Irinotecan and sepsis Patient Reports February 10, 2010

Irinotecan Side Effects Report #5154626-0
Irinotecan side effect was reported by a Physician from GERMANY on Mar 28, 1998. Male patient, 67 years of age, was diagnosed with rectal cancer metastatic and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: atrial fibrillation , leukopenia, malignant neoplasm progression, rectal cancer metastatic, sepsis , thrombocytopenia. Irinotecan dosage: 530 MG, INTRAVENOUS. During the same period patient was treated with ALLOPURINOL, DEXABENE, ZANTIC, ZOFRAN. Patient died on 03/25/1998.

Irinotecan Side Effects Report #4561286-6
Irinotecan side effect was reported by a Health Professional from on Jan 10, 2005. Female patient, 86 years of age, weighting 147.0 lb, was diagnosed with rectal cancer and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: asthenia, eating disorder , fatigue, fluid intake reduced, neutropenia, proctalgia, radiation injury, sepsis . Irinotecan dosage: 30 MG/M2 (WEEKLY X 6 WEEKS), INTRAVENOUS. During the same period patient was treated with CAPECITABINE. Patient was hospitalized. Patient recovered.

Irinotecan Side Effects Report #5837221-7
Irinotecan side effect was reported by a Physician from JAPAN on Aug 04, 2008. Male patient, 58 years of age, was diagnosed with rectal cancer and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: necrotising fasciitis, sepsis . Irinotecan dosage: unknown. During the same period patient was treated with LEUCOVORIN CALCIUM, FLUOROURACIL, ELPLAT, AVASTIN. Patient was hospitalized. Patient recovered.

Irinotecan Side Effects Report #5348424-2
Irinotecan side effect was reported by a Consumer or non-health professional from JAPAN on May 25, 2007. Male patient was diagnosed with rectal cancer, hypertension, diabetes mellitus and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: anorexia, blood bilirubin increased, diarrhoea, disseminated intravascular coagulation, nausea , pyrexia, renal impairment, sepsis . Irinotecan dosage: DAILY DOSE:150MG/M2. During the same period patient was treated with CALCIUM FOLINATE, FLUOROURACIL, NORVASC, ALMARL, AMARYL, OLMETEC, GLUCOBAY. Patient was hospitalized. Patient recovered.


Irinotecan Side Effects Report #6085592-1
Irinotecan side effect was reported by a Physician from JAPAN on Feb 10, 2009. Female patient was diagnosed with rectal cancer and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: pneumonia , sepsis . Irinotecan dosage: 322 MG, EVERY 2 WEEKS. During the same period patient was treated with SUNITINIB MALATE, FLUOROURACIL, DOMPERIDONE, RINGER LACTATE, RINGER LACTATE. Patient was hospitalized. Patient recovered.

Irinotecan Side Effects Report #6098929-4
Irinotecan side effect was reported by a Physician from JAPAN on Feb 18, 2009. Female patient was diagnosed with rectal cancer and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: pneumonia , sepsis . Irinotecan dosage: 322 MG, EVERY 2 WEEKS. During the same period patient was treated with SUNITINIB MALATE, FLUOROURACIL, DOMPERIDONE, LACTATED RINGER, LACTATED RINGER. Patient was hospitalized. Patient recovered.

Irinotecan Side Effects Report #6133860-7
Irinotecan side effect was reported by a Physician from JAPAN on Mar 17, 2009. Female patient was diagnosed with rectal cancer and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: pneumonia , sepsis . Irinotecan dosage: 322 MG, EVERY 2 WEEKS. During the same period patient was treated with SUNITINIB MALATE, FLUOROURACIL, DOMPERIDONE, LACTATED RINGER, LACTATED RINGER. Patient was hospitalized. Patient recovered.

