Vincristine and reversible posterior leukoencephalopathy syndrome Patient Reports February 10, 2010

Vincristine Side Effects Report #5950468-4
Vincristine side effect was reported by a Health Professional from ITALY on Nov 10, 2008. Male patient, child 4 years of age, was diagnosed with t-cell type acute leukaemia and was treated with Vincristine. After drug was administered, patient experienced the following side effects: reversible posterior leukoencephalopathy syndrome. Vincristine dosage: unknown. During the same period patient was treated with DOXORUBICIN, DEXAMETHASONE, ASPARAGINASE. Patient recovered.

Vincristine Side Effects Report #4622825-X
Vincristine side effect was reported by a Pharmacist from on Mar 28, 2005. Female patient, 68 years of age, was diagnosed with non-small cell lung cancer and was treated with Vincristine. After drug was administered, patient experienced the following side effects: reversible posterior leukoencephalopathy syndrome. Vincristine dosage: 1.4 MG/M2. During the same period patient was treated with ASPIRIN, PLAVIX, PREMARIN, ATENOLOL, POTASSIUM CHLORIDE, HYDROCHLOROTHIAZIDE, LEVOTHYROXINE, ALLOPURINOL. Patient recovered.

Vincristine Side Effects Report #5849007-8
Vincristine side effect was reported by a Physician from TURKEY on Aug 07, 2008. Male patient, 14 years of age, was diagnosed with non-hodgkin's lymphoma and was treated with Vincristine. After drug was administered, patient experienced the following side effects: reversible posterior leukoencephalopathy syndrome. Vincristine dosage: unknown. During the same period patient was treated with CYCLOPHOSPHAMIDE, DOXORUBICIN, PREDNISONE. Patient recovered.

Vincristine Side Effects Report #5849120-5
Vincristine side effect was reported by a Pharmacist from TURKEY on Aug 07, 2008. Female patient, child 11 years of age, was diagnosed with non-hodgkin's lymphoma and was treated with Vincristine. After drug was administered, patient experienced the following side effects: reversible posterior leukoencephalopathy syndrome. Vincristine dosage: unknown. During the same period patient was treated with CYCLOPHOSPHAMIDE, DOXORUBICIN, PREDNISOLONE. Patient recovered.


Vincristine Side Effects Report #5787978-9
Vincristine side effect was reported by a Health Professional from INDIA on June 23, 2008. Male patient, child 9 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with Vincristine. After drug was administered, patient experienced the following side effects: febrile neutropenia, ileus paralytic, reversible posterior leukoencephalopathy syndrome, tumour lysis syndrome. Vincristine dosage: unknown. During the same period patient was treated with PREDNISONE, DAUNORUBICIN, ASPARAGINASE. Patient recovered.

Vincristine Side Effects Report #5795211-7
Vincristine side effect was reported by a Health Professional from INDIA on June 26, 2008. Male patient, child 9 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with Vincristine. After drug was administered, patient experienced the following side effects: febrile neutropenia, grand mal convulsion, ileus paralytic, paraesthesia, renal impairment, reversible posterior leukoencephalopathy syndrome, tumour lysis syndrome, visual disturbance. Vincristine dosage: unknown. During the same period patient was treated with PREDNISONE, DAUNORUBICIN, ASPARAGINASE, METHOTREXATE. Patient recovered.

Vincristine Side Effects Report #5948252-0
Vincristine side effect was reported by a Consumer or non-health professional from ITALY on Nov 03, 2008. Female patient, child 5 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with Vincristine. After drug was administered, patient experienced the following side effects: reversible posterior leukoencephalopathy syndrome. Vincristine dosage: unknown. During the same period patient was treated with DEXAMETHASONE, ASPARAGINASE, DOXORUBICIN. Patient recovered.

Vincristine Side Effects Report #5950469-6
Vincristine side effect was reported by a Health Professional from ITALY on Nov 10, 2008. Female patient, child 5 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with Vincristine. After drug was administered, patient experienced the following side effects: reversible posterior leukoencephalopathy syndrome, temporal lobe epilepsy. Vincristine dosage: unknown. During the same period patient was treated with DOXORUBICIN, DEXAMETHASONE, ASPARAGINASE. Patient recovered.

