Trisenox and hepatic function abnormal Patient Reports March 16, 2010

Trisenox Side Effects Report #5768221-3
Trisenox side effect was reported by a Physician from JAPAN on May 26, 2008. Male patient, 85 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, diarrhoea, electrocardiogram qt prolonged, hepatic function abnormal, hyperglycaemia, leukocytosis, pleural effusion, pneumonia

. Trisenox dosage: 8.4 MG DAILY INTRAVENOUS. During the same period patient was treated with GABAXATE MESILATE. Patient recovered.

Trisenox Side Effects Report #5608248-5
Trisenox side effect was reported by a Physician from JAPAN on Jan 11, 2008. Male patient, 80 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, electrocardiogram qt prolonged, enterocolitis, hepatic function abnormal, pancytopenia, renal impairment. Trisenox dosage: unknown. Patient was hospitalized. Patient recovered.

Trisenox Side Effects Report #5671610-9
Trisenox side effect was reported by a Physician from JAPAN on Feb 29, 2008. Male patient, 80 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, electrocardiogram qt prolonged, enterocolitis, hepatic function abnormal, pancytopenia, renal impairment. Trisenox dosage: 8.25 MG QD INTRAVENOUS DRIP. During the same period patient was treated with DISOPYRAMIDE PHOSPHATE, MEXILETINE HYDROCHLORIDE. Patient was hospitalized. Patient recovered.

Trisenox Side Effects Report #5270157-1
Trisenox side effect was reported by a Physician from JAPAN on Feb 28, 2007. Male patient, 79 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, electrocardiogram qt prolonged, facial palsy, hepatic function abnormal, herpes zoster, liver disorder, rash

. Trisenox dosage: 8.0625MG. During the same period patient was treated with DISOPYRAMIDE PHOSPHATE, MEXILETINE HYDROCHLORIDE, NIFEDIPINE, HALOXAZOLAM, ZOLPIDEM TARTRATE. Patient was hospitalized and became disabled. Patient recovered.

Trisenox Side Effects Report #4609439-2
Trisenox side effect was reported by a Physician from on Feb 21, 2005. Female patient, 72 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood alkaline phosphatase increased, condition aggravated, gamma-glutamyltransferase increased, hepatic function abnormal. Trisenox dosage: unknown. Patient recovered.

Trisenox Side Effects Report #4618289-2
Trisenox side effect was reported by a Physician from on Mar 02, 2005. Female patient, 72 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: acute myeloid leukaemia, alanine aminotransferase increased, aspartate aminotransferase increased, blood alkaline phosphatase increased, condition aggravated, gamma-glutamyltransferase increased, haemoglobin decreased, hepatic function abnormal. Trisenox dosage: unknown. Patient recovered.

Trisenox Side Effects Report #4675632-6
Trisenox side effect was reported by a Physician from on Feb 14, 2005. Female patient, 72 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood alkaline phosphatase increased, gamma-glutamyltransferase increased, hepatic function abnormal. Trisenox dosage: 4.8 MG (4.8 MG,), INTRAVENOUS. Patient recovered.

Trisenox Side Effects Report #4686792-5
Trisenox side effect was reported by a Physician from on May 08, 2005. Female patient, 72 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood alkaline phosphatase increased, gamma-glutamyltransferase increased, haemoglobin decreased, hepatic function abnormal. Trisenox dosage: 4.8 MG (4.8 MG) INTRAVENOUS. Patient recovered.

Trisenox Side Effects Report #4747920-6
Trisenox side effect was reported by a Physician from JAPAN on July 28, 2005. Male patient, 72 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, hepatic function abnormal. Trisenox dosage: 6 MG (6 MG), IVI. During the same period patient was treated with BIAPENEM, VANCOMYCIN, CLINDAMYCIN, CEFTAZIDIME, ALLOPURINOL, TOSUFLOXACIN, FLUCONAZOLE, FAMOTIDINE. Patient recovered.

Trisenox Side Effects Report #4752552-X
Trisenox side effect was reported by a Physician from JAPAN on Aug 04, 2005. Male patient, 72 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood lactate dehydrogenase decreased, hepatic function abnormal, hypokalaemia. Trisenox dosage: 6 MG (6 MG) IVI. During the same period patient was treated with BIAPENEM, VANCOMYCIN, CLINDAMYCIN, CEFTAZIDIME, ALLOPURINOL, TOSUFLOXACIN, FLUCONAZOLE, FAMOTIDINE. Patient recovered.

