Targretin and disease progression Patient Reports February 10, 2010

Targretin Side Effects Report #5689665-4
Targretin side effect was reported by a Physician from SPAIN on Feb 25, 2008. Female patient, 51 years of age, was diagnosed with mycosis fungoides and was treated with Targretin. After drug was administered, patient experienced the following side effects: disease progression, mycosis fungoides. Targretin dosage: 450 MG, ORAL. During the same period patient was treated with PREDNISOLONE, INTERFERON ALFA. Patient was hospitalized. Patient recovered.

Targretin Side Effects Report #4806858-6
Targretin side effect was reported by a Consumer or non-health professional from SPAIN on Oct 04, 2005. Female patient, 48 years of age, was diagnosed with mycosis fungoides and was treated with Targretin. After drug was administered, patient experienced the following side effects: dermatitis exfoliative, disease progression, leukocytosis, mycosis fungoides. Targretin dosage: 225 MG QD PO. During the same period patient was treated with DARBEPOETIN ALFA, LEVOFLOXACIN. Patient was hospitalized. Patient died on 08/01/2005.

Targretin Side Effects Report #5676707-5
Targretin side effect was reported by a Physician from UNITED STATES on Feb 09, 2007. Male patient, 63 years of age, weighting 189.6 lb, was diagnosed with lymphoma , mycosis fungoides and was treated with Targretin. After drug was administered, patient experienced the following side effects: disease progression. Targretin dosage: 150 MG, QD, ORAL. Patient recovered.

Targretin Side Effects Report #4918232-2
Targretin side effect was reported by a Physician from UNITED STATES on Jan 30, 2006. Male patient, 74 years of age, was diagnosed with acute myeloid leukaemia and was treated with Targretin. After drug was administered, patient experienced the following side effects: atrial fibrillation , cough, disease progression, haemoglobin decreased, platelet count decreased, retinoic acid syndrome. Targretin dosage: 300 MG QD PO. Patient was hospitalized. Patient recovered.