Grtpa and brain oedema Patient Reports February 09, 2010

Grtpa Side Effects Report #5236367-4
Grtpa side effect was reported by a Health Professional from JAPAN on Feb 01, 2007. Male patient, 78 years of age, was diagnosed with ischaemic stroke and was treated with Grtpa. After drug was administered, patient experienced the following side effects: blood pressure decreased, brain herniation, brain oedema, cardiac arrest , mydriasis, respiratory disorder. Grtpa dosage: 30 ML, SINGLE, INTRAVENOUS. During the same period patient was treated with MANNITOL, DECADRON, DOPAMINE, RADICUT. Patient died on 03/03/2006.

Grtpa Side Effects Report #5258251-2
Grtpa side effect was reported by a Health Professional from JAPAN on Feb 28, 2007. Female patient, 80 years of age, was diagnosed with cerebral infarction and was treated with Grtpa. After drug was administered, patient experienced the following side effects: brain oedema, haematocrit decreased, haemoglobin decreased, international normalised ratio decreased, no therapeutic response, platelet count decreased, red blood cell count decreased. Grtpa dosage: 30.1 MG, SINGLE, INTRAVENOUS. During the same period patient was treated with WARFARIN, RADICUT, ZANTAC. Patient died on 02/15/2007.

Grtpa Side Effects Report #4974749-6
Grtpa side effect was reported by a Physician from JAPAN on Apr 03, 2006. Male patient, 78 years of age, was diagnosed with cerebral infarction and was treated with Grtpa. After drug was administered, patient experienced the following side effects: blood pressure decreased, brain herniation, brain oedema, cardiac arrest , mydriasis, respiration abnormal. Grtpa dosage: 30 ML, SINGLE, INTRAVENOUS. During the same period patient was treated with MANNITOL, DECADRON, DOPAMINE, RADICUT. Patient died on 03/03/2006.

Grtpa Side Effects Report #5080665-4
Grtpa side effect was reported by a Physician from JAPAN on Aug 02, 2006. Male patient, 76 years of age, was diagnosed with cerebral artery embolism and was treated with Grtpa. After drug was administered, patient experienced the following side effects: blood pressure decreased, blood pressure increased, brain herniation, brain oedema, mydriasis, pupillary reflex impaired, pupils unequal, respiratory failure. Grtpa dosage: 33.1 ML, SINGLE, INTRAVENOUS. During the same period patient was treated with NICARDIPINE HYDROCHLORIDE. Patient died.


Grtpa Side Effects Report #5082960-1
Grtpa side effect was reported by a Health Professional from JAPAN on Aug 07, 2006. Male patient, 76 years of age, was diagnosed with cerebral artery embolism and was treated with Grtpa. After drug was administered, patient experienced the following side effects: blood pressure increased, brain herniation, brain oedema, depressed level of consciousness, mydriasis, pupillary light reflex tests abnormal, pupils unequal, respiratory failure, urine output increased. Grtpa dosage: 33.1 ML, SINGLE, INTRAVENOUS. During the same period patient was treated with NICARDIPINE HYDROCHLORIDE, FAMOTIDINE, DIAZEPAM, RADICUT, GLYCEOL. Patient died.

Grtpa Side Effects Report #5192693-9
Grtpa side effect was reported by a Health Professional from JAPAN on Dec 18, 2006. Male patient, 76 years of age, was diagnosed with cerebral artery embolism and was treated with Grtpa. After drug was administered, patient experienced the following side effects: blood pressure increased, brain herniation, brain oedema, carotid artery occlusion, cerebral artery embolism, cerebral infarction, depressed level of consciousness, mydriasis, pupillary reflex impaired. Grtpa dosage: 33.1 ML, SINGLE, INTRAVENOUS. During the same period patient was treated with NICARDIPINE HYDROCHLORIDE, FAMOTIDINE, DIAZEPAM, RADICUT, GLYCEOL. Patient died.

Grtpa Side Effects Report #4974751-4
Grtpa side effect was reported by a Health Professional from JAPAN on Apr 03, 2006. Male patient, 71 years of age, was diagnosed with cerebral artery embolism and was treated with Grtpa. After drug was administered, patient experienced the following side effects: blood glucose increased, blood pressure increased, brain oedema, condition aggravated, haemorrhagic cerebral infarction, renal failure acute, renal impairment, shock, subarachnoid haemorrhage. Grtpa dosage: 41.4 MG, INTRAVENOUS. During the same period patient was treated with ADALAT, DILTIAZEM HYDROCHLORIDE, LACTEC, GLYCERIN, FRUCTOSE, HUMULIN R, LASIX, VITAMIN D. Patient died on 01/14/2006.

Grtpa Side Effects Report #5201090-9
Grtpa side effect was reported by a Health Professional from JAPAN on Dec 27, 2006. Male patient, 65 years of age, was diagnosed with cerebral artery embolism and was treated with Grtpa. After drug was administered, patient experienced the following side effects: brain herniation, brain oedema, cerebral infarction, haemorrhagic cerebral infarction, respiratory failure. Grtpa dosage: 31.9 ML, SINGLE, INTRAVENOUS. During the same period patient was treated with NICARDIPINE HYDROCHLORIDE. Patient died.

Grtpa Side Effects Report #5203418-2
Grtpa side effect was reported by a Health Professional from JAPAN on Dec 27, 2006. Male patient, 65 years of age, was diagnosed with cerebral artery embolism and was treated with Grtpa. After drug was administered, patient experienced the following side effects: brain herniation, brain oedema, haemorrhagic cerebral infarction, respiratory failure. Grtpa dosage: 31.9 ML, SINGLE, INTRAVENOUS. During the same period patient was treated with NICARDIPINE HYDROCHLORIDE. Patient died on 04/01/2006.


Grtpa Side Effects Report #5223288-6
Grtpa side effect was reported by a Health Professional from JAPAN on Jan 19, 2007. Male patient, 65 years of age, was diagnosed with cerebral artery embolism and was treated with Grtpa. After drug was administered, patient experienced the following side effects: brain herniation, brain oedema, depressed level of consciousness, haemorrhagic cerebral infarction, respiratory failure. Grtpa dosage: 31.9 ML, SINGLE, INTRAVENOUS. During the same period patient was treated with NICARDIPINE HYDROCHLORIDE. Patient died on 04/01/2006.

Grtpa Side Effects Report #4950337-2
Grtpa side effect was reported by a Physician from JAPAN on Mar 06, 2006. Male patient, 78 years of age, was treated with Grtpa. After drug was administered, patient experienced the following side effects: brain herniation, brain oedema. Grtpa dosage: unknown. Patient recovered.