Trisenox and ventricular extrasystoles Patient Reports February 10, 2010

Trisenox Side Effects Report #5564264-3
Trisenox side effect was reported by a Physician from JAPAN on Nov 30, 2007. Female patient, 87 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: neutropenia, ventricular extrasystoles. Trisenox dosage: 6.21 MG QD INTRAVENOUS DRIP. During the same period patient was treated with SULFAMETHOXAZOLE AND TRIMETHOPRIM. Patient was hospitalized. Patient recovered.

Trisenox Side Effects Report #5401991-2
Trisenox side effect was reported by a Physician from JAPAN on July 17, 2007. Female patient, 86 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: arrhythmia , haemoglobin decreased, hypocalcaemia, neutrophil count decreased, ventricular extrasystoles. Trisenox dosage: 6.105 MG QD INTRAVENOUS DRIP. During the same period patient was treated with CYTARABINE, PREDNISOLONE ACETATE, METHOTREXATE, CALCIUM GLUCONATE. Patient was hospitalized. Patient recovered.

Trisenox Side Effects Report #4615938-X
Trisenox side effect was reported by a Physician from on Feb 28, 2005. Female patient, 83 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: pancytopenia, ventricular extrasystoles. Trisenox dosage: 0.15 MG/KG, QD (5X/WK)), IVI. During the same period patient was treated with MEXILETINE. Patient was hospitalized. Patient recovered.

Trisenox Side Effects Report #4644261-2
Trisenox side effect was reported by a Physician from on Feb 28, 2005. Female patient, 83 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: anaemia, pancytopenia, ventricular extrasystoles. Trisenox dosage: 0.15 MG/KG, QD. During the same period patient was treated with MEXILETINE. Patient was hospitalized. Patient recovered.


Trisenox Side Effects Report #5201251-9
Trisenox side effect was reported by a Physician from JAPAN on Dec 20, 2006. Male patient, 70 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: electrocardiogram qt corrected interval prolonged, ventricular extrasystoles, ventricular tachycardia. Trisenox dosage: 77.8 MG QD INTRAVENOUS DRIP. During the same period patient was treated with TRETINOIN, HYDROXYCARBAMIDE, NAFAMOSTAT MESILATE, CEFMETAZOLE, SPIRONOLACTONE. Patient recovered.

Trisenox Side Effects Report #5187992-0
Trisenox side effect was reported by a Physician from JAPAN on Nov 30, 2006. Male patient, 70 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: ventricular extrasystoles, ventricular tachycardia. Trisenox dosage: 7.8 MG QD INTRAVENOUS DRIP. During the same period patient was treated with TRETINOIN, HYDROXYCARBAMIDE, NAFAMOSTAT MESILATE, CEFMETAZOLE, SPIRONOLACTONE. Patient recovered.

Trisenox Side Effects Report #4712344-4
Trisenox side effect was reported by a Physician from JAPAN on June 20, 2005. Male patient, 67 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, chest x-ray abnormal, dyspnoea exacerbated, electrocardiogram qt corrected interval prolonged, lung injury, ventricular extrasystoles, white blood cell count increased. Trisenox dosage: 8 MG (8 MG,), IVI. Patient was hospitalized. Patient recovered.

Trisenox Side Effects Report #5913581-3
Trisenox side effect was reported by a Physician from JAPAN on Sept 24, 2008. Female patient, 43 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, electrocardiogram qt prolonged, hepatic function abnormal, hyperglycaemia, ventricular extrasystoles, white blood cell count decreased. Trisenox dosage: 10.2 MG QD INTRAVENOUS DRIP. Patient was hospitalized. Patient recovered.

Trisenox Side Effects Report #4801568-3
Trisenox side effect was reported by a Physician from JAPAN on Sept 29, 2005. Female patient, 41 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: electrocardiogram qt corrected interval prolonged, electrocardiogram qt prolonged, ventricular extrasystoles. Trisenox dosage: 8.7 MG QD INTRAVENOUS DRIP. Patient recovered.


Trisenox Side Effects Report #4806740-4
Trisenox side effect was reported by a Physician from JAPAN on Oct 12, 2005. Female patient, 41 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: electrocardiogram qt corrected interval prolonged, electrocardiogram qt prolonged, ventricular extrasystoles. Trisenox dosage: 8.7 MG QD INTRAVENOUS DRIP. Patient recovered.

Trisenox Side Effects Report #5698243-2
Trisenox side effect was reported by a Physician from JAPAN on Mar 21, 2008. Male patient, 34 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, ventricular extrasystoles. Trisenox dosage: 12 MG QD; INTRAVENOUS DRIP. Patient was hospitalized. Patient recovered.

Trisenox Side Effects Report #5223699-9
Trisenox side effect was reported by a Physician from JAPAN on Jan 12, 2007. Female patient, 27 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: electrocardiogram qt prolonged, ventricular extrasystoles. Trisenox dosage: unknown. Patient recovered.

Trisenox Side Effects Report #5175212-2
Trisenox side effect was reported by a Physician from JAPAN on Nov 22, 2006. Female patient, 27 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: ventricular extrasystoles. Trisenox dosage: unknown. Patient recovered.

Trisenox Side Effects Report #5201330-6
Trisenox side effect was reported by a Physician from JAPAN on Dec 19, 2006. Female patient, 20 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: chest discomfort, torsade de pointes, ventricular extrasystoles. Trisenox dosage: 0.15 MG/KG QD INTRAVENOUS. During the same period patient was treated with FLUCONAZOLE. Patient recovered.


Trisenox Side Effects Report #5444034-7
Trisenox side effect was reported by a Physician from UNITED STATES on Aug 23, 2007. Male patient, 59 years of age, weighting 176.4 lb, was diagnosed with acute myeloid leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: blood potassium increased, blood pressure decreased, dialysis , tachycardia, ventricular extrasystoles. Trisenox dosage: 0.15, MG/KG INTRAVENOUS DRIP. During the same period patient was treated with INTERFERON, DEXAMETHASONE. Patient recovered.

Trisenox Side Effects Report #5486497-7
Trisenox side effect was reported by a Physician from UNITED STATES on Oct 02, 2007. Male patient, 59 years of age, was diagnosed with acute myeloid leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: blood potassium increased, blood pressure decreased, dialysis , electrocardiogram qrs complex prolonged, electrocardiogram qt prolonged, electrocardiogram st segment elevation, tachycardia, ventricular extrasystoles. Trisenox dosage: 0.15 MG/KG ONCE INTRAVENOUS DRIP. During the same period patient was treated with INTERFERON, DEXAMETHASONE. Patient was hospitalized. Patient recovered.