Trisenox and alanine aminotransferase increased Patient Reports February 10, 2010

Trisenox Side Effects Report #4855373-2
Trisenox side effect was reported by a Health Professional from UNITED STATES on May 31, 2005. Male patient, 79 years of age, was diagnosed with myelodysplastic syndrome and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood alkaline phosphatase increased. Trisenox dosage: 19 MG (0.25 MG/KG, 5 DOSE LOAD), IVI. During the same period patient was treated with CHLOROQUINE PHOSPHATE, DEMADEX, OXYCODONE, DESYREL, ARANESP, MEPROBAMATE, POTASSIUM, ALLOPURINOL. Patient recovered.

Trisenox Side Effects Report #4855372-0
Trisenox side effect was reported by a Health Professional from UNITED STATES on Apr 05, 2005. Male patient, 70 years of age, weighting 175.0 lb, was diagnosed with myelodysplastic syndrome and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, av dissociation, fatigue, oedema peripheral, platelet count decreased, pyrexia, rash

. Trisenox dosage: unknown. Patient was hospitalized. Patient recovered.

Trisenox Side Effects Report #4735806-2
Trisenox side effect was reported by a Physician from UNITED STATES on July 18, 2005. Male patient, weighting 191.8 lb, was diagnosed with myelodysplastic syndrome and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, blood alkaline phosphatase increased, blood glucose increased, diarrhoea. Trisenox dosage: 15 MG (15 MG, BIW), IVI. During the same period patient was treated with ASCORBIC ACID. Patient recovered.

Trisenox Side Effects Report #5642185-5
Trisenox side effect was reported by a Health Professional from UNITED STATES on Feb 12, 2008. Female patient, 17 years of age, weighting 169.8 lb, was diagnosed with b-cell lymphoma and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood potassium increased, blood uric acid increased, cardiac arrest

, constipation

, depressed level of consciousness, disease progression. Trisenox dosage: DAYS 1-5 X 4 WKS Q6WKS; UNIT DOSE: .2 MG/KG; 0.20 MG/KG; ROUTE; INTRAVENOUS DRIP. During the same period patient was treated with ALBUTEROL, GRANISETRON, ACYCLOVIR, RANITIDINE, MORPHINE, DIPHENHYDRAMINE, SULFAMETHOXAZOLE AND TRIMETHOPRIM, BISACODYL. Patient was hospitalized. Patient died on 01/29/2004.

Trisenox Side Effects Report #5536194-4
Trisenox side effect was reported by a Physician from JAPAN on Nov 20, 2007. Male patient, 88 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood albumin decreased, blood alkaline phosphatase increased, c-reactive protein increased, electrocardiogram qt prolonged, fluid retention, gamma-glutamyltransferase increased, hepatic function abnormal. Trisenox dosage: 7.05 MG QD INTRAVENOUS DRIP. During the same period patient was treated with SULFAMETHOXAZOLE AND TRIMETHOPRIM, POLYMYXIN B SULPHATE. Patient recovered.

Trisenox Side Effects Report #5768221-3
Trisenox side effect was reported by a Physician from JAPAN on May 26, 2008. Male patient, 85 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, diarrhoea, electrocardiogram qt prolonged, hepatic function abnormal, hyperglycaemia, leukocytosis, pleural effusion, pneumonia

. Trisenox dosage: 8.4 MG DAILY INTRAVENOUS. During the same period patient was treated with GABAXATE MESILATE. Patient recovered.

Trisenox Side Effects Report #6073095-X
Trisenox side effect was reported by a Physician from JAPAN on Jan 28, 2009. Male patient, 85 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: acute promyelocytic leukaemia differentiation syndrome, alanine aminotransferase increased, blood lactate dehydrogenase increased, diarrhoea, electrocardiogram qt prolonged, gamma-glutamyltransferase increased, hyperglycaemia, leukocytosis, leukopenia. Trisenox dosage: 8.4 MG DAILY INTRAVENOUS. During the same period patient was treated with GABEXATE MESILATE. Patient recovered.

Trisenox Side Effects Report #5768567-9
Trisenox side effect was reported by a Health Professional from CANADA on May 28, 2008. Female patient, 84 years of age, was diagnosed with acute promyelocytic leukaemia, haematological malignancy, upper respiratory tract infection and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, arrhythmia

, aspartate aminotransferase increased, atrial fibrillation

, blood lactic acid increased, blood potassium increased, cardiotoxicity, electrocardiogram qt prolonged, electrocardiogram st segment elevation. Trisenox dosage: 14 MG ONCE INTRAVENOUS DRIP. During the same period patient was treated with CIPRO, ATENOLOL, LORAZEPAM, DOCUSATE, FUROSEMIDE, POTASSIUM CHLORIDE, MAGNESIUM OXIDE. Patient died.

Trisenox Side Effects Report #5964847-2
Trisenox side effect was reported by a Physician from JAPAN on Nov 07, 2008. Male patient, 84 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, altered state of consciousness, anorexia, aphasia

, aspartate aminotransferase increased, asterixis, cerebellar infarction, disorientation, dizziness

. Trisenox dosage: 6.6 MG/DAY INTRAVENOUS DRIP. Patient recovered.

Trisenox Side Effects Report #5975236-9
Trisenox side effect was reported by a Physician from JAPAN on Nov 14, 2008. Male patient, 84 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, altered state of consciousness, anorexia, aphasia

, aspartate aminotransferase increased, asterixis, blood creatinine increased, blood potassium decreased, blood urea increased. Trisenox dosage: 6.6 MG QD INTRAVENOUS DRIP. Patient recovered.

Trisenox Side Effects Report #5608248-5
Trisenox side effect was reported by a Physician from JAPAN on Jan 11, 2008. Male patient, 80 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, electrocardiogram qt prolonged, enterocolitis, hepatic function abnormal, pancytopenia, renal impairment. Trisenox dosage: unknown. Patient was hospitalized. Patient recovered.

