Soliris and ammonia increased Patient Reports February 09, 2010

Soliris Side Effects Report #5331759-7
Soliris side effect was reported by a Physician from UNITED STATES on Apr 30, 2007. Male patient, 80 years of age, weighting 190.9 lb, was diagnosed with paroxysmal nocturnal haemoglobinuria, infection prophylaxis, pneumocystis jiroveci pneumonia and was treated with Soliris. After drug was administered, patient experienced the following side effects: ammonia increased, confusional state, dermatitis bullous, haemorrhage, headache , impaired healing, lichenoid keratosis, mental status changes. Soliris dosage: 600 MG, SINGLE, INTRAVENOUS. During the same period patient was treated with BACTRIM, PREDNISONE. Patient was hospitalized. Patient recovered.

Soliris Side Effects Report #5355326-4
Soliris side effect was reported by a Physician from UNITED STATES on May 24, 2007. Male patient, 80 years of age, weighting 190.9 lb, was diagnosed with paroxysmal nocturnal haemoglobinuria, antifungal prophylaxis, pneumonia  and was treated with Soliris. After drug was administered, patient experienced the following side effects: ammonia increased, confusional state, dermatitis bullous, haemorrhage, headache , lichenoid keratosis, neutropenia, renal failure acute. Soliris dosage: 600 MG, SINGLE, INTRAVENOUS. During the same period patient was treated with BACTRIM, PREDNISONE. Patient was hospitalized. Patient recovered.