Myozyme and cyanosis Patient Reports February 09, 2010

Myozyme Side Effects Report #5677967-7
Myozyme side effect was reported by a Health Professional from UNITED STATES on Mar 05, 2008. Female patient, child 9 years of age, weighting 66.14 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: anxiety , chest discomfort, cyanosis, dyspnoea, eye swelling, flushing, hypersensitivity, nausea , pallor. Myozyme dosage: 20 MG/KG, Q2W, INTRAVENOUS. During the same period patient was treated with FLONASE, CONCERTA, ALBUTEROL. Patient was hospitalized. Patient recovered.

Myozyme Side Effects Report #5799564-5
Myozyme side effect was reported by a Health Professional from UNITED STATES on June 20, 2008. Female patient, child 9 years of age, weighting 66.14 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: anxiety , aphasia , blood pressure increased, chest discomfort, cyanosis, dyspnoea, eye swelling, flushing, hypersensitivity. Myozyme dosage: 20 MG/KG, Q2W, INTRAVENOUS. During the same period patient was treated with FLONASE, CONCERTA, ALBUTEROL. Patient was hospitalized. Patient recovered.

Myozyme Side Effects Report #5832451-2
Myozyme side effect was reported by a Physician from UNITED STATES on July 21, 2008. Female patient, child 9 years of age, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: arthralgia, chest discomfort, cough, cyanosis, dysgeusia, dyspnoea, face oedema, flushing, headache . Myozyme dosage: 20 MG/KG, Q2W, INTRAVENOUS. During the same period patient was treated with PREDNISONE, BENADRYL. Patient recovered.

Myozyme Side Effects Report #6055334-4
Myozyme side effect was reported by a Physician from UNITED STATES on Jan 02, 2009. Female patient, child 9 years of age, weighting 66.14 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: anxiety , blood pressure increased, chest discomfort, circumoral oedema, cyanosis, dyspnoea, eye swelling, flushing, hypersensitivity. Myozyme dosage: 20 MG/KG, Q2W; INTRAVENOUS. During the same period patient was treated with FLONASE, CONCERTA, ALBUTEROL. Patient was hospitalized. Patient recovered.


Myozyme Side Effects Report #5940267-1
Myozyme side effect was reported by a Physician from FRANCE on Oct 21, 2008. Female patient, 73 years of age, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, bradycardia, bronchitis , cough, cyanosis, dysphagia, electrocardiogram abnormal, hypotension, tachypnoea. Myozyme dosage: unknown. During the same period patient was treated with TAMSULOSIN. Patient was hospitalized. Patient recovered.

Myozyme Side Effects Report #6122250-9
Myozyme side effect was reported by a Physician from ISRAEL on Mar 02, 2009. Female patient, child 7 years of age, weighting 38.58 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: arrhythmia , cyanosis, pulse absent. Myozyme dosage: 20 MG/KG, INTRAVENOUS. Patient died on 02/19/2009.

Myozyme Side Effects Report #5319721-1
Myozyme side effect was reported by a Physician from GERMANY on Apr 18, 2007. Male patient, 59 years of age, weighting 158.7 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: cyanosis, hypersensitivity, infusion related reaction. Myozyme dosage: 20 MG/KG Q2WKS IV. During the same period patient was treated with ATACAND, CARMEN. Patient recovered.

Myozyme Side Effects Report #5196519-9
Myozyme side effect was reported by a Physician from PORTUGAL on Dec 07, 2006. Female patient, child 5 years of age, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: aspiration, cardio-respiratory arrest, cyanosis, dyspnoea, nasopharyngitis. Myozyme dosage: unknown. Patient died on 12/07/2006.

Myozyme Side Effects Report #5538424-1
Myozyme side effect was reported by a Physician from PORTUGAL on Nov 21, 2007. Female patient, child 5 years of age, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: cardio-respiratory arrest, cyanosis, dyspnoea, mydriasis, nasopharyngitis. Myozyme dosage: 20 MG Q2WKS IV. During the same period patient was treated with AMOXICILLIN. Patient died on 12/07/2006.


Myozyme Side Effects Report #5326886-4
Myozyme side effect was reported by a Physician from TAIWAN, PROVINCE OF CHINA on Apr 28, 2007. Female patient, child 4 years of age, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: cardiac arrest , cyanosis, device malfunction, respiratory failure. Myozyme dosage: 20 MG/KG Q2WKS IV. During the same period patient was treated with ALPHA. Patient died on 04/28/2007.