Trisenox Side Effects Report #5671610-9
Trisenox side effect was reported by a Physician from JAPAN on Feb 29, 2008. Male patient, 80 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, electrocardiogram qt prolonged, enterocolitis, hepatic function abnormal, pancytopenia, renal impairment. Trisenox dosage: 8.25 MG QD INTRAVENOUS DRIP. During the same period patient was treated with DISOPYRAMIDE PHOSPHATE, MEXILETINE HYDROCHLORIDE. Patient was hospitalized. Patient recovered.

Trisenox Side Effects Report #5270157-1
Trisenox side effect was reported by a Physician from JAPAN on Feb 28, 2007. Male patient, 79 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, electrocardiogram qt prolonged, facial palsy, hepatic function abnormal, herpes zoster, liver disorder, rash

. Trisenox dosage: 8.0625MG. During the same period patient was treated with DISOPYRAMIDE PHOSPHATE, MEXILETINE HYDROCHLORIDE, NIFEDIPINE, HALOXAZOLAM, ZOLPIDEM TARTRATE. Patient was hospitalized and became disabled. Patient recovered.

Trisenox Side Effects Report #5320873-8
Trisenox side effect was reported by a Physician from JAPAN on Apr 23, 2007. Male patient, 79 years of age, was diagnosed with acute promyelocytic leukaemia, arrhythmia

and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, electrocardiogram qt prolonged, facial palsy, febrile neutropenia, herpes zoster, liver disorder, rash

. Trisenox dosage: 8.0625 MG DAILY. During the same period patient was treated with DISOPYRAMIDE PHOSPHATE, MEXILETINE HYDROCHLORIDE, NIFEDIPINE, HALOXAZOLAM, ZOLPIDEM TARTRATE. Patient was hospitalized and became disabled. Patient recovered.

Trisenox Side Effects Report #5309186-8
Trisenox side effect was reported by a Physician from JAPAN on Apr 09, 2007. Female patient, 77 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood albumin decreased, blood lactate dehydrogenase increased, electrocardiogram qt prolonged, fibrin d dimer increased, gamma-glutamyltransferase increased, protein total decreased, white blood cell count decreased. Trisenox dosage: 9.315 MG QD INTRAVENOUS DRIP. During the same period patient was treated with FAMOTIDINE, SIMVASTATIN. Patient was hospitalized. Patient recovered.

Trisenox Side Effects Report #5081599-1
Trisenox side effect was reported by a Physician from JAPAN on July 27, 2006. Female patient, 77 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood albumin decreased, blood lactate dehydrogenase increased, c-reactive protein increased, electrocardiogram qt prolonged, fibrin d dimer increased, gamma-glutamyltransferase increased, protein total decreased. Trisenox dosage: 9.315 MG QD INTRAVENOUS DRIP. Patient recovered.

Trisenox Side Effects Report #4609439-2
Trisenox side effect was reported by a Physician from on Feb 21, 2005. Female patient, 72 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood alkaline phosphatase increased, condition aggravated, gamma-glutamyltransferase increased, hepatic function abnormal. Trisenox dosage: unknown. Patient recovered.

Trisenox Side Effects Report #4618289-2
Trisenox side effect was reported by a Physician from on Mar 02, 2005. Female patient, 72 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: acute myeloid leukaemia, alanine aminotransferase increased, aspartate aminotransferase increased, blood alkaline phosphatase increased, condition aggravated, gamma-glutamyltransferase increased, haemoglobin decreased, hepatic function abnormal. Trisenox dosage: unknown. Patient recovered.

Trisenox Side Effects Report #4675632-6
Trisenox side effect was reported by a Physician from on Feb 14, 2005. Female patient, 72 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood alkaline phosphatase increased, gamma-glutamyltransferase increased, hepatic function abnormal. Trisenox dosage: 4.8 MG (4.8 MG,), INTRAVENOUS. Patient recovered.

Trisenox Side Effects Report #4686792-5
Trisenox side effect was reported by a Physician from on May 08, 2005. Female patient, 72 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood alkaline phosphatase increased, gamma-glutamyltransferase increased, haemoglobin decreased, hepatic function abnormal. Trisenox dosage: 4.8 MG (4.8 MG) INTRAVENOUS. Patient recovered.

Trisenox Side Effects Report #4747920-6
Trisenox side effect was reported by a Physician from JAPAN on July 28, 2005. Male patient, 72 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, hepatic function abnormal. Trisenox dosage: 6 MG (6 MG), IVI. During the same period patient was treated with BIAPENEM, VANCOMYCIN, CLINDAMYCIN, CEFTAZIDIME, ALLOPURINOL, TOSUFLOXACIN, FLUCONAZOLE, FAMOTIDINE. Patient recovered.

Trisenox Side Effects Report #4752552-X
Trisenox side effect was reported by a Physician from JAPAN on Aug 04, 2005. Male patient, 72 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood lactate dehydrogenase decreased, hepatic function abnormal, hypokalaemia. Trisenox dosage: 6 MG (6 MG) IVI. During the same period patient was treated with BIAPENEM, VANCOMYCIN, CLINDAMYCIN, CEFTAZIDIME, ALLOPURINOL, TOSUFLOXACIN, FLUCONAZOLE, FAMOTIDINE. Patient recovered.

Trisenox Side Effects Report #4781090-3
Trisenox side effect was reported by a Physician from JAPAN on Sept 07, 2005. Male patient, 72 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood alkaline phosphatase increased, blood lactate dehydrogenase increased, condition aggravated, gamma-glutamyltransferase increased, hepatic function abnormal, hypokalaemia. Trisenox dosage: 6 MG (6 MG, IVI). During the same period patient was treated with BIAPENEM, VANCOMYCIN, CLINDAMYCIN, CEFTAZIDIME, ALLOPURINOL, TOSUFOXACIN, FLUCONAZOLE, FAMOTIDINE. Patient recovered.

