Mabthera and bone marrow failure 
Mabthera and bone marrow failure Patient Reports February 09, 2010
Mabthera Side Effects Report #5647849-5
Mabthera side effect was reported by a Physician from UNITED KINGDOM on Feb 21, 2008. Female patient, child 12 years of age, was diagnosed with systemic lupus erythematosus and was treated with Mabthera. After drug was administered, patient experienced the following side effects: bone marrow failure, bradycardia, chest pain
, hypotension, pyrexia. Mabthera dosage: 1000 MG, QD. During the same period patient was treated with CYCLOPHOSPHAMIDE, AZATHIOPRINE, CORTICOSTEROIDS, CYCLOSPORINE, GANCICLOVIR. Patient was hospitalized. Patient recovered.Mabthera Side Effects Report #5660803-2
Mabthera side effect was reported by a Physician from UNITED KINGDOM on Feb 29, 2008. Male patient, child 12 years of age, was diagnosed with systemic lupus erythematosus and was treated with Mabthera. After drug was administered, patient experienced the following side effects: autoimmune thrombocytopenia, bone marrow failure, bradycardia, chest pain
, hypotension, lymphocyte percentage decreased, neutrophil percentage increased, pyrexia. Mabthera dosage: 1000 MG, QD. During the same period patient was treated with CYCLOPHOSPHAMIDE, AZATHIOPRINE, CORTICOSTEROIDS, CYCLOSPORINE, GANCICLOVIR. Patient was hospitalized. Patient recovered.Mabthera Side Effects Report #5676371-5
Mabthera side effect was reported by a Physician from UNITED KINGDOM on Mar 11, 2008. Male patient, child 12 years of age, was diagnosed with systemic lupus erythematosus and was treated with Mabthera. After drug was administered, patient experienced the following side effects: bone marrow failure, chest pain
, hypotension, pyrexia. Mabthera dosage: 1000 MG, QD. During the same period patient was treated with CYCLOPHOSPHAMIDE, AZATHIOPRINE, CORTICOSTEROIDS, CYCLOSPORINE, GANCICLOVIR. Patient was hospitalized. Patient recovered.Mabthera Side Effects Report #5694633-2
Mabthera side effect was reported by a Physician from UNITED KINGDOM on Mar 24, 2008. Male patient, child 12 years of age, was diagnosed with systemic lupus erythematosus and was treated with Mabthera. After drug was administered, patient experienced the following side effects: bone marrow failure, chest pain
, hypotension, pyrexia. Mabthera dosage: 1000 MG, QD. During the same period patient was treated with CYCLOPHOSPHAMIDE, AZATHIOPRINE, CORTICOSTEROIDS, CYCLOSPORINE, GANCICLOVIR. Patient was hospitalized. Patient recovered.Mabthera Side Effects Report #5700651-8
Mabthera side effect was reported by a Physician from UNITED KINGDOM on Mar 29, 2008. Male patient, child 12 years of age, was diagnosed with systemic lupus erythematosus and was treated with Mabthera. After drug was administered, patient experienced the following side effects: bone marrow failure, chest pain
, hypotension, pyrexia. Mabthera dosage: 1000 MG, QD. During the same period patient was treated with CYCLOPHOSPHAMIDE, AZATHIOPRINE, CORTICOSTEROIDS, CYCLOSPORINE, GANCICLOVIR. Patient was hospitalized. Patient died on 03/27/2008.Mabthera Side Effects Report #6023407-8
Mabthera side effect was reported by a Physician from UNITED KINGDOM on Dec 16, 2008. Female patient, 75 years of age, was diagnosed with rheumatoid arthritis
and was treated with Mabthera. After drug was administered, patient experienced the following side effects: bone marrow failure. Mabthera dosage: unknown. During the same period patient was treated with FLUINDIONE, PENTOXIFYLLINE, METHOTREXATE, COVERSYL. Patient was hospitalized. Patient died.Mabthera Side Effects Report #5522807-X
Mabthera side effect was reported by a Physician from PORTUGAL on Nov 08, 2007. Female patient, 66 years of age, weighting 99.21 lb, was diagnosed with rheumatoid arthritis
, inflammation, cardiac failure and was treated with Mabthera. After drug was administered, patient experienced the following side effects: bone marrow failure, pancytopenia. Mabthera dosage: unknown. During the same period patient was treated with METHOTREXATE, PREXIGE, FOLIC ACID, MEDROL, FUROSEMIDE. Patient was hospitalized and became disabled. Patient recovered.Mabthera Side Effects Report #5975945-1
Mabthera side effect was reported by a Physician from UNITED KINGDOM on Nov 18, 2008. Female patient was diagnosed with rheumatoid arthritis
and was treated with Mabthera. After drug was administered, patient experienced the following side effects: bone marrow failure. Mabthera dosage: unknown. During the same period patient was treated with FLUINDIONE, PENTOXIFYLLINE, METHOTREXATE, COVERSYL. Patient died.Mabthera Side Effects Report #4978807-1
Mabthera side effect was reported by a Physician from SWITZERLAND on Apr 03, 2006. Female patient, 74 years of age, weighting 101.4 lb, was diagnosed with non-hodgkin's lymphoma and was treated with Mabthera. After drug was administered, patient experienced the following side effects: bone marrow failure, chronic lymphocytic leukaemia transformation, splenomegaly. Mabthera dosage: 500 MG, INTRAVENOUS. Patient recovered.