Trisenox Side Effects Report #4781090-3
Trisenox side effect was reported by a Physician from JAPAN on Sept 07, 2005. Male patient, 72 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood alkaline phosphatase increased, blood lactate dehydrogenase increased, condition aggravated, gamma-glutamyltransferase increased, hepatic function abnormal, hypokalaemia. Trisenox dosage: 6 MG (6 MG, IVI). During the same period patient was treated with BIAPENEM, VANCOMYCIN, CLINDAMYCIN, CEFTAZIDIME, ALLOPURINOL, TOSUFOXACIN, FLUCONAZOLE, FAMOTIDINE. Patient recovered.

Trisenox Side Effects Report #4950882-X
Trisenox side effect was reported by a Physician from JAPAN on Mar 01, 2006. Male patient, 72 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood lactate dehydrogenase increased, gamma-glutamyltransferase increased, hepatic function abnormal, hypokalaemia. Trisenox dosage: 6.6 MG QD INTRAVENOUS DRIP. During the same period patient was treated with BIAPENEM, TOSUFLOXACIN TOSILATE, FLUCONAZOLE, FAMOTIDINE. Patient recovered.

Trisenox Side Effects Report #5584462-2
Trisenox side effect was reported by a Physician from JAPAN on Dec 17, 2007. Male patient, 70 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, depressed level of consciousness, hepatic function abnormal, oral herpes, pancytopenia. Trisenox dosage: 8.4 MG QD INTRAVENOUS DRIP. During the same period patient was treated with CYTARABINE, PREDNISOLONE ACETATE, METHOTREXATE. Patient was hospitalized. Patient died on 12/02/2007.

Trisenox Side Effects Report #5872002-X
Trisenox side effect was reported by a Physician from JAPAN on Aug 19, 2008. Male patient, 70 years of age, weighting 158.7 lb, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, decreased appetite, diarrhoea, electrocardiogram qt prolonged, gamma-glutamyltransferase increased, hepatic function abnormal, nausea

, pancytopenia. Trisenox dosage: 10.627 MG QD INTRAVENOUS DRIP. During the same period patient was treated with FLUCONAZOLE, SULFAMETHOXAZOLE AND TRIMETHOPRIM, POLAPREZINC, BROTIZOLAM, FOSFLUCONAZOLE. Patient was hospitalized. Patient recovered.

Trisenox Side Effects Report #5233587-X
Trisenox side effect was reported by a Physician from JAPAN on Jan 23, 2007. Female patient, 67 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, anaemia, blood lactate dehydrogenase increased, febrile neutropenia, gamma-glutamyltransferase increased, hepatic function abnormal, platelet count decreased, white blood cell count decreased. Trisenox dosage: 7.95 MG QD INTRAVENOUS DRIP. Patient recovered.

Trisenox Side Effects Report #5248064-X
Trisenox side effect was reported by a Physician from JAPAN on Feb 07, 2007. Female patient, 67 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, anaemia, aspartate aminotransferase increased, blood lactate dehydrogenase increased, febrile neutropenia, gamma-glutamyltransferase increased, hepatic function abnormal, platelet count decreased, white blood cell count decreased. Trisenox dosage: 7.95 MG QD INTRAVENOUS DRIP. Patient recovered.

Trisenox Side Effects Report #5257757-X
Trisenox side effect was reported by a Physician from JAPAN on Feb 15, 2007. Female patient, 67 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, anaemia, aspartate aminotransferase increased, blood lactate dehydrogenase increased, febrile neutropenia, gamma-glutamyltransferase increased, hepatic function abnormal, platelet count decreased, protein total decreased. Trisenox dosage: 7.95 MG QD INTRAVENOUS DRIP. Patient recovered.

