Ixabepilone and febrile neutropenia Patient Reports February 10, 2010

Ixabepilone Side Effects Report #5474675-2
Ixabepilone side effect was reported by a Health Professional from UNITED STATES on Sept 27, 2007. Male patient, 65 years of age, was diagnosed with pancreatic carcinoma metastatic and was treated with Ixabepilone. After drug was administered, patient experienced the following side effects: febrile neutropenia, international normalised ratio increased. Ixabepilone dosage: unknown. During the same period patient was treated with CETUXIMAB, REGLAN, MEGACE, SENOKOT. Patient was hospitalized. Patient recovered.

Ixabepilone Side Effects Report #5479607-9
Ixabepilone side effect was reported by a Health Professional from UNITED STATES on Oct 03, 2007. Male patient, 65 years of age, was diagnosed with pancreatic carcinoma metastatic and was treated with Ixabepilone. After drug was administered, patient experienced the following side effects: febrile neutropenia, hypotension, hypoxia, international normalised ratio increased, respiratory failure. Ixabepilone dosage: unknown. During the same period patient was treated with CETUXIMAB, REGLAN, MEGACE, SENOKOT. Patient was hospitalized. Patient died on 09/30/2007.

Ixabepilone Side Effects Report #5484070-8
Ixabepilone side effect was reported by a Health Professional from UNITED STATES on Oct 11, 2007. Male patient, 65 years of age, was diagnosed with pancreatic carcinoma metastatic and was treated with Ixabepilone. After drug was administered, patient experienced the following side effects: febrile neutropenia, hypotension, hypoxia, international normalised ratio increased, respiratory failure. Ixabepilone dosage: unknown. During the same period patient was treated with CETUXIMAB, REGLAN, MEGACE, SENOKOT, MORPHINE, PROCHLORPERAZINE, CEFTAZIDIME. Patient was hospitalized. Patient died on 09/30/2007.

Ixabepilone Side Effects Report #5531234-0
Ixabepilone side effect was reported by a Health Professional from UNITED STATES on Nov 29, 2007. Male patient, 65 years of age, was diagnosed with pancreatic carcinoma metastatic and was treated with Ixabepilone. After drug was administered, patient experienced the following side effects: febrile neutropenia, hypotension, hypoxia, international normalised ratio increased, malignant neoplasm progression, respiratory failure. Ixabepilone dosage: unknown. During the same period patient was treated with CETUXIMAB, REGLAN, MEGACE, SENOKOT, MORPHINE, PROCHLORPERAZINE, CEFTAZIDIME. Patient was hospitalized. Patient died on 09/30/2007.


Ixabepilone Side Effects Report #5986842-X
Ixabepilone side effect was reported by a Health Professional from UNITED STATES on Dec 05, 2008. Male patient, 65 years of age, was diagnosed with non-small cell lung cancer and was treated with Ixabepilone. After drug was administered, patient experienced the following side effects: diarrhoea, febrile neutropenia. Ixabepilone dosage: unknown. During the same period patient was treated with ADVAIR DISKUS, XANAX, ALTACE, APIDRA, AVODART, COUMADIN, DIGOXIN, DILTIAZEM CD. Patient was hospitalized. Patient died on 11/27/2008.

Ixabepilone Side Effects Report #5987536-7
Ixabepilone side effect was reported by a Health Professional from UNITED STATES on Dec 05, 2008. Male patient, 65 years of age, was diagnosed with non-small cell lung cancer and was treated with Ixabepilone. After drug was administered, patient experienced the following side effects: diarrhoea, febrile neutropenia. Ixabepilone dosage: unknown. During the same period patient was treated with ADVAIR DISKUS, XANAX, ALTACE, APIDRA, AVODART, COUMADIN, DIGOXIN, DILTIAZEM CD. Patient was hospitalized. Patient died on 11/27/2008.

Ixabepilone Side Effects Report #6006673-4
Ixabepilone side effect was reported by a Health Professional from UNITED STATES on Dec 05, 2008. Male patient, 65 years of age, was diagnosed with non-small cell lung cancer and was treated with Ixabepilone. After drug was administered, patient experienced the following side effects: diarrhoea, febrile neutropenia. Ixabepilone dosage: unknown. During the same period patient was treated with ADVAIR DISKUS, XANAX, ALTACE, APIDRA, AVODART, COUMADIN, DIGOXIN, DILTIAZEM CD. Patient was hospitalized. Patient died on 11/27/2008.