Mabthera Side Effects Report #5346536-0
Mabthera side effect was reported by a Health Professional from FRANCE on May 30, 2007. Male patient, 57 years of age, was diagnosed with non-hodgkin's lymphoma and was treated with Mabthera. After drug was administered, patient experienced the following side effects: bone marrow failure. Mabthera dosage: unknown. During the same period patient was treated with METHOTREXATE, DOXORUBICIN, VINDESINE, ENDOXAN, BLEOMYCIN. Patient was hospitalized. Patient recovered.
Mabthera Side Effects Report #5047234-3
Mabthera side effect was reported by a Consumer or non-health professional from FRANCE on June 21, 2006. Female patient, 49 years of age, weighting 216.1 lb, was diagnosed with non-hodgkin's lymphoma and was treated with Mabthera. After drug was administered, patient experienced the following side effects: aphasia
, bone marrow failure, brain compression, candida sepsis, cerebral haematoma, enterobacter sepsis, hemiparesis, hyperthermia, pancytopenia. Mabthera dosage: unknown. During the same period patient was treated with METHOTREXATE, DOXORUBICIN, ETOPOPHOS, CYCLOPHOSPHAMIDE, CYTARABINE. Patient died on 05/16/2006.Mabthera Side Effects Report #5090740-6
Mabthera side effect was reported by a Physician from SPAIN on Aug 10, 2006. Female patient, 49 years of age, weighting 105.8 lb, was diagnosed with non-hodgkin's lymphoma and was treated with Mabthera. After drug was administered, patient experienced the following side effects: aplastic anaemia, bone marrow failure, granulocytopenia, pancytopenia, pyrexia. Mabthera dosage: 375 MG, Q28D, INTRAVENOUS. During the same period patient was treated with CYCLOPHOSPHAMIDE, FLUDARABINE, SEPTRA, ACYCLOVIR, SINTROM. Patient recovered.
Mabthera Side Effects Report #5145649-6
Mabthera side effect was reported by a Physician from SPAIN on Oct 24, 2006. Female patient, 49 years of age, weighting 105.8 lb, was diagnosed with non-hodgkin's lymphoma and was treated with Mabthera. After drug was administered, patient experienced the following side effects: aplastic anaemia, bone marrow failure, bronchopulmonary aspergillosis. Mabthera dosage: 375 MG, Q28D, INTRAVENOUS. During the same period patient was treated with CYCLOPHOSPHAMIDE, FLUDARABINE PHOSPHATE, SEPTRA, ACYCLOVIR, SINTROM. Patient recovered.
Mabthera Side Effects Report #4847455-6
Mabthera side effect was reported by a Physician from GERMANY on Nov 22, 2005. Female patient, 40 years of age, weighting 119.0 lb, was diagnosed with non-hodgkin's lymphoma and was treated with Mabthera. After drug was administered, patient experienced the following side effects: alveolitis, blood lactate dehydrogenase decreased, bone marrow failure, cholelithiasis, hilar lymphadenopathy, lung consolidation, pneumocystis jiroveci pneumonia, refusal of treatment by patient, respiratory failure. Mabthera dosage: 375 MG/KG, 1/WEEK, INTRAVENOUS. During the same period patient was treated with CYCLOPHOSPHAMIDE, METHOTREXATE, FLUOROURACIL. Patient was hospitalized. Patient recovered.
