Methotrexate and convulsion 
Methotrexate and convulsion Patient Reports March 15, 2010
Methotrexate Side Effects Report #5481798-0
Methotrexate side effect was reported by a Consumer or non-health professional from on Oct 02, 2007. Male patient, child 9 years of age, was diagnosed with t-cell type acute leukaemia and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: abdominal pain
, confusional state, constipation , convulsion, dizziness , headache , hypertension, mental status changes. Methotrexate dosage: unknown. During the same period patient was treated with PREDNISONE, CYTARABINE, VINCRISTINE, DEZROXOZANE, DOXORUBICIN. Patient was hospitalized. Patient recovered.Methotrexate Side Effects Report #5357275-4
Methotrexate side effect was reported by a Health Professional from JAPAN on May 28, 2007. Male patient, 25 years of age, weighting 150.6 lb, was diagnosed with t-cell type acute leukaemia and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: blood bilirubin increased, cerebral haemorrhage, convulsion, hemiparesis, superior sagittal sinus thrombosis. Methotrexate dosage: 15 MG, UNK, INTRATHECAL. During the same period patient was treated with PREDNISOLONE, CYTRABIN, VINCRISTINE, CYCLOPHOSPHAMIDE, MITOXANTRONE. Patient was hospitalized. Patient recovered.
Methotrexate Side Effects Report #5656139-6
Methotrexate side effect was reported by a Health Professional from UNITED STATES on Feb 20, 2008. Male patient, 18 years of age, was diagnosed with t-cell type acute leukaemia and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: affect lability, cerebrovascular accident, convulsion, encephalopathy, leukoencephalopathy, nuclear magnetic resonance imaging brain abnormal. Methotrexate dosage: unknown. Patient recovered.
Methotrexate Side Effects Report #5229974-6
Methotrexate side effect was reported by a Consumer or non-health professional from JAPAN on Jan 31, 2007. Female patient, 43 years of age, was diagnosed with stem cell transplant and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: confusional state, convulsion, csf virus identified, graft versus host disease, human herpes virus 6 serology positive, meningoencephalitis herpetic, nuclear magnetic resonance imaging brain abnormal. Methotrexate dosage: unknown. During the same period patient was treated with CYCLOSPORINE. Patient died.
Methotrexate Side Effects Report #4560232-9
Methotrexate side effect was reported by a Pharmacist from on Jan 20, 2005. Female patient, 63 years of age, weighting 130.1 lb, was diagnosed with spondylitis and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, cardiac failure congestive, cardio-respiratory arrest, convulsion, interstitial lung disease, pneumonia
, pneumonitis, renal failure acute. Methotrexate dosage: 15MG WEEKLY ORAL. During the same period patient was treated with AYGESTIN, ASPIRIN, PREMARIN, FOLIC ACID, NEURONTIN, PROTONIX, SKELAXIN, PERCOCET. Patient was hospitalized. Patient died on 10/22/2004.Methotrexate Side Effects Report #5087924-X
Methotrexate side effect was reported by a Health Professional from UNITED STATES on Aug 23, 2006. Female patient, weighting 152.0 lb, was diagnosed with rheumatoid arthritis
and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: convulsion, respiratory arrest. Methotrexate dosage: 20 MG A WEEK PO. During the same period patient was treated with ENBREL, HYDROXYCHLOROQUINE SULPHATE, SULFASALAZINE, PREDNISONE, LISINOPRIL, ROBITTUSIN AC. Patient died on 05/24/2006.Methotrexate Side Effects Report #5034901-0
Methotrexate side effect was reported by a Health Professional from UNITED STATES on June 23, 2006. Female patient, weighting 152.0 lb, was diagnosed with rheumatoid arthritis
and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: convulsion, respiratory arrest. Methotrexate dosage: 20 MG A WEEK PO. During the same period patient was treated with ENBREL, PREDNISONE, LISINOPRIL, ROBITTUSIN AC, HYDROXYCHLOROQUINE SULPHATE, SULFASALAZINE. Patient died on 05/24/2006.Methotrexate Side Effects Report #5481797-9
Methotrexate side effect was reported by a Consumer or non-health professional from on Oct 02, 2007. Male patient, child 10 years of age, was diagnosed with osteosarcoma metastatic and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: altered state of consciousness, aplasia, asthenia, convulsion, encephalitis
