Mabthera and acute respiratory distress syndrome 
Mabthera and acute respiratory distress syndrome Patient Reports February 09, 2010
Mabthera Side Effects Report #5504118-1
Mabthera side effect was reported by a Physician from SWITZERLAND on Oct 22, 2007. Male patient was diagnosed with transplant rejection and was treated with Mabthera. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome. Mabthera dosage: unknown. Patient recovered.
Mabthera Side Effects Report #5523281-X
Mabthera side effect was reported by a Physician from SWITZERLAND on Nov 09, 2007. Male patient, weighting 149.9 lb, was diagnosed with transplant rejection and was treated with Mabthera. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome. Mabthera dosage: 375 MG/M2, UNK. Patient was hospitalized. Patient recovered.
Mabthera Side Effects Report #5534730-5
Mabthera side effect was reported by a Consumer or non-health professional from SWITZERLAND on Nov 24, 2007. Male patient, weighting 149.9 lb, was diagnosed with transplant rejection and was treated with Mabthera. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome. Mabthera dosage: 375 MG/M2, UNK. Patient was hospitalized. Patient recovered.
Mabthera Side Effects Report #5167488-2
Mabthera side effect was reported by a Physician from UNITED KINGDOM on Nov 21, 2006. Female patient, 45 years of age, was diagnosed with systemic lupus erythematosus and was treated with Mabthera. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, brain stem syndrome, cerebellar syndrome, coordination abnormal, cyanosis, disease recurrence, dysarthria, herpes zoster, intestinal obstruction. Mabthera dosage: 375 MG/M2, 1/WEEK, INTRAVENOUS. During the same period patient was treated with AMLODIPINE BESYLATE, CALCICHEW D, HYDROXYCHLLOROQUINE, LEVOTHYROXINE, CLARITIN, NUVELLE. Patient died on 07/10/2006.
Mabthera Side Effects Report #5176909-0
Mabthera side effect was reported by a Physician from UNITED KINGDOM on Nov 29, 2006. Female patient, 45 years of age, was diagnosed with systemic lupus erythematosus and was treated with Mabthera. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, arthralgia, brain stem syndrome, cerebellar syndrome, coordination abnormal, dysarthria, dysphagia, hiv infection
, intestinal obstruction. Mabthera dosage: 375 MG/M2, 1/WEEK, INTRAVENOUS; 375 MG/M2, SINGLE. During the same period patient was treated with AMLODIPINE BESYLATE, CALCICHEW D, HYDROXYCHLOROQUINE, LEVOTHYROXINE, CLARITIN, NUVELLE, FOLIC ACID. Patient died on 07/10/2006.Mabthera Side Effects Report #5928538-6
Mabthera side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on Oct 08, 2008. Female patient, 20 years of age, was diagnosed with systemic lupus erythematosus and was treated with Mabthera. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, diffuse alveolar damage, pneumonia
, renal failure chronic. Mabthera dosage: 2000 MG, Q2W. During the same period patient was treated with ANTIHYPERTENSIVES. Patient died.Mabthera Side Effects Report #5589560-5
Mabthera side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on Jan 07, 2008. Female patient was diagnosed with systemic lupus erythematosus, raynaud's phenomenon, osteoporosis
, hypothyroidism, hypersensitivity, premature menopause and was treated with Mabthera. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, b-lymphocyte count decreased, disease recurrence, herpes zoster, intestinal obstruction, pneumonia aspiration, post procedural pneumonia, progressive multifocal leukoencephalopathy, respiratory failure. Mabthera dosage: 375 MG/M2, 1/WEEK. During the same period patient was treated with AMLODIPINE, CALCICHEW D, HYDROXYCHLOROQUINE, LEVOTHYROXINE, CLARITIN, NUVELLE. Patient died on 07/10/2006.Mabthera Side Effects Report #5835679-0
Mabthera side effect was reported by a Physician from TAIWAN, PROVINCE OF CHINA on July 22, 2008. Female patient, 59 years of age, was diagnosed with rheumatoid arthritis
and was treated with Mabthera. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome. Mabthera dosage: unknown. During the same period patient was treated with METHYLPREDNISOLONE, HYDROXYCHLOROQUINE SULPHATE, METHOTREXATE. Patient was hospitalized. Patient recovered.Mabthera Side Effects Report #4718903-7
Mabthera side effect was reported by a Physician from GERMANY on July 11, 2005. Male patient, 70 years of age, was diagnosed with non-hodgkin's lymphoma and was treated with Mabthera. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, cardiopulmonary failure, diabetes mellitus, gastrointestinal haemorrhage, hyperglycaemia, hypovolaemia, pancytopenia. Mabthera dosage: unknown. During the same period patient was treated with CYCLOPHOSPHAMIDE, DOXORUBICIN, VINCRISTINE, PREDNISONE. Patient was hospitalized. Patient recovered.