Trisenox Side Effects Report #4950882-X
Trisenox side effect was reported by a Physician from JAPAN on Mar 01, 2006. Male patient, 72 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood lactate dehydrogenase increased, gamma-glutamyltransferase increased, hepatic function abnormal, hypokalaemia. Trisenox dosage: 6.6 MG QD INTRAVENOUS DRIP. During the same period patient was treated with BIAPENEM, TOSUFLOXACIN TOSILATE, FLUCONAZOLE, FAMOTIDINE. Patient recovered.

Trisenox Side Effects Report #5584462-2
Trisenox side effect was reported by a Physician from JAPAN on Dec 17, 2007. Male patient, 70 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, depressed level of consciousness, hepatic function abnormal, oral herpes, pancytopenia. Trisenox dosage: 8.4 MG QD INTRAVENOUS DRIP. During the same period patient was treated with CYTARABINE, PREDNISOLONE ACETATE, METHOTREXATE. Patient was hospitalized. Patient died on 12/02/2007.

Trisenox Side Effects Report #5589390-4
Trisenox side effect was reported by a Physician from JAPAN on Dec 26, 2007. Male patient, 70 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood lactate dehydrogenase increased, depressed level of consciousness, gamma-glutamyltransferase increased, herpes simplex

, pancytopenia, respiratory failure, shock. Trisenox dosage: 8.4 MG QD INTRAVENOUS DRIP. During the same period patient was treated with CYTARABINE, METHOTREXATE. Patient was hospitalized. Patient died on 12/02/2007.

Trisenox Side Effects Report #5856707-2
Trisenox side effect was reported by a Physician from JAPAN on Aug 12, 2008. Male patient, 70 years of age, weighting 158.7 lb, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, decreased appetite, diarrhoea, electrocardiogram qt prolonged, nausea

, pancytopenia. Trisenox dosage: 10.627 MG QD INTRAVENOUS DRIP. During the same period patient was treated with FLUCONAZOLE, SULFAMETHOXAZOLE AND TRIMETHOPRIM, POLAPREZINC, BROTIZOLAM. Patient recovered.

Trisenox Side Effects Report #5872002-X
Trisenox side effect was reported by a Physician from JAPAN on Aug 19, 2008. Male patient, 70 years of age, weighting 158.7 lb, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, decreased appetite, diarrhoea, electrocardiogram qt prolonged, gamma-glutamyltransferase increased, hepatic function abnormal, nausea

, pancytopenia. Trisenox dosage: 10.627 MG QD INTRAVENOUS DRIP. During the same period patient was treated with FLUCONAZOLE, SULFAMETHOXAZOLE AND TRIMETHOPRIM, POLAPREZINC, BROTIZOLAM, FOSFLUCONAZOLE. Patient was hospitalized. Patient recovered.

Trisenox Side Effects Report #5233587-X
Trisenox side effect was reported by a Physician from JAPAN on Jan 23, 2007. Female patient, 67 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, anaemia, blood lactate dehydrogenase increased, febrile neutropenia, gamma-glutamyltransferase increased, hepatic function abnormal, platelet count decreased, white blood cell count decreased. Trisenox dosage: 7.95 MG QD INTRAVENOUS DRIP. Patient recovered.

Trisenox Side Effects Report #5248064-X
Trisenox side effect was reported by a Physician from JAPAN on Feb 07, 2007. Female patient, 67 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, anaemia, aspartate aminotransferase increased, blood lactate dehydrogenase increased, febrile neutropenia, gamma-glutamyltransferase increased, hepatic function abnormal, platelet count decreased, white blood cell count decreased. Trisenox dosage: 7.95 MG QD INTRAVENOUS DRIP. Patient recovered.

Trisenox Side Effects Report #5257757-X
Trisenox side effect was reported by a Physician from JAPAN on Feb 15, 2007. Female patient, 67 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, anaemia, aspartate aminotransferase increased, blood lactate dehydrogenase increased, febrile neutropenia, gamma-glutamyltransferase increased, hepatic function abnormal, platelet count decreased, protein total decreased. Trisenox dosage: 7.95 MG QD INTRAVENOUS DRIP. Patient recovered.

Trisenox Side Effects Report #6016196-4
Trisenox side effect was reported by a Health Professional from JAPAN on Nov 13, 2008. Female patient, 66 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: acute promyelocytic leukaemia differentiation syndrome, alanine aminotransferase increased, aspartate aminotransferase increased, blood lactate dehydrogenase increased, gamma-glutamyltransferase increased, hepatic function abnormal, pericardial effusion, pseudomembranous colitis. Trisenox dosage: 4.75 MG QD INTRAVENOUS DRIP. During the same period patient was treated with ANTITHROMBIN, INSULIN. Patient recovered.

Trisenox Side Effects Report #5047198-2
Trisenox side effect was reported by a Physician from JAPAN on June 23, 2006. Male patient, 64 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood alkaline phosphatase increased, electrocardiogram qt prolonged, gamma-glutamyltransferase increased. Trisenox dosage: 8.76 MG QD INTRAVENOUS DRIP. During the same period patient was treated with CYTARABINE, IDARUBICIN, MEXILETINE HYDROCHLORIDE, GABEXATE MESILATE, AMIKACIN SULPHATE. Patient was hospitalized. Patient recovered.

Trisenox Side Effects Report #4701616-5
Trisenox side effect was reported by a Physician from on June 07, 2005. Male patient, 64 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood alkaline phosphatase increased, electrocardiogram qt prolonged. Trisenox dosage: 8.76 MG (8.76 MILLICURIES), IVI. During the same period patient was treated with MEXILETINE. Patient was hospitalized. Patient recovered.

Trisenox Side Effects Report #4831873-6
Trisenox side effect was reported by a Physician from JAPAN on Nov 01, 2005. Male patient, 64 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood alkaline phosphatase increased, electrocardiogram qt corrected interval prolonged, electrocardiogram qt prolonged. Trisenox dosage: 8.76 MG QD INTRAVENOUS. During the same period patient was treated with MEXILETINE HYDROCHLORIDE. Patient was hospitalized. Patient recovered.

