Prograf and graft versus host disease Patient Reports February 10, 2010

Prograf Side Effects Report #5679943-7
Prograf side effect was reported by a Physician from JAPAN on Mar 07, 2008. Male patient, child 9 years of age, was diagnosed with stem cell transplant and was treated with Prograf. After drug was administered, patient experienced the following side effects: abdominal pain , graft versus host disease, myocarditis, ventricular fibrillation, vomiting. Prograf dosage: unknown. During the same period patient was treated with PREDNISOLONE. Patient died.

Prograf Side Effects Report #5176539-0
Prograf side effect was reported by a Physician from GERMANY on Nov 28, 2006. Male patient, 64 years of age, was diagnosed with stem cell transplant and was treated with Prograf. After drug was administered, patient experienced the following side effects: cachexia, conjunctivitis, diarrhoea, duodenitis, graft versus host disease, pancytopenia, pneumonia , rash maculo-papular, sicca syndrome. Prograf dosage: unknown. During the same period patient was treated with CYCLOSPORINE, CORTICOSTEROIDS. Patient was hospitalized. Patient died.

Prograf Side Effects Report #5805150-0
Prograf side effect was reported by a Consumer or non-health professional from UNITED STATES on June 20, 2008. Female patient, 60 years of age, was diagnosed with stem cell transplant and was treated with Prograf. After drug was administered, patient experienced the following side effects: graft versus host disease, lung disorder, organising pneumonia. Prograf dosage: unknown. Patient recovered.

Prograf Side Effects Report #5305462-3
Prograf side effect was reported by a Physician from JAPAN on Mar 29, 2007. Male patient, 58 years of age, was diagnosed with stem cell transplant and was treated with Prograf. After drug was administered, patient experienced the following side effects: depressed level of consciousness, graft versus host disease, hepatic failure, human herpesvirus 6 infection, liver disorder. Prograf dosage: unknown. During the same period patient was treated with ACYCLOVIR. Patient died.


Prograf Side Effects Report #5319718-1
Prograf side effect was reported by a Physician from JAPAN on Apr 16, 2007. Male patient, 58 years of age, weighting 159.8 lb, was diagnosed with stem cell transplant and was treated with Prograf. After drug was administered, patient experienced the following side effects: acute graft versus host disease in liver, bone marrow transplant , bronchopulmonary aspergillosis, depressed level of consciousness, hepatic failure, human herpesvirus 6 infection, oral candidiasis. Prograf dosage: unknown. During the same period patient was treated with ACYCLOVIR, TEICOPLANINECTION, MILLISROL, NOVOLIN R, FUNGUARD, FLUDARA, ALKERAN. Patient died on 01/06/2005.

Prograf Side Effects Report #4900780-2
Prograf side effect was reported by a Physician from GERMANY on Jan 23, 2006. Male patient, 56 years of age, was diagnosed with stem cell transplant and was treated with Prograf. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, blood alkaline phosphatase increased, gamma-glutamyltransferase increased, graft versus host disease, haemoglobin decreased, haemosiderosis, muscle atrophy, myopathy. Prograf dosage: unknown. During the same period patient was treated with CORTICOSTEROIDS, AZATHIOPRINE, CYCLOSPORINE, MYCOPHENOLATE MOFETIL, METHOTREXATE, THALIDOMIDE. Patient was hospitalized. Patient died.

Prograf Side Effects Report #5542812-7
Prograf side effect was reported by a Physician from UNITED STATES on Nov 27, 2007. Female patient, 55 years of age, was diagnosed with stem cell transplant and was treated with Prograf. After drug was administered, patient experienced the following side effects: acute graft versus host disease in skin. Prograf dosage: unknown. During the same period patient was treated with PREDNISOLONE ACETATE, MYCOPHENOLATE MOFETIL. Patient recovered.

Prograf Side Effects Report #5542729-8
Prograf side effect was reported by a Physician from UNITED STATES on Nov 27, 2007. Female patient, 54 years of age, was diagnosed with stem cell transplant and was treated with Prograf. After drug was administered, patient experienced the following side effects: acute graft versus host disease in liver, acute graft versus host disease in skin. Prograf dosage: unknown. During the same period patient was treated with PREDNISOLONE ACETATE, MYCOPHENOLATE MOFETIL, SIROLIMUS. Patient died.

Prograf Side Effects Report #5674507-3
Prograf side effect was reported by a Physician from JAPAN on Feb 29, 2008. Male patient, 51 years of age, was diagnosed with stem cell transplant and was treated with Prograf. After drug was administered, patient experienced the following side effects: aspergillosis, graft versus host disease. Prograf dosage: unknown. During the same period patient was treated with METHOTREXATE, GRANULOCYTE COLONY STIMULATING FACTOR, MELPHALAN, PREDNISOLONE. Patient died.


Prograf Side Effects Report #5542788-2
Prograf side effect was reported by a Physician from UNITED STATES on Nov 27, 2007. Male patient, 49 years of age, was diagnosed with stem cell transplant and was treated with Prograf. After drug was administered, patient experienced the following side effects: acute graft versus host disease in skin, hepatic enzyme increased. Prograf dosage: unknown. During the same period patient was treated with PREDNISOLONE ACETATE, MYCOPHENOLATE MOFETIL. Patient recovered.

Prograf Side Effects Report #5646321-6
Prograf side effect was reported by a Health Professional from CANADA on Feb 18, 2008. Male patient, 47 years of age, weighting 184.7 lb, was diagnosed with stem cell transplant, prophylaxis and was treated with Prograf. After drug was administered, patient experienced the following side effects: autoimmune hepatitis, clostridium difficile colitis, dehydration, graft versus host disease, haemodialysis, hepatic cirrhosis, hepatorenal syndrome, pancytopenia. Prograf dosage: unknown. During the same period patient was treated with VORICONAZOLE, METRONIDAZOL, RABEPRAZOLE, LOPERAMIDE. Patient was hospitalized. Patient recovered.

Prograf Side Effects Report #5679578-6
Prograf side effect was reported by a Health Professional from CANADA on Mar 11, 2008. Male patient, 47 years of age, weighting 184.7 lb, was diagnosed with stem cell transplant, prophylaxis and was treated with Prograf. After drug was administered, patient experienced the following side effects: autoimmune hepatitis, blood creatinine increased, clostridial infection, disease complication, enterobacter infection, graft versus host disease, haemodialysis, hepatic cirrhosis. Prograf dosage: unknown. During the same period patient was treated with VORICONAZOLE, METRONIDAZOLE, RABEPRAZOLE, LOPERAMIDE. Patient was hospitalized. Patient died on 02/23/2008.

