Protamine and no therapeutic response Patient Reports February 10, 2010

Protamine Side Effects Report #5534532-X
Protamine side effect was reported by a Pharmacist from UNITED STATES on Dec 04, 2007. Male patient, 74 years of age, was diagnosed with coronary artery bypass  and was treated with Protamine. After drug was administered, patient experienced the following side effects: haemodynamic instability, no therapeutic response, post procedural haemorrhage. Protamine dosage: 450MG ONCE IV. During the same period patient was treated with PROTAMINE SULPHATE, HEPARIN, APROTINEN, STANDARD OPERATIVE PROTOCOL ANESTHETICS, CEPHALOSPORIN, CARDIPLEGIA SOLUTIONS. Patient recovered.

Protamine Side Effects Report #4588332-8
Protamine side effect was reported by a Pharmacist from on Feb 15, 2005. Male patient, 58 years of age, weighting 120.3 lb, was treated with Protamine. After drug was administered, patient experienced the following side effects: cardiac output decreased, hypotension, no therapeutic response, prolonged expiration, pulmonary arterial pressure abnormal, pulmonary arterial wedge pressure decreased, vasodilatation, ventricular dysfunction. Protamine dosage: unknown. During the same period patient was treated with SIMVASTATIN, ASPIRIN, DIPYRIDAMOLE, FOLIC ACID, LISINOPRIL, ZANTAC, ATENOLOL, LASIX. Patient recovered.

Protamine Side Effects Report #5796327-1
Protamine side effect was reported by a Physician from UNITED STATES on June 30, 2008. Male patient, weighting 143.3 lb, was treated with Protamine. After drug was administered, patient experienced the following side effects: blood pressure systolic decreased, hypotension, no therapeutic response, procedural complication, vasodilatation. Protamine dosage: unknown. Patient recovered.