Trisenox Side Effects Report #6016196-4
Trisenox side effect was reported by a Health Professional from JAPAN on Nov 13, 2008. Female patient, 66 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: acute promyelocytic leukaemia differentiation syndrome, alanine aminotransferase increased, aspartate aminotransferase increased, blood lactate dehydrogenase increased, gamma-glutamyltransferase increased, hepatic function abnormal, pericardial effusion, pseudomembranous colitis. Trisenox dosage: 4.75 MG QD INTRAVENOUS DRIP. During the same period patient was treated with ANTITHROMBIN, INSULIN. Patient recovered.

Trisenox Side Effects Report #4938437-4
Trisenox side effect was reported by a Physician from JAPAN on Feb 21, 2006. Male patient, 64 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood alkaline phosphatase increased, electrocardiogram qt corrected interval prolonged, gamma-glutamyltransferase increased, hepatic function abnormal. Trisenox dosage: 8.76 MG QD INTRAVENOUS. During the same period patient was treated with MEXILETINE HYDROCHLORIDE, CYTARABINE, GABEXATE MESILATE, AMIKACIN SULPHATE. Patient was hospitalized. Patient recovered.

Trisenox Side Effects Report #5220983-X
Trisenox side effect was reported by a Physician from JAPAN on Jan 09, 2007. Female patient, 62 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, condition aggravated, gamma-glutamyltransferase increased, hepatic function abnormal, leukocytosis. Trisenox dosage: 8.19 MG QD INTRAVENOUS DRIP. During the same period patient was treated with IDARUBICIN HDYROCHLORIDE, CYTARABINE, DANAPAROID. Patient recovered.

Trisenox Side Effects Report #5136828-2
Trisenox side effect was reported by a Physician from JAPAN on Oct 05, 2006. Female patient, 62 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, electrocardiogram qt corrected interval prolonged, electrocardiogram qt prolonged, hepatic function abnormal, white blood cell count decreased. Trisenox dosage: 6.975 MG QD INTRAVENOUS DRIP. Patient recovered.

Trisenox Side Effects Report #5127284-9
Trisenox side effect was reported by a Physician from JAPAN on Sept 26, 2006. Female patient, 61 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: aspartate aminotransferase increased, c-reactive protein increased, condition aggravated, electrocardiogram qt prolonged, hepatic function abnormal, rash

, white blood cell count decreased. Trisenox dosage: 9.15 MG QD INTRAVENOUS DRIP. During the same period patient was treated with SULFAMETHOXAZOLE, FLUCONAZOLE. Patient recovered.

Trisenox Side Effects Report #5706352-4
Trisenox side effect was reported by a Physician from JAPAN on Mar 31, 2008. Female patient, 61 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, gamma-glutamyltransferase increased, hepatic function abnormal. Trisenox dosage: 8.175 MG QD INTRAVENOUS DRIP. During the same period patient was treated with POLYMYXIN, SULFAMETHOXAZOLE AND TRIMETHOPRIM. Patient recovered.

Trisenox Side Effects Report #5724215-5
Trisenox side effect was reported by a Physician from JAPAN on Apr 14, 2008. Female patient, 61 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood alkaline phosphatase increased, gamma-glutamyltransferase increased, hepatic function abnormal. Trisenox dosage: 8.175 MG, QD; INTRAVENOUS DRIP. During the same period patient was treated with POLYMYXIN B SULPHATE, SULFAMETHOXAZOLE AND TRIMETHOPRIM. Patient recovered.

Trisenox Side Effects Report #5301184-3
Trisenox side effect was reported by a Physician from JAPAN on Mar 26, 2007. Female patient, 59 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, electrocardiogram qt corrected interval prolonged, hepatic function abnormal, pancytopenia. Trisenox dosage: 7.065 MG QD INTRAVENOUS DRIP. During the same period patient was treated with METHOTREXATE, PREDNISOLONE ACETATE. Patient recovered.

Trisenox Side Effects Report #5125019-7
Trisenox side effect was reported by a Physician from JAPAN on Sept 22, 2006. Male patient, 58 years of age, weighting 132.3 lb, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, blood bilirubin increased, cerebral haemorrhage, condition aggravated, disseminated intravascular coagulation, hepatic function abnormal, hypercalcaemia, hyperglycaemia, hyponatraemia. Trisenox dosage: 9 MG QD INTRAVENOUS DRIP. During the same period patient was treated with GABEXATE MESILATE, DANAPAROID, FUROSEMIDE, VORICONAZOLE, SULFAMETHOXAZOLE. Patient was hospitalized. Patient died on 05/16/2006.