Mabthera Side Effects Report #4719212-2
Mabthera side effect was reported by a Physician from GERMANY on July 11, 2005. Male patient, 70 years of age, was diagnosed with non-hodgkin's lymphoma and was treated with Mabthera. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, aortic valve incompetence, aortic valve sclerosis, atelectasis, atrial hypertrophy, cardiopulmonary failure, depressed level of consciousness, diabetes mellitus, dilatation atrial. Mabthera dosage: unknown. During the same period patient was treated with CYCLOPHOSPHAMIDE, DOXORUBICIN HYDROCHLORIDE, VINCRISTINE, PREDNISONE. Patient was hospitalized. Patient recovered.
Mabthera Side Effects Report #5310508-2
Mabthera side effect was reported by a Physician from GERMANY on Apr 18, 2007. Female patient, weighting 134.5 lb, was diagnosed with non-hodgkin's lymphoma and was treated with Mabthera. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, bronchopulmonary aspergillosis, multi-organ failure, sepsis
. Mabthera dosage: unknown. During the same period patient was treated with CYCLOPHOSPHAMIDE, DOXORUBICIN, VINCRISTINE, PREDNISONE. Patient died on 04/09/2007.Mabthera Side Effects Report #5587535-3
Mabthera side effect was reported by a Physician from UNITED KINGDOM on Jan 02, 2008. Female patient was diagnosed with non-hodgkin's lymphoma and was treated with Mabthera. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, cytomegalovirus infection
, pneumocystis jiroveci pneumonia, respiratory failure. Mabthera dosage: 375 MG/M2, UNK. During the same period patient was treated with OCTAGAM. Patient died on 10/06/2007.Mabthera Side Effects Report #4737407-9
Mabthera side effect was reported by a Physician from BELGIUM on July 18, 2005. Male patient, 62 years of age, weighting 154.3 lb, was diagnosed with mantle cell lymphoma and was treated with Mabthera. After drug was administered, patient experienced the following side effects: abdominal pain
, acute respiratory distress syndrome, blood creatine increased, blood glucose increased, blood urea increased, haematocrit decreased, haemoglobin decreased, hepatitis , herpes zoster. Mabthera dosage: unknown. Patient died on 06/21/2005.Mabthera Side Effects Report #4759255-6
Mabthera side effect was reported by a Physician from BELGIUM on Aug 26, 2005. Male patient, 62 years of age, weighting 154.3 lb, was diagnosed with mantle cell lymphoma and was treated with Mabthera. After drug was administered, patient experienced the following side effects: abdominal pain
, activated partial thromboplastin time prolonged, acute respiratory distress syndrome, b-lymphocyte count decreased, blood albumin decreased, blood amylase increased, blood creatinine increased, blood glucose increased, blood urea increased. Mabthera dosage: unknown. Patient died on 06/21/2005.Mabthera Side Effects Report #5761697-7
Mabthera side effect was reported by a Health Professional from UNITED KINGDOM on May 26, 2008. Male patient, 46 years of age, was diagnosed with idiopathic thrombocytopenic purpura and was treated with Mabthera. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, bronchopulmonary aspergillosis, neutropenia, pneumocystis jiroveci pneumonia. Mabthera dosage: unknown. Patient was hospitalized. Patient died.
