALIMTA, PANVITAN, METHYCOBAL. Patient was hospitalized and became disabled. Patient recovered.


Briplatin Side Effects Report #5525285-X
Briplatin side effect was reported by a Consumer or non-health professional from UNITED STATES on Nov 21, 2007. Male patient, 67 years of age, weighting 101.4 lb, was diagnosed with pleural mesothelioma malignant and was treated with Briplatin. After drug was administered, patient experienced the following side effects: anaemia, lymphocyte count decreased, myelodysplastic syndrome, neutrophil count decreased, platelet count decreased, renal impairment, white blood cell count decreased. Briplatin dosage: unknown. During the same period patient was treated with ALIMTA, GEMZAR, PANVITAN, CYANOCOBALAMIN. Patient was hospitalized and became disabled. Patient recovered.

Briplatin Side Effects Report #5599882-X
Briplatin side effect was reported by a Consumer or non-health professional from UNITED STATES on Jan 18, 2008. Male patient, 67 years of age, weighting 101.4 lb, was diagnosed with pleural mesothelioma malignant and was treated with Briplatin. After drug was administered, patient experienced the following side effects: anaemia, lymphocyte count decreased, malignant neoplasm progression, myelodysplastic syndrome, neutrophil count decreased, platelet count decreased, reflux oesophagitis, renal impairment, white blood cell count decreased. Briplatin dosage: unknown. During the same period patient was treated with PARAPLATIN, ALIMTA, GEMZAR, PANVITAN, CYANOCOBALAMIN, TAKEPRON, KYTRIL, DECADRON. Patient was hospitalized and became disabled. Patient died on 12/07/2007.

Briplatin Side Effects Report #5806846-7
Briplatin side effect was reported by a Health Professional from JAPAN on July 07, 2008. Male patient, 62 years of age, was diagnosed with peritoneal mesothelioma malignant and was treated with Briplatin. After drug was administered, patient experienced the following side effects: blood urea increased, c-reactive protein increased, lymphocyte count decreased, malaise, nausea , neutrophil count decreased, platelet count decreased, renal disorder. Briplatin dosage: unknown. During the same period patient was treated with ALIMTA, PANVITAN, CYANOCOBALAMIN, RILMAZAFONE, TAKEPRON, MOBIC, FENTANYL TRANSDERMAL SYSTEM, MAGMITT. Patient was hospitalized. Patient recovered.

Briplatin Side Effects Report #5198414-8
Briplatin side effect was reported by a Physician from JAPAN on Dec 28, 2006. Female patient, 63 years of age, was diagnosed with non-small cell lung cancer and was treated with Briplatin. After drug was administered, patient experienced the following side effects: disseminated intravascular coagulation, platelet count decreased, pneumonia , renal impairment, subarachnoid haemorrhage, white blood cell count decreased. Briplatin dosage: unknown. During the same period patient was treated with NAVELBINE. Patient died on 10/30/2006.

Briplatin Side Effects Report #5313517-2
Briplatin side effect was reported by a Health Professional from JAPAN on Apr 13, 2007. Male patient, 30 years of age, was diagnosed with lung adenocarcinoma and was treated with Briplatin. After drug was administered, patient experienced the following side effects: diarrhoea, disseminated intravascular coagulation, gastrointestinal oedema, neutropenic colitis, neutrophil count decreased, platelet count decreased. Briplatin dosage: 1ST COURSE ON 16APR02 (80 MG.M2). During the same period patient was treated with NAVELBINE, GASTER, ALLOID, MAGNESIUM OXIDE, MS CONTIN. Patient was hospitalized. Patient recovered.


Briplatin Side Effects Report #5237277-9
Briplatin side effect was reported by a Physician from JAPAN on Feb 07, 2007. Male patient, 63 years of age, was treated with Briplatin. After drug was administered, patient experienced the following side effects: disseminated intravascular coagulation, platelet count decreased, pneumonia , renal impairment, subarachnoid haemorrhage, white blood cell count decreased. Briplatin dosage: unknown. During the same period patient was treated with NAVELBINE. Patient died on 10/30/2006.