Trisenox Side Effects Report #5179504-2
Trisenox side effect was reported by a Physician from JAPAN on Nov 30, 2006. Male patient, 58 years of age, weighting 132.3 lb, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, blood bilirubin increased, cerebral haemorrhage, condition aggravated, disseminated intravascular coagulation, febrile neutropenia, fungal infection

, hepatic function abnormal, hypercalcaemia. Trisenox dosage: 9 MG QD INTRAVENOUS DRIP. During the same period patient was treated with GABEXATE MESILATE, DANAPAROID, FUROSEMIDE, VORICONAZOLE, SULFAMETHOXAZOLE W. Patient was hospitalized. Patient died on 05/16/2006.

Trisenox Side Effects Report #5483251-7
Trisenox side effect was reported by a Physician from JAPAN on Sept 27, 2007. Female patient, 58 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: acute promyelocytic leukaemia differentiation syndrome, alanine aminotransferase increased, blood creatine phosphokinase increased, haemolysis, hepatic function abnormal, hyperglycaemia, renal impairment, retinoic acid syndrome. Trisenox dosage: 8.85 MG QD INTRAVENOUS DRIP. During the same period patient was treated with IDARUBICIN, POTASSIUM SUPPLEMENT, GABEXATE MESILATE, CARPERITIDE, MICAFUNGIN. Patient recovered.

Trisenox Side Effects Report #5320867-2
Trisenox side effect was reported by a Physician from JAPAN on Apr 24, 2007. Female patient, 57 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood bilirubin increased, electrocardiogram qt prolonged, hepatic function abnormal, herpes zoster, white blood cell count decreased. Trisenox dosage: 8.475 MG QD INTRAVENOUS DRIP. During the same period patient was treated with RANITIDINE HYDROCHLORIDE, ALLOPURINOL, PRAVASTATIN, SULFAMETHOXAZOLE AND TRIMETHOPRIM, BROTIZOLAM, ETIZOLAM. Patient was hospitalized. Patient recovered.

Trisenox Side Effects Report #5087025-0
Trisenox side effect was reported by a Physician from JAPAN on Aug 09, 2006. Female patient, 57 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, c-reactive protein increased, headache

, hepatic function abnormal, platelet count decreased, rash

, white blood cell count decreased. Trisenox dosage: 7.77 MG QD INTRAVENOUS DRIP. Patient recovered.

Trisenox Side Effects Report #5127285-0
Trisenox side effect was reported by a Physician from JAPAN on Sept 27, 2006. Female patient, 57 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: electrocardiogram qt prolonged, hepatic function abnormal, white blood cell count decreased. Trisenox dosage: 8.475 MG QD INTRAVENOUS DRIP. During the same period patient was treated with RANITIDINE HYDROCHLORIDE, ALLOPURINOL, PRAVASTATIN. Patient was hospitalized. Patient recovered.

Trisenox Side Effects Report #5147069-7
Trisenox side effect was reported by a Physician from JAPAN on Oct 20, 2006. Female patient, 57 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, electrocardiogram qt prolonged, hepatic function abnormal, herpes zoster, white blood cell count decreased. Trisenox dosage: 8.475 MG QD INTRAVENOUS DRIP. During the same period patient was treated with RANITIDINE HYDROCHLORIDE, ALLOPURINOL, PRAVASTATIN, SULFAMETHOXAZOLE, BROTIZOLAM, ETIZOLAM. Patient was hospitalized. Patient recovered.

Trisenox Side Effects Report #5133972-0
Trisenox side effect was reported by a Physician from JAPAN on Oct 02, 2006. Female patient, 53 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, electrocardiogram qt prolonged, hepatic function abnormal, red blood cell count decreased, white blood cell count decreased. Trisenox dosage: 7.35 MG QD INTRAVENOUS DRIP. Patient recovered.

Trisenox Side Effects Report #5179503-0
Trisenox side effect was reported by a Physician from JAPAN on Nov 29, 2006. Female patient, 53 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, electrocardiogram qt prolonged, haemoglobin decreased, hepatic function abnormal, red blood cell count decreased, white blood cell count decreased. Trisenox dosage: 7.35 MG QD INTRAVENOUS DRIP. Patient recovered.