Myozyme Side Effects Report #5372686-9
Myozyme side effect was reported by a Physician from AUSTRALIA on June 12, 2007. Female patient, child 3 years of age, weighting 34.39 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: blood pressure systolic decreased, cyanosis, gait disturbance, hypersensitivity, hypotonia. Myozyme dosage: 20 MG/KG QW2KS IV. During the same period patient was treated with ALPHA. Patient recovered.

Myozyme Side Effects Report #6081258-2
Myozyme side effect was reported by a Physician from UNITED STATES on Feb 02, 2009. Male patient, child 3 years of age, weighting 37.48 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: agitation, anxiety , blood pressure decreased, bronchospasm, cyanosis, fatigue, feeding tube complication, flushing, heart rate increased. Myozyme dosage: 350 MG, Q2W, INTRAVENOUS. During the same period patient was treated with BENADRYL, ACETAMINOPHEN, DECADRON. Patient recovered.

Myozyme Side Effects Report #6101010-9
Myozyme side effect was reported by a Physician from UNITED STATES on Feb 17, 2009. Male patient, child 3 years of age, weighting 37.48 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: agitation, anxiety , blood pressure decreased, bronchospasm, cyanosis, fatigue, flushing, heart rate increased, hypoxia. Myozyme dosage: 350 MG, Q2W, INTRAVENOUS. During the same period patient was treated with BENADRYL, ACETAMINOPHEN, DECADRON. Patient recovered.

Myozyme Side Effects Report #6125057-1
Myozyme side effect was reported by a Physician from UNITED STATES on Mar 05, 2009. Male patient, child 3 years of age, weighting 37.48 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: agitation, antibody test positive, anxiety , blood pressure decreased, bronchospasm, cyanosis, fatigue, flushing, hypoxia. Myozyme dosage: 350 MG, Q2W, INTRAVENOUS. During the same period patient was treated with BENADRYL, ACETAMINOPHEN, DECADRON. Patient recovered.


Myozyme Side Effects Report #6137899-7
Myozyme side effect was reported by a Physician from UNITED STATES on Mar 17, 2009. Male patient, child 3 years of age, weighting 37.48 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: agitation, anxiety , blood pressure decreased, bronchospasm, cyanosis, fatigue, flushing, heart rate increased, hypoxia. Myozyme dosage: 350 MG, Q2W, INTRAVENOUS. During the same period patient was treated with BENADRYL, ACETAMINOPHEN, DECADRON. Patient recovered.

Myozyme Side Effects Report #5935024-6
Myozyme side effect was reported by a Physician from ISRAEL on Oct 15, 2008. Male patient, child 2 years of age, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: cardiac hypertrophy, cardiomyopathy , central line infection, cyanosis, deafness neurosensory, disease progression, electromyogram abnormal, hypotension, hypotonia. Myozyme dosage: 20 MG/KG, Q2W, INTRAVENOUS. During the same period patient was treated with CORTICOSTEROIDS, PHENERGAN, HYDROCORTISONE. Patient was hospitalized and became disabled. Patient recovered.

Myozyme Side Effects Report #6023234-1
Myozyme side effect was reported by a Physician from ISRAEL on Dec 11, 2008. Male patient, child 2 years of age, weighting 26.46 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: acute respiratory failure, cardiac hypertrophy, cardiomyopathy , central line infection, cough, cyanosis, deafness neurosensory, disease progression, electromyogram abnormal. Myozyme dosage: 20 MG/KG, Q2W, INTRAVENOUS. During the same period patient was treated with CORTICOSTEROIDS, PHENERGAN, HYDROCORTISONE. Patient was hospitalized and became disabled. Patient recovered.

Myozyme Side Effects Report #6032049-X
Myozyme side effect was reported by a Physician from ISRAEL on Dec 24, 2008. Male patient, child 2 years of age, weighting 26.46 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: acute respiratory failure, alanine aminotransferase increased, aspartate aminotransferase increased, blood creatine phosphokinase increased, blood lactate dehydrogenase increased, cardiac hypertrophy, central line infection, cyanosis, deafness neurosensory. Myozyme dosage: 20 MG/KG, Q2W, INTRAVENOUS. During the same period patient was treated with CORTICOSTEROIDS, PHENERGAN, HYDROCORTISONE, ASPIRIN. Patient was hospitalized and became disabled. Patient recovered.