Prograf Side Effects Report #5246208-7
Prograf side effect was reported by a Physician from JAPAN on Feb 05, 2007. Female patient, 45 years of age, was diagnosed with stem cell transplant and was treated with Prograf. After drug was administered, patient experienced the following side effects: cardio-respiratory arrest, coma, convulsion, encephalitis herpes, graft versus host disease, leukoencephalopathy, nephropathy toxic, rash . Prograf dosage: unknown. During the same period patient was treated with THIOTEPA, CYCLOPHOSPHAMIDE, ACYCLOVIR. Patient died.

Prograf Side Effects Report #6071263-4
Prograf side effect was reported by a Physician from JAPAN on Jan 27, 2009. Male patient, 44 years of age, was diagnosed with stem cell transplant and was treated with Prograf. After drug was administered, patient experienced the following side effects: adrenal haemorrhage, atrophy, blood pressure decreased, congestive cardiomyopathy, disseminated intravascular coagulation, graft versus host disease, pneumococcal sepsis, spleen disorder. Prograf dosage: /D; 0.5 MG, QOD. During the same period patient was treated with STEROIDMULATION, ANTIBIOTIC, PANIPENEM, BETAMIPRON. Patient died.


Prograf Side Effects Report #5897818-5
Prograf side effect was reported by a Physician from JAPAN on Sept 19, 2008. Male patient, 42 years of age, weighting 142.2 lb, was diagnosed with stem cell transplant and was treated with Prograf. After drug was administered, patient experienced the following side effects: blood pressure systolic decreased, bone marrow failure, bronchopulmonary aspergillosis, depressed level of consciousness, diarrhoea, disease progression, graft versus host disease, heart rate increased, histiocytosis haematophagic. Prograf dosage: 3 MG, CONTINUOUS, IV DRIP. During the same period patient was treated with CELLCEPT, PREDNISOLONE. Patient died on 11/11/2007.

Prograf Side Effects Report #5542822-X
Prograf side effect was reported by a Physician from UNITED STATES on Nov 27, 2007. Male patient, 36 years of age, was diagnosed with stem cell transplant and was treated with Prograf. After drug was administered, patient experienced the following side effects: acute graft versus host disease in skin. Prograf dosage: unknown. During the same period patient was treated with PREDNISOLONE ACETATE, MYCOPHENOLATE MOFETIL. Patient recovered.

Prograf Side Effects Report #5633048-X
Prograf side effect was reported by a Physician from JAPAN on Jan 29, 2008. Female patient, 31 years of age, was diagnosed with stem cell transplant and was treated with Prograf. After drug was administered, patient experienced the following side effects: bronchopulmonary aspergillosis, cytomegalovirus infection , diabetes mellitus, diabetic ketoacidosis, enterobacter sepsis, febrile neutropenia, graft versus host disease, respiratory failure. Prograf dosage: 0.02 MG/KG, D. During the same period patient was treated with METHOTREXATE, METHYLPREDNISOLONE, GANCICLOVIR, TOSUFLOXACIN, FLUCONAZOLE, TRIMETOPRIM, MEROPENEM. Patient died.

Prograf Side Effects Report #5542913-3
Prograf side effect was reported by a Physician from UNITED STATES on Nov 27, 2007. Male patient, 26 years of age, was diagnosed with stem cell transplant and was treated with Prograf. After drug was administered, patient experienced the following side effects: acute graft versus host disease in liver, acute graft versus host disease in skin, arthropathy. Prograf dosage: unknown. During the same period patient was treated with PREDNISOLONE ACETATE, HYDROXYCHLOROQUINE SULPHATE, SIROLIMUS, QUININE. Patient recovered.

Prograf Side Effects Report #4877473-3
Prograf side effect was reported by a Physician from JAPAN on Dec 27, 2005. Male patient, 23 years of age, weighting 108.2 lb, was diagnosed with stem cell transplant and was treated with Prograf. After drug was administered, patient experienced the following side effects: atypical mycobacterial infection, cryptogenic organizing pneumonia, graft versus host disease, leukaemia recurrent, obliterative bronchiolitis, pneumonia bacterial, pneumonia fungal, respiratory failure. Prograf dosage: unknown. Patient was hospitalized. Patient died on 09/09/2004.


Prograf Side Effects Report #4905459-9
Prograf side effect was reported by a Physician from JAPAN on Jan 25, 2006. Male patient, 23 years of age, weighting 108.2 lb, was diagnosed with stem cell transplant and was treated with Prograf. After drug was administered, patient experienced the following side effects: atypical mycobacterial infection, complications of transplant surgery, cryptogenic organizing pneumonia, graft versus host disease, leukaemia, obliterative bronchiolitis, pneumonia bacterial, respiratory failure. Prograf dosage: unknown. Patient was hospitalized. Patient died on 09/09/2004.

Prograf Side Effects Report #5291925-6
Prograf side effect was reported by a Physician from JAPAN on Mar 19, 2007. Male patient, 20 years of age, weighting 154.3 lb, was diagnosed with stem cell transplant and was treated with Prograf. After drug was administered, patient experienced the following side effects: adenovirus infection, convulsion, cystitis haemorrhagic, graft versus host disease, kidney infection, melaena, pain , urine output decreased. Prograf dosage: unknown. During the same period patient was treated with NEUTROGIN, PREDNISOLONE, CARBENIN, HABEKACIN, DIFLUCAN. Patient died on 08/12/1998.

Prograf Side Effects Report #5376224-6
Prograf side effect was reported by a Physician from JAPAN on June 18, 2007. Male patient, weighting 11.68 lb, was diagnosed with stem cell transplant and was treated with Prograf. After drug was administered, patient experienced the following side effects: aspergillosis, bronchitis moraxella, complications of bone marrow transplant, fungal endocarditis, graft versus host disease, infection in an immunocompromised host. Prograf dosage: 0.1 MG, BID, ORAL. During the same period patient was treated with PREDNISOLONE, METHOTREXATE, SULFAMETHOXAZOLE AND TRIMETHOPRIM, TEICOPLANIN, MEROPENEM, FLUCONAZOLE, FUNGUARD. Patient was hospitalized. Patient recovered.

Prograf Side Effects Report #5699317-2
Prograf side effect was reported by a Health Professional from UNITED STATES on Mar 26, 2008. Male patient, 54 years of age, was diagnosed with renal transplant and was treated with Prograf. After drug was administered, patient experienced the following side effects: cytomegalovirus infection , deep vein thrombosis , epidermal necrosis, graft versus host disease, hyperkeratosis, lymphocytic infiltration, multi-organ failure, night sweats. Prograf dosage: unknown. During the same period patient was treated with ANTITHYMOCYTE IMMUNOGLOBULIN, PREDNISONE, MYCOPHENOLATE MOFETIL. Patient was hospitalized. Patient died.

