Clofarabine and dehydration 
Clofarabine and dehydration Patient Reports February 10, 2010
Clofarabine Side Effects Report #5580117-9
Clofarabine side effect was reported by a Health Professional from UNITED STATES on Dec 27, 2007. Male patient, weighting 183.4 lb, was diagnosed with stem cell transplant and was treated with Clofarabine. After drug was administered, patient experienced the following side effects: ascites, clostridial infection, colitis, dehydration, dyspnoea, gastrointestinal disorder, ischaemia, pseudomembranous colitis. Clofarabine dosage: 88 MG DAILY IV DRIP. During the same period patient was treated with CAMPATH, MELPHALAN. Patient was hospitalized. Patient recovered.
Clofarabine Side Effects Report #4847954-7
Clofarabine side effect was reported by a Consumer or non-health professional from UNITED STATES on Nov 22, 2005. Male patient, 50 years of age, was diagnosed with pancreatic carcinoma and was treated with Clofarabine. After drug was administered, patient experienced the following side effects: dehydration, diarrhoea, endoscopy abnormal, nausea
. Clofarabine dosage: 232 MG IV. During the same period patient was treated with PANCREASE, TEMAZEPAM, HUMALOG, PROPO N, DURAGESIC, REGLAN, ATIVAN, CELEBREX. Patient was hospitalized. Patient recovered.Clofarabine Side Effects Report #4907246-4
Clofarabine side effect was reported by a Consumer or non-health professional from UNITED STATES on Jan 25, 2006. Male patient, 50 years of age, was diagnosed with pancreatic carcinoma and was treated with Clofarabine. After drug was administered, patient experienced the following side effects: abdominal pain
, dehydration, diarrhoea, nausea . Clofarabine dosage: 232 MG IV. During the same period patient was treated with PANCREASE, TEMAZEPAM, HUMALOG, PROFOX N, DURAGESIC, CELEBREX, LORAZEPAM, DEXAMETHASONE PHOSPHATE. Patient was hospitalized. Patient recovered.Clofarabine Side Effects Report #5691777-6
Clofarabine side effect was reported by a Physician from UNITED STATES on Mar 17, 2008. Female patient, 66 years of age, weighting 199.5 lb, was diagnosed with myeloid leukaemia and was treated with Clofarabine. After drug was administered, patient experienced the following side effects: anxiety
, blood culture positive, blood pressure diastolic decreased, blood pressure increased, body temperature decreased, cardiomegaly, culture urine positive, dehydration, diarrhoea. Clofarabine dosage: 30 MG/M2, QDX5, INTRAVENOUS, 20 MG/M2, QDX5, INTRAVENOUS. During the same period patient was treated with ESTRADIOL, SYNTHROID, LIPITOR, METOPROLOL TARTRATE, AMIKACIN, PROTONIX, VALTREX. Patient was hospitalized. Patient recovered.Clofarabine Side Effects Report #5955873-8
Clofarabine side effect was reported by a Physician from UNITED STATES on Oct 31, 2008. Female patient, 66 years of age, weighting 199.5 lb, was diagnosed with myeloid leukaemia and was treated with Clofarabine. After drug was administered, patient experienced the following side effects: anxiety
, blood pressure diastolic decreased, cardiomegaly, dehydration, diarrhoea, dyspnoea, gastrointestinal haemorrhage, klebsiella infection, nausea . Clofarabine dosage: 30 MG/M2,QDX5, INTRAVENOUS : 20 MG/M2, QDX5, INTRAVENOUS. During the same period patient was treated with ESTRADIOL, SYNTHROID, LIPITOR, METOPROLOL TARTRATE, AMIKACIN, PROTONIX, VALTREX. Patient was hospitalized. Patient recovered.Clofarabine Side Effects Report #5054452-7
Clofarabine side effect was reported by a Health Professional from UNITED STATES on June 29, 2006. Male patient, 68 years of age, was diagnosed with myelodysplastic syndrome and was treated with Clofarabine. After drug was administered, patient experienced the following side effects: blood creatinine increased, dehydration, hypotension, muscular weakness. Clofarabine dosage: 62.7 MG QD X 5 IV. Patient was hospitalized. Patient recovered.