Mabthera Side Effects Report #4961436-3
Mabthera side effect was reported by a Physician from FRANCE on Mar 20, 2006. Female patient, 40 years of age, weighting 209.4 lb, was diagnosed with diffuse large b-cell lymphoma and was treated with Mabthera. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, anaemia, bone marrow failure, cardiac arrest
, cardiac failure, coagulopathy, deep vein thrombosis , dialysis , gastroenteritis . Mabthera dosage: unknown. During the same period patient was treated with DOXORUBICIN HYDROCHLORIDE, ENDOXAN, VINDESINE, BLEOMYCIN SULPHATE, METHOTREXATE, BACTRIM DS. Patient recovered.Mabthera Side Effects Report #4961632-5
Mabthera side effect was reported by a Consumer or non-health professional from FRANCE on Mar 20, 2006. Female patient, 40 years of age, weighting 209.4 lb, was diagnosed with diffuse large b-cell lymphoma and was treated with Mabthera. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, bone marrow failure, cardiac arrest
, cardiac failure, coagulopathy, deep vein thrombosis , dialysis , gastroenteritis , hypovolaemic shock. Mabthera dosage: unknown. During the same period patient was treated with BLEOMYCIN SULPHATE, VINDESINE, DOXORUBICINE, ENDOXAN, METHOTREXATE, BACTRIM DS, CEFIXIME. Patient recovered.Mabthera Side Effects Report #4978806-X
Mabthera side effect was reported by a Physician from FRANCE on Apr 05, 2006. Female patient, 40 years of age, weighting 209.4 lb, was diagnosed with diffuse large b-cell lymphoma and was treated with Mabthera. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, anaemia, axillary vein thrombosis, bacillus infection, bone marrow failure, cardiac arrest
, cardiac failure, coagulopathy, deep vein thrombosis . Mabthera dosage: unknown. During the same period patient was treated with BLEOMYCIN SULPHATE, VINDESINE, DOXORUBICIN HYDROCHLORIDE, ENDOXAN, METHOTREXATE, BACTRIM DS, CEFIXIME. Patient recovered.Mabthera Side Effects Report #4978864-2
Mabthera side effect was reported by a Physician from FRANCE on Apr 05, 2006. Female patient, 40 years of age, weighting 209.4 lb, was diagnosed with diffuse large b-cell lymphoma and was treated with Mabthera. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, anaemia, axillary vein thrombosis, blood pressure abnormal, bone marrow failure, cardiac arrest
, cardiac failure, coagulopathy, deep vein thrombosis . Mabthera dosage: unknown. During the same period patient was treated with DOXORUBICIN, ENDOXAN, VINDESINE, BLEOMYCIN, METHOTREXATE, BACTRIMTE. Patient died on 03/08/2006.Mabthera Side Effects Report #4998613-1
Mabthera side effect was reported by a Physician from FRANCE on Apr 26, 2006. Female patient, 40 years of age, weighting 209.4 lb, was diagnosed with diffuse large b-cell lymphoma and was treated with Mabthera. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, bone marrow failure, cardiac arrest
, cardiac failure, coagulopathy, deep vein thrombosis , dialysis , dyspnoea. Mabthera dosage: unknown. During the same period patient was treated with BLEOMYCINE, VINDESINE, DOXORUBICIN HYDROCHLORIDE, CYCLOPHOSPHAMIDE, METHOTREXATE, BACTRIM DS, CEFIXIME. Patient died.Mabthera Side Effects Report #5006746-9
