Elspar and activated partial thromboplastin time prolonged Patient Reports February 09, 2010

Elspar Side Effects Report #4586993-0
Elspar side effect was reported by a Physician from on Feb 10, 2005. Male patient, 55 years of age, was diagnosed with b-cell type acute leukaemia and was treated with Elspar. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, antithrombin iii decreased, blood fibrinogen increased, factor xi deficiency, factor xii deficiency, platelet count decreased, protein c decreased, protein s decreased, thrombosis. Elspar dosage: unknown. During the same period patient was treated with PREDNISONE, FLUDARABINE PHOSPHATE, MITOXANTRONE HYDROCHLORIDE, VINCRISTINE SULPHATE, CYTARABINE. Patient recovered.

Elspar Side Effects Report #6140102-5
Elspar side effect was reported by a Consumer or non-health professional from UNITED STATES on Mar 12, 2009. Male patient, child 7 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with Elspar. After drug was administered, patient experienced the following side effects: abdominal rigidity, activated partial thromboplastin time prolonged, ascites, blood bilirubin increased, blood bilirubin unconjugated increased, blood lactate dehydrogenase increased, haemoglobin decreased, leukaemia cutis, pancreatitis acute. Elspar dosage: unknown. During the same period patient was treated with PREDNISOLONE, VINCRISTINE, DOXORUBICIN, METHOTREXATE. Patient was hospitalized. Patient recovered.

Elspar Side Effects Report #4559757-1
Elspar side effect was reported by a Health Professional from on Jan 14, 2005. Female patient, 48 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with Elspar. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, antithrombin iii decreased, blood fibrinogen decreased, cerebral infarction, prothrombin time prolonged, superior sagittal sinus thrombosis. Elspar dosage: unknown. Patient died.

Elspar Side Effects Report #4778500-4
Elspar side effect was reported by a Health Professional from JAPAN on Jan 14, 2005. Female patient, 48 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with Elspar. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, antithrombin iii decreased, blood fibrinogen decreased, cerebral infarction, prothrombin time prolonged, superior sagittal sinus thrombosis. Elspar dosage: unknown. Patient died.


Elspar Side Effects Report #4826516-1
Elspar side effect was reported by a Health Professional from JAPAN on Jan 14, 2005. Female patient, 48 years of age, weighting 116.8 lb, was diagnosed with acute lymphocytic leukaemia and was treated with Elspar. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, antithrombin iii decreased, blood fibrinogen decreased, cerebral infarction, clonic convulsion, coagulation factor ix level decreased, depressed level of consciousness, eyelid oedema, face oedema. Elspar dosage: unknown. During the same period patient was treated with PIRARUBICIN, VINDESINE, CYCLOPHOSPHAMIDE, PREDNISOLONE. Patient died on 12/05/1990.

Elspar Side Effects Report #4585587-0
Elspar side effect was reported by a Physician from on Jan 14, 2005. Male patient, child 3 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with Elspar. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, antithrombin iii decreased, encephalomalacia, fibrin degradation products increased, hyponatraemia, infarction, intracranial pressure increased, mucormycosis, neutropenia. Elspar dosage: unknown. During the same period patient was treated with VINCRISTINE SULPHATE, PREDNISONE. Patient died.

Elspar Side Effects Report #4585587-0
Elspar side effect was reported by a Physician from on Jan 14, 2005. Male patient, child 3 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with Elspar. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, antithrombin iii decreased, encephalomalacia, fibrin degradation products increased, hyponatraemia, infarction, intracranial pressure increased, mucormycosis, neutropenia. Elspar dosage: unknown. During the same period patient was treated with VINCRISTINE SULPHATE, PREDNISONE. Patient died.

Elspar Side Effects Report #4586235-6
Elspar side effect was reported by a Health Professional from on Jan 14, 2005. Female patient, 14 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with Elspar. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, anorexia, ascites, asthenia, back pain , blood sodium decreased, haematocrit decreased, haemoglobin decreased, haemorrhagic cyst. Elspar dosage: unknown. Patient was hospitalized. Patient recovered.