Myozyme Side Effects Report #6081259-4
Myozyme side effect was reported by a Physician from UNITED STATES on Feb 02, 2009. Female patient, child 2 years of age, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: bradycardia, cardiac disorder, cyanosis, oxygen saturation decreased, respiratory arrest. Myozyme dosage: 20 MG/KG, Q2W, INTRAVENOUS. Patient died on 02/02/2009.


Myozyme Side Effects Report #5081199-3
Myozyme side effect was reported by a Physician from UNITED STATES on July 27, 2006. Male patient, 14 years of age, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: blood pressure increased, bronchospasm, chest discomfort, chills, cyanosis, flushing, infusion related reaction, tachycardia, tachypnoea. Myozyme dosage: 20 MG/KG Q2WKS IV. During the same period patient was treated with ALPHA, BENADRYL, TYLENOL, STEROID. Patient recovered.

Myozyme Side Effects Report #5454998-3
Myozyme side effect was reported by a Physician from CHINA on Aug 30, 2007. Female patient, child 1 years of age, weighting 13.87 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: blood pressure decreased, cardiac failure, condition aggravated, cyanosis, disease recurrence, fluid overload, hyperhidrosis, myocardial ischaemia, nodal arrhythmia. Myozyme dosage: 20 MG/KG Q2WKS IV. During the same period patient was treated with CAPTOPRIL, FRUSEMIDE. Patient recovered.

Myozyme Side Effects Report #5460684-6
Myozyme side effect was reported by a Physician from BRAZIL on Sept 04, 2007. Male patient, child 1 years of age, weighting 21.58 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: atelectasis, body temperature increased, bronchospasm, cyanosis, hyperhidrosis, hypertrophic cardiomyopathy, pallor, palmar erythema, peripheral coldness. Myozyme dosage: 20 MG/KG Q2WKS IV. During the same period patient was treated with ALPHA, PROPRANOLOL, CAPTOPRIL. Patient recovered.

Myozyme Side Effects Report #5460687-1
Myozyme side effect was reported by a Physician from BRAZIL on Sept 04, 2007. Male patient, child 1 years of age, weighting 21.23 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: crying, cyanosis, lethargy, nausea , oxygen saturation decreased, pallor, palmar erythema, rash , tachycardia. Myozyme dosage: 20 MG/KG IV. During the same period patient was treated with PROPRANOLOL, CAPTOPRIL. Patient was hospitalized. Patient recovered.

Myozyme Side Effects Report #5518847-7
Myozyme side effect was reported by a Physician from SPAIN on Oct 29, 2007. Male patient, child 1 years of age, weighting 27.56 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: anaphylactic reaction, cyanosis, disease recurrence, dyspnoea, infusion related reaction, nasopharyngitis, respiratory arrest, respiratory tract infection, transaminases increased. Myozyme dosage: 20 MG/KG Q2WKS IV. During the same period patient was treated with ACTOCORTINA, SPIRONOLACTONE, CARVEDILOL. Patient recovered.


Myozyme Side Effects Report #5285767-5
Myozyme side effect was reported by a Physician from UNITED STATES on Sept 29, 2006. Male patient was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: chills, cyanosis, dyskinesia, hyperhidrosis, tachycardia. Myozyme dosage: 20 MG/KG Q2WKS IV. During the same period patient was treated with ALPHA, TYLENOL, BENADRYL. Patient recovered.

Myozyme Side Effects Report #5229673-0
Myozyme side effect was reported by a Physician from GREECE on Jan 18, 2007. Female patient, weighting 17.64 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: abdominal infection, alanine aminotransferase increased, aspartate aminotransferase increased, blood immunoglobulin g increased, cardio-respiratory arrest, cardiopulmonary failure, cyanosis, diarrhoea, dilatation ventricular. Myozyme dosage: 20 MG/KG QWK IV. During the same period patient was treated with ALPHA, HCL THIAZIDE, SPIRONOLACTONE, DIGITALIS, ENALAPRIL MALEATE. Patient was hospitalized. Patient died on 12/29/2006.

