Trastuzumab and disease progression Patient Reports February 09, 2010

Trastuzumab Side Effects Report #5546341-6
Trastuzumab side effect was reported by a Physician from UNITED KINGDOM on Nov 26, 2007. Female patient, weighting 154.3 lb, was diagnosed with breast cancer metastatic and was treated with Trastuzumab. After drug was administered, patient experienced the following side effects: disease progression, intracranial tumour haemorrhage, polyneuropathy. Trastuzumab dosage: 150 MG, UNK. During the same period patient was treated with PACLITAXEL, BONDRONAT, TAMOXIFEN CITRATE, ZOLADEX, CISPLATIN, CYCLOPHOSPHAMIDE, EPIRUBICIN, ETOPOSIDE. Patient was hospitalized. Patient died on 11/06/2007.

Trastuzumab Side Effects Report #5751445-9
Trastuzumab side effect was reported by a Physician from UNITED KINGDOM on May 07, 2008. Female patient, weighting 189.6 lb, was diagnosed with breast cancer metastatic, diabetes mellitus and was treated with Trastuzumab. After drug was administered, patient experienced the following side effects: abdominal pain , anorexia, asthenia, bone marrow toxicity, chromaturia, disease progression, febrile neutropenia, gastritis. Trastuzumab dosage: 172 MG, UNK. During the same period patient was treated with DOCETAXEL, BENDAMUSTINE, DEXAMETHASONE, CAELYX, AROMASIN. Patient was hospitalized. Patient recovered.

Trastuzumab Side Effects Report #5449127-6
Trastuzumab side effect was reported by a Physician from UNITED KINGDOM on Aug 29, 2007. Female patient was diagnosed with breast cancer metastatic and was treated with Trastuzumab. After drug was administered, patient experienced the following side effects: disease progression, ejection fraction decreased. Trastuzumab dosage: 2 MG/KG, 1/WEEK. During the same period patient was treated with LAPATINIB. Patient died on 01/19/2007.

Trastuzumab Side Effects Report #5531823-3
Trastuzumab side effect was reported by a Physician from UNITED KINGDOM on Nov 23, 2007. Female patient, weighting 154.3 lb, was treated with Trastuzumab. After drug was administered, patient experienced the following side effects: disease progression, intracranial tumour haemorrhage. Trastuzumab dosage: 150 MG, UNK. During the same period patient was treated with PACLITAXEL, BONDRONAT. Patient was hospitalized. Patient died on 11/06/2007.