Mabthera Side Effects Report #4891923-8
Mabthera side effect was reported by a Physician from GERMANY on Jan 09, 2006. Female patient, 40 years of age, weighting 119.0 lb, was diagnosed with non-hodgkin's lymphoma and was treated with Mabthera. After drug was administered, patient experienced the following side effects: blood cholesterol increased, bone marrow failure, candidiasis, cholelithiasis, leukopenia, lymphadenopathy, neutrophil percentage increased, platelet count decreased, pneumocystis jiroveci pneumonia. Mabthera dosage: 375 MG/KG, 1/WEEK, INTRAVENOUS. During the same period patient was treated with CYCLOPHOSPHAMIDE, METHOTREXATE, FLUOROURACIL. Patient was hospitalized. Patient recovered.
Mabthera Side Effects Report #5271365-6
Mabthera side effect was reported by a Health Professional from FRANCE on Mar 14, 2007. Male patient, 81 years of age, was diagnosed with mantle cell lymphoma stage iv and was treated with Mabthera. After drug was administered, patient experienced the following side effects: bone marrow failure, pyrexia. Mabthera dosage: unknown. During the same period patient was treated with GEMZAR, ELOXATIN. Patient was hospitalized. Patient recovered.
Mabthera Side Effects Report #5377794-4
Mabthera side effect was reported by a Physician from FRANCE on June 27, 2007. Male patient, 26 years of age, was diagnosed with lymphoma
and was treated with Mabthera. After drug was administered, patient experienced the following side effects: bone marrow failure. Mabthera dosage: unknown. Patient recovered.Mabthera Side Effects Report #5552116-4
Mabthera side effect was reported by a Health Professional from UNITED KINGDOM on Dec 04, 2007. Male patient was diagnosed with lymphoma
and was treated with Mabthera. After drug was administered, patient experienced the following side effects: bone marrow failure. Mabthera dosage: 606.5 MG, QD. During the same period patient was treated with METHOTREXATE, ENDOXAN, DOXORUBICIN, BLEOMYCIN, ELDISINE. Patient was hospitalized. Patient recovered.Mabthera Side Effects Report #5647453-9
Mabthera side effect was reported by a Physician from UNITED KINGDOM on Feb 20, 2008. Male patient was diagnosed with lymphoma
and was treated with Mabthera. After drug was administered, patient experienced the following side effects: bone marrow failure. Mabthera dosage: unknown. During the same period patient was treated with ONCOVIN, DOXORUBICIN, ENDOXAN. Patient was hospitalized. Patient recovered.Mabthera Side Effects Report #5802274-9
Mabthera side effect was reported by a Health Professional from UNITED KINGDOM on June 27, 2008. Female patient, 58 years of age, was diagnosed with lymphocytic leukaemia and was treated with Mabthera. After drug was administered, patient experienced the following side effects: bone marrow failure. Mabthera dosage: 570 MG, UNK. Patient recovered.
Mabthera Side Effects Report #5912644-6
Mabthera side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on Sept 23, 2008. Male patient, 59 years of age, was diagnosed with diffuse large b-cell lymphoma and was treated with Mabthera. After drug was administered, patient experienced the following side effects: bone marrow failure. Mabthera dosage: 600 MG, UNK. During the same period patient was treated with CYCLOPHOSPHAMIDE, DOXORUBICIN, PREDNISONE, VINCRISTINE. Patient recovered.
Mabthera Side Effects Report #5937729-X
Mabthera side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on Oct 22, 2008. Male patient, 59 years of age, was diagnosed with diffuse large b-cell lymphoma and was treated with Mabthera. After drug was administered, patient experienced the following side effects: bone marrow failure. Mabthera dosage: 600 MG, UNK. During the same period patient was treated with CYCLOPHOSPHAMIDE, DOXORUBICIN, PREDNISONE, VINCRISTINE. Patient recovered.