Trisenox Side Effects Report #5635741-1
Trisenox side effect was reported by a Physician from JAPAN on Feb 05, 2008. Male patient, 53 years of age, was diagnosed with acute promyelocytic leukaemia, convulsion prophylaxis and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, blister, convulsion, electrocardiogram qt prolonged, hepatic function abnormal, herpes zoster, meningitis

, pancytopenia, pseudomonas infection. Trisenox dosage: 10.425 MG,QD,INTRAVENOUS DRIP. During the same period patient was treated with VALPROATE, CYTARABINE, METHOTREXATE, PREDNISOLONE ACETATE, NAFAMOSTATE. Patient was hospitalized. Patient recovered.

Trisenox Side Effects Report #5643136-X
Trisenox side effect was reported by a Physician from JAPAN on Feb 13, 2008. Male patient, 53 years of age, was diagnosed with acute promyelocytic leukaemia, convulsion prophylaxis and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, catheter site infection, central nervous system leukaemia, electrocardiogram qt prolonged, hepatic function abnormal, herpes zoster, meningitis

, pancytopenia, pseudomonas infection. Trisenox dosage: 10.425 MG QD INTRAVENOUS DRIP. During the same period patient was treated with VALPROATE, CYTARABINE, METHOTREXATE, PREDNISOLONE ACETATE, NAFAMOSTATE. Patient was hospitalized. Patient recovered.

Trisenox Side Effects Report #5701451-5
Trisenox side effect was reported by a Health Professional from JAPAN on Mar 24, 2008. Male patient, 53 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, electrocardiogram qt prolonged, hepatic function abnormal, pancytopenia. Trisenox dosage: 10.095 MG QD INTRAVENOUS DRIP. During the same period patient was treated with CYTARABINE, METHOTREXATE, PREDNISOLONE. Patient recovered.

Trisenox Side Effects Report #5320869-6
Trisenox side effect was reported by a Physician from JAPAN on Apr 23, 2007. Male patient, 50 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, csf test abnormal, cytology abnormal, gamma-glutamyltransferase increased, hepatic function abnormal. Trisenox dosage: 9.48 MG QD INTRAVENOUS DRIP. During the same period patient was treated with FLUCONAZOLE, FAMOTIDINE. Patient recovered.

Trisenox Side Effects Report #6088508-7
Trisenox side effect was reported by a Physician from JAPAN on Feb 09, 2009. Male patient, 46 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, blood alkaline phosphatase increased, haemoglobin decreased, hepatic function abnormal, platelet count decreased, white blood cell count decreased. Trisenox dosage: 7.65 MG QD; INTRAVENOUS DRIP. During the same period patient was treated with CYTARABINE, METHOTREXATE, DEXAMETHASONE PHOSPHATE, FILGRASTIM. Patient was hospitalized. Patient recovered.

Trisenox Side Effects Report #6108579-9
Trisenox side effect was reported by a Health Professional from JAPAN on Feb 19, 2009. Male patient, 46 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, blood alkaline phosphatase increased, haemoglobin decreased, hepatic function abnormal, platelet count decreased, white blood cell count decreased. Trisenox dosage: 7.65 MG QD INTRAVENOUS DRIP. During the same period patient was treated with CYTARABINE, METHOTREXATE, DEXAMETHASONE PHOSPHATE, FILGRASTIM. Patient was hospitalized and became disabled. Patient recovered.

Trisenox Side Effects Report #5114873-0
Trisenox side effect was reported by a Physician from JAPAN on Sept 05, 2006. Female patient, 43 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: electrocardiogram qt corrected interval prolonged, electrocardiogram qt prolonged, hepatic function abnormal, white blood cell count decreased. Trisenox dosage: 8.19 MG QD INTRAVENOUS DRIP. During the same period patient was treated with POTASSIUM CHLORIDE, TEPRENONE, MAGNESIUM OXIDE. Patient recovered.

Trisenox Side Effects Report #5913581-3
Trisenox side effect was reported by a Physician from JAPAN on Sept 24, 2008. Female patient, 43 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, electrocardiogram qt prolonged, hepatic function abnormal, hyperglycaemia, ventricular extrasystoles, white blood cell count decreased. Trisenox dosage: 10.2 MG QD INTRAVENOUS DRIP. Patient was hospitalized. Patient recovered.