Mabthera side effect was reported by a Physician from FRANCE on May 05, 2006. Female patient, 40 years of age, weighting 209.4 lb, was diagnosed with diffuse large b-cell lymphoma and was treated with Mabthera. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, bone marrow failure, cardiac arrest
, cardiac failure, cardiovascular disorder, coagulopathy, deep vein thrombosis , dialysis , dyspnoea. Mabthera dosage: unknown. During the same period patient was treated with DOXORUBICIN HYDROCHLORIDE, CYCLOPHOSPHAMIDE, VINDESINE, BLEOMYCIN SULPHATE, METHOTREXATE, BACTRIM DS. Patient died on 03/08/2006.Mabthera Side Effects Report #5014378-1
Mabthera side effect was reported by a Physician from FRANCE on May 16, 2006. Female patient, 40 years of age, weighting 209.4 lb, was diagnosed with diffuse large b-cell lymphoma and was treated with Mabthera. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, axillary vein thrombosis, blood culture positive, bone marrow failure, cardiac arrest
, cardiac failure, coagulopathy, deep vein thrombosis , dialysis . Mabthera dosage: unknown. During the same period patient was treated with BLEOMYCIN SULPHATE, VINDESINE, DOXORUBICIN HYDROCHLORIDE, ENDOXAN, METHOTREXATE, BACTRIM DS, CEFIXIME. Patient died on 03/08/2006.Mabthera Side Effects Report #5640568-0
Mabthera side effect was reported by a Physician from UNITED STATES on Feb 19, 2008. Male patient, weighting 231.5 lb, was diagnosed with diffuse large b-cell lymphoma and was treated with Mabthera. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome. Mabthera dosage: 375 MG/M2, UNK. During the same period patient was treated with ENZASTAURIN, GEMCITABINE, OXALIPLATIN, LASILIX, SPIRIVA, DEROXAT, PLAVIX, IKOREL. Patient was hospitalized. Patient died on 01/21/2008.
Mabthera Side Effects Report #5675213-1
Mabthera side effect was reported by a Physician from UNITED STATES on Mar 13, 2008. Male patient, weighting 231.5 lb, was diagnosed with diffuse large b-cell lymphoma and was treated with Mabthera. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome. Mabthera dosage: 375 MG/M2, UNK. During the same period patient was treated with ENZASTAURIN, GEMCITABINE, OXALIPLATIN, LASILIX, SPIRIVA, DEROXAT, PLAVIX, IKOREL. Patient was hospitalized. Patient died on 01/21/2008.
Mabthera Side Effects Report #5782997-0
Mabthera side effect was reported by a Physician from UNITED STATES on June 16, 2008. Male patient, weighting 231.5 lb, was diagnosed with diffuse large b-cell lymphoma and was treated with Mabthera. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, lung infection. Mabthera dosage: 375 MG/M2, UNK. During the same period patient was treated with ENZASTAURIN, GEMCITABINE, OXALIPLATIN, LASIX, SPIRIVA, PAROXETINE, PLAVIX, IKOREL. Patient was hospitalized. Patient died on 01/21/2008.
Mabthera Side Effects Report #4759253-2
Mabthera side effect was reported by a Physician from BELGIUM on Aug 16, 2005. Male patient, 22 years of age, was diagnosed with congenital syphilitic osteochondritis and was treated with Mabthera. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, pulmonary haemorrhage. Mabthera dosage: 750 MG, INTRAVENOUS. During the same period patient was treated with CYCLOPHOSPHAMIDE, CORTICOIDS NOS, PLASMAPHERESIS, IMMUNE GLOBULIN INTRAVENOUS. Patient died on 08/16/2005.