Irinotecan Side Effects Report #4862633-8
Irinotecan side effect was reported by a Health Professional from UNITED STATES on Dec 19, 2005. Female patient, weighting 158.4 lb, was diagnosed with pancreatic carcinoma metastatic and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: dyspnoea, hypotension, orthopnoea, oxygen saturation abnormal, pleural effusion, renal failure acute, sepsis , therapeutic agent toxicity. Irinotecan dosage: 65MG/M2 Q 21 DAYS IV DRIP. During the same period patient was treated with DOCETAXEL. Patient was hospitalized. Patient died on 12/08/2005.

Irinotecan Side Effects Report #5013898-3
Irinotecan side effect was reported by a Consumer or non-health professional from JAPAN on May 12, 2006. Female patient, 72 years of age, weighting 68.34 lb, was diagnosed with pancreatic carcinoma and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: bone marrow failure, disseminated intravascular coagulation, hepatic steatosis, malignant neoplasm progression, pancreatic carcinoma metastatic, sepsis . Irinotecan dosage: unknown. During the same period patient was treated with PN TWIN, ELEMENMIC, INTRALIPID, DECADRON SRC. Patient was hospitalized. Patient recovered.


Irinotecan Side Effects Report #4859961-9
Irinotecan side effect was reported by a Physician from JAPAN on Nov 30, 2005. Female patient, 51 years of age, weighting 97.00 lb, was diagnosed with ovarian cancer and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: bone marrow failure, disseminated intravascular coagulation, hepatic failure, intestinal perforation, pancytopenia, sepsis . Irinotecan dosage: 160 MG (160 MG, ) INTRAVENOUS. During the same period patient was treated with MITOMYCIN. Patient was hospitalized. Patient recovered.

Irinotecan Side Effects Report #5915433-1
Irinotecan side effect was reported by a Health Professional from JAPAN on Sept 29, 2008. Male patient, 79 years of age, was diagnosed with non-small cell lung cancer recurrent and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: diarrhoea, sepsis . Irinotecan dosage: unknown. During the same period patient was treated with CARBOPLATIN. Patient died on 09/05/2008.

Irinotecan Side Effects Report #5939241-0
Irinotecan side effect was reported by a Health Professional from JAPAN on Oct 22, 2008. Male patient, 79 years of age, was diagnosed with non-small cell lung cancer recurrent and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: diarrhoea, leukopenia, sepsis . Irinotecan dosage: unknown. During the same period patient was treated with CARBOPLATIN. Patient died on 09/05/2008.

Irinotecan Side Effects Report #5465560-0
Irinotecan side effect was reported by a Consumer or non-health professional from FRANCE on Oct 26, 1993. Female patient was diagnosed with non-hodgkin's lymphoma and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: deafness, febrile neutropenia, sepsis . Irinotecan dosage: DAILY DOSE:580MG. During the same period patient was treated with PREDNIMUSTINE, AMIKACIN, DIPHENOXYLATE, ETOPOSIDE, LOPERAMIDE, MITOGUAZONE. Patient recovered.

Irinotecan Side Effects Report #4765461-7
Irinotecan side effect was reported by a Physician from JAPAN on Aug 19, 2005. Male patient, 74 years of age, weighting 176.6 lb, was diagnosed with lung neoplasm malignant and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, bone marrow toxicity, multi-organ failure, neutropenia, pneumonia , respiratory failure, sepsis , systemic inflammatory response syndrome. Irinotecan dosage: 60 MG/M2 (INTERMITTENT), INTRAVENOUS. During the same period patient was treated with CISPLATIN, BETAMETHASONE, FAMOTIDINE, LASIX. Patient died on 07/22/2005.


Irinotecan Side Effects Report #4758091-4
Irinotecan side effect was reported by a Physician from JAPAN on Aug 10, 2005. Male patient was diagnosed with lung neoplasm malignant and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: bone marrow toxicity, respiratory failure, sepsis , systemic inflammatory response syndrome. Irinotecan dosage: 60 MG/M2 (INTERMITTENT), INTRAVENOUS. During the same period patient was treated with CISPLATIN. Patient died on 07/22/2005.

Irinotecan Side Effects Report #5909435-9
Irinotecan side effect was reported by a Health Professional from JAPAN on Sept 24, 2008. Male patient, 79 years of age, was diagnosed with lung adenocarcinoma recurrent and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: diarrhoea, sepsis . Irinotecan dosage: unknown. During the same period patient was treated with CARBOPLATIN. Patient died.

