Grtpa and atrial fibrillation Patient Reports February 10, 2010

Grtpa Side Effects Report #5268377-5
Grtpa side effect was reported by a Consumer or non-health professional from JAPAN on Mar 06, 2007. Male patient, 87 years of age, was diagnosed with cerebral artery embolism, atrial fibrillation  and was treated with Grtpa. After drug was administered, patient experienced the following side effects: atrial fibrillation , blood alkaline phosphatase increased, cerebral artery occlusion, cerebral thrombosis, haemorrhagic cerebral infarction, multi-organ failure, platelet count decreased, renal impairment, respiratory disorder. Grtpa dosage: 2.9 ML, INTRAVENOUS, 26.1 ML, IV DRIP. During the same period patient was treated with HEPARIN, RADICUT, FAMOTIDINE, GLYCERIN. Patient died on 12/02/2006.

Grtpa Side Effects Report #5252853-5
Grtpa side effect was reported by a Health Professional from JAPAN on Feb 21, 2007. Male patient, 86 years of age, was diagnosed with cerebral artery embolism and was treated with Grtpa. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, arrhythmia , aspartate aminotransferase increased, atrial fibrillation , blood lactate dehydrogenase increased, cardiac failure, condition aggravated, hepatic function abnormal, platelet count decreased. Grtpa dosage: 29 ML, SINGLE, INTRAVENOUS. Patient died on 10/28/2006.

Grtpa Side Effects Report #5175142-6
Grtpa side effect was reported by a Health Professional from JAPAN on Nov 27, 2006. Male patient, 86 years of age, was diagnosed with cerebral artery embolism and was treated with Grtpa. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, arrhythmia , aspartate aminotransferase increased, atrial fibrillation , blood lactate dehydrogenase increased, condition aggravated, hepatic function abnormal, tachycardia. Grtpa dosage: 29 ML, SINGLE, INTRAVENOUS. Patient died on 10/28/2006.