Mabthera Side Effects Report #5677618-1
Mabthera side effect was reported by a Health Professional from SWEDEN on Mar 12, 2008. Male patient, 85 years of age, was diagnosed with chronic lymphocytic leukaemia and was treated with Mabthera. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, pulmonary fibrosis
. Mabthera dosage: unknown. During the same period patient was treated with SENDOXAN, ONCOVIN, DOXORUBICIN, PREDNISOLONE. Patient died on 08/25/2006.Mabthera Side Effects Report #5671420-2
Mabthera side effect was reported by a Health Professional from UNITED KINGDOM on Mar 06, 2008. Male patient, 84 years of age, was diagnosed with chronic lymphocytic leukaemia and was treated with Mabthera. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, pulmonary fibrosis
. Mabthera dosage: unknown. During the same period patient was treated with SENDOXAN, ONCOVIN, DOXORUBICIN, PREDNISOLONE. Patient died.Mabthera Side Effects Report #4640594-4
Mabthera side effect was reported by a Health Professional from on Apr 07, 2005. Male patient, 63 years of age, was diagnosed with chronic lymphocytic leukaemia and was treated with Mabthera. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, agranulocytosis, hypoxia, lung disorder, platelet count abnormal, pyrexia, renal failure acute, tumour lysis syndrome. Mabthera dosage: 700 MG, INTRAVENOUS. During the same period patient was treated with DOXORUBICIN HYDROCHLORIDE, CYCLOPHOSPHAMIDE, ONCOVIN, FLUDARABINE PHOSPHATE. Patient was hospitalized. Patient died on 02/13/2003.
Mabthera Side Effects Report #4989031-0
Mabthera side effect was reported by a Health Professional from BELGIUM on Apr 11, 2006. Male patient, 58 years of age, weighting 183.0 lb, was diagnosed with chronic lymphocytic leukaemia and was treated with Mabthera. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, disseminated intravascular coagulation, renal failure acute, septic shock. Mabthera dosage: 750 MG, INTRAVENOUS. During the same period patient was treated with CYCLOPHOSPHAMIDE, FLUDARABINE, AVELOX, ZOVIRAX. Patient died on 04/09/2006.
Mabthera Side Effects Report #4992483-3
Mabthera side effect was reported by a Physician from BELGIUM on Apr 19, 2006. Male patient, 58 years of age, weighting 183.0 lb, was diagnosed with chronic lymphocytic leukaemia and was treated with Mabthera. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, bronchopneumonia, disseminated intravascular coagulation, renal failure acute, septic shock. Mabthera dosage: 750 MG, UNK, INTRAVENOUS. During the same period patient was treated with CYCLOPHOSPHAMIDE, FLUDARABINE, AVELOX, ZOVIRAX. Patient died on 04/09/2006.
Mabthera Side Effects Report #4996452-9
Mabthera side effect was reported by a Physician from BELGIUM on Apr 21, 2006. Male patient, 58 years of age, weighting 183.0 lb, was diagnosed with chronic lymphocytic leukaemia and was treated with Mabthera. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, bronchopneumonia, disseminated intravascular coagulation, haematocrit decreased, haemodynamic instability, haemoglobin decreased, hypotension, hypoxia, metabolic acidosis. Mabthera dosage: 750 MG, INTRAVENOUS. During the same period patient was treated with CYCLOPHOSPHAMIDE, FLUDARABINE, AVELOX, ZOVIRAX. Patient died on 04/09/2006.
Mabthera Side Effects Report #5008475-4
Mabthera side effect was reported by a Physician from BELGIUM on May 05, 2006. Male patient, 58 years of age, weighting 183.0 lb, was diagnosed with chronic lymphocytic leukaemia and was treated with Mabthera. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, alanine aminotransferase increased, aplasia, aspartate aminotransferase increased, blood glucose increased, blood lactate dehydrogenase increased, bronchopneumonia, disseminated intravascular coagulation. Mabthera dosage: 750 MG, INTRAVENOUS. During the same period patient was treated with CYCLOPHOSPHAMIDE, FLUDARABINE, AVELOX, ZOVIRAX. Patient died on 04/09/2006.