Prograf Side Effects Report #4696268-7
Prograf side effect was reported by a Physician from on June 08, 2005. Male patient, 68 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Prograf. After drug was administered, patient experienced the following side effects: diarrhoea, graft versus host disease, multi-organ failure, neutropenia, rash maculo-papular, renal failure acute, respiratory failure. Prograf dosage: unknown. Patient died.


Prograf Side Effects Report #5009512-3
Prograf side effect was reported by a Consumer or non-health professional from UNITED STATES on May 05, 2006. Male patient, 63 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Prograf. After drug was administered, patient experienced the following side effects: cataract , graft versus host disease, herpes simplex ophthalmic. Prograf dosage: 8 MG, UID/QD. During the same period patient was treated with PREDNISONE. Patient recovered.

Prograf Side Effects Report #5035784-5
Prograf side effect was reported by a Consumer or non-health professional from UNITED STATES on June 09, 2006. Male patient, 63 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Prograf. After drug was administered, patient experienced the following side effects: cataract , graft versus host disease, herpes simplex . Prograf dosage: 1 MG, QOD,. During the same period patient was treated with PREDNISONE. Patient recovered.

Prograf Side Effects Report #4590335-4
Prograf side effect was reported by a Physician from on Feb 07, 2005. Male patient, 52 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Prograf. After drug was administered, patient experienced the following side effects: bone marrow depression, graft versus host disease, multi-organ failure, oral candidiasis, stem cell transplant, systemic candida. Prograf dosage: unknown. During the same period patient was treated with MYCOPHENOLATE MOFETIL, PREDNISONE. Patient died.

Prograf Side Effects Report #4681531-6
Prograf side effect was reported by a Physician from on May 17, 2005. Male patient, 51 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Prograf. After drug was administered, patient experienced the following side effects: graft versus host disease, myopathy toxic, necrosis. Prograf dosage: unknown. During the same period patient was treated with HYDROXYCHLOROQUINE SULPHATE, MYCOPHENOLATE MOFETIL, PREDNISONE. Patient recovered.

Prograf Side Effects Report #5117672-9
Prograf side effect was reported by a Physician from UNITED STATES on Sept 13, 2006. Male patient, 38 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Prograf. After drug was administered, patient experienced the following side effects: gastrointestinal haemorrhage, graft versus host disease, hypotension, pancreas infection, pancytopenia. Prograf dosage: unknown. During the same period patient was treated with MYCOPHENOLATE MOFETIL, PREDNISONE. Patient died.


Prograf Side Effects Report #5117667-5
Prograf side effect was reported by a Physician from UNITED STATES on Sept 13, 2006. Female patient, 27 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Prograf. After drug was administered, patient experienced the following side effects: graft versus host disease, kidney transplant rejection, leukopenia, multi-organ failure. Prograf dosage: unknown. During the same period patient was treated with MYCOPHENOLATE MOFETIL, PREDNISOLONE ACETATE. Patient died.

Prograf Side Effects Report #4635940-1
Prograf side effect was reported by a Physician from on Apr 06, 2005. Male patient, 17 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Prograf. After drug was administered, patient experienced the following side effects: cerebral toxoplasmosis, graft versus host disease, toxic induced encephalopathy. Prograf dosage: unknown. During the same period patient was treated with PREDNISONE. Patient died.

Prograf Side Effects Report #5535044-X
Prograf side effect was reported by a Physician from UNITED STATES on Nov 15, 2007. Male patient, 55 years of age, was diagnosed with prophylaxis against graft versus host disease and was treated with Prograf. After drug was administered, patient experienced the following side effects: acute graft versus host disease in intestine, acute graft versus host disease in liver, acute graft versus host disease in skin, condition aggravated, encephalopathy, haemolytic anaemia, headache , influenza like illness. Prograf dosage: 1 MG, UID/QD. Patient recovered.

Prograf Side Effects Report #5472536-6
Prograf side effect was reported by a Physician from JAPAN on Sept 13, 2007. Female patient, 45 years of age, was diagnosed with myasthenia gravis and was treated with Prograf. After drug was administered, patient experienced the following side effects: cough, erythrodermic psoriasis, graft versus host disease, staphylococcal infection . Prograf dosage: 4 MG, D, ORAL. During the same period patient was treated with PREDNISOLONE. Patient was hospitalized. Patient recovered.

Prograf Side Effects Report #5409827-0
Prograf side effect was reported by a Physician from JAPAN on July 25, 2007. Female patient, 41 years of age, was diagnosed with myasthenia gravis and was treated with Prograf. After drug was administered, patient experienced the following side effects: graft versus host disease, malignant neoplasm progression, metastasis, respiratory failure, thymoma, thymoma malignant recurrent. Prograf dosage: 3 MG, UID/QD, ORAL. During the same period patient was treated with MYTELASE, PREDNISOLONE, ATROPINE SULPHATE, GASTERLET, SELBEX, BIOFERMIN. Patient died on 12/29/2005.


Prograf Side Effects Report #5419995-2
Prograf side effect was reported by a Physician from JAPAN on Aug 02, 2007. Female patient, 41 years of age, was diagnosed with myasthenia gravis and was treated with Prograf. After drug was administered, patient experienced the following side effects: graft versus host disease, malignant neoplasm progression, metastases to abdominal cavity, metastasis, respiratory failure, thymoma malignant recurrent. Prograf dosage: 3 MG, UID/QD, ORAL. During the same period patient was treated with MYTELASE, PREDNISOLONE, ATROPINE SULPHATE, GASTERLET, SELBEX, BIOFERMIN. Patient died on 12/29/2005.

Prograf Side Effects Report #6081486-6
Prograf side effect was reported by a Health Professional from CANADA on Feb 05, 2009. Female patient, 35 years of age, was diagnosed with lung transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: aplastic anaemia, bone marrow failure, convulsion, diarrhoea, graft versus host disease, hepatosplenic candidiasis, infection , nausea . Prograf dosage: unknown. During the same period patient was treated with AZATHIOPRINE, VALGANCICLOVIR, TRIMETHOPRIM. Patient died.

Prograf Side Effects Report #5129055-6
Prograf side effect was reported by a Physician from UNITED STATES on Sept 29, 2006. Female patient, 66 years of age, was diagnosed with liver transplant rejection and was treated with Prograf. After drug was administered, patient experienced the following side effects: ascites, cytomegalovirus colitis, enterococcal sepsis, graft versus host disease, malaise, multi-organ failure. Prograf dosage: unknown. During the same period patient was treated with MYCOPHENOLATE MOFETIL, PREDNISONE, METHYLPREDNISOLONE, SIMULECT. Patient died.