Myozyme Side Effects Report #5255199-4
Myozyme side effect was reported by a Physician from ITALY on Feb 14, 2007. Female patient, weighting 14.33 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: central line infection, cyanosis, hypotension, oxygen saturation decreased, viral infection . Myozyme dosage: 20 MG/KG Q2WKS IV. Patient recovered.

Myozyme Side Effects Report #5268621-4
Myozyme side effect was reported by a Physician from BRAZIL on Feb 28, 2007. Female patient, weighting 16.31 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: bradycardia, brain oedema, cardiogenic shock, cardiomyopathy , cyanosis, disease progression, pyrexia, tachycardia. Myozyme dosage: 20 MG/KG Q2WKS IV. During the same period patient was treated with CARVEDILOL, CAPTOPRIL. Patient died on 02/13/2007.

Myozyme Side Effects Report #5290127-7
Myozyme side effect was reported by a Physician from GREECE on Mar 16, 2007. Female patient, weighting 17.64 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: abdominal infection, alanine aminotransferase increased, antibody test positive, aspartate aminotransferase increased, cardio-respiratory arrest, cardiopulmonary failure, cyanosis, diarrhoea, disease progression. Myozyme dosage: 20 MG/KG QWK IV. During the same period patient was treated with ALPHA, HCL THIAZIDE, SPIRONOLACTONE, DIGITALIS, ENALAPRIL MALEATE. Patient was hospitalized. Patient died on 12/29/2006.


Myozyme Side Effects Report #5291323-5
Myozyme side effect was reported by a Physician from BRAZIL on Mar 20, 2007. Female patient, weighting 16.31 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: bradycardia, brain herniation, brain oedema, cardiogenic shock, cyanosis, disease progression, gastrointestinal haemorrhage, haematocrit decreased, haemoglobin decreased. Myozyme dosage: 20 MG/KG Q2WKS IV. During the same period patient was treated with CARVEDILOL, CAPTOPRIL, RANITIDINE, PROTOVIT, FERROUS SULPHATE, ASCORBIC ACID, ZINC SULPHATE. Patient died on 02/13/2007.

Myozyme Side Effects Report #5293817-5
Myozyme side effect was reported by a Physician from ITALY on Mar 22, 2007. Female patient, weighting 14.33 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: central line infection, cyanosis, hypotension, infusion related reaction, oxygen saturation decreased. Myozyme dosage: 20 MG/KG Q2WKS IV. Patient recovered.

Myozyme Side Effects Report #5094039-3
Myozyme side effect was reported by a Physician from SPAIN on Aug 18, 2006. Male patient, weighting 18.08 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: cyanosis, respiratory arrest, respiratory failure, urticaria. Myozyme dosage: 20 MG/KG Q2WKS IV. During the same period patient was treated with FUROSEMIDE, HYDROCHLOROTHIAZIDE, CARVEDILOL. Patient was hospitalized. Patient recovered.

Myozyme Side Effects Report #5097560-7
Myozyme side effect was reported by a Physician from BRAZIL on Aug 18, 2006. Male patient, weighting 19.82 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: bronchospasm, cyanosis, infusion related reaction, pallor, rash , vomiting. Myozyme dosage: 20 MG/KG IV. During the same period patient was treated with PROPRANOLOL, CAPTOPRIL, LASIX. Patient recovered.

Myozyme Side Effects Report #5106859-7
Myozyme side effect was reported by a Physician from BRAZIL on Aug 31, 2006. Male patient, weighting 19.82 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: bronchospasm, complement factor increased, cyanosis, erythema, infusion related reaction, lethargy, oxygen saturation decreased, pallor, rash . Myozyme dosage: 20 MG/KG IV. During the same period patient was treated with PROPRANOLOL, CAPTOPRIL, LASIX. Patient recovered.


Myozyme Side Effects Report #5205587-7
Myozyme side effect was reported by a Physician from UNITED STATES on Sept 27, 2006. Male patient was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: chills, cyanosis, dyskinesia, hyperhidrosis, tachycardia. Myozyme dosage: 20 MG/KG Q2WKS; IV. During the same period patient was treated with ALPHA, TYLENOL, BENADRYL. Patient recovered.

