Letrozole and aspartate aminotransferase increased Patient Reports February 10, 2010

Letrozole Side Effects Report #4907878-3
Letrozole side effect was reported by a Consumer or non-health professional from SINGAPORE on Jan 19, 2005. Female patient, 56 years of age, was diagnosed with breast cancer stage iv and was treated with Letrozole. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blister, blood albumin decreased, blood bilirubin increased, conjunctivitis, dermatitis bullous, genital erosion, haemoglobin decreased. Letrozole dosage: 2.5 MG, QD. During the same period patient was treated with OMEPRAZOLE, DEXAMETHASONE. Patient was hospitalized. Patient died on 01/06/2005.

Letrozole Side Effects Report #5283076-1
Letrozole side effect was reported by a Physician from UNITED KINGDOM on Mar 19, 2007. Female patient, 72 years of age, was diagnosed with breast cancer metastatic and was treated with Letrozole. After drug was administered, patient experienced the following side effects: abdominal pain , aspartate aminotransferase increased, blood amylase increased, pancreatitis. Letrozole dosage: 2.5 MG, QD. Patient was hospitalized. Patient recovered.

Letrozole Side Effects Report #5334266-0
Letrozole side effect was reported by a Physician from UNITED KINGDOM on May 21, 2007. Female patient, 72 years of age, was diagnosed with breast cancer metastatic and was treated with Letrozole. After drug was administered, patient experienced the following side effects: abdominal pain , aspartate aminotransferase increased, blood amylase increased, chest pain , clostridial infection, dehydration, lip ulceration, pancreatitis, pyrexia. Letrozole dosage: unknown. During the same period patient was treated with EXEMESTANE, ACYCLOVIR, CYCLIZINE, DOMPERIDONE, VITAMIN CAP, BONJELA, PARACETAMOL. Patient was hospitalized. Patient recovered.

Letrozole Side Effects Report #5146556-5
Letrozole side effect was reported by a Physician from on Nov 02, 2006. Female patient, 59 years of age, was diagnosed with breast cancer metastatic and was treated with Letrozole. After drug was administered, patient experienced the following side effects: abdominal pain upper, alanine aminotransferase increased, aspartate aminotransferase increased, blood alkaline phosphatase increased, hepatic function abnormal, metastases to liver, nausea , oedema peripheral. Letrozole dosage: 2.5MG. Patient was hospitalized. Patient recovered.


Letrozole Side Effects Report #5153831-7
Letrozole side effect was reported by a Physician from on Nov 02, 2006. Female patient, 59 years of age, was diagnosed with breast cancer metastatic and was treated with Letrozole. After drug was administered, patient experienced the following side effects: abdominal pain upper, alanine aminotransferase increased, aspartate aminotransferase increased, blood alkaline phosphatase increased, hepatic encephalopathy, hepatic function abnormal, metastases to liver, nausea . Letrozole dosage: 2.5MG. Patient was hospitalized. Patient died on 11/03/2006.

Letrozole Side Effects Report #5157135-8
Letrozole side effect was reported by a Physician from UNITED KINGDOM on Dec 12, 2005. Female patient, 58 years of age, was diagnosed with breast cancer metastatic and was treated with Letrozole. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, dyspnoea, granuloma, hepatic function abnormal, malignant neoplasm progression, thrombocytopenia. Letrozole dosage: 2.5 MG, QD. Patient was hospitalized. Patient died on 06/09/2006.

Letrozole Side Effects Report #5212861-7
Letrozole side effect was reported by a Physician from UNITED KINGDOM on Jan 10, 2007. Female patient, 57 years of age, was diagnosed with breast cancer metastatic and was treated with Letrozole. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood bilirubin increased, gamma-glutamyltransferase increased. Letrozole dosage: 2.5 MG, QD. Patient recovered.

Letrozole Side Effects Report #5235526-4
Letrozole side effect was reported by a Physician from UNITED KINGDOM on Jan 30, 2007. Female patient, 57 years of age, was diagnosed with breast cancer metastatic and was treated with Letrozole. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood bilirubin increased, cystitis, gamma-glutamyltransferase increased. Letrozole dosage: 2.5 MG, QD. Patient recovered.

Letrozole Side Effects Report #5247561-0
Letrozole side effect was reported by a Physician from UNITED KINGDOM on Feb 14, 2007. Female patient, 57 years of age, was diagnosed with breast cancer metastatic and was treated with Letrozole. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood bilirubin increased, cystitis, gamma-glutamyltransferase increased, nausea . Letrozole dosage: 2.5 MG, QD. Patient recovered.


Letrozole Side Effects Report #5266169-4
Letrozole side effect was reported by a Physician from UNITED KINGDOM on Mar 02, 2007. Female patient, 57 years of age, was diagnosed with breast cancer metastatic and was treated with Letrozole. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood bilirubin increased, cystitis, gamma-glutamyltransferase increased, nausea . Letrozole dosage: 2.5 MG, QD. Patient recovered.

Letrozole Side Effects Report #5275616-3
Letrozole side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on Mar 14, 2007. Female patient, 57 years of age, was diagnosed with breast cancer metastatic and was treated with Letrozole. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood bilirubin increased, cystitis, gamma-glutamyltransferase increased, hepatic steatosis, nausea . Letrozole dosage: 2.5 MG, QD. Patient recovered.

Letrozole Side Effects Report #5880274-0
Letrozole side effect was reported by a Health Professional from UNITED STATES on Sept 05, 2008. Female patient, 75 years of age, was diagnosed with breast cancer , disease recurrence, renal cancer and was treated with Letrozole. After drug was administered, patient experienced the following side effects: abdominal pain lower, acute hepatic failure, alanine aminotransferase increased, arthralgia, aspartate aminotransferase increased, bilirubin conjugated increased, blood bilirubin increased, blood creatine phosphokinase increased, blood creatinine increased. Letrozole dosage: unknown. During the same period patient was treated with SUNITINIB MALATE, ALENDRONATE, IRBESARTAN, DOCUSATE, PROCHLORPERAZINE, CLONIDINE, LANSOPRAZOLE. Patient was hospitalized. Patient recovered.