Prograf Side Effects Report #5421839-X
Prograf side effect was reported by a Physician from UNITED STATES on July 18, 2007. Male patient, 58 years of age, was diagnosed with liver transplant rejection and was treated with Prograf. After drug was administered, patient experienced the following side effects: bile duct stenosis, graft versus host disease, liver transplant rejection, post procedural bile leak. Prograf dosage: unknown. During the same period patient was treated with MYCOPHENOLATE MOFETIL, PREDNISOLONE, HYDROCORTISONE. Patient recovered.

Prograf Side Effects Report #5515363-3
Prograf side effect was reported by a Physician from UNITED STATES on Nov 02, 2007. Female patient, 55 years of age, was diagnosed with liver transplant rejection and was treated with Prograf. After drug was administered, patient experienced the following side effects: graft versus host disease, infection , pleural effusion. Prograf dosage: 2 MG, BID, ORAL. During the same period patient was treated with MYCOPHENOLATE MOFETIL, BACTRIM, ACTIGALL, BUMEX, PEPCID, FLEXERIL, NORCO. Patient was hospitalized. Patient died on 06/05/2007.


Prograf Side Effects Report #4750350-4
Prograf side effect was reported by a Physician from JAPAN on Aug 05, 2005. Female patient, 61 years of age, weighting 84.88 lb, was diagnosed with liver transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: abdominal distension, cytomegalovirus infection , dehydration, diarrhoea, graft versus host disease, inflammation, lumbar vertebral fracture, pneumatosis intestinalis, pneumocystis jiroveci pneumonia. Prograf dosage: 3.00 MG, BID, ORAL. During the same period patient was treated with PREDNISOLONE, CELLCEPT, OMEPRAZOLE, URSODIOL, COTRIM, DIFLUCAN, MAALOX, SUCRALFATE. Patient was hospitalized. Patient recovered.

Prograf Side Effects Report #5647581-8
Prograf side effect was reported by a Physician from UNITED STATES on Feb 21, 2008. Female patient, 55 years of age, was diagnosed with liver transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: anastomotic stenosis, bone marrow failure, enterococcal sepsis, graft versus host disease, influenza like illness, multi-organ failure, pancytopenia. Prograf dosage: 2 MG,BID, ORAL. During the same period patient was treated with MYCOPHENOLATE MOFETIL, SULFAMETHOXAZOLE AND TRIMETHOPRIM, ACTIGALL, BUMEX, PEPCID, FLEXERIL, NORCO. Patient died on 06/05/2007.

Prograf Side Effects Report #5218646-X
Prograf side effect was reported by a Physician from CHINA on Jan 09, 2007. Female patient, 54 years of age, was diagnosed with liver transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: anaemia, blood culture positive, cytomegalovirus infection , epidermal necrosis, gastric ulcer, graft versus host disease, large intestinal ulcer, multi-organ disorder. Prograf dosage: unknown. During the same period patient was treated with MYCOPHENOLATE MOFETIL, METHYLPREDNISOLONE. Patient died.

Prograf Side Effects Report #5291330-2
Prograf side effect was reported by a Physician from CHINA on Mar 13, 2007. Female patient, 54 years of age, was diagnosed with liver transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: abdominal pain , cytomegalovirus infection , diarrhoea, graft versus host disease, multi-organ failure, staphylococcal infection . Prograf dosage: unknown. During the same period patient was treated with MYCOPHENOLATE MOFETIL, METHYLPREDNISOLONE, CYCLOSPORINE, MORPHINE, PIPERACILLIN. Patient died.

Prograf Side Effects Report #5713728-8
Prograf side effect was reported by a Physician from JAPAN on Apr 04, 2008. Male patient, child 4 years of age, was diagnosed with liver transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: autoimmune disorder, epstein-barr virus infection, graft versus host disease, idiopathic thrombocytopenic purpura, lymphoproliferative disorder, post procedural complication, varicella. Prograf dosage: unknown. During the same period patient was treated with PREDNISOLONE. Patient recovered.

Prograf Side Effects Report #4600825-3
Prograf side effect was reported by a Physician from on Feb 18, 2005. Female patient, child 3. years of age, was diagnosed with liver transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, adenovirus infection, cystitis haemorrhagic, diarrhoea, graft versus host disease, multi-organ failure, nephritis, pneumonia , sepsis . Prograf dosage: unknown. During the same period patient was treated with PREDNISONE, MYCOPHENOLATE MOFETIL, METHOTREXATE, BASILIXIMAB. Patient was hospitalized. Patient died.

Prograf Side Effects Report #5054123-7
Prograf side effect was reported by a Health Professional from FRANCE on July 04, 2006. Male patient was diagnosed with liver transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: bacterial infection , graft versus host disease, hyperthermia, multi-organ failure, nikolsky's sign, pathogen resistance, staphylococcal infection , toxic epidermal necrolysis. Prograf dosage: unknown. During the same period patient was treated with CELLCEPT. Patient died on 06/07/2006.

Prograf Side Effects Report #5313515-9
Prograf side effect was reported by a Consumer or non-health professional from GERMANY on Apr 09, 2007. Female patient, child 12 years of age, was diagnosed with graft versus host disease and was treated with Prograf. After drug was administered, patient experienced the following side effects: chapped lips, erythema, graft versus host disease, pain , swelling. Prograf dosage: unknown. Patient died.

Prograf Side Effects Report #4961653-2
Prograf side effect was reported by a Physician from JAPAN on Mar 16, 2006. Male patient, 61 years of age, was diagnosed with bone marrow transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: encephalitis , graft versus host disease, human herpesvirus 6 infection, thrombotic microangiopathy. Prograf dosage: unknown. During the same period patient was treated with METHOTREXATE. Patient recovered.

Prograf Side Effects Report #5011367-8
Prograf side effect was reported by a Physician from JAPAN on May 10, 2006. Female patient, 61 years of age, weighting 98.33 lb, was diagnosed with bone marrow transplant , graft versus host disease and was treated with Prograf. After drug was administered, patient experienced the following side effects: cerebral haemorrhage, encephalitis herpes, graft versus host disease, liver disorder, renal failure acute, thrombotic microangiopathy, venoocclusive liver disease. Prograf dosage: unknown. During the same period patient was treated with PREDNISOLONE, PREDONINE, METHOTREXATE, ALLOPURINOL. Patient died on 10/12/2004.


Prograf Side Effects Report #5015897-4
Prograf side effect was reported by a Physician from JAPAN on May 10, 2006. Male patient, 61 years of age, weighting 94.80 lb, was diagnosed with bone marrow transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: complications of bone marrow transplant, cystitis haemorrhagic, encephalitis herpes, graft versus host disease, human herpes virus 6 serology positive, pancytopenia, pneumonia , renal failure acute. Prograf dosage: unknown. During the same period patient was treated with PREDNISOLONE, METHOTREXATE, DIFLUCAN. Patient died on 03/08/2003.

