Irinotecan and condition aggravated Patient Reports February 10, 2010

Irinotecan Side Effects Report #5148077-2
Irinotecan side effect was reported by a Physician from JAPAN on Oct 24, 2006. Female patient, 80 years of age, was diagnosed with rectal cancer recurrent and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: condition aggravated, disseminated intravascular coagulation, pancytopenia, pneumonia , respiratory disorder, staphylococcal infection . Irinotecan dosage: 140 MG (1 IN 1 WK), INTRAVENOUS. During the same period patient was treated with LEUCOVORIN CALCIUM. Patient died on 11/15/2005.

Irinotecan Side Effects Report #5945728-7
Irinotecan side effect was reported by a Health Professional from UNITED KINGDOM on Oct 21, 2008. Female patient, 77 years of age, was diagnosed with rectal cancer metastatic and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: condition aggravated, neuropathy peripheral. Irinotecan dosage: 350 MG/M**2; IV. Patient recovered.

Irinotecan Side Effects Report #4830322-1
Irinotecan side effect was reported by a Physician from JAPAN on Nov 02, 2005. Male patient, 62 years of age, was diagnosed with rectal cancer metastatic and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: condition aggravated, interstitial lung disease, malignant neoplasm progression, metastases to lung, rectal cancer, tumour marker increased. Irinotecan dosage: 60-100 MG (EVERY TWO WEEKS), INTRAVENOUS. During the same period patient was treated with TEGAFUR. Patient recovered.

Irinotecan Side Effects Report #4656690-1
Irinotecan side effect was reported by a Consumer or non-health professional from on Apr 27, 2005. Male patient, 73 years of age, was diagnosed with rectal cancer and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: anorexia, blood pressure decreased, condition aggravated, disseminated intravascular coagulation, escherichia infection, malaise, metastasis, neoplasm progression, pancytopenia. Irinotecan dosage: 100 MG, INTRAVENOUS. During the same period patient was treated with ZANTAC, FLUOROURACIL, CALCIUM LEVOFOLINATE. Patient was hospitalized and became disabled. Patient died on 02/26/2005.


Irinotecan Side Effects Report #4704326-3
Irinotecan side effect was reported by a Consumer or non-health professional from on Apr 27, 2005. Male patient, 73 years of age, was diagnosed with rectal cancer and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: alpha haemolytic streptococcal infection, anorexia, blood pressure decreased, condition aggravated, disseminated intravascular coagulation, escherichia infection, malaise, pancytopenia, sepsis . Irinotecan dosage: 100 MG INTRAVENOUS. During the same period patient was treated with FLUOROURACIL, CALCIUM FOLINATE. Patient was hospitalized and became disabled. Patient died on 02/26/2005.

Irinotecan Side Effects Report #4776561-X
Irinotecan side effect was reported by a Physician from JAPAN on Sept 02, 2005. Male patient, 42 years of age, weighting 105.8 lb, was diagnosed with rectal cancer and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: anorexia, bone marrow depression, coagulopathy, condition aggravated, dehydration, diarrhoea, disseminated intravascular coagulation, haemorrhagic diathesis, malaise. Irinotecan dosage: 80 MG (1 D), INTRAVENOUS; 60 MG (1 D), INTRAVENOUS. During the same period patient was treated with IRINOTECAN HYDROCHLORIDE, FLUOROURACIL, STRONG, CALCIUM LEVOFOLINATE, CALCIUM LEVOFOLINATE. Patient was hospitalized. Patient died on 08/29/2005.

Irinotecan Side Effects Report #4590068-4
Irinotecan side effect was reported by a Physician from on Feb 07, 2005. Male patient was diagnosed with rectal cancer and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: bone marrow depression, condition aggravated, hepatic failure, rectal cancer. Irinotecan dosage: (100 MG, INTERMITTENT), INTRAVENOUS. During the same period patient was treated with TEGAFUR. Patient died on 01/25/2005.

Irinotecan Side Effects Report #4645398-4
Irinotecan side effect was reported by a Physician from on Apr 11, 2005. Male patient was diagnosed with rectal cancer and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: bone marrow depression, condition aggravated, hepatic failure, rectal cancer. Irinotecan dosage: (100 MG, INTERMITTENT)-, INTRAVENOUS. During the same period patient was treated with TEGAFUR. Patient died on 01/25/2005.

