Methotrexate and renal failure Patient Reports February 09, 2010

Methotrexate Side Effects Report #5757385-3
Methotrexate side effect was reported by a Health Professional from UNITED KINGDOM on May 23, 2008. Female patient, 70 years of age, was diagnosed with systemic lupus erythematosus and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: bundle branch block right, corneal deposits, lipid metabolism disorder, nephropathy, renal failure. Methotrexate dosage: 15 MG. During the same period patient was treated with PREDNISOLONE, HYDROXYCHLOROQUINE SULPHATE. Patient recovered.

Methotrexate Side Effects Report #5324643-6
Methotrexate side effect was reported by a Consumer or non-health professional from NORWAY on Apr 20, 2007. Female patient, 80 years of age, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: endocarditis , pancytopenia, renal failure. Methotrexate dosage: 10 MG, 1 IN 1 WK, ORAL. During the same period patient was treated with ERYTHROMYCIN. Patient died.

Methotrexate Side Effects Report #6138953-6
Methotrexate side effect was reported by a Physician from UNITED STATES on Mar 18, 2009. Female patient, 78 years of age, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: central nervous system lymphoma, cerebral toxoplasmosis, epstein-barr virus infection, lymphoproliferative disorder, multi-organ failure, renal failure. Methotrexate dosage: unknown. Patient recovered.

Methotrexate Side Effects Report #5530238-1
Methotrexate side effect was reported by a Health Professional from FRANCE on Nov 26, 2007. Female patient, 74 years of age, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: haemorrhage intracranial, pancytopenia, renal failure, septic shock. Methotrexate dosage: unknown. During the same period patient was treated with GRANULOCYTE CSF. Patient died.


Methotrexate Side Effects Report #5585875-5
Methotrexate side effect was reported by a Consumer or non-health professional from on Jan 02, 2008. Female patient, 74 years of age, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: cerebral haemorrhage, pancytopenia, renal failure, septic shock. Methotrexate dosage: unknown. During the same period patient was treated with NSAIDS, STEROIDS. Patient died.

Methotrexate Side Effects Report #4557840-8
Methotrexate side effect was reported by a Health Professional from on Jan 04, 2005. Female patient, 73 years of age, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: diarrhoea, haemodialysis, multi-organ failure, platelet count decreased, pneumonia , pyelonephritis, renal failure, respiratory failure, septic shock. Methotrexate dosage: 12.5 MG WEEKLY. During the same period patient was treated with SIMVASTATIN, FOLIC ACID, AMLODIPINE. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #5099452-6
Methotrexate side effect was reported by a Health Professional from UNITED KINGDOM on Aug 28, 2006. Female patient, 61 years of age, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: arrhythmia , interstitial lung disease, metabolic acidosis, renal failure. Methotrexate dosage: unknown. During the same period patient was treated with ENBREL. Patient was hospitalized. Patient died.

Methotrexate Side Effects Report #5106904-9
Methotrexate side effect was reported by a Consumer or non-health professional from on Aug 30, 2006. Female patient, 61 years of age, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: arrhythmia , metabolic acidosis, pneumonitis, pulmonary fibrosis , renal failure. Methotrexate dosage: (25 MG). During the same period patient was treated with ENBREL. Patient was hospitalized. Patient died.

Methotrexate Side Effects Report #5122756-5
Methotrexate side effect was reported by a Health Professional from UNITED KINGDOM on Sept 25, 2006. Female patient, 61 years of age, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: arrhythmia , bacterial infection , interstitial lung disease, metabolic acidosis, pneumocystis jiroveci infection, renal failure, tuberculosis . Methotrexate dosage: 25 MG 2/WK. During the same period patient was treated with ENBREL. Patient died.


Methotrexate Side Effects Report #4993495-6
Methotrexate side effect was reported by a Pharmacist from UNITED STATES on May 04, 2006. Male patient, 59 years of age, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, erythema multiforme, pain in extremity, pancytopenia, renal failure, retroperitoneal haemorrhage, sepsis . Methotrexate dosage: 2.5MG TABLETS AS 2 TABLETS PO. During the same period patient was treated with ACETAMINOPHEN, ASPIRIN, CHLORPHENIRAMINE MALEATE, CITALOPRAM HYDROBROMIDE, FOLIC ACID, FUROSEMIDE, IBUPROFEN, LORAZEPAM. Patient died.