, hypotension, neutropenia, pyrexia, rash vesicular. Methotrexate dosage: unknown. During the same period patient was treated with DOXORUBICIN. Patient was hospitalized. Patient recovered.Methotrexate Side Effects Report #4615258-3
Methotrexate side effect was reported by a Consumer or non-health professional from on Mar 03, 2005. Male patient, 67 years of age, was diagnosed with non-hodgkin's lymphoma and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: brain oedema, cerebral haematoma, convulsion, disease progression, grand mal convulsion, headache
, hemiparesis, meningeal disorder, nausea . Methotrexate dosage: unknown. Patient died.Methotrexate Side Effects Report #5617252-2
Methotrexate side effect was reported by a Consumer or non-health professional from TURKEY on Jan 23, 2008. Male patient, child 6 years of age, was diagnosed with non-hodgkin's lymphoma and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: aphasia
, cerebral haematoma, convulsion, hemiparesis, loss of consciousness. Methotrexate dosage: unknown. During the same period patient was treated with PREDNISONE, CYTARABINE, CYCLOPHOSPHAMIDE, IFOSFAMIDE, ETOPOSIDE, DOXORUBICIN, VINCRISTINE SULPHATE, FOLINIC ACID. Patient died.Methotrexate Side Effects Report #5633427-0
Methotrexate side effect was reported by a Consumer or non-health professional from TURKEY on Feb 20, 2008. Male patient, child 6 years of age, was diagnosed with non-hodgkin's lymphoma and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: aphasia
, cerebral haematoma, convulsion, hemiparesis, loss of consciousness, malignant neoplasm progression, non-hodgkin's lymphoma. Methotrexate dosage: unknown. During the same period patient was treated with PREDNISONE, CYTARABINE, CYCLOPHOSPHAMIDE, IFOSFAMIDE, ETOPOSIDE, DOXORUBICIN, VINCRISTINE SULPHATE, FOLINIC ACID. Patient died.Methotrexate Side Effects Report #5670627-8
Methotrexate side effect was reported by a Pharmacist from UNITED STATES on Mar 14, 2008. Male patient, weighting 36.16 lb, was diagnosed with metabolic alkalosis and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: cardiac arrest
, convulsion, gaze palsy, hypokalaemia, hypomagnesaemia, hypophosphataemia, ill-defined disorder, metabolic alkalosis. Methotrexate dosage: 3500 MG X1 IV DRIP. During the same period patient was treated with BICARBONATE. Patient was hospitalized. Patient recovered.Methotrexate Side Effects Report #5533827-3
Methotrexate side effect was reported by a Consumer or non-health professional from GERMANY on Nov 14, 2007. Female patient, child 9 years of age, was diagnosed with medulloblastoma and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: convulsion, glioma, intracranial pressure increased, nervous system disorder. Methotrexate dosage: unknown. Patient died.
Methotrexate Side Effects Report #5531347-3
Methotrexate side effect was reported by a Consumer or non-health professional from GERMANY on Nov 14, 2007. Female patient, 16 years of age, was diagnosed with medulloblastoma and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: convulsion, glioma, stress
. Methotrexate dosage: unknown. During the same period patient was treated with CISPLATIN, CARBOPLATIN, CYCLOPHOSPHAMIDE, VINCRISTINE, ETOPOSIDE, CYTARABINE. Patient died.Methotrexate Side Effects Report #4568015-0
Methotrexate side effect was reported by a Consumer or non-health professional from on Jan 28, 2005. Female patient, 69 years of age, was diagnosed with lymphoma
and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: bone marrow depression, cerebellar syndrome, confusional state, convulsion, hypotonia, loss of consciousness, mucosal inflammation. Methotrexate dosage: 1.98 MG TOTAL. Patient recovered.Methotrexate Side Effects Report #4778845-8
Methotrexate side effect was reported by a Health Professional from SWEDEN on Sept 06, 2005. Female patient, child 11 years of age, was diagnosed with leukaemia and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: blood creatinine increased, blood pressure increased, convulsion. Methotrexate dosage: 9600 MG IV. During the same period patient was treated with GLUCOSE, ZOFRAN, KYTRIL. Patient was hospitalized. Patient recovered.