Trisenox Side Effects Report #4938437-4
Trisenox side effect was reported by a Physician from JAPAN on Feb 21, 2006. Male patient, 64 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood alkaline phosphatase increased, electrocardiogram qt corrected interval prolonged, gamma-glutamyltransferase increased, hepatic function abnormal. Trisenox dosage: 8.76 MG QD INTRAVENOUS. During the same period patient was treated with MEXILETINE HYDROCHLORIDE, CYTARABINE, GABEXATE MESILATE, AMIKACIN SULPHATE. Patient was hospitalized. Patient recovered.

Trisenox Side Effects Report #5680028-4
Trisenox side effect was reported by a Physician from JAPAN on Mar 12, 2008. Male patient, 63 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, acute promyelocytic leukaemia, alanine aminotransferase increased, aspartate aminotransferase increased, blood albumin decreased, blood alkaline phosphatase increased, blood bilirubin increased, blood calcium decreased, blood lactate dehydrogenase increased. Trisenox dosage: K9.75 MG QD; INTRAVENOUS. During the same period patient was treated with ARBEKACIN SULPHATE, MEROPENEM, MEXILETINE HYDROCHLORIDE, DALTEPARIN, HYDROCORTISONE SUCCINATE, RANITIDINE HYDROCHLORIDE, ALLOPURINOL. Patient was hospitalized. Patient died on 05/10/2007.

Trisenox Side Effects Report #5701452-7
Trisenox side effect was reported by a Physician from JAPAN on Mar 24, 2008. Male patient, 63 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, acute promyelocytic leukaemia, alanine aminotransferase increased, aspartate aminotransferase increased, blood albumin decreased, blood alkaline phosphatase increased, blood bilirubin increased, blood calcium decreased, blood creatinine increased. Trisenox dosage: 9.75 MG, QD; INTRAVENOUS. During the same period patient was treated with ARBEKACIN SULPHATE, MEROPENEM TRIHYDRATE, MEROPENEM TRIHYDRATE, MEXILETINE HYDROCHLORIDE, DALTEPARIN, HYDROCORTISONE SUCCINATE, RANITIDINE HYDROCHLORIDE. Patient was hospitalized. Patient died on 05/08/2007.

Trisenox Side Effects Report #5220983-X
Trisenox side effect was reported by a Physician from JAPAN on Jan 09, 2007. Female patient, 62 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, condition aggravated, gamma-glutamyltransferase increased, hepatic function abnormal, leukocytosis. Trisenox dosage: 8.19 MG QD INTRAVENOUS DRIP. During the same period patient was treated with IDARUBICIN HDYROCHLORIDE, CYTARABINE, DANAPAROID. Patient recovered.

Trisenox Side Effects Report #5136828-2
Trisenox side effect was reported by a Physician from JAPAN on Oct 05, 2006. Female patient, 62 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, electrocardiogram qt corrected interval prolonged, electrocardiogram qt prolonged, hepatic function abnormal, white blood cell count decreased. Trisenox dosage: 6.975 MG QD INTRAVENOUS DRIP. Patient recovered.

Trisenox Side Effects Report #5706352-4
Trisenox side effect was reported by a Physician from JAPAN on Mar 31, 2008. Female patient, 61 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, gamma-glutamyltransferase increased, hepatic function abnormal. Trisenox dosage: 8.175 MG QD INTRAVENOUS DRIP. During the same period patient was treated with POLYMYXIN, SULFAMETHOXAZOLE AND TRIMETHOPRIM. Patient recovered.

Trisenox Side Effects Report #5724215-5
Trisenox side effect was reported by a Physician from JAPAN on Apr 14, 2008. Female patient, 61 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood alkaline phosphatase increased, gamma-glutamyltransferase increased, hepatic function abnormal. Trisenox dosage: 8.175 MG, QD; INTRAVENOUS DRIP. During the same period patient was treated with POLYMYXIN B SULPHATE, SULFAMETHOXAZOLE AND TRIMETHOPRIM. Patient recovered.

Trisenox Side Effects Report #5301184-3
Trisenox side effect was reported by a Physician from JAPAN on Mar 26, 2007. Female patient, 59 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, electrocardiogram qt corrected interval prolonged, hepatic function abnormal, pancytopenia. Trisenox dosage: 7.065 MG QD INTRAVENOUS DRIP. During the same period patient was treated with METHOTREXATE, PREDNISOLONE ACETATE. Patient recovered.

Trisenox Side Effects Report #5757804-2
Trisenox side effect was reported by a Physician from FRANCE on May 15, 2008. Female patient, 59 years of age, weighting 130.1 lb, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: abscess

, alanine aminotransferase increased, aplasia, aspartate aminotransferase increased, blood bilirubin increased, blood chloride decreased, blood potassium decreased, blood pressure diastolic decreased, blood sodium decreased. Trisenox dosage: 9 MG DAILY 5 DAYS EVERY 7 DAYS FOR 35 DAYS INTRAVENOUS. During the same period patient was treated with ZOVIRAX, TAZOCILLINE, TARGOCID, IDARUBICIN, CYTARABINE. Patient was hospitalized. Patient died on 04/13/2008.

Trisenox Side Effects Report #5125019-7
Trisenox side effect was reported by a Physician from JAPAN on Sept 22, 2006. Male patient, 58 years of age, weighting 132.3 lb, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, blood bilirubin increased, cerebral haemorrhage, condition aggravated, disseminated intravascular coagulation, hepatic function abnormal, hypercalcaemia, hyperglycaemia, hyponatraemia. Trisenox dosage: 9 MG QD INTRAVENOUS DRIP. During the same period patient was treated with GABEXATE MESILATE, DANAPAROID, FUROSEMIDE, VORICONAZOLE, SULFAMETHOXAZOLE. Patient was hospitalized. Patient died on 05/16/2006.