Ixabepilone Side Effects Report #4667596-6
Ixabepilone side effect was reported by a Health Professional from on Mar 21, 2005. Male patient, 77 years of age, was diagnosed with neoplasm malignant and was treated with Ixabepilone. After drug was administered, patient experienced the following side effects: acidosis, atrial fibrillation , cardio-respiratory arrest, electrolyte imbalance, fatigue, febrile neutropenia, herpes simplex , hypocalcaemia, hypomagnesaemia. Ixabepilone dosage: unknown. During the same period patient was treated with KETOCONAZOLE, BENADRYL, ZANTAC. Patient was hospitalized. Patient died on 04/06/2005.

Ixabepilone Side Effects Report #4675651-X
Ixabepilone side effect was reported by a Health Professional from on Mar 21, 2005. Male patient, 77 years of age, was diagnosed with neoplasm malignant and was treated with Ixabepilone. After drug was administered, patient experienced the following side effects: arrhythmia , cardio-respiratory arrest, coma hepatic, electrolyte imbalance, fatigue, febrile neutropenia, haemodialysis, hepatic failure, hyperkalaemia. Ixabepilone dosage: unknown. During the same period patient was treated with KETOCONAZOLE, BENADRYL, ZANTAC. Patient was hospitalized. Patient died on 04/06/2005.


Ixabepilone Side Effects Report #4562053-X
Ixabepilone side effect was reported by a Health Professional from on Jan 10, 2005. Female patient, 43 years of age, was diagnosed with neoplasm malignant and was treated with Ixabepilone. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, fatigue, febrile neutropenia, oral candidiasis, pain , rash . Ixabepilone dosage: 600 MG, INTRAVENOUS. During the same period patient was treated with KETOCONAZOLE. Patient was hospitalized. Patient recovered.

Ixabepilone Side Effects Report #4588630-8
Ixabepilone side effect was reported by a Consumer or non-health professional from on Feb 02, 2005. Female patient, 43 years of age, was diagnosed with neoplasm malignant and was treated with Ixabepilone. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, fatigue, febrile neutropenia, neutrophil count decreased, oral candidiasis, pain , rash , stomatitis. Ixabepilone dosage: 60 MG, INTRAVENOUS. During the same period patient was treated with KETOCONAZOLE. Patient was hospitalized. Patient recovered.

Ixabepilone Side Effects Report #4599367-3
Ixabepilone side effect was reported by a Consumer or non-health professional from on Jan 10, 2005. Female patient, 43 years of age, was diagnosed with neoplasm malignant and was treated with Ixabepilone. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood culture positive, fatigue, febrile neutropenia, oral candidiasis, pain , rash . Ixabepilone dosage: 60 MG; IV. During the same period patient was treated with KETOCONAZOLE. Patient was hospitalized. Patient recovered.

Ixabepilone Side Effects Report #5828671-3
Ixabepilone side effect was reported by a Health Professional from UNITED STATES on July 24, 2008. Female patient, 70 years of age, weighting 143.3 lb, was diagnosed with breast cancer metastatic, diabetes mellitus, nutritional support , neuropathy peripheral, cardiac failure congestive, hyperlipidaemia, bronchitis  and was treated with Ixabepilone. After drug was administered, patient experienced the following side effects: cardiac failure congestive, febrile neutropenia, sepsis . Ixabepilone dosage: unknown. During the same period patient was treated with GLYBURIDE, NEURONTIN, DIGOXIN, LASIX, SIMVASTATIN, DIOVAN, ADVAIR DISKUS. Patient was hospitalized. Patient recovered.

Ixabepilone Side Effects Report #5849932-8
Ixabepilone side effect was reported by a Health Professional from UNITED STATES on Aug 14, 2008. Female patient, 70 years of age, weighting 143.3 lb, was diagnosed with breast cancer metastatic, diabetes mellitus, nutritional support , neuropathy peripheral, cardiac failure congestive, hyperlipidaemia, bronchitis  and was treated with Ixabepilone. After drug was administered, patient experienced the following side effects: cardiac failure congestive, febrile neutropenia, sepsis . Ixabepilone dosage: unknown. During the same period patient was treated with GLYBURIDE, NEURONTIN, DIGOXIN, LASIX, SIMVASTATIN, DIOVAN, ADVAIR DISKUS. Patient was hospitalized. Patient recovered.