Methotrexate Side Effects Report #4658105-6
Methotrexate side effect was reported by a Physician from on Apr 21, 2005. Male patient was diagnosed with leukaemia, acute lymphocytic leukaemia and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: convulsion. Methotrexate dosage: unknown. During the same period patient was treated with MERCAPTOPURINE, CYTARABINE, HYDROCORTISONE. Patient recovered.
Methotrexate Side Effects Report #4970859-8
Methotrexate side effect was reported by a Health Professional from NETHERLANDS on Mar 30, 2006. Female patient, child 9 years of age, was diagnosed with juvenile arthritis and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: balance disorder, convulsion, hemiparesis. Methotrexate dosage: unknown. During the same period patient was treated with INDOMETHACIN, PREDNISONE. Patient recovered.
Methotrexate Side Effects Report #5512616-X
Methotrexate side effect was reported by a Physician from SOUTH AFRICA on Oct 30, 2007. Female patient, weighting 235.9 lb, was diagnosed with ill-defined disorder and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: balance disorder, convulsion. Methotrexate dosage: unknown. During the same period patient was treated with PREXUM, PREDNISONE, NAFASOL, PURESIS. Patient recovered.
Methotrexate Side Effects Report #4802945-7
Methotrexate side effect was reported by a Consumer or non-health professional from UNITED STATES on Oct 17, 2005. Male patient, weighting 129.0 lb, was diagnosed with glioblastoma multiforme and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: brain neoplasm, condition aggravated, convulsion, coordination abnormal, deep vein thrombosis
, disease progression. Methotrexate dosage: unknown. During the same period patient was treated with TEMODAR. Patient was hospitalized. Patient died.Methotrexate Side Effects Report #6035088-8
Methotrexate side effect was reported by a Consumer or non-health professional from on Jan 07, 2009. Female patient, 18 years of age, was diagnosed with central nervous system leukaemia, bone marrow conditioning regimen, prophylaxis against graft versus host disease, oliguria, cardiac failure congestive and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: anuria, azotaemia, blood creatinine increased, cardiac failure congestive, central nervous system leukaemia, convulsion, graft versus host disease, leukaemia recurrent, oliguria. Methotrexate dosage: unknown. During the same period patient was treated with CYCLOPHOSPHAMIDE, CYCLOSPORINE, CYTARABINE, HYDROCORTISONE, LOOP DIURETIC, LOOP DIURETIC, DOPAMINE. Patient died.
Methotrexate Side Effects Report #5110814-0
Methotrexate side effect was reported by a Physician from KENYA on Sept 05, 2006. Male patient, child 8 years of age, was diagnosed with burkitt's lymphoma and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: anorexia, arthralgia, asthenia, blood creatinine decreased, blood potassium decreased, convulsion, dehydration, diarrhoea, haemoglobin decreased. Methotrexate dosage: 20 MG/M2 PU. During the same period patient was treated with VINCRISTINE, CYCLOPHOSPHAMIDE, PREDNISOLONE. Patient was hospitalized. Patient recovered.
Methotrexate Side Effects Report #5212619-9
Methotrexate side effect was reported by a Consumer or non-health professional from UNITED STATES on Apr 26, 2006. Male patient, 24 years of age, weighting 168.0 lb, was diagnosed with burkitt's lymphoma and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: convulsion. Methotrexate dosage: 12MG/INTRATHECAL. During the same period patient was treated with ZOFREN. Patient recovered.
Methotrexate Side Effects Report #4764836-X
Methotrexate side effect was reported by a Consumer or non-health professional from BRAZIL on Aug 24, 2005. Female patient, 51 years of age, was diagnosed with breast cancer metastatic and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: chest pain
, convulsion, malaise. Methotrexate dosage: 65 MILLIGRAM INTRAVENOUS (NOS). During the same period patient was treated with CYCLOPHOSPHAMIDE, FLUOROURACIL, CAPTOPRIL, PROPRANOLOL. Patient died.Methotrexate Side Effects Report #4846216-1
Methotrexate side effect was reported by a Consumer or non-health professional from BRAZIL on Nov 16, 2005. Female patient, 51 years of age, was diagnosed with breast cancer metastatic and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: chest pain
, convulsion, dyspnoea, malaise. Methotrexate dosage: 65 MILLIGRAM INTRAVENOUS NOS. During the same period patient was treated with CYCLOPHOSPHAMIDE, FLUOROURACIL, CAPTOPRIL, PROPRANOLOL. Patient died.Methotrexate Side Effects Report #4952225-4
Methotrexate side effect was reported by a Consumer or non-health professional from BRAZIL on Mar 10, 2006. Female patient, 51 years of age, was diagnosed with breast cancer metastatic and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: breast cancer female, convulsion, malaise, metastases to liver, metastases to lung, myocardial infarction. Methotrexate dosage: 65 MILLIGRAM INTRAVENOUS (NOS). During the same period patient was treated with CYCLOPHOSPHAMIDE, FLUOROURACIL, CAPTOPRIL, PROPRANOLOL. Patient died.