Trisenox Side Effects Report #5817327-9
Trisenox side effect was reported by a Physician from JAPAN on July 01, 2008. Male patient, 42 years of age, weighting 133.8 lb, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: acute promyelocytic leukaemia differentiation syndrome, alanine aminotransferase increased, blood potassium decreased, blood sodium decreased, hepatic function abnormal, hyperglycaemia, hyperuricaemia, hypoalbuminaemia, hypoproteinaemia. Trisenox dosage: 8.7 MG DAILY; INTRAVENOUS DRIP. During the same period patient was treated with IDARUBICIN HYDROCHLORIDE, LANSOPRAZOLE, ITRACONAZOLE. Patient recovered.

Trisenox Side Effects Report #5102981-X
Trisenox side effect was reported by a Physician from JAPAN on Aug 23, 2006. Male patient, 39 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, electrocardiogram qt corrected interval prolonged, hepatic function abnormal, hypernatraemia, hypokalaemia, white blood cell count decreased. Trisenox dosage: 10.98 MG QD INTRAVENOUS DRIP. During the same period patient was treated with CYTARABINE, METHOTREXATE, DEXAMETHASONE PHOSPHATE, ELECTROLYTE SOLUTION, RANITIDINE HYDROCHLORIDE. Patient recovered.

Trisenox Side Effects Report #5556932-4
Trisenox side effect was reported by a Physician from JAPAN on Nov 26, 2007. Female patient, 38 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase decreased, blood magnesium decreased, blood potassium decreased, electrocardiogram qt prolonged, gamma-glutamyltransferase increased, hepatic function abnormal, oedema, rash

. Trisenox dosage: 8.55 MG QD; INTRAVENOUS DRIP. During the same period patient was treated with GLYCYRRHIZIN, MAGNESIUM REPLACEMENT, POTASSIUM REPLACEMENT, HYDROCORTISONE SUCCINATE, PREDNISOLONE, SPIRONOLACTONE, FUROSEMIDE. Patient recovered.

Trisenox Side Effects Report #5635799-X
Trisenox side effect was reported by a Physician from JAPAN on Feb 07, 2008. Female patient, 38 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood magnesium decreased, blood potassium decreased, electrocardiogram qt prolonged, gamma-glutamyltransferase increased, hepatic function abnormal, oedema, rash

. Trisenox dosage: 8.55 MG QD INTRAVENOUS DRIP. During the same period patient was treated with GLYCYRRHIZIN, MAGNESIUM REPLACEMENT, POTASSIUM REPLACEMENT, HYDROCORTISONE SUCCINATE, PREDNISOLONE, SPIRONOLACTONE, FUROSEMIDE. Patient recovered.

Trisenox Side Effects Report #5260932-1
Trisenox side effect was reported by a Physician from JAPAN on Feb 20, 2007. Female patient, 32 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood lactate dehydrogenase decreased, blood urea decreased, electrocardiogram qt corrected interval prolonged, hepatic function abnormal, protein total decreased, rash

, white blood cell count decreased. Trisenox dosage: 7.05 MG QD INTRAVENOUS DRIP. During the same period patient was treated with ELECTROLYTE. Patient was hospitalized. Patient recovered.

Trisenox Side Effects Report #5397292-1
Trisenox side effect was reported by a Physician from JAPAN on July 05, 2007. Female patient, 32 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, c-reactive protein increased, electrocardiogram qt prolonged, hepatic function abnormal, hypocalcaemia, pancytopenia. Trisenox dosage: 9.15 MG QD INTRAVENOUS DRIP. During the same period patient was treated with FEXOFENADINE HYDROCHLORIDE, RANITIDINE HYDROCHLORIDE, GEFARNATE, ETIZOLAM, ZOLPIDEM TARTRATE. Patient recovered.

Trisenox Side Effects Report #5580740-1
Trisenox side effect was reported by a Physician from JAPAN on Dec 06, 2007. Male patient, 28 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood lactate dehydrogenase increased, c-reactive protein increased, electrocardiogram qt prolonged, gamma-glutamyltransferase increased, haemoglobin decreased, hepatic function abnormal, tonsillitis. Trisenox dosage: 12 MG QD INTRAVENOUS DRIP. During the same period patient was treated with DALTEPARIN, SULFAMETHOXAZOLE AND TRIMETHOPRIM, FLUCONAZOLE, OMEPRAZOLE, ROXATIDINE ACETATE, FAMOTIDINE. Patient was hospitalized. Patient recovered.