Vincristine Side Effects Report #5484990-4
Vincristine side effect was reported by a Health Professional from UNITED STATES on Sept 26, 2007. Female patient, child 4 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with Vincristine. After drug was administered, patient experienced the following side effects: brain oedema, convulsion, hypertension, loss of consciousness, nuclear magnetic resonance imaging abnormal, reversible posterior leukoencephalopathy syndrome. Vincristine dosage: unknown. During the same period patient was treated with METHOTREXATE, DAUNORUBICIN HYDROCHLORIDE, ASPARAGINASE. Patient was hospitalized. Patient recovered.


Vincristine Side Effects Report #5948251-9
Vincristine side effect was reported by a Consumer or non-health professional from ITALY on Nov 03, 2008. Male patient, child 4 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with Vincristine. After drug was administered, patient experienced the following side effects: reversible posterior leukoencephalopathy syndrome. Vincristine dosage: unknown. During the same period patient was treated with DEXAMETHASONE, ASPARAGINASE, DOXORUBICIN. Patient recovered.

Vincristine Side Effects Report #5484991-6
Vincristine side effect was reported by a Health Professional from UNITED STATES on Sept 26, 2007. Male patient, 13 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with Vincristine. After drug was administered, patient experienced the following side effects: blood pressure increased, brain oedema, grand mal convulsion, reversible posterior leukoencephalopathy syndrome. Vincristine dosage: unknown. During the same period patient was treated with ASPARAGINASE, DAUNORUBICIN, METHOTREXATE, PREDNISONE. Patient recovered.

Vincristine Side Effects Report #5789609-0
Vincristine side effect was reported by a Health Professional from INDIA on June 23, 2008. Female patient, child 11 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with Vincristine. After drug was administered, patient experienced the following side effects: febrile neutropenia, ileus paralytic, reversible posterior leukoencephalopathy syndrome. Vincristine dosage: unknown. During the same period patient was treated with METHOTREXATE, PREDNISONE, DAUNORUBICIN, ASPARAGINASE. Patient recovered.

Vincristine Side Effects Report #5795222-1
Vincristine side effect was reported by a Health Professional from INDIA on June 26, 2008. Female patient, child 11 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with Vincristine. After drug was administered, patient experienced the following side effects: febrile neutropenia, ileus paralytic, reversible posterior leukoencephalopathy syndrome. Vincristine dosage: unknown. During the same period patient was treated with METHOTREXATE, PREDNISONE, DAUNORUBICIN, ASPARAGINASE. Patient recovered.

Vincristine Side Effects Report #5319713-2
Vincristine side effect was reported by a Consumer or non-health professional from SWITZERLAND on Apr 20, 2007. Female patient, 62 years of age, was treated with Vincristine. After drug was administered, patient experienced the following side effects: cerebral disorder, cerebrovascular disorder, convulsion, endothelial dysfunction, reversible posterior leukoencephalopathy syndrome, sopor. Vincristine dosage: unknown. During the same period patient was treated with RITUXIMAB, CYCLOPHOSPHAMIDE, DOXORUBICIN, PREDNISONE. Patient was hospitalized. Patient recovered.


Vincristine Side Effects Report #5756720-X
Vincristine side effect was reported by a Health Professional from FRANCE on May 23, 2008. Female patient was treated with Vincristine. After drug was administered, patient experienced the following side effects: coordination abnormal, dyskinesia, fall , reversible posterior leukoencephalopathy syndrome. Vincristine dosage: UNIT DOSE: 1 GR/ML. During the same period patient was treated with METHOTREXATE, CYCLOPHOSPHAMIDE, CYTARABINE, DAUNORUBICIN, ASPARAGINASE, METHYLPREDNISOLONE ACETATE. Patient was hospitalized. Patient recovered.