Prograf Side Effects Report #5030143-3
Prograf side effect was reported by a Physician from JAPAN on June 02, 2006. Female patient, 61 years of age, weighting 98.33 lb, was diagnosed with bone marrow transplant , graft versus host disease and was treated with Prograf. After drug was administered, patient experienced the following side effects: cerebral haemorrhage, depressed level of consciousness, diarrhoea, disorientation, encephalitis herpes, graft versus host disease, liver disorder, memory impairment. Prograf dosage: unknown. During the same period patient was treated with PREDNISOLONE, PREDONINE, METHOTREXATE, ALLOPURINOL. Patient died on 10/12/2004.

Prograf Side Effects Report #4961776-8
Prograf side effect was reported by a Physician from JAPAN on Mar 16, 2006. Female patient, 60 years of age, was diagnosed with bone marrow transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: encephalitis herpes, graft versus host disease, thrombotic microangiopathy, venoocclusive liver disease. Prograf dosage: unknown. During the same period patient was treated with METHOTREXATE. Patient died on 01/01/2004.

Prograf Side Effects Report #4801347-7
Prograf side effect was reported by a Physician from JAPAN on Sept 27, 2005. Male patient, child 6 years of age, weighting 61.73 lb, was diagnosed with bone marrow transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: blood culture positive, diarrhoea, graft versus host disease, neutrophil count decreased, pyrexia, rash , white blood cell count decreased, wound infection staphylococcal. Prograf dosage: unknown. During the same period patient was treated with METHOTREXATE. Patient died on 01/01/2004.

Prograf Side Effects Report #4941567-4
Prograf side effect was reported by a Physician from JAPAN on Feb 27, 2006. Male patient, 59 years of age, was diagnosed with bone marrow transplant , fungal infection  and was treated with Prograf. After drug was administered, patient experienced the following side effects: blood beta-d-glucan increased, engraftment syndrome, graft versus host disease, haemoptysis, mucormycosis, thrombotic microangiopathy. Prograf dosage: unknown. During the same period patient was treated with FUNGUARD, CYCLOSPORINE, METHYLPREDNISOLONE, ITRACONAZOLE. Patient died on 09/01/2005.

Prograf Side Effects Report #4961650-7
Prograf side effect was reported by a Physician from JAPAN on Mar 15, 2006. Male patient, 59 years of age, was diagnosed with bone marrow transplant , fungal infection  and was treated with Prograf. After drug was administered, patient experienced the following side effects: blood beta-d-glucan increased, candidiasis, graft versus host disease, haemoptysis, mucormycosis, thrombotic microangiopathy. Prograf dosage: unknown. During the same period patient was treated with FUNGUARD, CYCLOSPORINE, METHYLPREDNISOLONE, ITRACONAZOLE. Patient died on 09/01/2005.

Prograf Side Effects Report #4962817-4
Prograf side effect was reported by a Physician from JAPAN on Mar 15, 2006. Male patient, 59 years of age, was diagnosed with bone marrow transplant , fungal infection  and was treated with Prograf. After drug was administered, patient experienced the following side effects: blood beta-d-glucan increased, candida sepsis, graft versus host disease, haemoptysis, mucormycosis, thrombotic microangiopathy. Prograf dosage: unknown. During the same period patient was treated with FUNGUARD, CYCLOSPORINE, METHYLPREDNISOLONE. Patient died on 09/01/2005.

Prograf Side Effects Report #5383236-5
Prograf side effect was reported by a Physician from JAPAN on June 22, 2007. Male patient, 58 years of age, weighting 147.7 lb, was diagnosed with bone marrow transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: coma hepatic, complications of transplant surgery, dialysis , graft versus host disease, hepatitis fulminant, pyrexia, renal impairment, tremor. Prograf dosage: unknown. During the same period patient was treated with PREDNISOLONE, MUCOSTA, LAC B, DEPAS, DIFLUCAN. Patient died on 10/24/2004.

Prograf Side Effects Report #5705347-4
Prograf side effect was reported by a Physician from JAPAN on Mar 25, 2008. Male patient, 58 years of age, weighting 147.7 lb, was diagnosed with bone marrow transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: altered state of consciousness, asterixis, dialysis , graft versus host disease, hepatic failure, hepatitis fulminant, pyrexia, renal impairment. Prograf dosage: ORAL; 0.5 MG, BID, ORAL. During the same period patient was treated with PREDNISOLONE, MUCOSTA, LAC B, DEPAS, DIFLUCAN. Patient died on 10/24/2004.

Prograf Side Effects Report #4551206-2
Prograf side effect was reported by a Physician from on Dec 22, 2004. Male patient, 57 years of age, was diagnosed with bone marrow transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: anorectal disorder, bladder disorder, cellulitis staphylococcal, diaphragmatic paralysis, extradural abscess, graft versus host disease, headache , monoplegia, multi-organ failure. Prograf dosage: unknown. During the same period patient was treated with METHOTREXATE, FLUDARABINE PHOSPHATE, BUSULFAN. Patient died.


Prograf Side Effects Report #4565818-3
Prograf side effect was reported by a Physician from on Jan 19, 2005. Male patient, 57 years of age, was diagnosed with bone marrow transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: anorectal disorder, bladder disorder, cellulitis staphylococcal, condition aggravated, diaphragmatic paralysis, extradural abscess, gastrointestinal disorder, graft versus host disease, headache . Prograf dosage: unknown. During the same period patient was treated with METHOTREXATE, FLUDARABINE PHOSPHATE, BISULFAN. Patient died on 07/19/2004.

Prograf Side Effects Report #4589651-1
Prograf side effect was reported by a Physician from on Jan 19, 2005. Male patient, 57 years of age, was diagnosed with bone marrow transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: anorectal disorder, bladder disorder, cellulitis staphylococcal, extradural abscess, graft versus host disease, headache , monoplegia, multi-organ failure, neck pain. Prograf dosage: unknown. During the same period patient was treated with METHOTREXATE, FLUDARABINE PHOSPHATE, BUSULFAN. Patient died on 07/19/2004.

Prograf Side Effects Report #4951200-3
Prograf side effect was reported by a Physician from JAPAN on Mar 01, 2006. Male patient, 57 years of age, was diagnosed with bone marrow transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: cerebral haemorrhage, complications of transplant surgery, diarrhoea, graft versus host disease, hepatic function abnormal, histiocytosis haematophagic, pneumonia staphylococcal, pyrexia. Prograf dosage: unknown. During the same period patient was treated with METHOTREXATE, FLUDARABINE PHOSPHATE, BUSULFAN, ANTITHYMOCYTE IMMUNOGLOBULIN, METHYPREDNSIOLONE. Patient died.