Irinotecan Side Effects Report #5409600-3
Irinotecan side effect was reported by a Consumer or non-health professional from UNITED STATES on Aug 07, 2007. Male patient, weighting 153.4 lb, was diagnosed with glioblastoma multiforme and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: confusional state, deep vein thrombosis , neutropenia, pulmonary embolism , pyrexia, sepsis , vomiting. Irinotecan dosage: 125MG/M2 DAY 1, 8, 22, 29 IV. During the same period patient was treated with TEMODAR, VERAPAMIL, ASPIRIN, DEXAMETHASONE, DEPAKOTE, KLONOPIN. Patient was hospitalized. Patient recovered.

Irinotecan Side Effects Report #5895164-7
Irinotecan side effect was reported by a Consumer or non-health professional from UNITED STATES on Sept 23, 2008. Male patient, weighting 218.3 lb, was diagnosed with glioblastoma multiforme and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: asthenia, diarrhoea, hypotension, leukopenia, renal failure acute, sepsis , tachycardia. Irinotecan dosage: 125MG/M2, 80MG/M2 DAY 1, 8 IV. During the same period patient was treated with TEMODAR, COUMADIN, LOTREL, LASIX, TOPROL, DECADRON, LIPITOR. Patient died on 08/02/2007.

Irinotecan Side Effects Report #5905520-6
Irinotecan side effect was reported by a Consumer or non-health professional from UNITED STATES on Oct 01, 2008. Male patient, weighting 218.3 lb, was diagnosed with glioblastoma multiforme and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: asthenia, diarrhoea, hypotension, leukopenia, renal failure acute, sepsis , tachycardia. Irinotecan dosage: 125MG/M2, 80MG/M2 DAY 1, 8 IV. During the same period patient was treated with IRINOTECAN HYDROCHLORIDE, TEMODAR, COUMADIN, LOTREL, LASIX, TOPROL, DECADRON, LIPITOR. Patient died on 08/02/2007.


Irinotecan Side Effects Report #5947851-X
Irinotecan side effect was reported by a Consumer or non-health professional from UNITED STATES on Nov 10, 2008. Male patient, weighting 218.3 lb, was diagnosed with glioblastoma multiforme and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: asthenia, hypotension, renal failure acute, sepsis , tachycardia. Irinotecan dosage: 125MG/M2, 80MG/M2 DAY 1, 8 IV. During the same period patient was treated with IRINOTECAN HYDROCHLORIDE, TEMODAR. Patient died on 08/02/2007.

Irinotecan Side Effects Report #4925254-4
Irinotecan side effect was reported by a Consumer or non-health professional from UNITED STATES on Feb 23, 2006. Female patient, weighting 185.0 lb, was diagnosed with glioblastoma multiforme and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: central nervous system infection, convulsion, glioblastoma multiforme, pyrexia, recurrent cancer, sepsis , staphylococcal infection . Irinotecan dosage: 736 MG. During the same period patient was treated with TEMOZOLOMIDE. Patient was hospitalized. Patient recovered.

Irinotecan Side Effects Report #4633207-9
Irinotecan side effect was reported by a Physician from on Mar 29, 2005. Male patient, 67 years of age, weighting 152.1 lb, was diagnosed with gastric cancer and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: dehydration, diarrhoea, multi-organ failure, renal failure, sepsis . Irinotecan dosage: 80MG/M2 (1 IN 1 WK) INTRAVENOUS. During the same period patient was treated with FLUOROURACIL, LEUCOVORIN CALCIUM. Patient was hospitalized. Patient died on 01/09/2005.

