Topotecan and confusional state Patient Reports March 16, 2010



Topotecan Side Effects Report #5256466-0
Topotecan side effect was reported by a Physician from UNITED STATES on Mar 01, 2007. Male patient, 53 years of age, weighting 238.5 lb, was diagnosed with small cell lung cancer metastatic and was treated with Topotecan. After drug was administered, patient experienced the following side effects: confusional state, disorientation, fatigue, mental status changes. Topotecan dosage: 3MGM2 CYCLIC. During the same period patient was treated with BORTEZOMIB. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5922025-7
Topotecan side effect was reported by a Physician from UNITED STATES on Oct 15, 2008. Male patient, 77 years of age, weighting 182.3 lb, was diagnosed with small cell lung cancer extensive stage, asthma What is  asthma and was treated with Topotecan. After drug was administered, patient experienced the following side effects: confusional state, dyspnoea, neutropenia, pyrexia. Topotecan dosage: 4MGM2 CYCLIC. During the same period patient was treated with CARBOPLATIN, FEXOFENADINE, THEOPHYLLINE, AZELASTINE, ALBUTEROL, FLUTICASONE. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5950199-0
Topotecan side effect was reported by a Physician from UNITED STATES on Nov 06, 2008. Male patient, 77 years of age, weighting 182.3 lb, was diagnosed with small cell lung cancer extensive stage, asthma What is  asthma and was treated with Topotecan. After drug was administered, patient experienced the following side effects: confusional state, dyspnoea, neutropenia, pyrexia. Topotecan dosage: 4MGM2 CYCLIC. During the same period patient was treated with CARBOPLATIN, FEXOFENADINE, THEOPHYLLINE, AZELASTINE, ALBUTEROL, FLUTICASONE. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #4976753-0
Topotecan side effect was reported by a Physician from CANADA on Aug 25, 2005. Female patient, 54 years of age, was diagnosed with non-small cell lung cancer and was treated with Topotecan. After drug was administered, patient experienced the following side effects: cardiovascular disorder, confusional state, depressed level of consciousness, dyspnoea, muscle twitching, oedema peripheral, pyrexia. Topotecan dosage: unknown. During the same period patient was treated with TAXOTERE. Patient was hospitalized. Patient died on 09/07/2005.


Topotecan Side Effects Report #4988533-0
Topotecan side effect was reported by a Physician from CANADA on Aug 25, 2005. Female patient, 54 years of age, was diagnosed with non-small cell lung cancer and was treated with Topotecan. After drug was administered, patient experienced the following side effects: cardiovascular disorder, confusional state, depressed level of consciousness, dyspnoea, muscle twitching, oedema peripheral, pneumonia What is  pneumonia, pyrexia. Topotecan dosage: 3.5MGM2 CYCLIC. During the same period patient was treated with TAXOTERE. Patient was hospitalized. Patient died on 09/07/2005.

Topotecan Side Effects Report #5067808-3
Topotecan side effect was reported by a Physician from ITALY on July 28, 2006. Female patient, 50 years of age, was diagnosed with neoplasm malignant and was treated with Topotecan. After drug was administered, patient experienced the following side effects: anaemia, confusional state, neutropenia, thrombocytopenia. Topotecan dosage: unknown. During the same period patient was treated with HYCAMTIN, CARBOPLATIN, FOLIC ACID, OMEPRAZOLE, THYROXINE. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5593292-7
Topotecan side effect was reported by a Physician from CANADA on Jan 07, 2008. Male patient, 59 years of age, weighting 253.3 lb, was diagnosed with metastases to central nervous system and was treated with Topotecan. After drug was administered, patient experienced the following side effects: confusional state, headache What is  headache, lethargy. Topotecan dosage: 1MG CYCLIC. During the same period patient was treated with RADIATION. Patient was hospitalized. Patient died on 12/16/2007.