Clofarabine Side Effects Report #5064587-0
Clofarabine side effect was reported by a Physician from UNITED STATES on July 19, 2006. Male patient, 68 years of age, was diagnosed with myelodysplastic syndrome and was treated with Clofarabine. After drug was administered, patient experienced the following side effects: aspergillosis, asthenia, blood creatinine increased, blood culture positive, blood pressure diastolic decreased, blood urea increased, dehydration, dialysis
, fungus culture positive. Clofarabine dosage: 62.7 MG QD X 5 IV. Patient was hospitalized. Patient died on 07/17/2006.Clofarabine Side Effects Report #5098011-9
Clofarabine side effect was reported by a Health Professional from UNITED STATES on Aug 22, 2006. Male patient, 68 years of age, weighting 194.0 lb, was diagnosed with myelodysplastic syndrome and was treated with Clofarabine. After drug was administered, patient experienced the following side effects: aspergillosis, blood creatinine increased, blood culture positive, blood urea increased, dehydration, dialysis
, hypotension, muscular weakness. Clofarabine dosage: 62.7 MG QD X 5 IV. During the same period patient was treated with BACTRIM, ITRACONAZOLE, PROCRIT. Patient was hospitalized. Patient died on 07/17/2006.Clofarabine Side Effects Report #5682504-7
Clofarabine side effect was reported by a Pharmacist from UNITED STATES on Mar 26, 2008. Female patient, weighting 132.5 lb, was diagnosed with lymphoma
and was treated with Clofarabine. After drug was administered, patient experienced the following side effects: anaemia, anorexia, condition aggravated, dehydration, nausea , nephrolithiasis, renal failure acute, renal injury. Clofarabine dosage: unknown. During the same period patient was treated with IBUPROFEN. Patient was hospitalized. Patient recovered.Clofarabine Side Effects Report #5869466-4
Clofarabine side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on July 18, 2008. Female patient, 79 years of age, was diagnosed with acute myeloid leukaemia and was treated with Clofarabine. After drug was administered, patient experienced the following side effects: confusional state, dehydration, diarrhoea, fall
, haemorrhage intracranial, hypotension, lethargy, sepsis , thrombocytopenia. Clofarabine dosage: 40 MG, QDX5, INTRAVENOUS. During the same period patient was treated with METOCLOPRAMIDE, ALLOPURINOL, HYPROMELLOSE, ACYCLOVIR, SULFAMETHOXAZOLE AND TRIMETHOPRIM, PEPTAC, ONDANZETRON, OMEPRAZOLE. Patient died on 03/01/2005.Clofarabine Side Effects Report #5869466-4
Clofarabine side effect was reported by a Physician from UNITED KINGDOM on July 18, 2008. Female patient, 79 years of age, was diagnosed with acute myeloid leukaemia and was treated with Clofarabine. After drug was administered, patient experienced the following side effects: confusional state, dehydration, diarrhoea, fall
, haemorrhage intracranial, hypotension, lethargy, sepsis , thrombocytopenia. Clofarabine dosage: 40 MG, QDX5, INTRAVENOUS. During the same period patient was treated with METOCLOPRAMIDE, ALLOPURINOL, HYDROMELLOSE, ACYCLOVIR, SULFAMETHOXAZOLE AND TRIMETHOPRIM, PEPTAC, ONDANSETRON, OMEPRAZOLE. Patient died on 03/01/2005.Clofarabine Side Effects Report #4753730-6
Clofarabine side effect was reported by a Health Professional from UNITED KINGDOM on Aug 16, 2005. Male patient, 78 years of age, was diagnosed with acute myeloid leukaemia and was treated with Clofarabine. After drug was administered, patient experienced the following side effects: anaphylactic shock, blood creatine increased, blood urea increased, cardiac arrest
, dehydration, fluid overload, haematuria, loss of consciousness, neutrophil count increased. Clofarabine dosage: 51 MG QD X 5 IV. During the same period patient was treated with MODURET, AMLODIINE, BONEFOS, NITRAZEPAM, ONDANSETRON, CIPROFLOXACIN. Patient was hospitalized. Patient died on 05/10/2004.Clofarabine Side Effects Report #5041849-4