Prograf Side Effects Report #4954520-1
Prograf side effect was reported by a Physician from JAPAN on Mar 10, 2006. Male patient, 57 years of age, was diagnosed with bone marrow transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: cerebral haemorrhage, diarrhoea, graft versus host disease, hepatic function abnormal, histiocytosis haematophagic, pneumonia staphylococcal, serum ferritin increased. Prograf dosage: unknown. During the same period patient was treated with METHOTREXATE, FLUDARABINE PHOSPHATE, BUSULFAN, ANTITHYMOCYTE IMMUNOGLOBULIN, METHYLPREDNISOLONE. Patient died.

Prograf Side Effects Report #4707056-7
Prograf side effect was reported by a Physician from JAPAN on June 17, 2005. Male patient, 56 years of age, was diagnosed with bone marrow transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: adenoviral haemorrhagic cystitis, cytomegalovirus infection , erythema, graft versus host disease, renal impairment, thrombotic microangiopathy. Prograf dosage: unknown. During the same period patient was treated with METHYLPREDNISOLONE, MYCOPHENOLATE MOFETIL. Patient was hospitalized. Patient recovered.

Prograf Side Effects Report #4905375-2
Prograf side effect was reported by a Physician from JAPAN on Jan 26, 2006. Male patient, 56 years of age, was diagnosed with bone marrow transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: graft versus host disease, sepsis . Prograf dosage: 0.03 MG/KG, IV NOS. During the same period patient was treated with METHYLPREDNISOLONE. Patient died.

Prograf Side Effects Report #4906566-7
Prograf side effect was reported by a Physician from JAPAN on Jan 26, 2006. Male patient, 56 years of age, was diagnosed with bone marrow transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: graft versus host disease, sepsis . Prograf dosage: 0.03 MG/KG, IV NOS. During the same period patient was treated with METHYLPREDNISOLONE. Patient died.

Prograf Side Effects Report #4912001-5
Prograf side effect was reported by a Physician from JAPAN on Feb 02, 2006. Male patient, 56 years of age, was diagnosed with bone marrow transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: graft versus host disease, sepsis . Prograf dosage: 0.03 MG/KG, D, IV NOS. During the same period patient was treated with METHYLPREDNISOLONE. Patient died.

Prograf Side Effects Report #4900783-8
Prograf side effect was reported by a Physician from JAPAN on Jan 19, 2006. Female patient, 55 years of age, was diagnosed with bone marrow transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: bone marrow failure, encephalitis herpes, engraftment syndrome, graft versus host disease, herpes zoster, nausea , stem cell transplant. Prograf dosage: unknown. Patient recovered.

Prograf Side Effects Report #5015900-1
Prograf side effect was reported by a Physician from JAPAN on May 18, 2006. Female patient, 55 years of age, weighting 94.80 lb, was diagnosed with bone marrow transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: cytomegalovirus infection , encephalopathy, febrile neutropenia, graft versus host disease, hydrocephalus , thrombotic microangiopathy. Prograf dosage: 0.7 MG, CONTINUOUS, IV DRIP. During the same period patient was treated with GASTER D, ZOVIRAX, SOL MEDROL, MEROPEN, VANCOMYCIN, NEUTROGIN, METHOTREXATE, DIFLUCAN. Patient died on 04/21/2005.


Prograf Side Effects Report #4983255-4
Prograf side effect was reported by a Physician from JAPAN on Apr 07, 2006. Male patient, 54 years of age, was diagnosed with bone marrow transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: graft versus host disease. Prograf dosage: unknown. Patient died on 06/01/2004.

Prograf Side Effects Report #4564360-3
Prograf side effect was reported by a Physician from on Jan 12, 2005. Female patient, 53 years of age, weighting 127.9 lb, was diagnosed with bone marrow transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: brain oedema, condition aggravated, convulsion, encephalopathy, enterocolitis, graft versus host disease, nervous system disorder, pathogen resistance, pneumonia . Prograf dosage: 0.6 MG, UID/QD, INTRAVENOUS; 1.2 MG, 0.8, 0.7 MG, UID/QD. During the same period patient was treated with MEROPEN, NEUTROGIN, VANCOMYCIN. Patient recovered.

Prograf Side Effects Report #5160825-4
Prograf side effect was reported by a Physician from JAPAN on Nov 07, 2006. Male patient, 51 years of age, was diagnosed with bone marrow transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: biopsy colon abnormal, complications of bone marrow transplant, cytomegalovirus infection , diarrhoea, graft versus host disease, hepatic function abnormal. Prograf dosage: unknown. During the same period patient was treated with CYCLOSPORINE, PREDNISOLONE. Patient died.

Prograf Side Effects Report #4686866-9
Prograf side effect was reported by a Physician from on May 30, 2005. Female patient, 51 years of age, was diagnosed with bone marrow transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: bone marrow depression, coma, convulsion, encephalitis herpes, graft versus host disease, haemorrhagic diathesis, nephropathy toxic, sepsis , thrombocytopenia. Prograf dosage: unknown. During the same period patient was treated with THIOTEPA, CYCLOPHOSPHAMIDE, METHOTREXATE, ACYCLOVIR, POLYVALENT IMMUNOGLOBULIN, FLUDARABINE PHOSPHATE, LYMPHOGLOBULINE, PREDNISOLONE. Patient was hospitalized. Patient recovered.

Prograf Side Effects Report #4690155-6
Prograf side effect was reported by a Physician from on June 03, 2005. Female patient, 51 years of age, was diagnosed with bone marrow transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: bone marrow depression, coma, convulsion, encephalitis herpes, graft complication, graft versus host disease, haemorrhagic diathesis, nephropathy toxic, sepsis . Prograf dosage: unknown. During the same period patient was treated with THIOTEPA, METHOTREXATE, ACYCLOVIR, POLYVALENT IMMUNOGLOBULIN, FLUDARABINE PHOSPHATE, LYMPHOGLOBULINE, PREDNISONE. Patient was hospitalized. Patient recovered.

Prograf Side Effects Report #4690164-7
Prograf side effect was reported by a Physician from on June 03, 2005. Female patient, 51 years of age, was diagnosed with bone marrow transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: adenovirus infection, cytomegalovirus antigen positive, depressed level of consciousness, epstein-barr virus infection, graft versus host disease, hepatitis fulminant, steroid withdrawal syndrome. Prograf dosage: unknown. During the same period patient was treated with CORTICOSTEROIDS, GANCICLOVIR, CYCLOSPORINE. Patient died on 01/01/2004.