Mabthera Side Effects Report #4961436-3
Mabthera side effect was reported by a Physician from FRANCE on Mar 20, 2006. Female patient, 40 years of age, weighting 209.4 lb, was diagnosed with diffuse large b-cell lymphoma and was treated with Mabthera. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, anaemia, bone marrow failure, cardiac arrest
, cardiac failure, coagulopathy, deep vein thrombosis , dialysis , gastroenteritis . Mabthera dosage: unknown. During the same period patient was treated with DOXORUBICIN HYDROCHLORIDE, ENDOXAN, VINDESINE, BLEOMYCIN SULPHATE, METHOTREXATE, BACTRIM DS. Patient recovered.Mabthera Side Effects Report #4961632-5
Mabthera side effect was reported by a Consumer or non-health professional from FRANCE on Mar 20, 2006. Female patient, 40 years of age, weighting 209.4 lb, was diagnosed with diffuse large b-cell lymphoma and was treated with Mabthera. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, bone marrow failure, cardiac arrest
, cardiac failure, coagulopathy, deep vein thrombosis , dialysis , gastroenteritis , hypovolaemic shock. Mabthera dosage: unknown. During the same period patient was treated with BLEOMYCIN SULPHATE, VINDESINE, DOXORUBICINE, ENDOXAN, METHOTREXATE, BACTRIM DS, CEFIXIME. Patient recovered.Mabthera Side Effects Report #4978806-X
Mabthera side effect was reported by a Physician from FRANCE on Apr 05, 2006. Female patient, 40 years of age, weighting 209.4 lb, was diagnosed with diffuse large b-cell lymphoma and was treated with Mabthera. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, anaemia, axillary vein thrombosis, bacillus infection, bone marrow failure, cardiac arrest
, cardiac failure, coagulopathy, deep vein thrombosis . Mabthera dosage: unknown. During the same period patient was treated with BLEOMYCIN SULPHATE, VINDESINE, DOXORUBICIN HYDROCHLORIDE, ENDOXAN, METHOTREXATE, BACTRIM DS, CEFIXIME. Patient recovered.Mabthera Side Effects Report #4978864-2
Mabthera side effect was reported by a Physician from FRANCE on Apr 05, 2006. Female patient, 40 years of age, weighting 209.4 lb, was diagnosed with diffuse large b-cell lymphoma and was treated with Mabthera. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, anaemia, axillary vein thrombosis, blood pressure abnormal, bone marrow failure, cardiac arrest
, cardiac failure, coagulopathy, deep vein thrombosis . Mabthera dosage: unknown. During the same period patient was treated with DOXORUBICIN, ENDOXAN, VINDESINE, BLEOMYCIN, METHOTREXATE, BACTRIMTE. Patient died on 03/08/2006.Mabthera Side Effects Report #4998613-1
Mabthera side effect was reported by a Physician from FRANCE on Apr 26, 2006. Female patient, 40 years of age, weighting 209.4 lb, was diagnosed with diffuse large b-cell lymphoma and was treated with Mabthera. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, bone marrow failure, cardiac arrest
, cardiac failure, coagulopathy, deep vein thrombosis , dialysis , dyspnoea. Mabthera dosage: unknown. During the same period patient was treated with BLEOMYCINE, VINDESINE, DOXORUBICIN HYDROCHLORIDE, CYCLOPHOSPHAMIDE, METHOTREXATE, BACTRIM DS, CEFIXIME. Patient died.Mabthera Side Effects Report #5006746-9
Mabthera side effect was reported by a Physician from FRANCE on May 05, 2006. Female patient, 40 years of age, weighting 209.4 lb, was diagnosed with diffuse large b-cell lymphoma and was treated with Mabthera. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, bone marrow failure, cardiac arrest
, cardiac failure, cardiovascular disorder, coagulopathy, deep vein thrombosis , dialysis , dyspnoea. Mabthera dosage: unknown. During the same period patient was treated with DOXORUBICIN HYDROCHLORIDE, CYCLOPHOSPHAMIDE, VINDESINE, BLEOMYCIN SULPHATE, METHOTREXATE, BACTRIM DS. Patient died on 03/08/2006.Mabthera Side Effects Report #5014378-1
Mabthera side effect was reported by a Physician from FRANCE on May 16, 2006. Female patient, 40 years of age, weighting 209.4 lb, was diagnosed with diffuse large b-cell lymphoma and was treated with Mabthera. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, axillary vein thrombosis, blood culture positive, bone marrow failure, cardiac arrest
, cardiac failure, coagulopathy, deep vein thrombosis , dialysis . Mabthera dosage: unknown. During the same period patient was treated with BLEOMYCIN SULPHATE, VINDESINE, DOXORUBICIN HYDROCHLORIDE, ENDOXAN, METHOTREXATE, BACTRIM DS, CEFIXIME. Patient died on 03/08/2006.Mabthera Side Effects Report #6078348-7
Mabthera side effect was reported by a Physician from UNITED KINGDOM on Jan 29, 2009. Male patient, 64 years of age, was diagnosed with chronic lymphocytic leukaemia and was treated with Mabthera. After drug was administered, patient experienced the following side effects: bone marrow failure. Mabthera dosage: unknown. During the same period patient was treated with FLUDARABINE PHOSPHATE, CYCLOPHOSPHAMIDE. Patient was hospitalized. Patient recovered.