Irinotecan Side Effects Report #4753570-8
Irinotecan side effect was reported by a Physician from GERMANY on Aug 12, 2005. Male patient, 67 years of age, weighting 69.00 lb, was diagnosed with gastric cancer and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: acute prerenal failure, dehydration, diarrhoea, multi-organ failure, sepsis . Irinotecan dosage: 80 MG/M2 (1 IN 1 WK), INTRAVENOUS. During the same period patient was treated with FLUOROURACIL, LEUCOVORIN CALCIUM, SPIRONOLACTONE, METOCLOPRAMIDE, DURAGESIC. Patient was hospitalized. Patient died on 01/09/2005.

Irinotecan Side Effects Report #5726877-5
Irinotecan side effect was reported by a Consumer or non-health professional from INDIA on Apr 29, 2008. Male patient, weighting 105.8 lb, was diagnosed with colorectal cancer metastatic and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: anaemia, anuria, ascites, asthenia, constipation , nausea , neutropenia, sepsis . Irinotecan dosage: unknown. During the same period patient was treated with LEUCOVORIN CALCIUM, FLUOROURACIL, DOMPERIDONE, CYPROHEPTADINE, FUROSEMIDE, ONDANSETRON. Patient was hospitalized. Patient died on 04/29/2008.


Irinotecan Side Effects Report #5733837-7
Irinotecan side effect was reported by a Consumer or non-health professional from INDIA on Apr 29, 2008. Male patient, weighting 105.8 lb, was diagnosed with colorectal cancer metastatic and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: anaemia, anuria, ascites, asthenia, constipation , nausea , neutropenia, sepsis , thrombocytopenia. Irinotecan dosage: unknown. During the same period patient was treated with LEUCOVORIN CALCIUM, FLUOROURACIL, DOMPERIDONE, CYPROHEPTADINE, FUROSEMIDE, ONDANSETRON. Patient was hospitalized. Patient died on 04/29/2008.

Irinotecan Side Effects Report #5745717-1
Irinotecan side effect was reported by a Consumer or non-health professional from INDIA on May 12, 2008. Male patient, weighting 105.8 lb, was diagnosed with colorectal cancer metastatic and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: anaemia, anuria, ascites, asthenia, constipation , nausea , neutropenia, sepsis , thrombocytopenia. Irinotecan dosage: unknown. During the same period patient was treated with LEUCOVORIN CALCIUM, FLUOROURACIL, DOMPERIDONE, CYPROHEPTADINE, GALENIC, ONDANSETRON. Patient was hospitalized. Patient died on 04/29/2008.

Irinotecan Side Effects Report #6000199-X
Irinotecan side effect was reported by a Physician from BRAZIL on Dec 05, 2008. Female patient was diagnosed with colorectal cancer metastatic and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: diarrhoea, sepsis . Irinotecan dosage: unknown. During the same period patient was treated with FLUOROURACIL, FOLINIC ACID, CAPTOPRIL. Patient was hospitalized. Patient died on 11/27/2008.

Irinotecan Side Effects Report #5154629-6
Irinotecan side effect was reported by a Health Professional from NETHERLANDS on Dec 16, 2003. Male patient, 58 years of age, was diagnosed with colorectal cancer  and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: sepsis , skin infection. Irinotecan dosage: 480 MG ONCE, INTRAVENOUS. During the same period patient was treated with CAPECITABINE. Patient was hospitalized. Patient died on 11/22/2003.

Irinotecan Side Effects Report #5514694-0
Irinotecan side effect was reported by a Health Professional from JAPAN on Nov 01, 2007. Male patient, 79 years of age, was treated with Irinotecan. After drug was administered, patient experienced the following side effects: anaphylactic shock, gastrointestinal haemorrhage, myocardial infarction, sepsis . Irinotecan dosage: unknown. During the same period patient was treated with CARBOPLATIN. Patient died.


Irinotecan Side Effects Report #4669087-5
Irinotecan side effect was reported by a Physician from on May 09, 2005. Male patient, 62 years of age, weighting 96.56 lb, was treated with Irinotecan. After drug was administered, patient experienced the following side effects: asthenia, diarrhoea, fluid retention, ileus, intestinal dilatation, leukopenia, sepsis , septic shock. Irinotecan dosage: 85 MG (INTERMITTENT); 68MG. During the same period patient was treated with CISPLATIN, EXCEGRAN. Patient was hospitalized. Patient died on 02/02/2005.