Clofarabine side effect was reported by a Physician from UNITED STATES on June 26, 2006. Female patient, 74 years of age, was diagnosed with acute myeloid leukaemia and was treated with Clofarabine. After drug was administered, patient experienced the following side effects: atrial fibrillation
, cardiac output decreased, cellulitis , contusion, dehydration, diarrhoea, fall , haematoma, hypotension. Clofarabine dosage: 45 MG QD X 5 IV. During the same period patient was treated with CYTARABINE, VALACYCLOVIR, ITRACONAZOLE, OSCAL, METOPROLOL TARTRATE. Patient was hospitalized. Patient recovered.Clofarabine Side Effects Report #5044361-1
Clofarabine side effect was reported by a Physician from UNITED STATES on June 21, 2006. Female patient, 74 years of age, was diagnosed with acute myeloid leukaemia and was treated with Clofarabine. After drug was administered, patient experienced the following side effects: atrial fibrillation
, cellulitis , contusion, dehydration, diarrhoea, fall , haematoma, laceration, nausea . Clofarabine dosage: 45 MG QD X 5 IV. During the same period patient was treated with CYTARABINE, VALACYCLOVIR, ITRACONAZOLE, OSCAL, METOPROLOL TARTRATE. Patient was hospitalized. Patient recovered.Clofarabine Side Effects Report #4725096-9
Clofarabine side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on July 12, 2005. Male patient, 71 years of age, was diagnosed with acute myeloid leukaemia and was treated with Clofarabine. After drug was administered, patient experienced the following side effects: arrhythmia
, atrial fibrillation , cardiac arrest , dehydration, diarrhoea, dyspnoea, haemodialysis, hyperkalaemia. Clofarabine dosage: 20 MG/M2 IV. During the same period patient was treated with VORICONAZOLE, AMIODARONE, METRONIDAZOLE, SEPTRIN, ACYCLOVIR, POTASSIUM CHLORIDE, METOCLOPRAMIDE. Patient was hospitalized. Patient died on 06/11/2005.Clofarabine Side Effects Report #4726159-4
Clofarabine side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on July 12, 2005. Male patient, 71 years of age, was diagnosed with acute myeloid leukaemia and was treated with Clofarabine. After drug was administered, patient experienced the following side effects: atrial fibrillation
, cardiac arrest , dehydration, diarrhoea, dyspnoea, effusion, haemodialysis, hyperkalaemia. Clofarabine dosage: 20 MG/M2 IV. During the same period patient was treated with VORICONAZOLE, AMIODARONE, METRONIDAZOLE, SEPTRIN, ACYCLOVIR, POTASSIUM CHLORIDE, METOCLOPRAMIDE. Patient was hospitalized. Patient died on 06/11/2005.Clofarabine Side Effects Report #5188784-9
Clofarabine side effect was reported by a Physician from UNITED STATES on Dec 11, 2006. Female patient, 68 years of age, was diagnosed with acute myeloid leukaemia and was treated with Clofarabine. After drug was administered, patient experienced the following side effects: alopecia, chills, confusional state, decreased appetite, dehydration, diarrhoea, febrile neutropenia, haemangioma. Clofarabine dosage: unknown. During the same period patient was treated with HIDAC, ACYCLOVIR, AMILORIDE HYDROCHLORIDE, ABELCET, TYLENOL, BENADRYL, HYDROCORTISONE. Patient was hospitalized. Patient died on 11/18/2006.
Clofarabine Side Effects Report #5195681-1
Clofarabine side effect was reported by a Health Professional from UNITED STATES on Dec 19, 2006. Female patient, 68 years of age, weighting 142.9 lb, was diagnosed with acute myeloid leukaemia and was treated with Clofarabine. After drug was administered, patient experienced the following side effects: acute myeloid leukaemia recurrent, alopecia, appetite disorder, confusional state, dehydration, diarrhoea, febrile neutropenia. Clofarabine dosage: 40 MG/M2 QD X 5 IV. During the same period patient was treated with HIDAC, ACYCLOVIR, AMILORIDE HYDROCHLORIDE, ABELCET, TYLENOL, BENADRYL. Patient was hospitalized. Patient died on 11/18/2006.