Methotrexate Side Effects Report #5285403-8
Methotrexate side effect was reported by a Consumer or non-health professional from GERMANY on Mar 12, 2007. Female patient, child 9 years of age, was diagnosed with brain neoplasm malignant and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: convulsion, glioma, intracranial pressure increased, nervous system disorder. Methotrexate dosage: unknown. Patient died.
Methotrexate Side Effects Report #5266531-X
Methotrexate side effect was reported by a Consumer or non-health professional from on Mar 12, 2007. Female patient, 16 years of age, weighting 110.2 lb, was diagnosed with bone sarcoma and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: anaemia, blood creatinine increased, convulsion, haemodialysis, headache
, hypertension, mucosal inflammation. Methotrexate dosage: unknown. During the same period patient was treated with ETOPOSIDE, IFOSFAMIDE. Patient was hospitalized. Patient recovered.Methotrexate Side Effects Report #5368535-5
Methotrexate side effect was reported by a Health Professional from FRANCE on June 04, 2007. Female patient, 16 years of age, was diagnosed with bone sarcoma and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: blood pressure increased, convulsion, cytolytic hepatitis, mucosal inflammation, renal failure, renal tubular disorder, thrombocytopenia. Methotrexate dosage: unknown. During the same period patient was treated with DANTROLENE, ONDANESTRON, METHYLPREDNISOLONE, NALBUPHINE. Patient recovered.
Methotrexate Side Effects Report #5133205-5
Methotrexate side effect was reported by a Physician from FRANCE on Oct 06, 2006. Female patient, 16 years of age, was diagnosed with bone sarcoma, analgesic effect and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: blood pressure increased, convulsion, cytolytic hepatitis, mucosal inflammation, renal failure, renal tubular disorder, thrombocytopenia. Methotrexate dosage: unknown. During the same period patient was treated with ETOPOSIDE, IFOSFAMIDE, ONDANSETRON, DANTROLENE. Patient recovered.
Methotrexate Side Effects Report #5157977-9
Methotrexate side effect was reported by a Consumer or non-health professional from on Nov 15, 2006. Female patient, 16 years of age, was diagnosed with bone sarcoma, analgesic effect, prophylaxis of nausea and vomiting and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: blood pressure increased, convulsion, cytolytic hepatitis, mucosal inflammation, renal failure, renal tubular disorder, thrombocytopenia. Methotrexate dosage: unknown. During the same period patient was treated with DANTROLENE, ETOPOSIDE, IFOSFAMIDE, ONDANSETRON, METHYLPREDNISOLONE, NALBUPHINE. Patient recovered.
Methotrexate Side Effects Report #5573216-9
Methotrexate side effect was reported by a Consumer or non-health professional from FRANCE on Dec 05, 2007. Female patient, 16 years of age, was diagnosed with bone sarcoma, analgesia and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: anaemia, blood pressure increased, convulsion, cytolytic hepatitis, headache
, mucosal inflammation, neutropenia. Methotrexate dosage: unknown. During the same period patient was treated with DANTROLENE, ONDANSETRON, METHYLPREDNISOLONE, NALBUPHINE. Patient recovered.Methotrexate Side Effects Report #4737028-8
Methotrexate side effect was reported by a Physician from KUWAIT on June 17, 2005. Male patient, child 10 years of age, was diagnosed with bone sarcoma and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: convulsion, depressed level of consciousness, diplopia, disorientation, eye movement disorder. Methotrexate dosage: unknown. During the same period patient was treated with CISPLATIN, ADRIAMYCIN PFS, LEUCOVORIN CALCIUM. Patient recovered.