Trisenox Side Effects Report #5179504-2
Trisenox side effect was reported by a Physician from JAPAN on Nov 30, 2006. Male patient, 58 years of age, weighting 132.3 lb, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, blood bilirubin increased, cerebral haemorrhage, condition aggravated, disseminated intravascular coagulation, febrile neutropenia, fungal infection

, hepatic function abnormal, hypercalcaemia. Trisenox dosage: 9 MG QD INTRAVENOUS DRIP. During the same period patient was treated with GABEXATE MESILATE, DANAPAROID, FUROSEMIDE, VORICONAZOLE, SULFAMETHOXAZOLE W. Patient was hospitalized. Patient died on 05/16/2006.

Trisenox Side Effects Report #5401990-0
Trisenox side effect was reported by a Physician from JAPAN on July 10, 2007. Female patient, 58 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, back pain

, bone pain, disseminated intravascular coagulation, electrocardiogram qt prolonged, hypercalcaemia, hyperglycaemia, hyperkalaemia. Trisenox dosage: 7.5 MG QD INTRAVENOUS DRIP. During the same period patient was treated with IDARUBICIN, NAFAMOSTAT MESILATE, GLUCOSE W, ELECTROLYTE, PARENTERAL FLUID OF HIGH, INSULIN. Patient was hospitalized. Patient recovered.

Trisenox Side Effects Report #5408384-2
Trisenox side effect was reported by a Physician from JAPAN on July 25, 2007. Female patient, 58 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, back disorder, blood alkaline phosphatase increased, blood lactate dehydrogenase increased, bone pain, disseminated intravascular coagulation, electrocardiogram qt prolonged, gamma-glutamyltransferase increased. Trisenox dosage: 7.245 MG QD INTRAVENOUS DRIP. During the same period patient was treated with IDARUBICIN, NAFAMOSTAT MESILATE, GLUCOSE W, ELECTROLYTE, PARENTERAL FLUID OF HIGH, INSULIN. Patient recovered.

Trisenox Side Effects Report #5483251-7
Trisenox side effect was reported by a Physician from JAPAN on Sept 27, 2007. Female patient, 58 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: acute promyelocytic leukaemia differentiation syndrome, alanine aminotransferase increased, blood creatine phosphokinase increased, haemolysis, hepatic function abnormal, hyperglycaemia, renal impairment, retinoic acid syndrome. Trisenox dosage: 8.85 MG QD INTRAVENOUS DRIP. During the same period patient was treated with IDARUBICIN, POTASSIUM SUPPLEMENT, GABEXATE MESILATE, CARPERITIDE, MICAFUNGIN. Patient recovered.

Trisenox Side Effects Report #5632251-2
Trisenox side effect was reported by a Physician from JAPAN on Jan 28, 2008. Female patient, 58 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: acute promyelocytic leukaemia differentiation syndrome, alanine aminotransferase increased, aspartate aminotransferase increased, blood creatine phosphokinase increased, blood creatinine increased, blood lactate dehydrogenase increased, blood potassium decreased, dyspnoea, electrocardiogram qt prolonged. Trisenox dosage: 8.85 MG QD INTRAVENOUS DRIP. During the same period patient was treated with IDARUBICIN, POTASSIUM SUPPLEMENT, GABEXATE MESILATE, CARPERITIDE, MICAFUNGIN. Patient was hospitalized. Patient recovered.

Trisenox Side Effects Report #5718737-0
Trisenox side effect was reported by a Physician from JAPAN on Apr 10, 2008. Female patient, 58 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: acute promyelocytic leukaemia differentiation syndrome, alanine aminotransferase increased, aspartate aminotransferase increased, blood bilirubin increased, blood lactate dehydrogenase increased, blood potassium decreased, blood urea increased, electrocardiogram qt prolonged, gamma-glutamyltransferase increased. Trisenox dosage: 8.85 MG QD INTRAVENOUS DRIP. During the same period patient was treated with IDARUBICIN, POTASSIUM SUPPLEMENT, GABEXATE MESILATE, CARPERITIDE, MICAFUNGIN. Patient was hospitalized. Patient recovered.

Trisenox Side Effects Report #5266132-3
Trisenox side effect was reported by a Physician from JAPAN on Feb 27, 2007. Female patient, 57 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: acute promyelocytic leukaemia differentiation syndrome, alanine aminotransferase increased, aspartate aminotransferase increased, blood alkaline phosphatase increased, blood bilirubin increased, blood lactate dehydrogenase increased, c-reactive protein increased, condition aggravated, disseminated intravascular coagulation. Trisenox dosage: unknown. During the same period patient was treated with CYTARABINE, IDARUBICIN, DANAPAROID, CARBAZOCHROME SULFONATE, TRANEXAMIC ACID, MONOAMMONIUM GLYCYRRHIZINATE. Patient died on 12/31/2006.

Trisenox Side Effects Report #5320867-2
Trisenox side effect was reported by a Physician from JAPAN on Apr 24, 2007. Female patient, 57 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood bilirubin increased, electrocardiogram qt prolonged, hepatic function abnormal, herpes zoster, white blood cell count decreased. Trisenox dosage: 8.475 MG QD INTRAVENOUS DRIP. During the same period patient was treated with RANITIDINE HYDROCHLORIDE, ALLOPURINOL, PRAVASTATIN, SULFAMETHOXAZOLE AND TRIMETHOPRIM, BROTIZOLAM, ETIZOLAM. Patient was hospitalized. Patient recovered.

Trisenox Side Effects Report #5087025-0
Trisenox side effect was reported by a Physician from JAPAN on Aug 09, 2006. Female patient, 57 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, c-reactive protein increased, headache

, hepatic function abnormal, platelet count decreased, rash

, white blood cell count decreased. Trisenox dosage: 7.77 MG QD INTRAVENOUS DRIP. Patient recovered.

Trisenox Side Effects Report #5147069-7
Trisenox side effect was reported by a Physician from JAPAN on Oct 20, 2006. Female patient, 57 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, electrocardiogram qt prolonged, hepatic function abnormal, herpes zoster, white blood cell count decreased. Trisenox dosage: 8.475 MG QD INTRAVENOUS DRIP. During the same period patient was treated with RANITIDINE HYDROCHLORIDE, ALLOPURINOL, PRAVASTATIN, SULFAMETHOXAZOLE, BROTIZOLAM, ETIZOLAM. Patient was hospitalized. Patient recovered.