Irinotecan Side Effects Report #4877433-2
Irinotecan side effect was reported by a Physician from FRANCE on Dec 28, 2005. Male patient, 56 years of age, weighting 165.3 lb, was treated with Irinotecan. After drug was administered, patient experienced the following side effects: acute respiratory failure, bone marrow failure, dyspnoea, oxygen saturation decreased, sepsis . Irinotecan dosage: 123 MG (123 MG, 1 IN 1 D), INTRAVENOUS. During the same period patient was treated with CISPLATIN, PRIMPERAN, LEXOMIL, DURAGESIC, FUROSEMIDE, VOGALENE, ATROPINE. Patient was hospitalized. Patient died on 12/20/2005.

Irinotecan Side Effects Report #4954749-2
Irinotecan side effect was reported by a Physician from FRANCE on Jan 09, 2006. Male patient, 56 years of age, weighting 165.3 lb, was treated with Irinotecan. After drug was administered, patient experienced the following side effects: acute respiratory failure, bone marrow failure, neutropenia, oxygen saturation decreased, sepsis , thrombocytopenia. Irinotecan dosage: 123 MG (123 MG, 1 IN 1 D), INTRAVENOUS. During the same period patient was treated with CISPLATIN, PRIMPERAN, LEXOMIL, DURAGESIC, LASIX, VOGALENE, ATROPINE. Patient was hospitalized. Patient died on 12/20/2005.

Irinotecan Side Effects Report #5346403-2
Irinotecan side effect was reported by a Consumer or non-health professional from SWITZERLAND on May 30, 2007. Male patient, weighting 172.0 lb, was treated with Irinotecan. After drug was administered, patient experienced the following side effects: disseminated intravascular coagulation, sepsis . Irinotecan dosage: unknown. During the same period patient was treated with CISPLATIN, FOSICOMP, FORTECORTIN. Patient was hospitalized. Patient recovered.

Irinotecan Side Effects Report #5353002-5
Irinotecan side effect was reported by a Consumer or non-health professional from SWITZERLAND on May 30, 2007. Male patient, weighting 172.0 lb, was treated with Irinotecan. After drug was administered, patient experienced the following side effects: disseminated intravascular coagulation, sepsis . Irinotecan dosage: unknown. During the same period patient was treated with CISPLATIN, FOSICOMP, FORTECORTIN. Patient was hospitalized. Patient recovered.


Irinotecan Side Effects Report #5356118-2
Irinotecan side effect was reported by a Consumer or non-health professional from SWITZERLAND on June 05, 2007. Male patient, weighting 172.0 lb, was treated with Irinotecan. After drug was administered, patient experienced the following side effects: disseminated intravascular coagulation, sepsis . Irinotecan dosage: unknown. During the same period patient was treated with CISPLATIN, FOSICOMP, FORTECORTIN, NEXIUM, HALDOL. Patient was hospitalized. Patient recovered.

Irinotecan Side Effects Report #5478930-1
Irinotecan side effect was reported by a Consumer or non-health professional from SWITZERLAND on Oct 03, 2007. Male patient, weighting 172.0 lb, was treated with Irinotecan. After drug was administered, patient experienced the following side effects: disseminated intravascular coagulation, sepsis . Irinotecan dosage: unknown. During the same period patient was treated with CISPLATIN, FOSICOMP, FORTECORTIN, NEXIUM, HALDOL. Patient was hospitalized. Patient recovered.

Irinotecan Side Effects Report #5798983-0
Irinotecan side effect was reported by a Consumer or non-health professional from SWAZILAND on June 25, 2008. Male patient, weighting 172.0 lb, was treated with Irinotecan. After drug was administered, patient experienced the following side effects: disseminated intravascular coagulation, sepsis . Irinotecan dosage: unknown. During the same period patient was treated with CISPLATIN, FOSICOMP, FORTECORTIN, NEXIUM, HALDOL. Patient was hospitalized. Patient recovered.