Methotrexate Side Effects Report #5322909-7
Methotrexate side effect was reported by a Physician from UNITED STATES on Jan 08, 2007. Female patient, weighting 172.0 lb, was diagnosed with bone sarcoma and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: convulsion. Methotrexate dosage: unknown. Patient was hospitalized. Patient recovered.
Methotrexate Side Effects Report #4675645-4
Methotrexate side effect was reported by a Consumer or non-health professional from on May 17, 2005. Male patient, 54 years of age, weighting 165.3 lb, was diagnosed with bone marrow transplant
and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: aphasia , convulsion, disturbance in attention, dysarthria, dysphagia, electroencephalogram abnormal, facial palsy, glasgow coma scale abnormal, hemiparesis. Methotrexate dosage: unknown. During the same period patient was treated with SPECIAFOLDINE, MAG, ROVAMYCINE, TRIFLUCAN, TENORDATE, LEXOMIL, NEORAL. Patient was hospitalized. Patient recovered.Methotrexate Side Effects Report #4658107-X
Methotrexate side effect was reported by a Physician from on Apr 21, 2005. Female patient was diagnosed with b-cell type acute leukaemia and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: convulsion. Methotrexate dosage: unknown. During the same period patient was treated with MERCAPTOPURINE, CYTARABINE, HYDROCORTISONE. Patient recovered.
Methotrexate Side Effects Report #5481799-2
Methotrexate side effect was reported by a Consumer or non-health professional from on Oct 02, 2007. Female patient, child 4 years of age, was diagnosed with b precursor type acute leukaemia, convulsion, hypertension and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: convulsion, hypertension, reversible posterior leukoencephalopathy syndrome. Methotrexate dosage: unknown. During the same period patient was treated with PREDNISONE, VINCRISTINE, DAUNORUBICIN, ELSPAR, FOSPHENYTOIN, LEVETIRACETAM, AMLODIPINE. Patient was hospitalized. Patient recovered.
Methotrexate Side Effects Report #4911113-X
Methotrexate side effect was reported by a Consumer or non-health professional from on Jan 31, 2006. Male patient, child 9 years of age, was diagnosed with acute lymphocytic leukaemia, convulsion and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, coma, convulsion, hepatotoxicity, neurotoxicity. Methotrexate dosage: unknown. During the same period patient was treated with DIAZEPAM. Patient recovered.
Methotrexate Side Effects Report #4658301-8
Methotrexate side effect was reported by a Physician from on Apr 21, 2005. Female patient, child 8 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: coma, convulsion, leukoencephalopathy. Methotrexate dosage: unknown. During the same period patient was treated with MERCAPTOPURINE, CYTARABINE, HYDROCORTISONE. Patient died.
Methotrexate Side Effects Report #5157325-4
Methotrexate side effect was reported by a Physician from GERMANY on Oct 06, 2006. Male patient, 61 years of age, weighting 134.5 lb, was diagnosed with acute lymphocytic leukaemia and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: anal haemorrhage, ascites, blood pressure decreased, convulsion, diarrhoea haemorrhagic, enterocolitis haemorrhagic, gastrointestinal haemorrhage, haematemesis. Methotrexate dosage: unknown. During the same period patient was treated with ONCASPAR, PURINETHOL, LEUCOVORIN CALCIUM, LITAREX. Patient was hospitalized. Patient died on 10/26/2006.
Methotrexate Side Effects Report #5254408-5
Methotrexate side effect was reported by a Consumer or non-health professional from on Feb 22, 2007. Female patient, 56 years of age, was diagnosed with acute lymphocytic leukaemia, bone marrow conditioning regimen and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, c-reactive protein increased, coma, convulsion, extensor plantar response, eyelid ptosis, graft versus host disease, hypertension, leukoencephalopathy. Methotrexate dosage: unknown. During the same period patient was treated with MERCAPTOPURINE, CYCLOPHOSPHAMIDE, VINCRISTINE, DAUNORUBICIN, ASPARAGINASE, CYTARABINE, FLUDARABINE. Patient died.