Trisenox Side Effects Report #5107289-4
Trisenox side effect was reported by a Physician from JAPAN on Aug 30, 2006. Male patient, 53 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood calcium decreased, blood magnesium decreased, blood sodium decreased, neutrophil count decreased. Trisenox dosage: 4.425 MG QD INTRAVENOUS DRIP. During the same period patient was treated with GABEXATE MESILATE. Patient recovered.

Trisenox Side Effects Report #5116821-6
Trisenox side effect was reported by a Physician from JAPAN on Sept 08, 2006. Male patient, 53 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood calcium decreased, blood magnesium decreased, blood sodium decreased, neutrophil count decreased, white blood cell count decreased. Trisenox dosage: 4.425 MG QD INTRAVENOUS DRIP. During the same period patient was treated with GABEXATE MESILATE. Patient recovered.

Trisenox Side Effects Report #5133972-0
Trisenox side effect was reported by a Physician from JAPAN on Oct 02, 2006. Female patient, 53 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, electrocardiogram qt prolonged, hepatic function abnormal, red blood cell count decreased, white blood cell count decreased. Trisenox dosage: 7.35 MG QD INTRAVENOUS DRIP. Patient recovered.

Trisenox Side Effects Report #5179503-0
Trisenox side effect was reported by a Physician from JAPAN on Nov 29, 2006. Female patient, 53 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, electrocardiogram qt prolonged, haemoglobin decreased, hepatic function abnormal, red blood cell count decreased, white blood cell count decreased. Trisenox dosage: 7.35 MG QD INTRAVENOUS DRIP. Patient recovered.

Trisenox Side Effects Report #5635741-1
Trisenox side effect was reported by a Physician from JAPAN on Feb 05, 2008. Male patient, 53 years of age, was diagnosed with acute promyelocytic leukaemia, convulsion prophylaxis and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, blister, convulsion, electrocardiogram qt prolonged, hepatic function abnormal, herpes zoster, meningitis

, pancytopenia, pseudomonas infection. Trisenox dosage: 10.425 MG,QD,INTRAVENOUS DRIP. During the same period patient was treated with VALPROATE, CYTARABINE, METHOTREXATE, PREDNISOLONE ACETATE, NAFAMOSTATE. Patient was hospitalized. Patient recovered.

Trisenox Side Effects Report #5643136-X
Trisenox side effect was reported by a Physician from JAPAN on Feb 13, 2008. Male patient, 53 years of age, was diagnosed with acute promyelocytic leukaemia, convulsion prophylaxis and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, catheter site infection, central nervous system leukaemia, electrocardiogram qt prolonged, hepatic function abnormal, herpes zoster, meningitis

, pancytopenia, pseudomonas infection. Trisenox dosage: 10.425 MG QD INTRAVENOUS DRIP. During the same period patient was treated with VALPROATE, CYTARABINE, METHOTREXATE, PREDNISOLONE ACETATE, NAFAMOSTATE. Patient was hospitalized. Patient recovered.

Trisenox Side Effects Report #5701451-5
Trisenox side effect was reported by a Health Professional from JAPAN on Mar 24, 2008. Male patient, 53 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, electrocardiogram qt prolonged, hepatic function abnormal, pancytopenia. Trisenox dosage: 10.095 MG QD INTRAVENOUS DRIP. During the same period patient was treated with CYTARABINE, METHOTREXATE, PREDNISOLONE. Patient recovered.

Trisenox Side Effects Report #5320869-6
Trisenox side effect was reported by a Physician from JAPAN on Apr 23, 2007. Male patient, 50 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, csf test abnormal, cytology abnormal, gamma-glutamyltransferase increased, hepatic function abnormal. Trisenox dosage: 9.48 MG QD INTRAVENOUS DRIP. During the same period patient was treated with FLUCONAZOLE, FAMOTIDINE. Patient recovered.

Trisenox Side Effects Report #6088508-7
Trisenox side effect was reported by a Physician from JAPAN on Feb 09, 2009. Male patient, 46 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, blood alkaline phosphatase increased, haemoglobin decreased, hepatic function abnormal, platelet count decreased, white blood cell count decreased. Trisenox dosage: 7.65 MG QD; INTRAVENOUS DRIP. During the same period patient was treated with CYTARABINE, METHOTREXATE, DEXAMETHASONE PHOSPHATE, FILGRASTIM. Patient was hospitalized. Patient recovered.

Trisenox Side Effects Report #6108579-9
Trisenox side effect was reported by a Health Professional from JAPAN on Feb 19, 2009. Male patient, 46 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, blood alkaline phosphatase increased, haemoglobin decreased, hepatic function abnormal, platelet count decreased, white blood cell count decreased. Trisenox dosage: 7.65 MG QD INTRAVENOUS DRIP. During the same period patient was treated with CYTARABINE, METHOTREXATE, DEXAMETHASONE PHOSPHATE, FILGRASTIM. Patient was hospitalized and became disabled. Patient recovered.

Trisenox Side Effects Report #5913581-3
Trisenox side effect was reported by a Physician from JAPAN on Sept 24, 2008. Female patient, 43 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, electrocardiogram qt prolonged, hepatic function abnormal, hyperglycaemia, ventricular extrasystoles, white blood cell count decreased. Trisenox dosage: 10.2 MG QD INTRAVENOUS DRIP. Patient was hospitalized. Patient recovered.

Trisenox Side Effects Report #5817327-9
Trisenox side effect was reported by a Physician from JAPAN on July 01, 2008. Male patient, 42 years of age, weighting 133.8 lb, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: acute promyelocytic leukaemia differentiation syndrome, alanine aminotransferase increased, blood potassium decreased, blood sodium decreased, hepatic function abnormal, hyperglycaemia, hyperuricaemia, hypoalbuminaemia, hypoproteinaemia. Trisenox dosage: 8.7 MG DAILY; INTRAVENOUS DRIP. During the same period patient was treated with IDARUBICIN HYDROCHLORIDE, LANSOPRAZOLE, ITRACONAZOLE. Patient recovered.