Myozyme Side Effects Report #5159354-3
Myozyme side effect was reported by a Physician from SPAIN on Nov 06, 2006. Male patient, weighting 18.08 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: cyanosis, dyspnoea, respiratory arrest, respiratory failure, urticaria. Myozyme dosage: 20 MG/KG Q2WKS IV. During the same period patient was treated with FUROSEMIDE, HYDROCHLOROTHIAZIDE, CARVEDILOL. Patient was hospitalized. Patient recovered.

Myozyme Side Effects Report #5169331-4
Myozyme side effect was reported by a Physician from BRAZIL on Nov 17, 2006. Male patient, weighting 21.23 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: crying, cyanosis, lethargy, pallor, tremor. Myozyme dosage: 20 MG/KG IV. During the same period patient was treated with PROPRANOLOL, CAPTOPRIL. Patient was hospitalized. Patient recovered.

Myozyme Side Effects Report #5449823-0
Myozyme side effect was reported by a Physician from SPAIN on Aug 27, 2007. Male patient, weighting 27.56 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: anaphylactic reaction, bronchospasm, cyanosis, dyspnoea, hyperhidrosis, infusion related reaction, lip oedema, nasopharyngitis, pharyngeal oedema. Myozyme dosage: 20 MG/KG Q2WKS IV. During the same period patient was treated with ALPHA, ACTOCORTINA, SPIRONOLACTONE, CARVEDILOL. Patient recovered.

Myozyme Side Effects Report #5635628-4
Myozyme side effect was reported by a Physician from FRANCE on Feb 05, 2008. Female patient, weighting 13.67 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: apnoea, crying, cyanosis, dyspnoea, erythema, infusion related reaction, moaning, nervousness, pyrexia. Myozyme dosage: 20 MG/KG, Q2W, INTRAVENOUS. Patient recovered.


Myozyme Side Effects Report #5663287-3
Myozyme side effect was reported by a Physician from BRAZIL on Feb 26, 2008. Male patient was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: circulatory collapse, convulsion, cyanosis, diarrhoea. Myozyme dosage: 20 MG/KG, Q2W. During the same period patient was treated with CAPTOPRIL, FUROSEMIDE. Patient was hospitalized. Patient recovered.

Myozyme Side Effects Report #5678162-8
Myozyme side effect was reported by a Physician from FRANCE on Mar 05, 2008. Female patient, weighting 13.67 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: apnoea, cyanosis, dyspnoea, erythema, hyperthermia, infusion related reaction, lacrimation increased, moaning, nervousness. Myozyme dosage: 20 MG/KG, Q2W, INTRAVENOUS. During the same period patient was treated with LASIX, LEVOCARNIL, DEXTRIN. Patient recovered.

Myozyme Side Effects Report #5679713-X
Myozyme side effect was reported by a Physician from BRAZIL on Mar 07, 2008. Male patient was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: brain hypoxia, cardiac arrest , circulatory collapse, convulsion, cyanosis, diarrhoea. Myozyme dosage: 20 MG/KG, Q2W. During the same period patient was treated with CAPTOPRIL, FUROSEMIDE. Patient was hospitalized. Patient died on 03/06/2008.

Myozyme Side Effects Report #5679717-7
Myozyme side effect was reported by a Physician from BRAZIL on Mar 07, 2008. Male patient was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: brain hypoxia, cardiac arrest , circulatory collapse, convulsion, cyanosis, diarrhoea, haemodynamic instability. Myozyme dosage: 20 MG/KG, Q2W. During the same period patient was treated with CAPTOPRIL, FUROSEMIDE. Patient was hospitalized. Patient died on 03/06/2008.

Myozyme Side Effects Report #5689669-1
Myozyme side effect was reported by a Physician from SPAIN on Mar 13, 2008. Male patient, weighting 27.56 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: anaphylactic reaction, bronchospasm, cardiac failure, cyanosis, infusion related reaction, nasopharyngitis, respiratory arrest, respiratory failure, transaminases increased. Myozyme dosage: 20 MG/KG, Q2W, INTRAVENOUS; 40 MG/KG, Q2W, INTRAVENOUS; 20 MG/KG, Q2W, INTRAVENOUS. Patient died on 02/01/2008.

Myozyme Side Effects Report #5714330-4
Myozyme side effect was reported by a Physician from ISRAEL on Apr 10, 2008. Male patient, weighting 21.83 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: bronchospasm, cyanosis, dyspnoea, hypersensitivity, oxygen saturation decreased. Myozyme dosage: 200 MG, Q2W, INTRAVENOUS. During the same period patient was treated with FUROSEMIDE, CAPTOPRIL. Patient recovered.