Topotecan Side Effects Report #5072620-5
Topotecan side effect was reported by a Physician from UNITED STATES on July 28, 2006. Female patient, 81 years of age, weighting 152.1 lb, was diagnosed with malignant melanoma and was treated with Topotecan. After drug was administered, patient experienced the following side effects: confusional state, hyponatraemia, lethargy. Topotecan dosage: 2.5MGM2 CYCLIC. During the same period patient was treated with TEMOZOLOMIDE. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5082398-7
Topotecan side effect was reported by a Physician from UNITED STATES on July 28, 2006. Female patient, 81 years of age, weighting 152.1 lb, was diagnosed with malignant melanoma and was treated with Topotecan. After drug was administered, patient experienced the following side effects: confusional state, hyponatraemia, lethargy. Topotecan dosage: 2.5MGM2 CYCLIC. During the same period patient was treated with TEMOZOLOMIDE. Patient was hospitalized. Patient recovered.


Topotecan Side Effects Report #5063852-0
Topotecan side effect was reported by a Health Professional from UNITED STATES on July 26, 2006. Female patient, weighting 334.7 lb, was diagnosed with malignant melanoma and was treated with Topotecan. After drug was administered, patient experienced the following side effects: confusional state, hyponatraemia, lethargy. Topotecan dosage: (2.5 MG/M2) D1, 8, 15 OF 28 IV. During the same period patient was treated with TEMOZOLOMIDE, IBUPROFEN, PERCOCET, DARVOCET, ACETAMINOPHEN, VOLTAREN, COMPAZINE, FOSAMAX. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5293523-7
Topotecan side effect was reported by a Physician from DENMARK on Apr 04, 2007. Female patient, 72 years of age, was treated with Topotecan. After drug was administered, patient experienced the following side effects: anorexia, blood potassium decreased, blood pressure decreased, body temperature increased, confusional state, dehydration, dizziness What is  dizziness, dysphagia, fatigue. Topotecan dosage: 3.2MG PER DAY. During the same period patient was treated with CISPLATIN. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5316893-X
Topotecan side effect was reported by a Physician from DENMARK on Apr 29, 2007. Female patient, 72 years of age, was treated with Topotecan. After drug was administered, patient experienced the following side effects: anorexia, blood pressure decreased, body temperature increased, confusional state, dehydration, dizziness What is  dizziness, dysphagia, fatigue, fungal infection What is  fungal infection. Topotecan dosage: 3.2MG PER DAY. During the same period patient was treated with CISPLATIN, MAGNESIUM SULPHATE, METOCLOPRAMIDE, METHYLPREDNISOLONE SUCCINATE, POTASSIUM ACETATE. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5330001-0
Topotecan side effect was reported by a Physician from DENMARK on May 14, 2007. Female patient, 72 years of age, was treated with Topotecan. After drug was administered, patient experienced the following side effects: anorexia, blood pressure decreased, body temperature increased, confusional state, dehydration, dizziness What is  dizziness, dysphagia, fatigue, fungal infection What is  fungal infection. Topotecan dosage: 3.2MG PER DAY. During the same period patient was treated with CISPLATIN, MAGNESIUM SULPHATE, METOCLOPRAMIDE, METHYLPREDNISOLONE SUCCINATE, POTASSIUM ACETATE. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5373532-X
Topotecan side effect was reported by a Physician from DENMARK on June 18, 2007. Female patient, 72 years of age, was treated with Topotecan. After drug was administered, patient experienced the following side effects: anorexia, blood creatinine increased, blood potassium decreased, blood pressure decreased, body temperature increased, confusional state, dehydration, dizziness What is  dizziness, dysphagia. Topotecan dosage: 3.2MG PER DAY. During the same period patient was treated with CISPLATIN, MAGNESIUM SULPHATE, METOCLOPRAMIDE, METHYLPREDNISOLONE SUCCINATE, POTASSIUM ACETATE. Patient was hospitalized. Patient recovered.