Trisenox Side Effects Report #5933636-7
Trisenox side effect was reported by a Physician from JAPAN on Oct 16, 2008. Male patient, 42 years of age, weighting 133.8 lb, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: acute promyelocytic leukaemia differentiation syndrome, alanine aminotransferase increased, aspartate aminotransferase increased, blood lactate dehydrogenase increased, cardiomegaly, gamma-glutamyltransferase increased, hyperglycaemia, hyperuricaemia, hypoalbuminaemia. Trisenox dosage: 8.7 MG QD INTRAVENOUS DRIP. During the same period patient was treated with DEXAMETHASONE PHOSPHATE, DEXAMETHASONE PHOSPHATE, DEXAMETHASONE PHOSPHATE, IDARUBICIN HYDROCHLORIDE, LANSOPRAZOLE, ITRACONAZOLE. Patient recovered.

Trisenox Side Effects Report #5102981-X
Trisenox side effect was reported by a Physician from JAPAN on Aug 23, 2006. Male patient, 39 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, electrocardiogram qt corrected interval prolonged, hepatic function abnormal, hypernatraemia, hypokalaemia, white blood cell count decreased. Trisenox dosage: 10.98 MG QD INTRAVENOUS DRIP. During the same period patient was treated with CYTARABINE, METHOTREXATE, DEXAMETHASONE PHOSPHATE, ELECTROLYTE SOLUTION, RANITIDINE HYDROCHLORIDE. Patient recovered.

Trisenox Side Effects Report #5486001-3
Trisenox side effect was reported by a Physician from JAPAN on Oct 01, 2007. Female patient, 38 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, gamma-glutamyltransferase increased, oedema, weight increased. Trisenox dosage: unknown. Patient recovered.

Trisenox Side Effects Report #5556932-4
Trisenox side effect was reported by a Physician from JAPAN on Nov 26, 2007. Female patient, 38 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase decreased, blood magnesium decreased, blood potassium decreased, electrocardiogram qt prolonged, gamma-glutamyltransferase increased, hepatic function abnormal, oedema, rash

. Trisenox dosage: 8.55 MG QD; INTRAVENOUS DRIP. During the same period patient was treated with GLYCYRRHIZIN, MAGNESIUM REPLACEMENT, POTASSIUM REPLACEMENT, HYDROCORTISONE SUCCINATE, PREDNISOLONE, SPIRONOLACTONE, FUROSEMIDE. Patient recovered.

Trisenox Side Effects Report #5635799-X
Trisenox side effect was reported by a Physician from JAPAN on Feb 07, 2008. Female patient, 38 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood magnesium decreased, blood potassium decreased, electrocardiogram qt prolonged, gamma-glutamyltransferase increased, hepatic function abnormal, oedema, rash

. Trisenox dosage: 8.55 MG QD INTRAVENOUS DRIP. During the same period patient was treated with GLYCYRRHIZIN, MAGNESIUM REPLACEMENT, POTASSIUM REPLACEMENT, HYDROCORTISONE SUCCINATE, PREDNISOLONE, SPIRONOLACTONE, FUROSEMIDE. Patient recovered.

Trisenox Side Effects Report #5301086-2
Trisenox side effect was reported by a Physician from JAPAN on Mar 26, 2007. Female patient, 37 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: accelerated idioventricular rhythm, alanine aminotransferase increased, alopecia, aspartate aminotransferase increased, c-reactive protein increased, electrocardiogram qt corrected interval prolonged, gamma-glutamyltransferase increased, leukocytosis, nausea

. Trisenox dosage: 8.978 MG QD INTRAVENOUS DRIP. During the same period patient was treated with MEXILETINE HYDROCHLORIDE, GRANISETRN HYDROCHLORIDE. Patient recovered.

Trisenox Side Effects Report #5175210-9
Trisenox side effect was reported by a Physician from JAPAN on Nov 22, 2006. Female patient, 37 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: accelerated idioventricular rhythm, acute promyelocytic leukaemia differentiation syndrome, alanine aminotransferase increased, alopecia, aspartate aminotransferase increased, blood lactate dehydrogenase increased, c-reactive protein increased, electrocardiogram qt corrected interval prolonged, gamma-glutamyltransferase increased. Trisenox dosage: 8.978 MG QD INTRAVENOUS DRIP. During the same period patient was treated with MEXILETINE HYDROCHLORIDE, GRANISETRON. Patient recovered.

Trisenox Side Effects Report #4650014-1
Trisenox side effect was reported by a Physician from on Apr 11, 2005. Female patient, 35 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, white blood cell count decreased. Trisenox dosage: (10.38 MG, QD, 5X/WK), IVI. During the same period patient was treated with CLINDAMYCIN, PHENOBARBITAL, TERPRENONE. Patient was hospitalized. Patient recovered.

Trisenox Side Effects Report #5698243-2
Trisenox side effect was reported by a Physician from JAPAN on Mar 21, 2008. Male patient, 34 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, ventricular extrasystoles. Trisenox dosage: 12 MG QD; INTRAVENOUS DRIP. Patient was hospitalized. Patient recovered.

Trisenox Side Effects Report #5260932-1
Trisenox side effect was reported by a Physician from JAPAN on Feb 20, 2007. Female patient, 32 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood lactate dehydrogenase decreased, blood urea decreased, electrocardiogram qt corrected interval prolonged, hepatic function abnormal, protein total decreased, rash

, white blood cell count decreased. Trisenox dosage: 7.05 MG QD INTRAVENOUS DRIP. During the same period patient was treated with ELECTROLYTE. Patient was hospitalized. Patient recovered.

Trisenox Side Effects Report #5397292-1
Trisenox side effect was reported by a Physician from JAPAN on July 05, 2007. Female patient, 32 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, c-reactive protein increased, electrocardiogram qt prolonged, hepatic function abnormal, hypocalcaemia, pancytopenia. Trisenox dosage: 9.15 MG QD INTRAVENOUS DRIP. During the same period patient was treated with FEXOFENADINE HYDROCHLORIDE, RANITIDINE HYDROCHLORIDE, GEFARNATE, ETIZOLAM, ZOLPIDEM TARTRATE. Patient recovered.

