Sintrom and blood lactate dehydrogenase increased Patient Reports February 09, 2010

Sintrom Side Effects Report #4843512-9
Sintrom side effect was reported by a Consumer or non-health professional from UNITED STATES on Aug 23, 2004. Male patient, 36 years of age, was diagnosed with pulmonary embolism , convulsion, oligodendroglioma, pain , prophylaxis against gastrointestinal ulcer, thrombosis prophylaxis and was treated with Sintrom. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood lactate dehydrogenase increased, gamma-glutamyltransferase increased, hepatocellular damage, international normalised ratio decreased. Sintrom dosage: 5 TO 6 MG/DAY. During the same period patient was treated with TEGRETOL, TEMODAL, CELEBREX, NEXIUM, FRAXIPARINE, TRAMAL. Patient recovered.

Sintrom Side Effects Report #4843705-0
Sintrom side effect was reported by a Consumer or non-health professional from FRANCE on Nov 23, 2005. Female patient, 62 years of age, was treated with Sintrom. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, ammonia increased, aspartate aminotransferase increased, blood albumin decreased, blood lactate dehydrogenase increased, cutaneous vasculitis, gamma-glutamyltransferase increased, hepatic encephalopathy. Sintrom dosage: 2 MG/DAY. During the same period patient was treated with LOPRESSOR, PREVISCAN, CAPTOPRIL, LASILIX, DELURSAN, NPH INSULIN, LANTUS, ACTRAPID INSULIN NOVO. Patient was hospitalized. Patient recovered.