Methotrexate Side Effects Report #4827642-3
Methotrexate side effect was reported by a Health Professional from UNITED KINGDOM on Oct 28, 2005. Male patient, 55 years of age, weighting 130.1 lb, was diagnosed with rheumatoid arthritis , amyloidosis and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: amyloidosis, blister, diarrhoea, haemodialysis, necrotising fasciitis, renal failure, streptococcal sepsis, venous thrombosis, vomiting. Methotrexate dosage: 15 MG WEEKLY PO. During the same period patient was treated with FOLIC ACID, KINERET, HYDROCORTISONE, CELEBREX, ATORVASTATIN CALCIUM, PERINDOPRIL, WARFARIN. Patient was hospitalized. Patient died on 08/23/2005.

Methotrexate Side Effects Report #6128875-9
Methotrexate side effect was reported by a Consumer or non-health professional from UNITED STATES on Mar 05, 2009. Male patient, 51 years of age, weighting 150.0 lb, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: blister, hypotension, immunosuppression, leukopenia, platelet count decreased, pyrexia, renal failure, therapeutic agent toxicity. Methotrexate dosage: 7.5 MG;WEEKLY;ORAL. During the same period patient was treated with COREG, SYNTHROID. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #5598664-2
Methotrexate side effect was reported by a Physician from GERMANY on Jan 08, 2008. Male patient, 16 years of age, was diagnosed with prophylaxis against graft versus host disease, stem cell transplant and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: pancreatitis acute, renal failure. Methotrexate dosage: unknown. During the same period patient was treated with ETOPOSIDE, CYCLOSPORINE, STEROIDS. Patient recovered.

Methotrexate Side Effects Report #5598651-4
Methotrexate side effect was reported by a Physician from GERMANY on Jan 08, 2008. Male patient, child 12 years of age, was diagnosed with prophylaxis against graft versus host disease, stem cell transplant and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, capillary leak syndrome, dermatitis exfoliative, mucosal inflammation, multi-organ failure, renal failure. Methotrexate dosage: 2.5 MG/M2. During the same period patient was treated with FLUDARABINE PHOSPHATE, TREOSULPHAN, MELPHALAN, CYCLOSPORINE. Patient died.


Methotrexate Side Effects Report #5598690-3
Methotrexate side effect was reported by a Physician from GERMANY on Jan 08, 2008. Female patient, child 10 years of age, was diagnosed with prophylaxis against graft versus host disease, bone marrow conditioning regimen and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: acute graft versus host disease in skin, epstein-barr virus infection, leukaemia recurrent, mucosal inflammation, pericardial effusion, pulmonary oedema, renal failure. Methotrexate dosage: unknown. During the same period patient was treated with ETOPOSIDE, CYCLOSPORINE. Patient recovered.

Methotrexate Side Effects Report #5306752-0
Methotrexate side effect was reported by a Physician from NETHERLANDS on Apr 03, 2007. Female patient, 61 years of age, was diagnosed with non-hodgkin's lymphoma recurrent and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: creatinine renal clearance decreased, leukopenia, mucosal inflammation, pyrexia, renal failure, renal impairment, thrombocytopenia. Methotrexate dosage: 30 MG/M2 OTH PU. During the same period patient was treated with ETOPOSIDE, CISPLATIN, IFOSFAMIDE, PANTOPRAZOL, CYTARABINE, DEXAMETHASONE. Patient recovered.

Methotrexate Side Effects Report #4619408-4
Methotrexate side effect was reported by a Physician from on May 09, 2002. Male patient, 82 years of age, weighting 163.0 lb, was diagnosed with non-hodgkin's lymphoma and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: mucosal inflammation, pancytopenia, rash follicular, renal failure. Methotrexate dosage: 500 MG/M2 IV. During the same period patient was treated with CYTOXAN, ADRIAMYCIN PFS, VINCRISTINE, BLEOMYCIN. Patient was hospitalized. Patient died on 05/17/2002.