Topotecan Side Effects Report #6128309-4
Topotecan side effect was reported by a Physician from UNITED STATES on Mar 20, 2009. Female patient, 69 years of age, weighting 213.4 lb, was treated with Topotecan. After drug was administered, patient experienced the following side effects: accidental overdose, anaemia, asthenia, condition aggravated, confusional state, fall What is  fall, leukopenia, lung cancer metastatic, sepsis What is  sepsis. Topotecan dosage: 2.3MGM2 PER DAY. During the same period patient was treated with RADIATION, STEROID. Patient was hospitalized. Patient died on 03/08/2009.

Topotecan Side Effects Report #4626345-8
Topotecan side effect was reported by a Physician from on Apr 01, 2005. Male patient, 63 years of age, weighting 211.9 lb, was diagnosed with hypertension, pain What is  pain, nausea What is  nausea and was treated with Topotecan. After drug was administered, patient experienced the following side effects: cardiac arrest What is  cardiac arrest, confusional state, electromechanical dissociation, hepatotoxicity, hyperkalaemia, liver function test abnormal, oedema peripheral, renal failure, renal failure acute. Topotecan dosage: 4MGM2 WEEKLY. During the same period patient was treated with LOTREL, HYDROCODONE, HYDROCHLOROTHIAZIDE, VIOXX, COMPAZINE, TRANSFUSION. Patient was hospitalized. Patient died on 07/12/2004.

Topotecan Side Effects Report #5574936-2
Topotecan side effect was reported by a Physician from CANADA on Dec 21, 2007. Male patient, 59 years of age, weighting 253.3 lb, was treated with Topotecan. After drug was administered, patient experienced the following side effects: confusional state, headache What is  headache, lethargy. Topotecan dosage: 1MG CYCLIC. Patient was hospitalized. Patient died on 12/16/2007.

Topotecan Side Effects Report #5908676-4
Topotecan side effect was reported by a Physician from CANADA on Sept 26, 2008. Male patient, 59 years of age, weighting 253.3 lb, was treated with Topotecan. After drug was administered, patient experienced the following side effects: confusional state, disease progression, headache What is  headache, hydrocephalus What is  hydrocephalus, lethargy. Topotecan dosage: 1.1MGM2 PER DAY. During the same period patient was treated with RADIATION. Patient was hospitalized. Patient died on 12/16/2007.

Topotecan Side Effects Report #5115271-6
Topotecan side effect was reported by a Consumer or non-health professional from UNITED STATES on Sept 21, 2006. Male patient, 58 years of age, was treated with Topotecan. After drug was administered, patient experienced the following side effects: abdominal distension, cardiac arrest What is  cardiac arrest, confusional state, grand mal convulsion, ileus, lethargy, sepsis What is  sepsis, sinus bradycardia, somnolence. Topotecan dosage: 1MGM2 CYCLIC. During the same period patient was treated with TIPIFARNIB, LOVENOX, OXYCONTIN, PERCOCET, SELENIUM SULFIDE, VITAMIN E, ENZYMES. Patient was hospitalized. Patient died on 09/28/2000.


Topotecan Side Effects Report #4730174-4
Topotecan side effect was reported by a Physician from UNITED STATES on July 22, 2005. Female patient, 49 years of age, weighting 136.2 lb, was treated with Topotecan. After drug was administered, patient experienced the following side effects: abdominal pain What is  abdominal pain, cardiac arrest What is  cardiac arrest, confusional state, intestinal obstruction, pleural effusion, respiratory failure. Topotecan dosage: .75MGM2 CYCLIC. During the same period patient was treated with CISPLATIN. Patient was hospitalized. Patient died on 03/27/2002.

Topotecan Side Effects Report #5256262-4
Topotecan side effect was reported by a Health Professional from UNITED STATES on Mar 02, 2007. Male patient, weighting 238.0 lb, was treated with Topotecan. After drug was administered, patient experienced the following side effects: confusional state, disorientation, fatigue, mental status changes. Topotecan dosage: 3 MG/M2 D 1,8,15 Q28 IV. Patient recovered.
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side effects of Topotecan