Valproic and alanine aminotransferase increased Patient Reports February 10, 2010

Valproic Side Effects Report #4999393-6
Valproic side effect was reported by a Pharmacist from UNITED STATES on May 09, 2006. Female patient, 33 years of age, was diagnosed with schizophrenia and was treated with Valproic. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, ammonia increased, aspartate aminotransferase increased, blood bilirubin increased, dizziness , hepatotoxicity, lethargy, liver function test abnormal. Valproic dosage: 250MG TID PO. Patient was hospitalized. Patient recovered.

Valproic Side Effects Report #4590988-0
Valproic side effect was reported by a Pharmacist from on Feb 22, 2005. Male patient, 44 years of age, was diagnosed with psychotic disorder  and was treated with Valproic. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased. Valproic dosage: unknown. During the same period patient was treated with CLOZAPINE. Patient was hospitalized. Patient recovered.

Valproic Side Effects Report #5255898-4
Valproic side effect was reported by a Consumer or non-health professional from FRANCE on Feb 23, 2007. Male patient, 18 years of age, was diagnosed with neonatal asphyxia and was treated with Valproic. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, ammonia increased, aspartate aminotransferase increased, gamma-glutamyltransferase increased, hepatotoxicity, rhabdomyolysis. Valproic dosage: unknown. During the same period patient was treated with PHENOBARBITAL. Patient recovered.

Valproic Side Effects Report #5255904-7
Valproic side effect was reported by a Consumer or non-health professional from FRANCE on Feb 23, 2007. Female patient, 17 years of age, was diagnosed with myoclonic epilepsy and was treated with Valproic. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, gamma-glutamyltransferase increased, hepatotoxicity, jaundice . Valproic dosage: unknown. Patient recovered.


Valproic Side Effects Report #5255908-4
Valproic side effect was reported by a Consumer or non-health professional from FRANCE on Feb 23, 2007. Female patient, child 7. years of age, was diagnosed with hydrocephalus  and was treated with Valproic. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, gamma-glutamyltransferase increased, hepatotoxicity, renal failure. Valproic dosage: unknown. During the same period patient was treated with ETHOSUXIMIDE, VIGABATRIN. Patient recovered.

Valproic Side Effects Report #5255900-X
Valproic side effect was reported by a Consumer or non-health professional from FRANCE on Feb 23, 2007. Female patient, child 10 years of age, was diagnosed with fragile x syndrome  and was treated with Valproic. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, ammonia increased, aspartate aminotransferase increased, gamma-glutamyltransferase increased, hepatic encephalopathy, hepatotoxicity, renal failure. Valproic dosage: unknown. During the same period patient was treated with TOPIRAMATE. Patient recovered.

Valproic Side Effects Report #5635462-5
Valproic side effect was reported by a Consumer or non-health professional from FRANCE on Feb 14, 2008. Female patient, 62 years of age, was diagnosed with epilepsy , chronic obstructive pulmonary disease and was treated with Valproic. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood bilirubin increased, blood lactate dehydrogenase increased, depressed level of consciousness, hyperammonaemia, metabolic encephalopathy, supraventricular tachycardia. Valproic dosage: unknown. During the same period patient was treated with SOTALOL, BACLOFEN, PAROXETINE, LACTULOSE, ASPIRIN, OMEPRAZOLE, PREDNISONE. Patient was hospitalized and became disabled. Patient recovered.

Valproic Side Effects Report #5635524-2
Valproic side effect was reported by a Consumer or non-health professional from FRANCE on Feb 14, 2008. Female patient, 62 years of age, was diagnosed with epilepsy , chronic obstructive pulmonary disease and was treated with Valproic. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood bilirubin increased, blood lactate dehydrogenase increased, depressed level of consciousness, hyperammonaemia, metabolic encephalopathy, supraventricular tachycardia. Valproic dosage: unknown. During the same period patient was treated with SOTALOL, BACLOFEN, PAROXETINE, LACTULOSE, ASPIRIN, OMEPRAZOLE, PREDNISONE. Patient was hospitalized and became disabled. Patient recovered.