Ixabepilone Side Effects Report #5887829-8
Ixabepilone side effect was reported by a Health Professional from UNITED STATES on Sept 16, 2008. Female patient, 70 years of age, weighting 143.3 lb, was diagnosed with breast cancer metastatic, diabetes mellitus, nutritional support , neuropathy peripheral, cardiac failure congestive, hyperlipidaemia, bronchitis  and was treated with Ixabepilone. After drug was administered, patient experienced the following side effects: cardiac failure congestive, febrile neutropenia, sepsis . Ixabepilone dosage: 40 MG/M2 EVERY 21 DAYS. During the same period patient was treated with GLYBURIDE, NEURONTIN, DIGOXIN, LASIX, SIMVASTATIN, DIOVAN, ADVAIR DISKUS. Patient was hospitalized. Patient recovered.

Ixabepilone Side Effects Report #5940682-6
Ixabepilone side effect was reported by a Health Professional from UNITED STATES on Nov 03, 2008. Female patient, 70 years of age, weighting 143.3 lb, was diagnosed with breast cancer metastatic, diabetes mellitus, nutritional support , neuropathy peripheral, cardiac failure congestive, hyperlipidaemia, bronchitis  and was treated with Ixabepilone. After drug was administered, patient experienced the following side effects: cardiac failure congestive, febrile neutropenia, sepsis . Ixabepilone dosage: 40 MG/M2 EVERY 21 DAYS. During the same period patient was treated with GLYBURIDE, NEURONTIN, DIGOXIN, LASIX, SIMVASTATIN, DIOVAN, ADVAIR DISKUS. Patient was hospitalized. Patient recovered.

Ixabepilone Side Effects Report #5941747-5
Ixabepilone side effect was reported by a Health Professional from UNITED STATES on Oct 31, 2008. Female patient, 46 years of age, weighting 174.2 lb, was diagnosed with breast cancer metastatic, dyspepsia, pain , hypertension, nausea , prophylaxis and was treated with Ixabepilone. After drug was administered, patient experienced the following side effects: blood glucose increased, dehydration, diarrhoea, febrile neutropenia, renal failure acute, vomiting. Ixabepilone dosage: unknown. During the same period patient was treated with ZANTAC, TYLENOL, TRAMADOL, DOXAZOSIN MESYLATE, LORAZEPAM, PROCHLORPERAZINE, DEXAMETHASONE. Patient was hospitalized. Patient recovered.

Ixabepilone Side Effects Report #5990107-X
Ixabepilone side effect was reported by a Health Professional from UNITED STATES on Dec 09, 2008. Female patient, 46 years of age, weighting 174.2 lb, was diagnosed with breast cancer metastatic, dyspepsia, pain , hypertension, nausea , prophylaxis and was treated with Ixabepilone. After drug was administered, patient experienced the following side effects: blood glucose increased, dehydration, diarrhoea, febrile neutropenia, vomiting. Ixabepilone dosage: unknown. During the same period patient was treated with ZANTAC, TYLENOL, TRAMADOL, DOXAZOSIN MESYLATE, LORAZEPAM, PROCHLORPERAZINE, DEXAMETHASONE. Patient was hospitalized. Patient recovered.

Ixabepilone Side Effects Report #5719622-0
Ixabepilone side effect was reported by a Consumer or non-health professional from FRANCE on Apr 22, 2008. Female patient, 33 years of age, weighting 200.6 lb, was diagnosed with breast cancer  and was treated with Ixabepilone. After drug was administered, patient experienced the following side effects: asthenia, brain scan abnormal, constipation , diarrhoea, dizziness , febrile neutropenia, oral fungal infection. Ixabepilone dosage: CUMULATIVE DOSE SINCE FIRST ADMINISTRATION: 100 MG. During the same period patient was treated with ENDOXAN, EPIRUBICIN, FLUOROURACIL, NEULASTA, GRANOCYTE. Patient was hospitalized. Patient recovered.


Ixabepilone Side Effects Report #5753351-2
Ixabepilone side effect was reported by a Consumer or non-health professional from SPAIN on May 28, 2008. Female patient, 50 years of age, was treated with Ixabepilone. After drug was administered, patient experienced the following side effects: bacteraemia, febrile neutropenia, mucosal inflammation, pelvic fracture. Ixabepilone dosage: unknown. During the same period patient was treated with PREDNISONE, OXYCODONE, IBUROFEN, PREGABALIN, THIETHYLPERAZINE, OMEPRAZOLE. Patient was hospitalized and became disabled. Patient recovered.