Sevorane and muscle rigidity Patient Reports February 10, 2010

Sevorane Side Effects Report #5310425-8
Sevorane side effect was reported by a Physician from ROMANIA on Apr 17, 2007. Male patient, 14 years of age, weighting 132.3 lb, was diagnosed with maintenance of anaesthesia, hypotonia and was treated with Sevorane. After drug was administered, patient experienced the following side effects: acidosis, cardio-respiratory arrest, hyperthermia, muscle rigidity. Sevorane dosage: unknown. During the same period patient was treated with ROCURONIUM BROMIDE, ROCURONIUM BROMIDE, ROCURONIUM BROMIDE, FENTANYL, MIDAZOLAM, PROPOFOL. Patient died on 04/16/2007.

Sevorane Side Effects Report #5322833-X
Sevorane side effect was reported by a Physician from ROMANIA on May 03, 2007. Male patient, 14 years of age, weighting 132.3 lb, was diagnosed with maintenance of anaesthesia, hypotonia and was treated with Sevorane. After drug was administered, patient experienced the following side effects: acidosis, brain oedema, cardio-respiratory arrest, cardiopulmonary failure, hyperthermia, muscle rigidity, pulmonary oedema. Sevorane dosage: unknown. During the same period patient was treated with ROCURONIUM BROMIDE, ROCURONIUM BROMIDE, ROCURONIUM BROMIDE, FENTANYL, MIDAZOLAM, PROPOFOL. Patient died on 04/16/2007.

Sevorane Side Effects Report #5163070-1
Sevorane side effect was reported by a Physician from CHILE on Nov 23, 2006. Male patient, child 4 years of age, weighting 41.89 lb, was diagnosed with induction of anaesthesia and was treated with Sevorane. After drug was administered, patient experienced the following side effects: hyperthermia, muscle rigidity. Sevorane dosage: unknown. Patient was hospitalized. Patient recovered.

Sevorane Side Effects Report #5600745-1
Sevorane side effect was reported by a Physician from ISRAEL on Jan 15, 2008. Male patient, child 2 years of age, weighting 22.05 lb, was diagnosed with induction of anaesthesia, maintenance of anaesthesia and was treated with Sevorane. After drug was administered, patient experienced the following side effects: agitation, muscle rigidity. Sevorane dosage: unknown. During the same period patient was treated with FENTANYL, MORPHINE. Patient recovered.


Sevorane Side Effects Report #5215435-7
Sevorane side effect was reported by a Physician from CHILE on Jan 12, 2007. Male patient, weighting 41.89 lb, was diagnosed with induction of anaesthesia and was treated with Sevorane. After drug was administered, patient experienced the following side effects: hyperthermia, muscle rigidity. Sevorane dosage: unknown. Patient was hospitalized. Patient recovered.

Sevorane Side Effects Report #5425765-1
Sevorane side effect was reported by a Physician from SWITZERLAND on Aug 16, 2007. Female patient, 28 years of age, was diagnosed with gastrooesophageal reflux disease and was treated with Sevorane. After drug was administered, patient experienced the following side effects: body temperature increased, hyperhidrosis, hyperthermia malignant, malaise, muscle rigidity, muscle spasms, tachycardia. Sevorane dosage: unknown. During the same period patient was treated with SUCCINYLCHOLINE CHLORIDE, PROPOFOL, FENTANYL, VENLAFAXINE, QUETIAPINE FUMARATE, ZOLPIDEM TARTRATE, ESOMEPRAZOLE MAGNESIUM, MACROGOL. Patient recovered.

Sevorane Side Effects Report #5445610-8
Sevorane side effect was reported by a Physician from SWITZERLAND on Aug 27, 2007. Female patient, 28 years of age, was diagnosed with gastrooesophageal reflux disease and was treated with Sevorane. After drug was administered, patient experienced the following side effects: body temperature increased, hyperhidrosis, hyperthermia malignant, malaise, muscle rigidity, muscle spasms, tachycardia. Sevorane dosage: unknown. During the same period patient was treated with SUCCINYLCHOLINE CHLORIDE, PROPOFOL, FENTANYL, VENLAFAXINE, QUETIAPINE FUMARATE, ZOLPIDEM TARTRATE, ESOMEPRAZOLE MAGNESIUM, MACROGOL. Patient recovered.