Valproic Side Effects Report #5767672-0
Valproic side effect was reported by a Consumer or non-health professional from FRANCE on June 04, 2008. Female patient, 62 years of age, was diagnosed with epilepsy , chronic obstructive pulmonary disease and was treated with Valproic. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood bilirubin increased, blood lactate dehydrogenase increased, depressed level of consciousness, hyperammonaemia, metabolic encephalopathy, supraventricular tachycardia. Valproic dosage: unknown. During the same period patient was treated with SOTALOL, BACLOFEN, PAROXETINE, LACTULOSE, ASPIRIN, OMEPRAZOLE, PREDNISONE. Patient was hospitalized and became disabled. Patient recovered.


Valproic Side Effects Report #5255903-5
Valproic side effect was reported by a Consumer or non-health professional from FRANCE on Feb 23, 2007. Female patient, 25 years of age, was diagnosed with epilepsy  and was treated with Valproic. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, ammonia increased, aspartate aminotransferase increased, cerebral infarction, gamma-glutamyltransferase increased, hepatotoxicity, rhabdomyolysis. Valproic dosage: unknown. Patient recovered.

Valproic Side Effects Report #5038437-2
Valproic side effect was reported by a Pharmacist from UNITED STATES on June 26, 2006. Female patient, 83 years of age, was diagnosed with convulsion and was treated with Valproic. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, liver function test abnormal. Valproic dosage: 250 MG BID NASAL. Patient was hospitalized. Patient recovered.

Valproic Side Effects Report #5255909-6
Valproic side effect was reported by a Consumer or non-health professional from FRANCE on Feb 23, 2007. Female patient, child 4 years of age, was diagnosed with amaurotic familial idiocy and was treated with Valproic. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, ammonia increased, aspartate aminotransferase increased, hepatotoxicity, jaundice . Valproic dosage: unknown. During the same period patient was treated with ETHOSUXIMIDE. Patient recovered.

Valproic Side Effects Report #4700732-1
Valproic side effect was reported by a Consumer or non-health professional from on June 21, 2005. Female patient, 57 years of age, was treated with Valproic. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood creatinine increased, blood urea increased, eosinophil count increased, erythema multiforme, lymphadenopathy, lymphocyte morphology abnormal, pyrexia. Valproic dosage: unknown. Patient was hospitalized. Patient recovered.

Valproic Side Effects Report #6063687-6
Valproic side effect was reported by a Physician from UNITED STATES on Jan 06, 2009. Female patient, 43 years of age, was treated with Valproic. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, alanine aminotransferase increased, aspartate aminotransferase increased, blood bicarbonate decreased, blood creatine phosphokinase increased, blood glucose increased, blood ph decreased, blood pressure decreased, blood urea increased. Valproic dosage: unknown. During the same period patient was treated with FLURAZEPAM, BUPROPION, TEMAZEPAM. Patient died.


Valproic Side Effects Report #5866702-5
Valproic side effect was reported by a Consumer or non-health professional from UNITED STATES on Aug 28, 2008. Male patient, 37 years of age, weighting 220.5 lb, was treated with Valproic. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased. Valproic dosage: 1750 MG DAILY PO. Patient recovered.

Valproic Side Effects Report #5122204-5
Valproic side effect was reported by a Consumer or non-health professional from FRANCE on July 12, 2006. Female patient, 23 years of age, was treated with Valproic. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, apathy, aspartate aminotransferase increased, bilirubin conjugated increased, blood alkaline phosphatase increased, blood bilirubin increased, confusional state, decreased activity, depressed level of consciousness. Valproic dosage: unknown. During the same period patient was treated with VALPROIC ACID, CLOZAPINE. Patient was hospitalized. Patient died.

Valproic Side Effects Report #5928790-7
Valproic side effect was reported by a Health Professional from ALBANIA on Oct 20, 2008. Male patient was diagnosed with epilepsy  and was treated with Valproic. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, coma, confusional state, convulsion, hyperammonaemia, hypoglycaemia, reye's syndrome, vomiting. Valproic dosage: 30 MG/KG, UNK. During the same period patient was treated with PHENOBARBITAL. Patient was hospitalized. Patient recovered.