Methotrexate Side Effects Report #4957669-2
Methotrexate side effect was reported by a Health Professional from UNITED STATES on Mar 15, 2006. Male patient, 61 years of age, was diagnosed with non-hodgkin's lymphoma and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: mucosal inflammation, neurotoxicity, renal failure. Methotrexate dosage: 1990 MG ONCE IV. During the same period patient was treated with CIPRO, FLUCONAZOLE, ATIVAN, ALLOPURINOL, ACYCLOVIR, BACTRIM, VALSARTAN, HYDROCHLOROTHIAZIDE. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #5201706-7
Methotrexate side effect was reported by a Health Professional from UNITED STATES on Jan 25, 2006. Male patient, 46 years of age, was diagnosed with non-hodgkin's lymphoma and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: renal failure. Methotrexate dosage: unknown. During the same period patient was treated with CIPRO, ACYCLOVIR, FLUCONAZOLE, ATIVAN, DECADRON. Patient was hospitalized. Patient recovered.


Methotrexate Side Effects Report #5462469-3
Methotrexate side effect was reported by a Health Professional from UNITED STATES on May 25, 2007. Male patient, child 10 years of age, weighting 88.18 lb, was diagnosed with neuroblastoma  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: renal failure. Methotrexate dosage: 850 MG. During the same period patient was treated with ESOMEPRAZOLE. Patient recovered.

Methotrexate Side Effects Report #5364637-8
Methotrexate side effect was reported by a Health Professional from UNITED STATES on May 10, 2007. Male patient, 20 years of age, weighting 249.1 lb, was diagnosed with neoplasm malignant and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: renal failure. Methotrexate dosage: 4.5MG/M2. During the same period patient was treated with RESPIRIDINE, AMLODIPINE, ONDANSETRON, PREDNISONE, INSULIN ASPART, ADDERALL. Patient recovered.

Methotrexate Side Effects Report #5462465-6
Methotrexate side effect was reported by a Health Professional from UNITED STATES on May 25, 2007. Male patient, child 10 years of age, weighting 88.18 lb, was diagnosed with neoplasm malignant and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: renal failure. Methotrexate dosage: 4.5 MG/M2 (435 MG). During the same period patient was treated with ASPARAGENASE, CEFEPIME, MERCUPTOPURENE, FAMOTIDINE. Patient recovered.

Methotrexate Side Effects Report #5102305-8
Methotrexate side effect was reported by a Health Professional from NETHERLANDS on Sept 05, 2006. Male patient, 29 years of age, was diagnosed with neoplasm and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: dialysis , neutropenia, pericardial haemorrhage, renal failure, staphylococcal bacteraemia, thrombocytopenia. Methotrexate dosage: unknown. Patient died.

Methotrexate Side Effects Report #4892414-0
Methotrexate side effect was reported by a Health Professional from UNITED STATES on Jan 25, 2006. Male patient, 61 years of age, was diagnosed with mantle cell lymphoma, non-hodgkin's lymphoma and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: mucosal inflammation, nervous system disorder, renal failure. Methotrexate dosage: 1990 MG IV. During the same period patient was treated with ALLOPURINOL, CIPRO, FLUCONAZOLE, ACYCLOVIR, BACTRIM, VALSARTAN, ATIVAN. Patient was hospitalized. Patient recovered.


Methotrexate Side Effects Report #4909141-3
Methotrexate side effect was reported by a Health Professional from UNITED STATES on Jan 25, 2006. Male patient, 61 years of age, was diagnosed with mantle cell lymphoma and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: mucosal inflammation, neurotoxicity, renal failure. Methotrexate dosage: 1990 MG ONCE IV. During the same period patient was treated with CYTARABINE, CIPRO, FLUCONAZOLE, ATIVAN, ALLOPURINOL, ACYCLOVIR, BACTRIM, VALSARTAN. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #5691510-8
Methotrexate side effect was reported by a Pharmacist from UNITED STATES on Mar 21, 2008. Female patient, 49 years of age, weighting 381.4 lb, was diagnosed with lymphoma  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: hyperuricaemia, renal failure. Methotrexate dosage: 1820 MG ONCE IV. During the same period patient was treated with CYTARABINE, RITUXIMAB, LEUCOVORIN CALCIUM. Patient died on 03/13/2008.

Methotrexate Side Effects Report #5952546-2
Methotrexate side effect was reported by a Pharmacist from UNITED STATES on Jan 16, 2008. Male patient was diagnosed with lymphoma , sarcoma and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: renal failure. Methotrexate dosage: unknown. Patient recovered.