Methotrexate Side Effects Report #4670296-X
Methotrexate side effect was reported by a Consumer or non-health professional from on Nov 09, 2004. Female patient, child 5 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: accidental overdose, back pain
, cardiopulmonary failure, coma, convulsion, tachycardia. Methotrexate dosage: 600 MG ONCE IT. Patient was hospitalized. Patient recovered.Methotrexate Side Effects Report #5414751-3
Methotrexate side effect was reported by a Physician from UNITED STATES on July 31, 2007. Female patient, child 4 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: brain oedema, convulsion, gaze palsy, hypertension, reversible posterior leukoencephalopathy syndrome, unresponsive to stimuli. Methotrexate dosage: unknown. During the same period patient was treated with VINCRISTINE, PREDNISONE, DAUNORUBICIN. Patient recovered.
Methotrexate Side Effects Report #5676944-X
Methotrexate side effect was reported by a Health Professional from SWITZERLAND on Mar 20, 2008. Male patient, child 4 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: adenoviral hepatitis, coagulopathy, convulsion, febrile neutropenia, multi-organ failure. Methotrexate dosage: unknown. During the same period patient was treated with VINCRISTINE SULPHATE, MERCAPTOPURINE, DEXAMETHASONE. Patient died.
Methotrexate Side Effects Report #5676976-1
Methotrexate side effect was reported by a Health Professional from SWITZERLAND on Mar 17, 2008. Male patient, child 4 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: adenoviral hepatitis, coagulopathy, convulsion, febrile neutropenia, multi-organ failure. Methotrexate dosage: unknown. During the same period patient was treated with VINCRISTINE SULPHATE, MERCAPTOPURINE, DEXAMETHASONE. Patient died.
Methotrexate Side Effects Report #5678209-9
Methotrexate side effect was reported by a Physician from SWITZERLAND on Mar 07, 2008. Male patient, child 3. years of age, was diagnosed with acute lymphocytic leukaemia and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: adenoviral hepatitis, brain hypoxia, coagulation test abnormal, coagulopathy, convulsion, febrile neutropenia, gastrointestinal haemorrhage, grand mal convulsion. Methotrexate dosage: 20 MG/M2, QW, ORAL. During the same period patient was treated with VINCRISTINE, DEXAMETHASONE, MERCAPTOPURINE. Patient died.
Methotrexate Side Effects Report #5852311-0
Methotrexate side effect was reported by a Physician from UNITED STATES on Aug 07, 2008. Male patient, child 3 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: adenoviral hepatitis, brain hypoxia, coagulopathy, convulsion, cough, epistaxis, febrile neutropenia, gastrointestinal haemorrhage, haemorrhage intracranial. Methotrexate dosage: 20 MG/M2 (ORAL( AND IV INTHRATHECAL MTX X1. Patient was hospitalized. Patient died.
Methotrexate Side Effects Report #4658299-2
Methotrexate side effect was reported by a Physician from on Apr 21, 2005. Male patient, child 3 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: convulsion, electroencephalogram abnormal, nuclear magnetic resonance imaging abnormal. Methotrexate dosage: unknown. During the same period patient was treated with MERCAPTOPURINE, CYTARABINE, HYDROCORTISONE. Patient recovered.
Methotrexate Side Effects Report #5368412-X
Methotrexate side effect was reported by a Health Professional from JAPAN on June 08, 2007. Male patient, 25 years of age, weighting 150.6 lb, was diagnosed with acute lymphocytic leukaemia and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: blood bilirubin increased, brain oedema, cerebral haemorrhage, convulsion, hemiplegia, loss of consciousness, superior sagittal sinus thrombosis. Methotrexate dosage: 15 MG, 8 DOSES, INTRATHECAL. During the same period patient was treated with PREDNISOLONE, CYTARABINE, ADRIAMYCIN PFS, VINCRISTINE, CYCLOPHOSPHAMIDE, MITOXANTRONE. Patient was hospitalized. Patient recovered.
Methotrexate Side Effects Report #5531352-7
Methotrexate side effect was reported by a Consumer or non-health professional from GERMANY on Nov 14, 2007. Female patient, 15 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: convulsion, glioma. Methotrexate dosage: unknown. During the same period patient was treated with DOXORUBICIN, CORTISONE, VINCRISTINE, DAUNORUBICIN, ASPARAGINANE, CYCLOPHOSPHAMIDE, MERCAPTOPURINE, CYTARABINE. Patient died.