Irinotecan Side Effects Report #4693777-1
Irinotecan side effect was reported by a Physician from on June 03, 2005. Female patient, 68 years of age, weighting 81.57 lb, was diagnosed with ovarian cancer and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: anorexia, bone marrow depression, condition aggravated, cyanosis, disease progression, disease recurrence, infection , interstitial lung disease, malaise. Irinotecan dosage: unknown. During the same period patient was treated with GRAN, ETOPOSIDE, TAXOTERE. Patient was hospitalized. Patient died on 03/03/2005.


Irinotecan Side Effects Report #5117954-0
Irinotecan side effect was reported by a Physician from JAPAN on Sept 13, 2006. Female patient, 67 years of age, weighting 81.57 lb, was diagnosed with ovarian cancer and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: anorexia, bone marrow failure, condition aggravated, infection , interstitial lung disease, malaise, malnutrition, metastases to spleen. Irinotecan dosage: unknown. During the same period patient was treated with NEUPOGEN, ETOPOSIDE, TAXOTERE. Patient was hospitalized. Patient died on 03/03/2005.

Irinotecan Side Effects Report #4934730-X
Irinotecan side effect was reported by a Physician from JAPAN on Feb 17, 2006. Male patient, 72 years of age, was diagnosed with non-small cell lung cancer and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, condition aggravated, diffuse alveolar damage, interstitial lung disease, nasopharyngitis. Irinotecan dosage: unknown. During the same period patient was treated with CISPLATIN. Patient died.

Irinotecan Side Effects Report #5051762-4
Irinotecan side effect was reported by a Consumer or non-health professional from UNITED STATES on July 13, 2006. Female patient, weighting 116.4 lb, was diagnosed with glioblastoma multiforme and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: condition aggravated, culture wound positive, erythema, malignant neoplasm progression, post procedural complication, serratia infection. Irinotecan dosage: 325MG/M2 DAY 1,8,22,29 IV. During the same period patient was treated with TEMODAR, DILANTIN, NEXIUM, DEXAMETHASONE, SENOKOT, ENDOCET. Patient was hospitalized. Patient recovered.

Irinotecan Side Effects Report #5427034-2
Irinotecan side effect was reported by a Consumer or non-health professional from UNITED STATES on Aug 24, 2007. Male patient, weighting 269.0 lb, was diagnosed with glioblastoma multiforme and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: blood alkaline phosphatase increased, condition aggravated, confusional state, convulsion, disease progression, haemoglobin decreased, mental status changes. Irinotecan dosage: 325MG/M2 DAY 1, 8, 22, 29 IV. During the same period patient was treated with TEMODAR, DILANTIN, PEPCID, CLORAZEPATE, DECADRON. Patient was hospitalized. Patient recovered.

Irinotecan Side Effects Report #5017894-1
Irinotecan side effect was reported by a Consumer or non-health professional from UNITED STATES on June 02, 2006. Female patient, weighting 125.9 lb, was diagnosed with glioblastoma multiforme and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: aphasia , brain herniation, computerised tomogram abnormal, condition aggravated, depressed level of consciousness, fatigue, pyrexia, respiratory arrest, somnolence. Irinotecan dosage: 325MG/M2 DAY 1, 8, 22, 29 IV. During the same period patient was treated with TEMODAR, DILANTIN, PEPCID, DECADRON, FLORINEF, MICARDIS, HUMALOG, LANTUS. Patient died on 05/31/2006.


Irinotecan Side Effects Report #4847607-5
Irinotecan side effect was reported by a Physician from JAPAN on Nov 22, 2005. Male patient, 79 years of age, was diagnosed with gastric cancer recurrent and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: condition aggravated, interstitial lung disease. Irinotecan dosage: unknown. During the same period patient was treated with TEGAFUR, ALLEGRA, LIVOSTIN. Patient was hospitalized. Patient recovered.

Irinotecan Side Effects Report #4603275-9
Irinotecan side effect was reported by a Physician from on Feb 24, 2005. Male patient, 70 years of age, was diagnosed with colorectal cancer recurrent and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: condition aggravated, interstitial lung disease. Irinotecan dosage: 120 MG/M2, INTRAVENOUS. During the same period patient was treated with TEGAFUR. Patient died on 09/05/2004.

Irinotecan Side Effects Report #4645749-0
Irinotecan side effect was reported by a Physician from on Apr 11, 2005. Male patient, 70 years of age, weighting 141.3 lb, was diagnosed with colorectal cancer recurrent and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, anorexia, condition aggravated, interstitial lung disease, nausea , pelvic abscess. Irinotecan dosage: unknown. During the same period patient was treated with TEGAFUR URACIL, TEGAFUR GIMERACIL, TEGAFUR GIMERACIL. Patient died on 09/05/2004.

