Gliadel and hyponatraemia Patient Reports February 10, 2010

Gliadel Side Effects Report #5788147-9
Gliadel side effect was reported by a Consumer or non-health professional from UNITED STATES on June 12, 2008. Female patient was diagnosed with malignant glioma and was treated with Gliadel. After drug was administered, patient experienced the following side effects: arachnoiditis, central nervous system infection, extradural haematoma, hydrocephalus , hyponatraemia, intracranial hypotension, meningitis , postoperative wound infection, pyrexia. Gliadel dosage: unknown. Patient recovered.

Gliadel Side Effects Report #5265064-4
Gliadel side effect was reported by a Health Professional from UNITED STATES on Aug 28, 2006. Male patient, 69 years of age, weighting 186.3 lb, was diagnosed with glioblastoma multiforme and was treated with Gliadel. After drug was administered, patient experienced the following side effects: hyponatraemia, mental status changes, pyrexia. Gliadel dosage: unknown. During the same period patient was treated with CARBATROL, ZANTAC, HYDROCHLOROTHIAZIDE, CHLORIDE, DECADRON, DEPAKOTE. Patient was hospitalized. Patient recovered.

Gliadel Side Effects Report #5093820-4
Gliadel side effect was reported by a Health Professional from UNITED STATES on Aug 29, 2006. Male patient, weighting 186.3 lb, was diagnosed with glioblastoma multiforme and was treated with Gliadel. After drug was administered, patient experienced the following side effects: asthenia, bacteria blood identified, cognitive disorder, dizziness , feeling abnormal, hyponatraemia, laboratory test interference. Gliadel dosage: 7.7 MG PER WAFER ONCE IV. During the same period patient was treated with CARBATROL, ZANTAC, HYDROCHLOROTHIAZIDE, CHLORIDE, DECADRON. Patient was hospitalized. Patient recovered.

Gliadel Side Effects Report #5130262-7
Gliadel side effect was reported by a Health Professional from UNITED STATES on Oct 18, 2006. Female patient, weighting 169.8 lb, was diagnosed with glioblastoma multiforme and was treated with Gliadel. After drug was administered, patient experienced the following side effects: deep vein thrombosis , haemoglobin abnormal, hyponatraemia, incision site complication, intracranial hypotension, pyrexia, venous thrombosis, wound complication. Gliadel dosage: 7.L7 MG PER WAFER ONCE IV. During the same period patient was treated with LEXAPRO, PROTONIX, CHLORIDE, DECADRON, TYLENOL, ATIVAN, VALPROIC ACID. Patient was hospitalized. Patient recovered.


Gliadel Side Effects Report #5130266-4
Gliadel side effect was reported by a Health Professional from UNITED STATES on Oct 18, 2006. Male patient, weighting 172.6 lb, was diagnosed with glioblastoma multiforme and was treated with Gliadel. After drug was administered, patient experienced the following side effects: blood urea increased, brain scan abnormal, confusional state, gait disturbance, haemoglobin abnormal, hydrocephalus , hypokalaemia, hyponatraemia, incontinence. Gliadel dosage: 7.7 MG PER WAFER ONCE IV. During the same period patient was treated with KEPPRA, DECADRON, ZANTAC, TERAZOSIN, DIAMOX SEQUELE. Patient was hospitalized. Patient recovered.

Gliadel Side Effects Report #5484455-X
Gliadel side effect was reported by a Physician from UNITED STATES on Oct 03, 2007. Female patient was diagnosed with glioblastoma multiforme and was treated with Gliadel. After drug was administered, patient experienced the following side effects: arachnoiditis, cerebral hygroma, hydrocephalus , hyponatraemia, intracranial hypotension, meningitis , postoperative wound infection, pyrexia. Gliadel dosage: unknown. Patient recovered.

Gliadel Side Effects Report #5490043-1
Gliadel side effect was reported by a Physician from UNITED STATES on June 27, 2007. Female patient was diagnosed with glioblastoma multiforme and was treated with Gliadel. After drug was administered, patient experienced the following side effects: arachnoiditis, cerebral hygroma, hydrocephalus , hyponatraemia, intracranial hypotension, meningitis , postoperative wound infection. Gliadel dosage: unknown. Patient recovered.

Gliadel Side Effects Report #4712795-8
Gliadel side effect was reported by a Consumer or non-health professional from UNITED STATES on July 11, 2005. Female patient, weighting 197.3 lb, was diagnosed with glioblastoma multiforme and was treated with Gliadel. After drug was administered, patient experienced the following side effects: convulsion, headache , hyponatraemia, hypotension, somnolence, urosepsis. Gliadel dosage: 7.7 MG PER WAFER - MAX OF 8. During the same period patient was treated with DILANTIN, NEURONTIN, CARDIZEM, LISINOPRIL, DECADRON. Patient was hospitalized. Patient recovered.

Gliadel Side Effects Report #5108262-2
Gliadel side effect was reported by a Health Professional from UNITED STATES on Sept 14, 2006. Male patient, weighting 186.3 lb, was diagnosed with glioblastoma multiforme and was treated with Gliadel. After drug was administered, patient experienced the following side effects: deep vein thrombosis , dermatitis herpetiformis, dysphagia, hyponatraemia, inflammation, mental status changes, nuclear magnetic resonance imaging brain abnormal, pyrexia. Gliadel dosage: 7.7 MG PER WAFER ONCE IV. During the same period patient was treated with CARBATROL, ZANTAC, HYDROCHLOROTHIAZDE, CHLORIDE, DECADRON. Patient was hospitalized. Patient recovered.