Methotrexate Side Effects Report #5531351-5
Methotrexate side effect was reported by a Consumer or non-health professional from GERMANY on Nov 14, 2007. Female patient, 13 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: convulsion, glioma. Methotrexate dosage: unknown. During the same period patient was treated with DOXORUBICIN, CORTISONE, VINCRISTINE, DAUNORUBICIN, ASPARAGINASE, CYCLOPHOSPHAMIDE, MERCAPTOPURINE, CYTARABINE. Patient died.
Methotrexate Side Effects Report #4755972-2
Methotrexate side effect was reported by a Health Professional from SWITZERLAND on Aug 18, 2005. Male patient, 13 years of age, weighting 112.4 lb, was diagnosed with acute lymphocytic leukaemia and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: convulsion, encephalopathy, renal failure acute, respiratory arrest. Methotrexate dosage: unknown. During the same period patient was treated with LASIX, OMEPRAZOLE, LORAZEPAM, HYDROCORTISONE, LEUCOVORIN. Patient recovered.
Methotrexate Side Effects Report #4763234-2
Methotrexate side effect was reported by a Consumer or non-health professional from ALBANIA on Aug 19, 2005. Male patient, 13 years of age, was diagnosed with acute lymphocytic leukaemia, convulsion and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: convulsion, dialysis
, encephalopathy, neurotoxicity, renal failure acute, respiratory arrest. Methotrexate dosage: 500 MG/M2 IV. During the same period patient was treated with LORAZEPAM, LAXIS, OMEPRAZOLE, HYDROCORTISONE, CYTARABINE, LEUCOVORIN. Patient was hospitalized. Patient recovered.Methotrexate Side Effects Report #5533828-5
Methotrexate side effect was reported by a Consumer or non-health professional from GERMANY on Nov 14, 2007. Male patient, child 12 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: convulsion, glioma, intracranial pressure increased, nervous system disorder. Methotrexate dosage: unknown. During the same period patient was treated with DOXORUBICIN, CORTISONE, VINCRISTINE, DAUNORUBICIN, ASPARAGINASE, CYCLOPHOSPHAMIDE, CYTARABINE. Patient died.
Methotrexate Side Effects Report #5533828-5
Methotrexate side effect was reported by a Physician from GERMANY on Nov 14, 2007. Male patient, child 12 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: convulsion, glioma, intracranial pressure increased, nervous system disorder. Methotrexate dosage: unknown. During the same period patient was treated with DOXORUBICIN, CORTISONE, VINCRISTINE, DAUNORUBICIN, ASPARAGINASE, CYCLOPHOSPHAMIDE, MERCAPTOPURINE, CYTARABINE. Patient died.
Methotrexate Side Effects Report #6027141-X
Methotrexate side effect was reported by a Pharmacist from UNITED STATES on Dec 31, 2008. Male patient, weighting 116.4 lb, was diagnosed with acute lymphocytic leukaemia and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: aphasia
, arachnoiditis, cerebral infarction, convulsion, encephalopathy, facial paresis, hemiparesis, hypoaesthesia, nausea . Methotrexate dosage: 15MG X 8 IT. Patient was hospitalized. Patient recovered.Methotrexate Side Effects Report #4563043-3
Methotrexate side effect was reported by a Consumer or non-health professional from on May 28, 2004. Female patient was diagnosed with acute lymphocytic leukaemia and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: convulsion. Methotrexate dosage: unknown. During the same period patient was treated with CYTARABINE, MERCAPTOPURINE, LEUCOVORIN. Patient recovered.
Methotrexate Side Effects Report #4568435-4
Methotrexate side effect was reported by a Consumer or non-health professional from on May 28, 2004. Female patient was diagnosed with acute lymphocytic leukaemia and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: convulsion. Methotrexate dosage: unknown. During the same period patient was treated with CYTARABINE, MERCAPTOPURINE, LEUCOVORIN CALCIUM. Patient recovered.
Methotrexate Side Effects Report #4622273-2
Methotrexate side effect was reported by a Health Professional from on Mar 24, 2005. Female patient, weighting 16.97 lb, was diagnosed with acute lymphocytic leukaemia, prophylaxis and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: convulsion, simple partial seizures, tremor. Methotrexate dosage: 7.5 MG INTRATHECAL. During the same period patient was treated with CYTARABINE, CEFEPIME, LEUCOVORIN CALCIUM. Patient recovered.
