Sevorane and hepatic failure Patient Reports February 10, 2010

Sevorane Side Effects Report #5227700-8
Sevorane side effect was reported by a Health Professional from FRANCE on Jan 25, 2007. Male patient, 57 years of age, was diagnosed with anaesthesia and was treated with Sevorane. After drug was administered, patient experienced the following side effects: ascites, blood bilirubin decreased, condition aggravated, escherichia infection, gastroenteritis escherichia coli, gastrointestinal disorder, hepatic encephalopathy, hepatic failure, hepatitis cholestatic. Sevorane dosage: unknown. During the same period patient was treated with PROPOFOL, TIANEPTINE, OXAZEPAM, FOLIC ACID, MEPROBARNATC, OMEPRAZOLE. Patient was hospitalized. Patient recovered.

Sevorane Side Effects Report #5238754-7
Sevorane side effect was reported by a Health Professional from FRANCE on Feb 05, 2007. Male patient, 57 years of age, was diagnosed with anaesthesia and was treated with Sevorane. After drug was administered, patient experienced the following side effects: ascites, condition aggravated, escherichia infection, gastrointestinal disorder, hepatic failure, hepatitis cholestatic, jaundice , mycoplasma infection, oedema. Sevorane dosage: unknown. During the same period patient was treated with PROPOFOL, TIANEPTINE, OXAZEPAM, FOLIC ACID, MEPROBARNATC, OMEPRAZOLE. Patient was hospitalized. Patient recovered.

Sevorane Side Effects Report #5258189-0
Sevorane side effect was reported by a Health Professional from FRANCE on Feb 26, 2007. Male patient, 57 years of age, was diagnosed with anaesthesia and was treated with Sevorane. After drug was administered, patient experienced the following side effects: ascites, condition aggravated, escherichia infection, gastrointestinal disorder, hepatic failure, hepatitis cholestatic, jaundice , mycoplasma infection, oedema. Sevorane dosage: unknown. During the same period patient was treated with PROPOFOL, TIANEPTINE, OXAZEPAM, FOLIC ACID, MEPROBARNATC, OMEPRAZOLE. Patient was hospitalized. Patient recovered.

Sevorane Side Effects Report #4869987-7
Sevorane side effect was reported by a Consumer or non-health professional from FRANCE on Dec 07, 2005. Female patient, 53 years of age, was diagnosed with anaesthesia and was treated with Sevorane. After drug was administered, patient experienced the following side effects: cholestasis, hepatic failure, hepatitis , liver function test abnormal. Sevorane dosage: unknown. During the same period patient was treated with ALFENTANIL, PROPOFOL. Patient was hospitalized. Patient recovered.


Sevorane Side Effects Report #5213566-9
Sevorane side effect was reported by a Health Professional from FRANCE on Jan 11, 2007. Female patient, weighting 4.96 lb, was diagnosed with anaesthesia, induction of anaesthesia, maintenance of anaesthesia and was treated with Sevorane. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, blood creatine phosphokinase increased, coagulation factor decreased, cytolytic hepatitis, disseminated intravascular coagulation, haematemesis, hepatic failure, hyperglycaemia, liver disorder. Sevorane dosage: unknown. During the same period patient was treated with SEVORANE LIQUID INHALATION, DESFLURANE, PROPOFOL, SUFENTANIL CITRATE, SUFENTANIL CITRATE, HYDROXYETHYLAMIDON, ALFENTANIL. Patient recovered.

Sevorane Side Effects Report #5195439-3
Sevorane side effect was reported by a Health Professional from FRANCE on Dec 22, 2006. Female patient, weighting 4.96 lb, was diagnosed with anaesthesia, induction of anaesthesia, maintenance of anaesthesia and was treated with Sevorane. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, blood creatine phosphokinase increased, coagulation factor decreased, cytolytic hepatitis, disseminated intravascular coagulation, haematemesis, hepatic failure, hyperglycaemia, liver disorder. Sevorane dosage: unknown. During the same period patient was treated with SEVORANE LIQUID INHALATION, DESFLURANE, PROPOFOL, SUFENTANIL CITRATE, SUFENTANIL CITRATE, HYDROXYETHYLAMIDON, ALFENTANIL. Patient recovered.