Mabthera Side Effects Report #5012256-5
Mabthera side effect was reported by a Physician from BELGIUM on May 11, 2006. Male patient, 58 years of age, weighting 183.0 lb, was diagnosed with chronic lymphocytic leukaemia and was treated with Mabthera. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, alanine aminotransferase increased, aplasia, aspartate aminotransferase increased, blood lactate dehydrogenase increased, bronchopneumonia, disseminated intravascular coagulation, haematocrit decreased, haemodynamic instability. Mabthera dosage: 750 MG, UNK, INTRAVENOUS. During the same period patient was treated with CYCLOPHOSPHAMIDE, FLUDARABINE, AVELOX, ZOVIRAX. Patient died on 04/09/2006.
Mabthera Side Effects Report #5076269-X
Mabthera side effect was reported by a Health Professional from FRANCE on Aug 03, 2006. Male patient was diagnosed with castleman's disease and was treated with Mabthera. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, autoimmune neutropenia, castleman's disease, condition aggravated, cyclic neutropenia, histiocytosis haematophagic, humoral immune defect, hypoxia. Mabthera dosage: 375 MG/M2, 4/WEEK. During the same period patient was treated with VINBLASTINE SULPHATE, EFAVIRENZ, AMPRENAVIR, LOPINAVIR. Patient died.
Mabthera Side Effects Report #4825010-1
Mabthera side effect was reported by a Consumer or non-health professional from FRANCE on Oct 26, 2005. Male patient was diagnosed with castleman's disease and was treated with Mabthera. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, histiocytosis haematophagic, lactic acidosis, multi-organ disorder, myelocytosis, plasmacytosis, white blood cell count increased. Mabthera dosage: 375 MG/M2, 4/WEEK,UNK. During the same period patient was treated with VINBLASTINE SULPHATE, EFAVIRENZ, AMPRENAVIR, LOPINAVIR. Patient died.
Mabthera Side Effects Report #5625265-X
Mabthera side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on Feb 01, 2008. Male patient, child 3 years of age, was diagnosed with b-cell type acute leukaemia, pneumocystis jiroveci pneumonia and was treated with Mabthera. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome. Mabthera dosage: unknown. During the same period patient was treated with ANTIBIOTICS, AMPHOTERICIN B, VANCOMYCIN, SULPERAZONE, BACTRIM. Patient died on 01/15/2008.
Mabthera Side Effects Report #4952051-6
Mabthera side effect was reported by a Health Professional from THAILAND on Mar 10, 2006. Male patient, 73 years of age, weighting 130.1 lb, was diagnosed with b-cell lymphoma and was treated with Mabthera. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, anorexia, blood culture positive, blood pressure decreased, fungal infection
, nosocomial infection, pleural effusion, pneumonia bacterial, pseudomonas infection. Mabthera dosage: 100 MG, INTRAVENOUS. During the same period patient was treated with CYCLOPHOSPHAMIDE, MITOXANTRONE, FLUDARABINE. Patient was hospitalized. Patient died on 03/03/2006.Mabthera Side Effects Report #5713620-9
Mabthera side effect was reported by a Physician from UNITED KINGDOM on Apr 10, 2008. Female patient was diagnosed with anaemia haemolytic autoimmune and was treated with Mabthera. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, agranulocytosis, candidiasis, infection
, septic shock. Mabthera dosage: unknown. Patient was hospitalized. Patient recovered.Mabthera Side Effects Report #4765541-6
Mabthera side effect was reported by a Physician from BELGIUM on Aug 19, 2005. Male patient, 22 years of age, weighting 176.4 lb, was treated with Mabthera. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, pulmonary haemorrhage. Mabthera dosage: 750 MG, INTRAVENOUS. During the same period patient was treated with METHYLPREDNISOLONE, CYCLOPHOSPHAMIDE, CORTICOIDS NOR, OLASMAPHERESIS. Patient died on 08/16/2005.