Fludarabine and chronic lymphocytic leukaemia transformation Patient Reports February 10, 2010

Fludarabine Side Effects Report #4950546-2
Fludarabine side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on Feb 28, 2006. Male patient, 75 years of age, was diagnosed with chronic lymphocytic leukaemia recurrent and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: chronic lymphocytic leukaemia transformation, hepatorenal failure, t-cell lymphoma. Fludarabine dosage: unknown. Patient died.

Fludarabine Side Effects Report #4620152-8
Fludarabine side effect was reported by a Consumer or non-health professional from on Mar 08, 2005. Male patient, 71 years of age, was diagnosed with chronic lymphocytic leukaemia and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: chronic lymphocytic leukaemia transformation, epstein-barr virus antigen positive, laboratory test abnormal. Fludarabine dosage: unknown. During the same period patient was treated with CYCLOPHOSPHAMIDE, MITOXANTRONE. Patient died.

Fludarabine Side Effects Report #4620145-0
Fludarabine side effect was reported by a Consumer or non-health professional from on Mar 08, 2005. Male patient, 67 years of age, was diagnosed with chronic lymphocytic leukaemia and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: chronic lymphocytic leukaemia transformation. Fludarabine dosage: 25 MG/M2, INTRAVENOUS. During the same period patient was treated with CYCLOPHOSPHAMIDE, MITOXANTRONE. Patient died.

Fludarabine Side Effects Report #4653517-9
Fludarabine side effect was reported by a Consumer or non-health professional from on Apr 20, 2005. Male patient, 67 years of age, was diagnosed with chronic lymphocytic leukaemia and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: chronic lymphocytic leukaemia transformation. Fludarabine dosage: 125 MG/M2, 1 IN 1 CYCLE, INTRAVENOUS (NOT OTHERWISE SPECIFIED); 3 COURSE. Patient died.


Fludarabine Side Effects Report #4620041-9
Fludarabine side effect was reported by a Consumer or non-health professional from on Mar 08, 2005. Male patient, 60 years of age, was diagnosed with chronic lymphocytic leukaemia and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: chronic lymphocytic leukaemia transformation, therapeutic response decreased. Fludarabine dosage: 25 MG/M2, INTRAVENOUS. Patient died.

Fludarabine Side Effects Report #4620146-2
Fludarabine side effect was reported by a Consumer or non-health professional from on Mar 08, 2005. Female patient, 57 years of age, was diagnosed with chronic lymphocytic leukaemia and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: chronic lymphocytic leukaemia transformation, epstein-barr virus antigen positive, epstein-barr virus infection. Fludarabine dosage: 25 MG/M2 , INTRAVENOUS. Patient died.

Fludarabine Side Effects Report #4620151-6
Fludarabine side effect was reported by a Consumer or non-health professional from on Mar 08, 2005. Male patient, 57 years of age, was diagnosed with chronic lymphocytic leukaemia, haemolytic anaemia and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: chronic lymphocytic leukaemia transformation, epstein-barr virus infection, haemolytic anaemia. Fludarabine dosage: 25 MG/M2, INTRAVENOUS. During the same period patient was treated with CYCLOSPORINE, CORTICOSTEROIDS. Patient died.

Fludarabine Side Effects Report #4630616-9
Fludarabine side effect was reported by a Consumer or non-health professional from on Apr 04, 2005. Male patient, 57 years of age, was diagnosed with chronic lymphocytic leukaemia, haemolytic anaemia and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: bone marrow disorder, chronic lymphocytic leukaemia transformation. Fludarabine dosage: 25MG/M2. During the same period patient was treated with STEROIDS NOS, CYCLOSPORINE. Patient died.

Fludarabine Side Effects Report #4620147-4
Fludarabine side effect was reported by a Consumer or non-health professional from on Mar 08, 2005. Male patient, 55 years of age, was diagnosed with chronic lymphocytic leukaemia and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: chronic lymphocytic leukaemia transformation. Fludarabine dosage: unknown. During the same period patient was treated with CYCLOPHOSPHAMIDE, MITOXANTRONE, METHYLPREDNISOLONE, CAMPATH. Patient died.


Fludarabine Side Effects Report #4620156-5
Fludarabine side effect was reported by a Consumer or non-health professional from on Mar 08, 2005. Female patient, 55 years of age, was diagnosed with chronic lymphocytic leukaemia and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: chronic lymphocytic leukaemia transformation, epstein-barr virus antigen positive, laboratory test abnormal. Fludarabine dosage: 25 MG/M2, INTRAVENOUS. Patient died.

Fludarabine Side Effects Report #4620039-0
Fludarabine side effect was reported by a Consumer or non-health professional from on Mar 08, 2005. Male patient, 51 years of age, was diagnosed with chronic lymphocytic leukaemia and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: chronic lymphocytic leukaemia transformation. Fludarabine dosage: 25 MG/M2, INTRAVENOUS. Patient died.

Fludarabine Side Effects Report #4620148-6
Fludarabine side effect was reported by a Consumer or non-health professional from on Mar 08, 2005. Male patient, 47 years of age, was diagnosed with chronic lymphocytic leukaemia and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: chronic lymphocytic leukaemia transformation, epstein-barr virus infection. Fludarabine dosage: 25 MG/M2, INTRAVENOUS. Patient died.

Fludarabine Side Effects Report #4620149-8
Fludarabine side effect was reported by a Consumer or non-health professional from on Mar 08, 2005. Male patient, 42 years of age, was diagnosed with chronic lymphocytic leukaemia and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: chronic lymphocytic leukaemia transformation, disease progression, epstein-barr virus infection. Fludarabine dosage: 25 MG/M2, INTRAVENOUS. Patient died.

Fludarabine Side Effects Report #4620155-3
Fludarabine side effect was reported by a Consumer or non-health professional from on Mar 08, 2005. Male patient, 42 years of age, was diagnosed with chronic lymphocytic leukaemia and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: chronic lymphocytic leukaemia transformation, epstein-barr virus infection. Fludarabine dosage: 25 MG.M2, INTRAVENOUS. Patient recovered.


Fludarabine Side Effects Report #5741516-5
Fludarabine side effect was reported by a Health Professional from ITALY on Mar 18, 2008. Male patient, 60 years of age, was diagnosed with b-cell small lymphocytic lymphoma and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: cachexia, chronic lymphocytic leukaemia transformation, epstein-barr virus test positive, hypochromic anaemia, malaise, splenomegaly. Fludarabine dosage: unknown. During the same period patient was treated with RITUXIMAB. Patient died.

Fludarabine Side Effects Report #4620042-0
Fludarabine side effect was reported by a Consumer or non-health professional from on Mar 08, 2005. Male patient, 67 years of age, was treated with Fludarabine. After drug was administered, patient experienced the following side effects: chronic lymphocytic leukaemia transformation. Fludarabine dosage: unknown. During the same period patient was treated with FLUDARABINE PHOSPHATE, CYCLOPHOSPHAMIDE, MITOXANTRONE, METHYLPREDNISOLONE. Patient died.