Trisenox Side Effects Report #5084862-3
Trisenox side effect was reported by a Physician from JAPAN on Aug 01, 2006. Male patient, 30 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, c-reactive protein increased, electrocardiogram qt prolonged, febrile neutropenia, white blood cell count decreased. Trisenox dosage: 8.43 MG QD INTRAVENOUS DRIP. During the same period patient was treated with IMIPENEM CILASTATIN, BIFIDOBACTERIUM, LOPERAMIDE HYDROCHLORIDE, CEFEPIME DIHYDROCHLORIDE. Patient was hospitalized. Patient recovered.

Trisenox Side Effects Report #5574034-8
Trisenox side effect was reported by a Physician from JAPAN on Dec 14, 2007. Male patient, 28 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood lactate dehydrogenase increased, electrocardiogram qt prolonged, gamma-glutamyltransferase increased, haemoglobin decreased, tonsillitis. Trisenox dosage: 12 MG QD; INTRAVENOUS DRIP. During the same period patient was treated with DALTEPARIN, SULFAMETHOXAZOLE AND TRIMETHOPRIM, FLUCONAZOLE, OMEPRAZOLE, ROXATIDINE ACETATE, FAMOTIDINE. Patient recovered.

Trisenox Side Effects Report #5580740-1
Trisenox side effect was reported by a Physician from JAPAN on Dec 06, 2007. Male patient, 28 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood lactate dehydrogenase increased, c-reactive protein increased, electrocardiogram qt prolonged, gamma-glutamyltransferase increased, haemoglobin decreased, hepatic function abnormal, tonsillitis. Trisenox dosage: 12 MG QD INTRAVENOUS DRIP. During the same period patient was treated with DALTEPARIN, SULFAMETHOXAZOLE AND TRIMETHOPRIM, FLUCONAZOLE, OMEPRAZOLE, ROXATIDINE ACETATE, FAMOTIDINE. Patient was hospitalized. Patient recovered.

Trisenox Side Effects Report #5497267-8
Trisenox side effect was reported by a Physician from JAPAN on Oct 10, 2007. Female patient, 27 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: acute promyelocytic leukaemia differentiation syndrome, alanine aminotransferase increased, aspartate aminotransferase increased, electrocardiogram qt prolonged, haemoglobin decreased, hepatic function abnormal, hypokalaemia, leukocytosis, platelet count decreased. Trisenox dosage: 7.8 MG QD INTRAVENOUS DRIP. During the same period patient was treated with ELECTROLYTE, IDARUBICIN, PANIPENEM, AMIKACIN SULPHATE, MICAFUNGIN, ABREKACIN SULPHATE, MEROPENEM HYDRATE. Patient recovered.

Trisenox Side Effects Report #5525457-4
Trisenox side effect was reported by a Physician from JAPAN on Nov 05, 2007. Female patient, 27 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: acute promyelocytic leukaemia differentiation syndrome, alanine aminotransferase increased, aspartate aminotransferase increased, electrocardiogram qt prolonged, haemoglobin decreased, hepatic function abnormal, hypokalaemia, leukocytosis, platelet count decreased. Trisenox dosage: 7.8 MG QD INTRAVENOUS DRIP. During the same period patient was treated with IDARUBICIN, PANIPENEM, AMIKACIN SULPHATE, MICAFUNGIN, ARBEKACIN SULPHATE, MEROPENEM HYDRATE. Patient recovered.

Trisenox Side Effects Report #6025183-1
Trisenox side effect was reported by a Health Professional from JAPAN on Dec 17, 2008. Female patient, 17 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, hepatic function abnormal. Trisenox dosage: 7.05 MG DAILY; INTRAVENOUS DRIP. Patient recovered.

Trisenox Side Effects Report #5507315-4
Trisenox side effect was reported by a Physician from JAPAN on Oct 22, 2007. Female patient was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, electrocardiogram qt prolonged, gamma-glutamyltransferase increased, hepatic function abnormal, oedema, rash

, weight increased. Trisenox dosage: 8.55 MG QD INTRAVENOUS DRIP. During the same period patient was treated with HYDROCORTISONE SUCCINATE, PREDNISOLONE, SPIRONOLACTONE, FUROSEMIDE. Patient recovered.

Trisenox Side Effects Report #5586192-X
Trisenox side effect was reported by a Physician from UNITED STATES on July 27, 2007. Male patient was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, neutropenia. Trisenox dosage: 12 MG DAILY MONDAY-FRIDAY INTRAVENOUS DRIP. During the same period patient was treated with ALLOPURINOL, BACLOFEN, VICODIN, RESTORIL, POTASSIUM CHLORIDE, COMPAZINE, RANITIDINE. Patient recovered.

Trisenox Side Effects Report #5912529-5
Trisenox side effect was reported by a Physician from JAPAN on Aug 22, 2008. Male patient, 83 years of age, was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, altered state of consciousness, aspartate aminotransferase increased, asterixis, dialysis

, hepatic function abnormal, tubulointerstitial nephritis. Trisenox dosage: unknown. Patient recovered.

Trisenox Side Effects Report #5574047-6
Trisenox side effect was reported by a Physician from JAPAN on Dec 12, 2007. Male patient, 70 years of age, was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, dry mouth, herpes simplex

, oral intake reduced, pancytopenia. Trisenox dosage: unknown. Patient died on 11/25/2007.

Trisenox Side Effects Report #5588255-1
Trisenox side effect was reported by a Physician from JAPAN on Dec 26, 2007. Female patient was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, electrocardiogram qt prolonged, enteritis, hepatic function abnormal, pancytopenia. Trisenox dosage: unknown. Patient recovered.

Trisenox and alanine aminotransferase increased

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Trisenox and alanine aminotransferase increased Patient Reports February 10, 2010

side effects of Trisenox