Mabthera Side Effects Report #4821956-9
Mabthera side effect was reported by a Health Professional from GERMANY on Oct 25, 2005. Male patient, 58 years of age, weighting 238.1 lb, was diagnosed with chronic lymphocytic leukaemia and was treated with Mabthera. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, blood alkaline phosphatase increased, bone marrow failure, bone marrow toxicity, gamma-glutamyltransferase increased, hyperhidrosis, leukopenia, platelet count decreased, splenomegaly. Mabthera dosage: 500 MG,. During the same period patient was treated with FLUDARABINE, CYCLOPHOSPHAMIDE, COTRIMTE, FUROSEMIDE, ESIDRIX. Patient recovered.
Mabthera Side Effects Report #4825487-1
Mabthera side effect was reported by a Physician from GERMANY on Nov 01, 2005. Male patient, 58 years of age, weighting 238.1 lb, was diagnosed with chronic lymphocytic leukaemia and was treated with Mabthera. After drug was administered, patient experienced the following side effects: blood alkaline phosphatase increased, bone marrow failure, bone marrow toxicity, gamma-glutamyltransferase increased, hyperhidrosis, leukopenia, spleen disorder, splenomegaly, therapeutic response decreased. Mabthera dosage: 500 MG. During the same period patient was treated with FLUDARABINE PHOSPHATE, CYCLOPHOSPHAMIDE, COTRIMTE, FUROSEMIDE, ESIDRIX, LEVOFLOXACIN, AMPHOMORONAL. Patient recovered.
Mabthera Side Effects Report #5802414-1
Mabthera side effect was reported by a Physician from UNITED KINGDOM on May 27, 2008. Female patient, weighting 165.3 lb, was diagnosed with chronic lymphocytic leukaemia and was treated with Mabthera. After drug was administered, patient experienced the following side effects: bone marrow failure, pancytopenia, pyrexia. Mabthera dosage: 671 MG, UNK. During the same period patient was treated with TAVEGYL, ACETAMINOPHEN, FLUDARABINE PHOSPHATE, ENDOXAN. Patient was hospitalized. Patient recovered.
Mabthera Side Effects Report #6023622-3
Mabthera side effect was reported by a Pharmacist from GERMANY on Dec 22, 2008. Female patient, 65 years of age, was diagnosed with b-cell lymphoma, bone marrow disorder and was treated with Mabthera. After drug was administered, patient experienced the following side effects: aspergillosis, bone marrow failure, fungal infection
. Mabthera dosage: 375 MG/M2, UNK. During the same period patient was treated with CYCLOPHOSPHAMIDE, PREDNISONE, BENDAMUSTINE. Patient recovered.Mabthera Side Effects Report #4815714-9
Mabthera side effect was reported by a Physician from GERMANY on Oct 17, 2005. Male patient, 63 years of age, weighting 189.6 lb, was diagnosed with b-cell lymphoma and was treated with Mabthera. After drug was administered, patient experienced the following side effects: bone marrow failure, cardiovascular insufficiency, cerebral haemorrhage, haematotoxicity, mucosal inflammation, pancytopenia, respiratory depression. Mabthera dosage: 712 MG, SINGLE, INTRAVENOUS. During the same period patient was treated with CYCLOPHOSPHAMIDE, DOXORUBICIN, VINCRISTINE, PREDNISONE, ADRIBLASTIN. Patient was hospitalized. Patient died on 09/01/2005.
Mabthera Side Effects Report #5014381-1
Mabthera side effect was reported by a Physician from GERMANY on Oct 17, 2005. Male patient, 63 years of age, weighting 189.6 lb, was diagnosed with b-cell lymphoma and was treated with Mabthera. After drug was administered, patient experienced the following side effects: blood lactate dehydrogenase increased, blood urea increased, bone marrow failure, cardiovascular insufficiency, cerebral haemorrhage, fluid intake reduced, haematotoxicity, mucosal inflammation. Mabthera dosage: 712 MG, SINGLE, INTRAVENOUS. During the same period patient was treated with CYCLOPHOSPHAMIDE, DOXORUBICIN, VINCRISTINE, PREDNISONE, ADRIBLASTIN. Patient was hospitalized. Patient recovered.
Mabthera Side Effects Report #5513509-4
Mabthera side effect was reported by a Physician from PORTUGAL on Oct 31, 2007. Female patient, 66 years of age, weighting 99.21 lb, was diagnosed with rheumatoid arthritis
, atrial fibrillation and was treated with Mabthera. After drug was administered, patient experienced the following side effects: bone marrow failure, pancytopenia. Mabthera dosage: unknown. During the same period patient was treated with METHOTREXATE, FOLIC ACID, METHYLPREDNISOLONE, FUROSEMIDE, WARFARIN. Patient was hospitalized and became disabled. Patient recovered.