Irinotecan Side Effects Report #4708418-4
Irinotecan side effect was reported by a Physician from UNITED STATES on June 21, 2005. Male patient, 95 years of age, was diagnosed with colorectal cancer metastatic and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: anorexia, blood creatine increased, blood culture positive, blood urea increased, condition aggravated, dehydration, diabetes mellitus, diarrhoea, dysphagia. Irinotecan dosage: 300 MG/M2 (300 MG/M2, CYCLIC), INTRAVENOUS. Patient was hospitalized. Patient died on 06/07/2005.

Irinotecan Side Effects Report #4747201-0
Irinotecan side effect was reported by a Physician from UNITED STATES on Aug 02, 2005. Male patient, 95 years of age, was diagnosed with colorectal cancer metastatic and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: anorexia, bacteria blood identified, blood urea increased, colorectal cancer metastatic, condition aggravated, dehydration, diabetes mellitus non-insulin-dependent, diarrhoea, dysphagia. Irinotecan dosage: 300 MG/M2 (300 MG/M2, CYCLIC), INTRAVENOUS. Patient was hospitalized. Patient died on 06/07/2005.


Irinotecan Side Effects Report #5290947-9
Irinotecan side effect was reported by a Consumer or non-health professional from FRANCE on Mar 30, 2007. Male patient, weighting 154.3 lb, was diagnosed with colorectal cancer metastatic and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: aphasia , colorectal cancer metastatic, condition aggravated, depressed level of consciousness, febrile bone marrow aplasia, febrile neutropenia, infection , platelet count decreased. Irinotecan dosage: unknown. During the same period patient was treated with FLUOROURACIL, CALCIUM FOLINATE, BEVACIZUMAB. Patient died on 01/01/2007.

Irinotecan Side Effects Report #5127462-9
Irinotecan side effect was reported by a Physician from JAPAN on Sept 27, 2006. Female patient, 67 years of age, was diagnosed with colon cancer metastatic and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: blood bilirubin increased, blood creatinine increased, condition aggravated, diarrhoea, dyspnoea, haemoglobin decreased, hepatorenal failure, hyperthermia. Irinotecan dosage: 160 MG, INTRAVENOUS (SEE IMAGE). Patient was hospitalized. Patient died on 05/18/2004.

Irinotecan Side Effects Report #5947972-1
Irinotecan side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on Oct 22, 2008. Male patient, 63 years of age, weighting 176.4 lb, was diagnosed with colon cancer metastatic and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: condition aggravated, neuropathy peripheral. Irinotecan dosage: 350 MG/M2 IV. During the same period patient was treated with OXALIPLATIN, CAPECITABINE. Patient recovered.

Irinotecan Side Effects Report #6000667-0
Irinotecan side effect was reported by a Health Professional from UNITED KINGDOM on Oct 21, 2008. Male patient, 63 years of age, was diagnosed with colon cancer metastatic and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: condition aggravated, neuropathy peripheral. Irinotecan dosage: 350 MG/M**2; IV. During the same period patient was treated with OXALIPLATIN, CAPECITABINE. Patient recovered.

Irinotecan Side Effects Report #5697944-X
Irinotecan side effect was reported by a Health Professional from UNITED STATES on Apr 04, 2008. Male patient, weighting 261.5 lb, was diagnosed with colon cancer metastatic and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: atrial fibrillation , condition aggravated, dyspnoea, tachycardia. Irinotecan dosage: 432 MG IV. During the same period patient was treated with CETUXIMAB, ASPIRIN, COLACE, LASIX, GLIPIZIDE, HYDRALAZINE, LIPITOR. Patient was hospitalized. Patient recovered.


Irinotecan Side Effects Report #5034327-X
Irinotecan side effect was reported by a Physician from JAPAN on June 07, 2006. Male patient, 77 years of age, was diagnosed with colon cancer and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: abnormal behaviour, abnormal faeces, acute respiratory distress syndrome, anorexia, blood pressure immeasurable, cancer pain, cardiac arrest , condition aggravated, diarrhoea. Irinotecan dosage: 100 MG (100 MG, DAILY), INTRAVENOUS. During the same period patient was treated with TEGAFUR, MUCOSTA, MAGNESIUM OXIDE, MORPHINE, FENTANYL, MOBIC, PRIMPERAN, DOGMATYL. Patient died on 04/07/2006.

Irinotecan Side Effects Report #4579243-2
Irinotecan side effect was reported by a Physician from on Feb 08, 2005. Male patient, 65 years of age, weighting 163.1 lb, was diagnosed with colon cancer and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: coagulopathy, condition aggravated, diarrhoea, haematoma, international normalised ratio increased, prothrombin time prolonged, renal failure. Irinotecan dosage: unknown. During the same period patient was treated with FLUOROURACIL, FOLINIC ACID, ATROPINE SULPHATE, MARCUMAR, OPIUM TINCTURE. Patient was hospitalized. Patient recovered.