Methotrexate Side Effects Report #5493113-7
Methotrexate side effect was reported by a Health Professional from FRANCE on Oct 05, 2007. Female patient, child 12 years of age, was diagnosed with diffuse large b-cell lymphoma and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, neutropenia, overdose, renal failure, transaminases increased. Methotrexate dosage: 4260 MG; INTRAVENOUS. During the same period patient was treated with ENDOXAN ASTA, CARBOXYPEPTIDASE G, ELVORINE, BACTRIM, ZOFRAN, DEXAMETHASONE. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #5015470-8
Methotrexate side effect was reported by a Pharmacist from UNITED STATES on May 30, 2006. Male patient, 70 years of age, weighting 185.0 lb, was diagnosed with demyelinating polyneuropathy and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: dialysis , mucosal inflammation, pain of skin, pancytopenia, rash erythematous, renal failure, sepsis , treatment noncompliance. Methotrexate dosage: 7.5 MG - M-W-F (OUTPATIENT). Patient was hospitalized. Patient recovered.


Methotrexate Side Effects Report #5145866-5
Methotrexate side effect was reported by a Consumer or non-health professional from UNITED STATES on Oct 20, 2006. Male patient, 58 years of age, was diagnosed with central nervous system lymphoma and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: blood glucose increased, renal failure, renal tubular necrosis. Methotrexate dosage: unknown. During the same period patient was treated with LEUCOVORIN CALCIUM, PANTOPRAZOLE, SCOPOLAMINE, DEXAMETHASONE. Patient recovered.

Methotrexate Side Effects Report #4617019-8
Methotrexate side effect was reported by a Physician from on Mar 03, 2005. Female patient, child 10 years of age, was diagnosed with burkitt's lymphoma and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: cardiac failure, coma, renal failure, respiratory distress. Methotrexate dosage: unknown. During the same period patient was treated with VINCRISTINE, CYCLOPHOSPHAMIDE, PREDNISONE, HYDROCORTISONE. Patient died.

Methotrexate Side Effects Report #4629384-6
Methotrexate side effect was reported by a Consumer or non-health professional from on Mar 03, 2005. Female patient, child 10 years of age, was diagnosed with burkitt's lymphoma and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: cardiac failure, coma, renal failure, respiratory distress, respiratory failure. Methotrexate dosage: 15 MG PER_CYCLE. During the same period patient was treated with VINCRISTINE, CYCLOPHOSPHAMIDE, PREDNISOLONE, HYDROCORTISONE. Patient was hospitalized. Patient died.

Methotrexate Side Effects Report #5368535-5
Methotrexate side effect was reported by a Health Professional from FRANCE on June 04, 2007. Female patient, 16 years of age, was diagnosed with bone sarcoma and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: blood pressure increased, convulsion, cytolytic hepatitis, mucosal inflammation, renal failure, renal tubular disorder, thrombocytopenia. Methotrexate dosage: unknown. During the same period patient was treated with DANTROLENE, ONDANESTRON, METHYLPREDNISOLONE, NALBUPHINE. Patient recovered.

Methotrexate Side Effects Report #5133205-5
Methotrexate side effect was reported by a Physician from FRANCE on Oct 06, 2006. Female patient, 16 years of age, was diagnosed with bone sarcoma, analgesic effect and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: blood pressure increased, convulsion, cytolytic hepatitis, mucosal inflammation, renal failure, renal tubular disorder, thrombocytopenia. Methotrexate dosage: unknown. During the same period patient was treated with ETOPOSIDE, IFOSFAMIDE, ONDANSETRON, DANTROLENE. Patient recovered.


Methotrexate Side Effects Report #5157977-9
Methotrexate side effect was reported by a Consumer or non-health professional from on Nov 15, 2006. Female patient, 16 years of age, was diagnosed with bone sarcoma, analgesic effect, prophylaxis of nausea and vomiting and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: blood pressure increased, convulsion, cytolytic hepatitis, mucosal inflammation, renal failure, renal tubular disorder, thrombocytopenia. Methotrexate dosage: unknown. During the same period patient was treated with DANTROLENE, ETOPOSIDE, IFOSFAMIDE, ONDANSETRON, METHYLPREDNISOLONE, NALBUPHINE. Patient recovered.