Prograf Side Effects Report #4709346-0
Prograf side effect was reported by a Physician from JAPAN on June 23, 2005. Female patient, 51 years of age, weighting 143.3 lb, was diagnosed with bone marrow transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: abdominal pain , adenoviral hepatitis, blood pressure decreased, coagulopathy, condition aggravated, depressed level of consciousness, epstein-barr virus test positive, graft versus host disease, haemodialysis. Prograf dosage: 0.80 MG, BID, ORAL. During the same period patient was treated with PREDNISOLONE, DENOSINE, DIFLUCAN, BAKTAR, GRAN, FUNGUARD, ZOVIRAX, ITRIZOLE. Patient died on 09/07/2004.

Prograf Side Effects Report #4830945-X
Prograf side effect was reported by a Consumer or non-health professional from JAPAN on Oct 28, 2005. Female patient, 51 years of age, was diagnosed with bone marrow transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: bone marrow failure, bone marrow transplant , coma, convulsion, encephalitis herpes, encephalopathy, graft versus host disease, haemorrhagic diathesis, hyperreflexia. Prograf dosage: unknown. During the same period patient was treated with THIOTEPA, CYCLOPHOSPHAMIDE, METHOTREXATE, ACYCLOVIR, POLYVALENT IMMUNOGLOBULIN), FLUDARABINE PHOSPHATE, LYMPHOGLOBULINE, PREDNISONE. Patient was hospitalized. Patient recovered.

Prograf Side Effects Report #4941579-0
Prograf side effect was reported by a Physician from JAPAN on Feb 27, 2006. Male patient, 51 years of age, was diagnosed with bone marrow transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: asthenia, cellulitis , cerebral infarction, cytomegalovirus viraemia, depressed level of consciousness, graft versus host disease, headache , mucormycosis. Prograf dosage: unknown. During the same period patient was treated with METHOTREXATEMULATION, METHYLPREDNISOLONE. Patient died on 02/01/2005.

Prograf Side Effects Report #4961651-9
Prograf side effect was reported by a Physician from JAPAN on Mar 16, 2006. Male patient, 51 years of age, was diagnosed with bone marrow transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: asthenia, cellulitis , cerebral infarction, cytomegalovirus viraemia, graft versus host disease, headache , mucormycosis. Prograf dosage: unknown. During the same period patient was treated with METHOTREXATE, METHYLPREDNISOLONE. Patient died on 02/01/2005.


Prograf Side Effects Report #5777982-9
Prograf side effect was reported by a Physician from UNITED STATES on June 03, 2008. Female patient, 49 years of age, was diagnosed with bone marrow transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: bronchopulmonary aspergillosis, diarrhoea, disease progression, graft versus host disease, hypotension, malignant pleural effusion, multiple myeloma , musculoskeletal disorder, plasmacytoma. Prograf dosage: 1 MG, BID. Patient was hospitalized. Patient died on 04/24/2007.

Prograf Side Effects Report #4961638-6
Prograf side effect was reported by a Physician from JAPAN on Mar 16, 2006. Male patient, 47 years of age, was diagnosed with bone marrow transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: cerebral haemorrhage, convulsion, encephalitis herpes, encephalopathy, graft versus host disease, thrombotic microangiopathy, venoocclusive liver disease. Prograf dosage: unknown. During the same period patient was treated with METHOTREXATE. Patient died on 08/22/2001.

Prograf Side Effects Report #5016319-X
Prograf side effect was reported by a Physician from JAPAN on May 10, 2006. Male patient, 47 years of age, weighting 147.7 lb, was diagnosed with bone marrow transplant , graft versus host disease and was treated with Prograf. After drug was administered, patient experienced the following side effects: complications of bone marrow transplant, convulsion, diarrhoea, encephalitis herpes, graft versus host disease, haemodialysis, human herpesvirus 6 infection, melaena. Prograf dosage: unknown. Patient died on 08/22/2001.

Prograf Side Effects Report #5038771-6
Prograf side effect was reported by a Physician from JAPAN on June 02, 2006. Male patient, 47 years of age, weighting 147.7 lb, was diagnosed with bone marrow transplant , graft versus host disease and was treated with Prograf. After drug was administered, patient experienced the following side effects: bone marrow transplant , complications of transplant surgery, convulsion, diarrhoea, encephalitis herpes, encephalopathy, graft versus host disease, melaena. Prograf dosage: unknown. Patient died on 08/22/2001.

Prograf Side Effects Report #4952412-5
Prograf side effect was reported by a Physician from JAPAN on Mar 07, 2006. Male patient, 46 years of age, weighting 143.3 lb, was diagnosed with bone marrow transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: graft versus host disease, pneumonia cytomegaloviral, pseudomonal sepsis. Prograf dosage: 0.75 MG UID/QD IV NOS. During the same period patient was treated with METHOTREXATE, CELLCEPT, METHYLPREDNISLONE, CYCLOPHOSPHAMIDE, DENOSIDE, PREDNISOLONE. Patient died on 04/17/2002.

Prograf Side Effects Report #4964983-3
Prograf side effect was reported by a Physician from JAPAN on Mar 17, 2006. Male patient, 46 years of age, weighting 143.3 lb, was diagnosed with bone marrow transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: graft versus host disease, pneumonia cytomegaloviral, pseudomonal sepsis. Prograf dosage: 0.75 MG, UID/QD, IV NOS. During the same period patient was treated with METHOTREXATE, CELLCEPT, METHYLPREDNISOLONE, CYCLOPHOSPHAMIDE, DENOSINE TANABE. Patient died on 04/17/2002.

Prograf Side Effects Report #4559083-0
Prograf side effect was reported by a Physician from on Jan 07, 2005. Male patient, 44 years of age, was diagnosed with bone marrow transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: graft versus host disease. Prograf dosage: unknown. During the same period patient was treated with MYCOPHENOLATE MOFETIL, ANTITHYMOCYTE IMMUNOGLOBULIN, CORTICOSTEROIDS, DACLIZUMAB, ETANERCEPT. Patient died.

Prograf Side Effects Report #4690165-9
Prograf side effect was reported by a Physician from on June 08, 2005. Female patient, 44 years of age, was diagnosed with bone marrow transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: cardio-respiratory arrest, coma, convulsion, disorientation, encephalitis herpes, encephalitis viral, graft versus host disease, leukoencephalopathy. Prograf dosage: unknown. During the same period patient was treated with THIOTEPA, CYCLOPHOSPHAMIDE, ACYCLOVIR. Patient died.