Irinotecan Side Effects Report #4588558-3
Irinotecan side effect was reported by a Physician from on Feb 15, 2005. Male patient, 65 years of age, weighting 163.1 lb, was diagnosed with colon cancer and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: coagulopathy, condition aggravated, diarrhoea, haematoma, renal failure. Irinotecan dosage: unknown. During the same period patient was treated with FLUOROURACIL, FOLINIC ACID, MARCUMAR, OPIUM TINCTURE, ATROPINE SULPHATE. Patient was hospitalized. Patient recovered.

Irinotecan Side Effects Report #4620192-9
Irinotecan side effect was reported by a Physician from on Mar 21, 2005. Male patient, 65 years of age, weighting 163.1 lb, was diagnosed with colon cancer and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: blood creatinine increased, coagulopathy, condition aggravated, diarrhoea, frequent bowel movements, haematoma, international normalised ratio increased, prothrombin time prolonged, renal failure. Irinotecan dosage: unknown. During the same period patient was treated with FLUOROURACIL, FOLINIC ACID, ATROPINE SULPHATE, MARCUMAR, OPIUM TINCTURE. Patient was hospitalized. Patient recovered.

Irinotecan Side Effects Report #4588558-3
Irinotecan side effect was reported by a Physician from on Feb 15, 2005. Male patient, 65 years of age, weighting 163.1 lb, was diagnosed with colon cancer and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: coagulopathy, condition aggravated, diarrhoea, haematoma, renal failure. Irinotecan dosage: unknown. During the same period patient was treated with FLUOROURACIL, LEUCOVORIN CALCIUM, MARCUMAR, OPIUM TINCTURE, ATROPINE SULPHATE. Patient was hospitalized. Patient recovered.


Irinotecan Side Effects Report #4754885-X
Irinotecan side effect was reported by a Physician from GERMANY on Aug 26, 2005. Male patient, 65 years of age, weighting 163.1 lb, was diagnosed with colon cancer and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: abnormal faeces, blood creatinine increased, coagulopathy, condition aggravated, diarrhoea, haematoma, nausea , renal failure. Irinotecan dosage: unknown. During the same period patient was treated with FLUOROURACIL, FOLINIC ACID, ATROPINE SULPHATE, OPIUM TINCTURE, KALITRANS. Patient was hospitalized. Patient recovered.

Irinotecan Side Effects Report #4603087-6
Irinotecan side effect was reported by a Physician from on Feb 22, 2005. Male patient, 78 years of age, weighting 141.1 lb, was treated with Irinotecan. After drug was administered, patient experienced the following side effects: blood lactate dehydrogenase increased, condition aggravated, depressed level of consciousness, interstitial lung disease, pneumonitis, respiratory failure. Irinotecan dosage: 60 MG (INTERMITTENT), INTRAVENOUS. During the same period patient was treated with CISPLATIN. Patient died on 01/16/2005.

Irinotecan Side Effects Report #4648778-6
Irinotecan side effect was reported by a Physician from on Apr 14, 2005. Male patient, 78 years of age, weighting 141.1 lb, was treated with Irinotecan. After drug was administered, patient experienced the following side effects: blood lactate dehydrogenase increased, condition aggravated, depressed level of consciousness, interstitial lung disease, lung neoplasm malignant, pneumonitis, refusal of treatment by patient, respiratory failure. Irinotecan dosage: 60 MG (INTERMITTENT), INTRAVENOUS. During the same period patient was treated with CISPLATIN, HERBAL PREPARATION. Patient died on 01/16/2005.

Irinotecan Side Effects Report #5133778-2
Irinotecan side effect was reported by a Health Professional from JAPAN on May 19, 1999. Male patient, 69 years of age, was treated with Irinotecan. After drug was administered, patient experienced the following side effects: condition aggravated, contraindication to medical treatment, depressed level of consciousness, grand mal convulsion, hepatic failure, hypokalaemia, leukopenia, malignant neoplasm progression, metastases to liver. Irinotecan dosage: 100 MG/M*2, INTRAVENOUS. During the same period patient was treated with AMINO ACIDS, CEFOZOPRAN HYDROCHLORIDE, CLINDAMYCIN PHOSPHATE, HANGE, LENORGRASTIM, METOCLOPRAMIDE, PHENYTOIN, VALPROATE. Patient died on 04/04/1999.