Sevorane and alanine aminotransferase increased Patient Reports February 10, 2010

Sevorane Side Effects Report #5703594-9
Sevorane side effect was reported by a Health Professional from FRANCE on Apr 03, 2008. Female patient, 38 years of age, weighting 158.7 lb, was diagnosed with anaesthesia, pruritus and was treated with Sevorane. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood alkaline phosphatase increased, cholecystitis chronic, cytolytic hepatitis, gamma-glutamyltransferase increased, jaundice , jaundice cholestatic. Sevorane dosage: unknown. During the same period patient was treated with DESFLURANE, CEFAZOLIN, URSODESOXYCHOLIC ACID. Patient was hospitalized. Patient recovered.

Sevorane Side Effects Report #5705520-5
Sevorane side effect was reported by a Health Professional from FRANCE on Apr 07, 2008. Female patient, 38 years of age, weighting 158.7 lb, was diagnosed with anaesthesia, pruritus and was treated with Sevorane. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood alkaline phosphatase increased, cholecystitis chronic, cytolytic hepatitis, gamma-glutamyltransferase increased, jaundice , jaundice cholestatic. Sevorane dosage: unknown. During the same period patient was treated with DESFLURANE, CEFAZOLIN, URSODESOXYCHOLIC ACID. Patient was hospitalized. Patient recovered.

Sevorane Side Effects Report #5213566-9
Sevorane side effect was reported by a Health Professional from FRANCE on Jan 11, 2007. Female patient, weighting 4.96 lb, was diagnosed with anaesthesia, induction of anaesthesia, maintenance of anaesthesia and was treated with Sevorane. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, blood creatine phosphokinase increased, coagulation factor decreased, cytolytic hepatitis, disseminated intravascular coagulation, haematemesis, hepatic failure, hyperglycaemia, liver disorder. Sevorane dosage: unknown. During the same period patient was treated with SEVORANE LIQUID INHALATION, DESFLURANE, PROPOFOL, SUFENTANIL CITRATE, SUFENTANIL CITRATE, HYDROXYETHYLAMIDON, ALFENTANIL. Patient recovered.

Sevorane Side Effects Report #5342758-3
Sevorane side effect was reported by a Health Professional from FRANCE on May 24, 2007. Female patient, weighting 149.9 lb, was diagnosed with anaesthesia and was treated with Sevorane. After drug was administered, patient experienced the following side effects: abdominal pain upper, alanine aminotransferase increased, aspartate aminotransferase increased, blood lactate dehydrogenase increased, cytolytic hepatitis, gamma-glutamyltransferase increased, vomiting. Sevorane dosage: unknown. During the same period patient was treated with ISOFLURANE, PARACETAMOL, PANTOPRAZOLE, NEFOPAM, HYDROXYZINE HYDROCHLORIDE, PROPOFOL. Patient was hospitalized. Patient recovered.


Sevorane Side Effects Report #5374033-5
Sevorane side effect was reported by a Health Professional from GERMANY on June 18, 2007. Female patient, weighting 149.9 lb, was diagnosed with anaesthesia and was treated with Sevorane. After drug was administered, patient experienced the following side effects: abdominal pain upper, alanine aminotransferase increased, aspartate aminotransferase increased, blood lactate dehydrogenase increased, cytolytic hepatitis, gamma-glutamyltransferase increased, vomiting. Sevorane dosage: unknown. During the same period patient was treated with FORENE LIQUID INHALATION, PARACETAMOL, INIPOMP, NEFOPAM HYDROCHLORIDE, HYDROXYZINE. Patient was hospitalized. Patient recovered.

Sevorane Side Effects Report #5195439-3
Sevorane side effect was reported by a Health Professional from FRANCE on Dec 22, 2006. Female patient, weighting 4.96 lb, was diagnosed with anaesthesia, induction of anaesthesia, maintenance of anaesthesia and was treated with Sevorane. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, blood creatine phosphokinase increased, coagulation factor decreased, cytolytic hepatitis, disseminated intravascular coagulation, haematemesis, hepatic failure, hyperglycaemia, liver disorder. Sevorane dosage: unknown. During the same period patient was treated with SEVORANE LIQUID INHALATION, DESFLURANE, PROPOFOL, SUFENTANIL CITRATE, SUFENTANIL CITRATE, HYDROXYETHYLAMIDON, ALFENTANIL. Patient recovered.

Sevorane Side Effects Report #5359647-0
Sevorane side effect was reported by a Health Professional from FRANCE on June 06, 2007. Male patient, 70 years of age, was treated with Sevorane. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, cytolytic hepatitis, prothrombin level abnormal. Sevorane dosage: unknown. During the same period patient was treated with PARACETAMOL, ATRACURIUM BESYLATE, PROPOFOL, FENTANYL, CEFAZOLIN, AMLODIPINE, FENOFIBRATE, TAMSULOSINE. Patient was hospitalized. Patient recovered.

Sevorane Side Effects Report #5374026-8
Sevorane side effect was reported by a Health Professional from FRANCE on June 21, 2007. Male patient, 70 years of age, was treated with Sevorane. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, cytolytic hepatitis, prothrombin level decreased. Sevorane dosage: unknown. During the same period patient was treated with PARACETAMOL, ATRACURIUM BESYLATE, PROPOFOL, FENTANYL, CEFAZOLIN, AMLODIPINE, FENOFIBRATE, TAMSULOSINE. Patient was hospitalized. Patient recovered.