Comtess and international normalised ratio increased Patient Reports March 22, 2010

Comtess Side Effects Report #5075751-9
Comtess side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on July 26, 2006. Male patient, 84 years of age, was diagnosed with parkinson's disease  and was treated with Comtess. After drug was administered, patient experienced the following side effects: contusion, international normalised ratio increased, rectal haemorrhage. Comtess dosage: unknown. During the same period patient was treated with WARFARIN, MADOPAR, QUININE SULPHATE, RAMIPRIL, FALODIPINE MR, AMIODARONE HYDROCHLORIDE. Patient was hospitalized and became disabled. Patient recovered.

Comtess Side Effects Report #5097622-4
Comtess side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on Aug 03, 2006. Male patient, 84 years of age, was diagnosed with parkinson's disease  and was treated with Comtess. After drug was administered, patient experienced the following side effects: contusion, international normalised ratio increased, rectal haemorrhage. Comtess dosage: 200 MG; 400 MG (200 MG, 2 IN 1 D) ; 600 MG (200 MG, 3 IN 1 D). During the same period patient was treated with MADOPAR, QUININE SULPHATE, RAMIPRIL, FALODIPINE MR, AMIODARONE HYDROCHLORIDE, FUROSEMIDE. Patient was hospitalized and became disabled. Patient recovered.

Comtess Side Effects Report #5109700-1
Comtess side effect was reported by a Physician from UNITED KINGDOM on Sept 11, 2006. Male patient, 84 years of age, was diagnosed with parkinson's disease  and was treated with Comtess. After drug was administered, patient experienced the following side effects: confusional state, contusion, international normalised ratio increased, rectal haemorrhage, refusal of treatment by relative. Comtess dosage: unknown. During the same period patient was treated with WARFARIN, MADOPAR, QUININE SULPHATE, RAMIPRIL, FELODIPINE, AMIODARONE, FUROSEMIDE. Patient was hospitalized and became disabled. Patient recovered.

Comtess Side Effects Report #5476586-5
Comtess side effect was reported by a Physician from UNITED KINGDOM on Sept 26, 2007. Male patient, 84 years of age, was diagnosed with parkinson's disease  and was treated with Comtess. After drug was administered, patient experienced the following side effects: contusion, international normalised ratio increased, rectal haemorrhage. Comtess dosage: 200 MG, QD. During the same period patient was treated with WARFARIN, MADOPAR, QUININE SULPHATE, RAMIPRIL, FELODIPINE, AMIODARONE HYDROCHLORIDE. Patient was hospitalized and became disabled. Patient recovered.