Clofarabine Side Effects Report #4984252-5
Clofarabine side effect was reported by a Health Professional from UNITED KINGDOM on Apr 05, 2006. Female patient, 68 years of age, was diagnosed with acute myeloid leukaemia and was treated with Clofarabine. After drug was administered, patient experienced the following side effects: anaemia, atrial fibrillation
, blister, blood potassium decreased, cardiac failure, crepitations, dehydration, dialysis , diarrhoea. Clofarabine dosage: 30 MG/M2 QD X 5 IV. During the same period patient was treated with DAUNORUBICIN, SEPTRIN. Patient was hospitalized. Patient died on 04/09/2006.Clofarabine Side Effects Report #5011568-9
Clofarabine side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on May 10, 2006. Female patient, 68 years of age, was diagnosed with acute myeloid leukaemia and was treated with Clofarabine. After drug was administered, patient experienced the following side effects: anaemia, atrial fibrillation
, blood potassium decreased, cardiac failure, dehydration, dialysis , diarrhoea, electrocardiogram poor r-wave progression. Clofarabine dosage: 30 MG/M2 QD X 5 IV. During the same period patient was treated with DAUNORUBICIN, SEPTRIN. Patient was hospitalized. Patient died on 04/09/2006.Clofarabine Side Effects Report #5621911-5
Clofarabine side effect was reported by a Physician from UNITED STATES on Jan 23, 2008. Female patient, 66 years of age, weighting 210.3 lb, was diagnosed with acute myeloid leukaemia and was treated with Clofarabine. After drug was administered, patient experienced the following side effects: blood culture positive, blood pressure increased, culture urine positive, dehydration, diarrhoea, fluid overload, gastrointestinal haemorrhage, laboratory test interference, lung neoplasm. Clofarabine dosage: 30 MG/M2, QDX5, INTRAVENOUS, 20 MG/M2, QDX5, INTRAVENOUS. During the same period patient was treated with ESTRADIOL, SYNTHROID, LIPITOR, METOPROLOL TARTRATE, AMIKACIN, PROTONIX, VALTREX. Patient was hospitalized. Patient recovered.
Clofarabine Side Effects Report #5678770-4
Clofarabine side effect was reported by a Physician from CANADA on Mar 14, 2008. Female patient, child 9 years of age, weighting 74.96 lb, was diagnosed with acute lymphocytic leukaemia and was treated with Clofarabine. After drug was administered, patient experienced the following side effects: abdominal pain
, arterial occlusive disease, cerebrovascular accident, dehydration, diarrhoea, platelet count decreased, pulmonary oedema, radiation injury, skin hypertrophy. Clofarabine dosage: 52 MG/M2, INTRAVENOUS; 40 MG/M2, QDX5, INTRAVENOUS. During the same period patient was treated with NEUPOGEN, PENTAMIDINE, FLUCONAZOLE, PENICILLIN, LEVOTHYROXINE, LANSOPRAZOLE, MELATONIN, NITROFURANTOIN. Patient was hospitalized. Patient died on 02/25/2008.Clofarabine Side Effects Report #6055058-3
Clofarabine side effect was reported by a Physician from CANADA on Jan 15, 2009. Female patient, child 9 years of age, weighting 74.96 lb, was diagnosed with acute lymphocytic leukaemia and was treated with Clofarabine. After drug was administered, patient experienced the following side effects: abdominal pain
, activated partial thromboplastin time prolonged, arterial occlusive disease, asthenia, bone marrow transplant , cerebral infarction, cerebrovascular accident, dehydration, diarrhoea. Clofarabine dosage: 52 MG/M2, QDX5, INTRAVENOUS, 40 MG/M2, QDX5, INTRAVENOUS. During the same period patient was treated with FILGRASTIM, PENTAMIDINE, FLUCONAZOLE, PENICILLIN NOS, LEVOTHYROXINE, LANSOPRAZOLE, MELATONIN. Patient was hospitalized. Patient died on 02/25/2008.Clofarabine Side Effects Report #5877444-4
Clofarabine side effect was reported by a Physician from UNITED STATES on Sept 03, 2008. Male patient, 57 years of age, weighting 198.4 lb, was diagnosed with acute lymphocytic leukaemia and was treated with Clofarabine. After drug was administered, patient experienced the following side effects: anaemia, bacterial infection
, culture throat positive, culture urine positive, dehydration, escherichia sepsis, febrile neutropenia, hypoxia, multi-organ failure. Clofarabine dosage: 425 MG, QDX5, INTRAVENOUS. During the same period patient was treated with CYTARABINE. Patient died on 05/31/2008.Clofarabine Side Effects Report #5887329-5
Clofarabine side effect was reported by a Physician from UNITED STATES on Sept 10, 2008. Male patient, 57 years of age, weighting 198.4 lb, was diagnosed with acute lymphocytic leukaemia and was treated with Clofarabine. After drug was administered, patient experienced the following side effects: anaemia, culture throat positive, culture urine positive, dehydration, escherichia infection, multi-organ failure, neutropenic infection, organising pneumonia, parainfluenzae virus infection. Clofarabine dosage: 425 MG, QDX5, INTRAVENOUS. During the same period patient was treated with CYTARABINE, ACYCLOVIR, DOXYCYCLINE, LEVAQUIN, MICAFUNGIN, NOXAFIL, VORICONAZOLE. Patient died on 05/31/2008.
