Penfill and anti-insulin antibody Patient Reports February 10, 2010

Penfill Side Effects Report #5972661-7
Penfill side effect was reported by a Physician from JAPAN on Nov 20, 2008. Male patient, 68 years of age, was diagnosed with type 2 diabetes mellitus and was treated with Penfill. After drug was administered, patient experienced the following side effects: anti-insulin antibody, hypoglycaemia. Penfill dosage: unknown. During the same period patient was treated with PENFILL R CHU, PENFILL N CHU, PENFILL R CHU, HUMALOG. Patient was hospitalized. Patient recovered.

Penfill Side Effects Report #5501550-7
Penfill side effect was reported by a Physician from JAPAN on Oct 22, 2007. Female patient, 77 years of age, was diagnosed with insulin-requiring type ii diabetes mellitus and was treated with Penfill. After drug was administered, patient experienced the following side effects: anti-insulin antibody, blood glucose fluctuation. Penfill dosage: unknown. During the same period patient was treated with NOVORAPID, NOVORAPID CHU. Patient was hospitalized. Patient recovered.

Penfill Side Effects Report #5576811-6
Penfill side effect was reported by a Consumer or non-health professional from JAPAN on Dec 19, 2007. Female patient, 77 years of age, was diagnosed with insulin-requiring type ii diabetes mellitus and was treated with Penfill. After drug was administered, patient experienced the following side effects: anti-insulin antibody, blood glucose fluctuation. Penfill dosage: unknown. During the same period patient was treated with NOVORAPID, NOVORAPID CHU. Patient was hospitalized. Patient recovered.

Penfill Side Effects Report #5507647-X
Penfill side effect was reported by a Physician from JAPAN on Oct 24, 2007. Female patient, 58 years of age, was diagnosed with diabetes mellitus and was treated with Penfill. After drug was administered, patient experienced the following side effects: anti-insulin antibody, autoantibody positive, bladder perforation, blood glucose fluctuation. Penfill dosage: unknown. Patient was hospitalized. Patient recovered.


Penfill Side Effects Report #5514229-2
Penfill side effect was reported by a Physician from JAPAN on Nov 02, 2007. Female patient, 58 years of age, was diagnosed with diabetes mellitus and was treated with Penfill. After drug was administered, patient experienced the following side effects: anti-insulin antibody, autoantibody positive, bladder perforation, blood glucose fluctuation. Penfill dosage: unknown. Patient was hospitalized. Patient recovered.