Prograf Side Effects Report #4830959-X
Prograf side effect was reported by a Physician from JAPAN on Oct 28, 2005. Female patient, 44 years of age, was diagnosed with bone marrow transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: cardio-respiratory arrest, coma, convulsion, disorientation, encephalitis herpes, graft versus host disease, leukoencephalopathy. Prograf dosage: unknown. During the same period patient was treated with THIOTEPA, CYCLOPHOSPHAMIDE, ACYCLOVIR. Patient died.

Prograf Side Effects Report #4994139-X
Prograf side effect was reported by a Physician from JAPAN on Apr 26, 2006. Male patient, 43 years of age, was diagnosed with bone marrow transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: encephalopathy, graft versus host disease, pneumonia cytomegaloviral, respiratory failure. Prograf dosage: 2 MG, UID/QD, IV NOS; SEE IMAGE. During the same period patient was treated with METHOTREXATE, CYCLOPHOSPHAMIDE, NEUPOGEN, TIENAM, DECADRON. Patient died on 10/09/2005.

Prograf Side Effects Report #5030520-0
Prograf side effect was reported by a Physician from JAPAN on June 05, 2006. Male patient, 43 years of age, was diagnosed with bone marrow transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: depressed level of consciousness, graft versus host disease, pneumonia cytomegaloviral, respiratory failure, toxic induced encephalopathy. Prograf dosage: 2 MG, CONTINUOUS, IV DRIP; SEE IMAGE. During the same period patient was treated with METHOTREXATE, ENDOXAN, NEUPOGEN, TIENAM, DECADRON. Patient died on 10/09/2005.

Prograf Side Effects Report #4961774-4
Prograf side effect was reported by a Physician from JAPAN on Mar 16, 2006. Female patient, 42 years of age, was diagnosed with bone marrow transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: complications of transplant surgery, encephalitis , graft versus host disease, thrombotic microangiopathy, venoocclusive liver disease. Prograf dosage: unknown. During the same period patient was treated with METHOTREXATE. Patient died on 01/01/2002.

Prograf Side Effects Report #5015898-6
Prograf side effect was reported by a Physician from JAPAN on May 10, 2006. Female patient, 42 years of age, weighting 112.4 lb, was diagnosed with bone marrow transplant , graft versus host disease and was treated with Prograf. After drug was administered, patient experienced the following side effects: depressed level of consciousness, encephalitis herpes, graft versus host disease, hepatic failure, thrombotic microangiopathy, venoocclusive liver disease. Prograf dosage: unknown. During the same period patient was treated with CYCLOSPORINE, METHOTREXATE. Patient died on 06/18/2002.

Prograf Side Effects Report #5030527-3
Prograf side effect was reported by a Physician from JAPAN on June 02, 2006. Female patient, 42 years of age, weighting 112.4 lb, was diagnosed with bone marrow transplant , graft versus host disease and was treated with Prograf. After drug was administered, patient experienced the following side effects: condition aggravated, encephalitis herpes, graft versus host disease, haemodialysis, hepatic failure, metastases to liver, thrombotic microangiopathy, venoocclusive liver disease. Prograf dosage: 0.5 MG, CONTINUOUS, IV NOS; SEE IMAGE. During the same period patient was treated with CYCLOSPORINE. Patient died on 06/18/2002.

Prograf Side Effects Report #5207353-5
Prograf side effect was reported by a Physician from JAPAN on Dec 27, 2006. Female patient, 41 years of age, weighting 170.9 lb, was diagnosed with bone marrow transplant , fungal infection  and was treated with Prograf. After drug was administered, patient experienced the following side effects: encephalitis herpes, engraftment syndrome, graft versus host disease, hepatic enzyme increased, thrombotic microangiopathy. Prograf dosage: unknown. During the same period patient was treated with FUNGUARD. Patient recovered.

Prograf Side Effects Report #5165833-5
Prograf side effect was reported by a Physician from JAPAN on Nov 13, 2006. Female patient, 41 years of age, weighting 170.9 lb, was diagnosed with bone marrow transplant , fungal infection  and was treated with Prograf. After drug was administered, patient experienced the following side effects: blood creatinine increased, encephalitis herpes, engraftment syndrome, graft versus host disease, hepatic enzyme increased, infection , plasminogen activator inhibitor increased, thrombocytopenia, thrombotic microangiopathy. Prograf dosage: unknown. During the same period patient was treated with FUNGUARD, VANCOMYCIN. Patient recovered.

Prograf Side Effects Report #5193194-4
Prograf side effect was reported by a Physician from JAPAN on Dec 08, 2006. Female patient, 41 years of age, weighting 170.9 lb, was diagnosed with bone marrow transplant , fungal infection  and was treated with Prograf. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, encephalitis herpes, engraftment syndrome, graft versus host disease, hepatic enzyme increased, thrombocytopenia, thrombotic microangiopathy. Prograf dosage: 0.5 MG, SEE IMAGE. During the same period patient was treated with FUNGUARD. Patient recovered.

Prograf Side Effects Report #5477633-7
Prograf side effect was reported by a Physician from JAPAN on Sept 20, 2007. Male patient, 41 years of age, was diagnosed with bone marrow transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: graft versus host disease, non-hodgkin's lymphoma recurrent, thrombotic microangiopathy. Prograf dosage: 0.03 MG/LG, /D. During the same period patient was treated with METHOTREXATE, PREDNISONE, MYCOPHENOLATE MOFETIL. Patient recovered.

Prograf Side Effects Report #5613361-2
Prograf side effect was reported by a Physician from JAPAN on Jan 10, 2008. Male patient, 41 years of age, was diagnosed with bone marrow transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: angiopathy, complications of bone marrow transplant, graft versus host disease. Prograf dosage: unknown. During the same period patient was treated with METHOTREXATE, METHYLPREDNISOLONE. Patient died.

Prograf Side Effects Report #4846914-X
Prograf side effect was reported by a Physician from JAPAN on Nov 21, 2005. Male patient, child 4 years of age, was diagnosed with bone marrow transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: atrioventricular block, convulsion, graft versus host disease, hypertension, myocarditis, reversible posterior leukoencephalopathy syndrome. Prograf dosage: unknown. During the same period patient was treated with METHOTREXATE. Patient recovered.

Prograf Side Effects Report #4852984-5
Prograf side effect was reported by a Physician from JAPAN on Nov 29, 2005. Male patient, child 4 years of age, was diagnosed with bone marrow transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: atrioventricular block complete, graft versus host disease, hypertension, myocarditis, reversible posterior leukoencephalopathy syndrome. Prograf dosage: unknown. During the same period patient was treated with CYCLOSPORINE, METHOTREXATE. Patient recovered.