Clofarabine Side Effects Report #5248305-9
Clofarabine side effect was reported by a Physician from NETHERLANDS on Jan 29, 2007. Male patient, 15 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with Clofarabine. After drug was administered, patient experienced the following side effects: ascites, blood amylase increased, blood bilirubin increased, conjunctival haemorrhage, conjunctivitis, convulsion, culture stool positive, dehydration, diarrhoea. Clofarabine dosage: 100 MG QD X 5 IV. During the same period patient was treated with GRANISETRON, DEXAMETHASONE, ALLOPURINOL, SDD CAPSULES, BACTRIMEL, AMPHOTERICINE, FUNGISONE, ACETAMINOPHEN. Patient was hospitalized. Patient recovered.
Clofarabine Side Effects Report #4680963-X
Clofarabine side effect was reported by a Physician from on May 19, 2005. Male patient, 15 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with Clofarabine. After drug was administered, patient experienced the following side effects: ascites, bacteria stool identified, blood bilirubin increased, cerebral ischaemia, conjunctival haemorrhage, conjunctivitis, convulsion, dehydration, diarrhoea. Clofarabine dosage: 100 MG QD X 5 IV. During the same period patient was treated with GRANISETRON, DEXAMETHASONE, ALLOPURINOL, SDD CAPSULES, BACTRIMEL, AMPHOTERICINE, FUNGISONE, ACETAMINOPHEN. Patient was hospitalized. Patient recovered.
Clofarabine Side Effects Report #5491238-3
Clofarabine side effect was reported by a Physician from UNITED STATES on Oct 11, 2007. Male patient, 14 years of age, weighting 202.8 lb, was diagnosed with acute lymphocytic leukaemia and was treated with Clofarabine. After drug was administered, patient experienced the following side effects: dehydration, diarrhoea, hypotension, pancreatitis. Clofarabine dosage: 40 MG/M2. During the same period patient was treated with CYTARABINE. Patient was hospitalized. Patient recovered.
Clofarabine Side Effects Report #5908902-1
Clofarabine side effect was reported by a Health Professional from UNITED STATES on Sept 17, 2008. Male patient, 69 years of age, weighting 231.5 lb, was diagnosed with acute leukaemia and was treated with Clofarabine. After drug was administered, patient experienced the following side effects: atelectasis, biopsy skin abnormal, blood lactate dehydrogenase increased, bundle branch block right, cardiac failure congestive, cardiomyopathy
, dehydration, enterobacter sepsis, fusarium infection. Clofarabine dosage: 55 MG, QDX5, ORAL. During the same period patient was treated with TOPROL, ALBUTEROL, FLONASE, ASPIRIN, PLAVIX, NORVASC, PROCRIT, LEVAQUIN. Patient was hospitalized. Patient recovered.Clofarabine Side Effects Report #5623838-1
Clofarabine side effect was reported by a Physician from CANADA on Feb 01, 2008. Female patient, child 9 years of age, was treated with Clofarabine. After drug was administered, patient experienced the following side effects: cerebral artery occlusion, cerebrovascular accident, dehydration, diarrhoea, radiation injury, skin hypertrophy, vasculitis
. Clofarabine dosage: 52 MG/M2, INTRAVENOUS. Patient was hospitalized. Patient recovered.Clofarabine Side Effects Report #5657646-2
Clofarabine side effect was reported by a Physician from CANADA on Feb 27, 2008. Female patient, child 9 years of age, was treated with Clofarabine. After drug was administered, patient experienced the following side effects: abdominal pain
, asthenia, cerebral artery occlusion, cerebrovascular accident, dehydration, diarrhoea, pulmonary oedema, radiation injury, skin hypertrophy. Clofarabine dosage: 52 MG/M2, INTRAVENOUS; 40 MG/M2, QDX5, INTRAVENOUS. Patient was hospitalized. Patient died on 02/25/2008.Clofarabine Side Effects Report #5119084-0
Clofarabine side effect was reported by a Physician from UNITED STATES on Sept 22, 2006. Male patient, 58 years of age, was diagnosed with acute myeloid leukaemia recurrent and was treated with Clofarabine. After drug was administered, patient experienced the following side effects: anxiety
, asthenia, atelectasis, blood creatinine increased, blood phosphorus decreased, dehydration, dermatitis contact, diarrhoea, dyspnoea. Clofarabine dosage: 10 MG/M2 DAILY IV. During the same period patient was treated with CYCLOPHOSPHAMIDE, ACETAMINOPHEN, ALLOPURINOL, HYDROCORTISONE, BACTRIM. Patient was hospitalized. Patient died on 08/30/2006.