Methotrexate Side Effects Report #4714821-9
Methotrexate side effect was reported by a Consumer or non-health professional from UNITED STATES on July 14, 2005. Female patient, weighting 50.04 lb, was diagnosed with acute lymphocytic leukaemia and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: abnormal behaviour, asthenia, convulsion, depressed level of consciousness, electroencephalogram abnormal, encephalopathy, full blood count abnormal, hypotonia, loss of consciousness. Methotrexate dosage: 12 MG GIVEN ON 6/23/2005 (DAY 8). During the same period patient was treated with VINCRISTINE, DEXAMETHASONE, PEG ASPARAGINASE, CYTARABINE. Patient recovered.
Methotrexate Side Effects Report #4937280-X
Methotrexate side effect was reported by a Consumer or non-health professional from UNITED STATES on Mar 07, 2006. Male patient, weighting 18.52 lb, was diagnosed with acute lymphocytic leukaemia and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: blood electrolytes abnormal, blood glucose abnormal, convulsion, dehydration, polyuria, subarachnoid haemorrhage, subdural haemorrhage. Methotrexate dosage: 1520 MG. Patient was hospitalized. Patient recovered.
Methotrexate Side Effects Report #4703966-5
Methotrexate side effect was reported by a Consumer or non-health professional from on June 15, 2005. Male patient, 14 years of age, was treated with Methotrexate. After drug was administered, patient experienced the following side effects: convulsion, csf test abnormal, febrile neutropenia, intestinal dilatation, leukopenia, lymphopenia, neoplasm malignant, obstruction. Methotrexate dosage: unknown. During the same period patient was treated with VINCRISTINE, DOXORUBICIN, METHYLPREDNISOLONE, CYCLOPHOSPHAMIDE, RITUXIMAB, CYTARABINE, HYDROCORTISONE. Patient recovered.
Methotrexate Side Effects Report #4733142-1
Methotrexate side effect was reported by a Consumer or non-health professional from THAILAND on June 15, 2005. Male patient, 14 years of age, was treated with Methotrexate. After drug was administered, patient experienced the following side effects: abdominal mass, convulsion, csf test abnormal, febrile neutropenia, intestinal obstruction, leukopenia, lymphopenia, small intestinal obstruction. Methotrexate dosage: 5 MG OTH/500 MG/M2 OTH IV/IT. During the same period patient was treated with VINCRISTINE, DOXORUBICIN, METHYLPREDNISOLONE, CYCLOPHOSPHAMIDE, RITUXIMAB, CYTOSINE ARABINOSIDE, HYDROCORTISONE. Patient recovered.
Methotrexate Side Effects Report #4707255-4
Methotrexate side effect was reported by a Consumer or non-health professional from KUWAIT on June 17, 2005. Male patient, child 10 years of age, was treated with Methotrexate. After drug was administered, patient experienced the following side effects: convulsion, depressed level of consciousness, diplopia, disorientation, eye movement disorder. Methotrexate dosage: unknown. During the same period patient was treated with CISPLATIN, ADRIAMYCIN PFS, LEUCOVORIN CALCIUM. Patient recovered.
Methotrexate Side Effects Report #5580490-1
Methotrexate side effect was reported by a Consumer or non-health professional from UNITED STATES on Dec 31, 2007. Female patient, weighting 117.9 lb, was treated with Methotrexate. After drug was administered, patient experienced the following side effects: convulsion, dyskinesia, headache
, loss of consciousness, mouth haemorrhage, status epilepticus. Methotrexate dosage: 75 MG. During the same period patient was treated with PREDNISONE, VINCRISTINE SULPHATE, CYCLOPHOSPHAMIDE, CYTARABINE, DAUNORUBICIN, MERCAPTOPURINE. Patient was hospitalized. Patient recovered.Methotrexate Side Effects Report #4707367-5
Methotrexate side effect was reported by a Consumer or non-health professional from UNITED STATES on July 01, 2005. Male patient, weighting 22.93 lb, was treated with Methotrexate. After drug was administered, patient experienced the following side effects: catheter related infection, convulsion, diarrhoea, hyponatraemia, hypotension, pyrexia. Methotrexate dosage: 7.5 MG IT DAY 1, EVERY WEEK FOR 2 WEEKS. During the same period patient was treated with HYDROCORTISONE, CYTARABINE, LEUCOVORIN CALCIUM, CYCLOPHOSPHAMIDE. Patient was hospitalized. Patient recovered.