Trisenox Side Effects Report #5497267-8
Trisenox side effect was reported by a Physician from JAPAN on Oct 10, 2007. Female patient, 27 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: acute promyelocytic leukaemia differentiation syndrome, alanine aminotransferase increased, aspartate aminotransferase increased, electrocardiogram qt prolonged, haemoglobin decreased, hepatic function abnormal, hypokalaemia, leukocytosis, platelet count decreased. Trisenox dosage: 7.8 MG QD INTRAVENOUS DRIP. During the same period patient was treated with ELECTROLYTE, IDARUBICIN, PANIPENEM, AMIKACIN SULPHATE, MICAFUNGIN, ABREKACIN SULPHATE, MEROPENEM HYDRATE. Patient recovered.

Trisenox Side Effects Report #5525457-4
Trisenox side effect was reported by a Physician from JAPAN on Nov 05, 2007. Female patient, 27 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: acute promyelocytic leukaemia differentiation syndrome, alanine aminotransferase increased, aspartate aminotransferase increased, electrocardiogram qt prolonged, haemoglobin decreased, hepatic function abnormal, hypokalaemia, leukocytosis, platelet count decreased. Trisenox dosage: 7.8 MG QD INTRAVENOUS DRIP. During the same period patient was treated with IDARUBICIN, PANIPENEM, AMIKACIN SULPHATE, MICAFUNGIN, ARBEKACIN SULPHATE, MEROPENEM HYDRATE. Patient recovered.

Trisenox Side Effects Report #6025183-1
Trisenox side effect was reported by a Health Professional from JAPAN on Dec 17, 2008. Female patient, 17 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, hepatic function abnormal. Trisenox dosage: 7.05 MG DAILY; INTRAVENOUS DRIP. Patient recovered.

Trisenox Side Effects Report #5424427-4
Trisenox side effect was reported by a Physician from JAPAN on Aug 09, 2007. Female patient was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: blood creatine phosphokinase increased, blood creatinine increased, hepatic function abnormal. Trisenox dosage: unknown. Patient recovered.

Trisenox Side Effects Report #5430947-9
Trisenox side effect was reported by a Physician from JAPAN on Aug 28, 2007. Female patient was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: blood creatine phosphokinase increased, blood creatinine increased, haemolysis, hepatic function abnormal. Trisenox dosage: unknown. Patient recovered.

Trisenox Side Effects Report #5507315-4
Trisenox side effect was reported by a Physician from JAPAN on Oct 22, 2007. Female patient was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, electrocardiogram qt prolonged, gamma-glutamyltransferase increased, hepatic function abnormal, oedema, rash

, weight increased. Trisenox dosage: 8.55 MG QD INTRAVENOUS DRIP. During the same period patient was treated with HYDROCORTISONE SUCCINATE, PREDNISOLONE, SPIRONOLACTONE, FUROSEMIDE. Patient recovered.

Trisenox Side Effects Report #4599944-X
Trisenox side effect was reported by a Physician from on Feb 14, 2005. Female patient was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: hepatic function abnormal, transaminases increased. Trisenox dosage: unknown. Patient recovered.

Trisenox Side Effects Report #5912529-5
Trisenox side effect was reported by a Physician from JAPAN on Aug 22, 2008. Male patient, 83 years of age, was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, altered state of consciousness, aspartate aminotransferase increased, asterixis, dialysis

, hepatic function abnormal, tubulointerstitial nephritis. Trisenox dosage: unknown. Patient recovered.

Trisenox Side Effects Report #5588255-1
Trisenox side effect was reported by a Physician from JAPAN on Dec 26, 2007. Female patient was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, electrocardiogram qt prolonged, enteritis, hepatic function abnormal, pancytopenia. Trisenox dosage: unknown. Patient recovered.

Trisenox and hepatic function abnormal

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Trisenox and hepatic function abnormal Patient Reports March 16, 2010

side effects of Trisenox