Myozyme Side Effects Report #5724268-4
Myozyme side effect was reported by a Physician from FRANCE on Apr 21, 2008. Female patient, weighting 13.67 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: apnoea, crying, cyanosis, dyspnoea, erythema, hyperthermia, moaning, nervousness. Myozyme dosage: 20 MG/KG, Q2W, INTRAVENOUS. During the same period patient was treated with LASIX, LEVOCARNIL, DEXTRIN. Patient recovered.

Myozyme Side Effects Report #5724720-1
Myozyme side effect was reported by a Health Professional from ISRAEL on Apr 18, 2008. Male patient, weighting 21.83 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: bronchospasm, cyanosis, dyspnoea, hypersensitivity, oxygen saturation decreased. Myozyme dosage: 200 MG, Q2W, INTRAVENOUS. During the same period patient was treated with FUROSEMIDE, CAPTOPRIL. Patient recovered.

Myozyme Side Effects Report #5729660-X
Myozyme side effect was reported by a Physician from ISRAEL on Apr 21, 2008. Male patient was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: cardiac hypertrophy, central line infection, cyanosis, deafness neurosensory, disease progression, dysstasia, electromyogram abnormal, hypotension. Myozyme dosage: unknown. During the same period patient was treated with CORTICOSTEROIDS, PHENERGAN, HYDROCORTISONE. Patient was hospitalized and became disabled. Patient recovered.

Myozyme Side Effects Report #5747234-1
Myozyme side effect was reported by a Physician from ISRAEL on Apr 27, 2008. Male patient, weighting 21.83 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: bronchospasm, cyanosis, dyspnoea, hypersensitivity, oxygen saturation decreased. Myozyme dosage: 200 MG, Q2W, INTRAVENOUS. During the same period patient was treated with FUROSEMIDE, CAPTOPRIL. Patient recovered.


Myozyme Side Effects Report #5768470-4
Myozyme side effect was reported by a Physician from ISRAEL on June 03, 2008. Male patient was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: cardiac hypertrophy, central line infection, cyanosis, deafness neurosensory, disease progression, electromyogram abnormal, hypotension, hypotonia. Myozyme dosage: unknown. During the same period patient was treated with CORTICOSTEROIDS, PHENERGAN, HYDROCORTISONE. Patient was hospitalized and became disabled. Patient recovered.

Myozyme Side Effects Report #6055095-9
Myozyme side effect was reported by a Physician from GREECE on Jan 15, 2009. Male patient, weighting 17.64 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: blood pressure decreased, cyanosis, hypersensitivity, infusion related reaction. Myozyme dosage: 20 MG/KG, Q2W, INTRAVENOUS. Patient recovered.

Myozyme Side Effects Report #6077626-5
Myozyme side effect was reported by a Physician from GREECE on Jan 29, 2009. Male patient, weighting 17.64 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: blood pressure decreased, cyanosis, infusion related reaction, tryptase increased. Myozyme dosage: 20 MG/KG, Q2W, INTRAVENOUS. Patient was hospitalized. Patient recovered.

Myozyme Side Effects Report #6088518-X
Myozyme side effect was reported by a Physician from GREECE on Feb 12, 2009. Male patient, weighting 17.64 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: blood pressure decreased, cyanosis, infusion related reaction. Myozyme dosage: 20 MG/KG, Q2W, INTRAVENOUS. Patient was hospitalized. Patient recovered.

Myozyme Side Effects Report #6094701-X
Myozyme side effect was reported by a Physician from GREECE on Feb 13, 2009. Male patient, weighting 17.64 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: blood pressure decreased, cyanosis, disease recurrence, hypersensitivity, infusion related reaction. Myozyme dosage: 20 MG/KG, Q2W, INTRAVENOUS. Patient was hospitalized. Patient recovered.

Myozyme Side Effects Report #6111297-4
Myozyme side effect was reported by a Physician from GREECE on Feb 27, 2009. Male patient, weighting 17.64 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: cyanosis, erythema, hypersensitivity, hypotension, infusion related reaction, pruritus, rash . Myozyme dosage: 20 MG/KG, Q2W, INTRAVENOUS. Patient was hospitalized. Patient recovered.