Methotrexate Side Effects Report #4892416-4
Methotrexate side effect was reported by a Consumer or non-health professional from UNITED STATES on Jan 25, 2006. Male patient, 46 years of age, was diagnosed with adult t-cell lymphoma/leukaemia, non-hodgkin's lymphoma and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: renal failure. Methotrexate dosage: unknown. During the same period patient was treated with CIPRO, ACYCLOVIR, FLUCONAZOLE, ATIVAN, DECADRON. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #5469268-7
Methotrexate side effect was reported by a Pharmacist from UNITED STATES on Sept 26, 2007. Male patient, weighting 69.89 lb, was diagnosed with acute lymphocytic leukaemia and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: hypertension, renal failure. Methotrexate dosage: 545 MG + 4860 MG X1 IV DRIP. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #4701529-9
Methotrexate side effect was reported by a Consumer or non-health professional from on June 14, 2005. Female patient was diagnosed with acute lymphocytic leukaemia and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: creatinine renal clearance decreased, neurotoxicity, renal failure. Methotrexate dosage: unknown. Patient recovered.

Methotrexate Side Effects Report #4705201-0
Methotrexate side effect was reported by a Consumer or non-health professional from on June 14, 2005. Male patient was diagnosed with acute lymphocytic leukaemia and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: neurotoxicity, renal failure. Methotrexate dosage: unknown. Patient recovered.


Methotrexate Side Effects Report #4720208-5
Methotrexate side effect was reported by a Consumer or non-health professional from FRANCE on June 15, 2005. Female patient was diagnosed with acute lymphocytic leukaemia and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: neurotoxicity, renal failure. Methotrexate dosage: unknown. Patient recovered.

Methotrexate Side Effects Report #4790962-5
Methotrexate side effect was reported by a Consumer or non-health professional from UNITED STATES on Sept 22, 2005. Female patient, 76 years of age, was treated with Methotrexate. After drug was administered, patient experienced the following side effects: dialysis , haemolysis, hypersensitivity, renal failure. Methotrexate dosage: unknown. During the same period patient was treated with ANTIHYPERTENSIVES. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #4622111-8
Methotrexate side effect was reported by a Consumer or non-health professional from on Nov 25, 2003. Female patient, 66 years of age, was treated with Methotrexate. After drug was administered, patient experienced the following side effects: blood pressure increased, renal failure, renal vessel disorder. Methotrexate dosage: 22.5 MG WEEKLY. During the same period patient was treated with ACIPHEX, AZATHIOPRINE, DICLOFENAC, FOLIC ACID, TRIAMTERENE AND HYDROCHLOROTHIAZIDE, HYDROXYCHLOROQUINE PHOSPHATE, ISRADIPINE, METOPROLOL SUCCINATE. Patient recovered.

Methotrexate Side Effects Report #4622956-4
Methotrexate side effect was reported by a Consumer or non-health professional from on Apr 01, 2004. Female patient, 64 years of age, was treated with Methotrexate. After drug was administered, patient experienced the following side effects: hepatic failure, interstitial lung disease, mouth ulceration, renal failure, thrombocytopenic purpura. Methotrexate dosage: unknown. During the same period patient was treated with ETANERCEPT. Patient died.

Methotrexate Side Effects Report #5710835-0
Methotrexate side effect was reported by a Pharmacist from UNITED STATES on Apr 17, 2008. Female patient, 57 years of age, was treated with Methotrexate. After drug was administered, patient experienced the following side effects: dermatitis exfoliative, renal failure. Methotrexate dosage: unknown. Patient recovered.

Methotrexate Side Effects Report #5519574-2
Methotrexate side effect was reported by a Health Professional from UNITED KINGDOM on Nov 12, 2007. Male patient, 14 years of age, was treated with Methotrexate. After drug was administered, patient experienced the following side effects: herpes zoster, renal failure. Methotrexate dosage: unknown. During the same period patient was treated with DICLOFENAC, PREDNISOLONE. Patient recovered.

Methotrexate Side Effects Report #6105006-2
Methotrexate side effect was reported by a Consumer or non-health professional from UNITED STATES on Mar 04, 2009. Male patient, weighting 260.0 lb, was treated with Methotrexate. After drug was administered, patient experienced the following side effects: haemodialysis, hepatic enzyme increased, mucosal inflammation, myocardial infarction, pancytopenia, renal failure. Methotrexate dosage: unknown. During the same period patient was treated with RITUXIMAB. Patient was hospitalized. Patient recovered.