Posaconazole and alanine aminotransferase increased Patient Reports March 20, 2010

Posaconazole Side Effects Report #6068442-9
Posaconazole side effect was reported by a Physician from GERMANY on Jan 26, 2009. Male patient, child 4 years of age, weighting 44.09 lb, was diagnosed with prophylaxis, acute lymphocytic leukaemia and was treated with Posaconazole. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, gamma-glutamyltransferase increased, lymphoedema, puncture site infection, transaminases increased. Posaconazole dosage: 120 MG;BID;PO. During the same period patient was treated with METHOTREXATE, VINDESINE, IFOSFAMIDE, GRANISETRON, DEXAMETHASONE, FLUCONAZOLE, COTRIM. Patient was hospitalized. Patient recovered.

Posaconazole Side Effects Report #6074496-6
Posaconazole side effect was reported by a Physician from GERMANY on Jan 30, 2009. Male patient, child 4 years of age, weighting 44.09 lb, was diagnosed with prophylaxis, acute lymphocytic leukaemia and was treated with Posaconazole. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, gamma-glutamyltransferase increased, haematocrit decreased, haemoglobin decreased, lymphocyte percentage decreased, neutrophil percentage increased, puncture site infection. Posaconazole dosage: 120 MG; BID; PO. During the same period patient was treated with METHOTREXATE, VINDESINE, IFOSFAMIDE, GRANISETRON, DEXAMETHASONE, FLUCONAZOL, COTRIM. Patient was hospitalized. Patient recovered.

Posaconazole Side Effects Report #5326536-7
Posaconazole side effect was reported by a Physician from UNITED STATES on May 04, 2007. Male patient, 20 years of age, weighting 123.5 lb, was diagnosed with fungal infection  and was treated with Posaconazole. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood alkaline phosphatase increased, cholelithiasis, dehydration, hyperbilirubinaemia, hypoalbuminaemia, hypotension, oral intake reduced. Posaconazole dosage: 400 MG; BID; PO. During the same period patient was treated with ZENERGAN, DEPAKENE, MEGACE, FOLIC ACID, PREVACID. Patient was hospitalized. Patient recovered.

Posaconazole Side Effects Report #6035325-X
Posaconazole side effect was reported by a Physician from GERMANY on Dec 25, 2008. Male patient, child 4 years of age, weighting 44.09 lb, was diagnosed with acute lymphocytic leukaemia, prophylaxis and was treated with Posaconazole. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, gamma-glutamyltransferase increased. Posaconazole dosage: 120 MG;BID;PO. During the same period patient was treated with METHOTREXATE, VINDESINE, IFOSFAMIDE, GRANISETRON, DEXAMETHASONE, FLUCONAZOLE, COTRIM. Patient was hospitalized. Patient recovered.


Posaconazole Side Effects Report #6053152-4
Posaconazole side effect was reported by a Physician from GERMANY on Jan 14, 2009. Male patient, child 4 years of age, weighting 44.09 lb, was diagnosed with acute lymphocytic leukaemia, prophylaxis and was treated with Posaconazole. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, gamma-glutamyltransferase increased, puncture site infection. Posaconazole dosage: 120 MG; BID; PO. During the same period patient was treated with METHOTREXATE, VINDESINE, IFOSFAMIDE, GRANISETRON, DEXAMETHASONE, FLUCONAZOLE, COTRIM. Patient was hospitalized. Patient recovered.