Zyvox and multi-organ failure Patient Reports February 09, 2010

Zyvox Side Effects Report #5243100-9
Zyvox side effect was reported by a Consumer or non-health professional from KOREA, REPUBLIC OF on Feb 13, 2007. Female patient, weighting 132.3 lb, was diagnosed with staphylococcal sepsis, urinary tract infection  and was treated with Zyvox. After drug was administered, patient experienced the following side effects: multi-organ failure, septic shock. Zyvox dosage: unknown. During the same period patient was treated with TAZOCIN, HYDROCORTISONE, NOREPINEPHRINE BITARTRATE. Patient died on 10/28/2006.

Zyvox Side Effects Report #5024543-5
Zyvox side effect was reported by a Physician from JAPAN on May 24, 2006. Male patient, 90 years of age, was diagnosed with staphylococcal infection  and was treated with Zyvox. After drug was administered, patient experienced the following side effects: metabolic acidosis, multi-organ failure, nausea . Zyvox dosage: 1200 MG , ORAL. During the same period patient was treated with VANCOMYCIN, TEICOPLANIN. Patient died on 05/23/2006.

Zyvox Side Effects Report #5102657-9
Zyvox side effect was reported by a Physician from JAPAN on Aug 25, 2006. Female patient, 78 years of age, weighting 84.88 lb, was diagnosed with staphylococcal infection  and was treated with Zyvox. After drug was administered, patient experienced the following side effects: anaemia, condition aggravated, multi-organ failure, nephrogenic anaemia, platelet count decreased, respiratory disorder, wound . Zyvox dosage: 600 MG (600 MG,1 IN 1 D),INTRAVENOUS. During the same period patient was treated with MEROPEN, LIPLE. Patient was hospitalized. Patient died on 07/31/2006.

Zyvox Side Effects Report #5037067-6
Zyvox side effect was reported by a Physician from JAPAN on June 08, 2006. Male patient, 74 years of age, was diagnosed with staphylococcal infection  and was treated with Zyvox. After drug was administered, patient experienced the following side effects: dyspnoea, haemoglobin increased, international normalised ratio increased, metabolic acidosis, multi-organ failure, platelet count decreased, prothrombin time prolonged. Zyvox dosage: 1200 MG, ORAL. During the same period patient was treated with WARFARIN, DOGMATYL, MUCOSTA, VITAMEDIN CAPSULE, FAMOTIDINE. Patient died on 09/10/2004.


Zyvox Side Effects Report #5045507-1
Zyvox side effect was reported by a Physician from JAPAN on June 20, 2006. Male patient, 73 years of age, weighting 72.53 lb, was diagnosed with staphylococcal infection  and was treated with Zyvox. After drug was administered, patient experienced the following side effects: anorexia, cardiac valve replacement complication, dyspnoea, international normalised ratio increased, metabolic acidosis, multi-organ failure, platelet count decreased, pyrexia, staphylococcal infection . Zyvox dosage: unknown. During the same period patient was treated with WARFARIN, DOGMATYL, MUCOSTA, VITAMEDIN CAPSULE, FAMOTIDINE, POSTERISANTE. Patient died on 09/10/2004.

Zyvox Side Effects Report #5070365-9
Zyvox side effect was reported by a Physician from JAPAN on July 19, 2006. Female patient, 49 years of age, was diagnosed with staphylococcal infection  and was treated with Zyvox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood alkaline phosphatase increased, blood bilirubin increased, gamma-glutamyltransferase increased, multi-organ failure. Zyvox dosage: 1200 MG, INTRAVENOUS. Patient died on 07/12/2006.

Zyvox Side Effects Report #5282189-8
Zyvox side effect was reported by a Physician from JAPAN on Mar 19, 2007. Male patient, weighting 138.9 lb, was diagnosed with staphylococcal infection  and was treated with Zyvox. After drug was administered, patient experienced the following side effects: acidosis, depressed level of consciousness, hypoglycaemia, multi-organ failure. Zyvox dosage: unknown. During the same period patient was treated with LEVOFLOXACIN, VANCOMYCIN HYDROCHLORIDE, TIENAM, THEOLONG, ASPIRIN, TAKEPRON, ALLOPURINOL, MUCOSOLVAN. Patient was hospitalized. Patient died on 03/03/2007.

Zyvox Side Effects Report #5307650-9
Zyvox side effect was reported by a Physician from JAPAN on Apr 13, 2007. Male patient, weighting 138.9 lb, was diagnosed with staphylococcal infection , bacterial infection  and was treated with Zyvox. After drug was administered, patient experienced the following side effects: acidosis, depressed level of consciousness, hypoglycaemia, multi-organ failure. Zyvox dosage: unknown. During the same period patient was treated with LEVOFLOXACIN, VANCOMYCIN, TIENAM, THEOLONG, ASPIRIN, TAKEPRON, ALLOPURINOL, MUCOSOLVAN. Patient was hospitalized. Patient died on 03/03/2007.

Zyvox Side Effects Report #5350724-7
Zyvox side effect was reported by a Pharmacist from UNITED STATES on June 06, 2007. Male patient was diagnosed with staphylococcal infection  and was treated with Zyvox. After drug was administered, patient experienced the following side effects: epistaxis, haematocrit decreased, multi-organ failure, oral intake reduced, renal impairment, thrombocytopenia. Zyvox dosage: 600 MG BID PO. Patient recovered.


Zyvox Side Effects Report #5695103-8
Zyvox side effect was reported by a Pharmacist from JAPAN on Mar 24, 2008. Male patient, weighting 110.2 lb, was diagnosed with staphylococcal infection  and was treated with Zyvox. After drug was administered, patient experienced the following side effects: gastric perforation, multi-organ failure, platelet count decreased, white blood cell count decreased. Zyvox dosage: unknown. During the same period patient was treated with DALACIN S, AMBISOME, OMEPRAL, STRONG NEO MINOPHAGEN C, VANCOMYCIN HYDROCHLORIDE, HICALIQ, AMINOLEBAN, ELEMENMIC. Patient died on 03/13/2008.

Zyvox Side Effects Report #5713389-8
Zyvox side effect was reported by a Consumer or non-health professional from JAPAN on Apr 10, 2008. Male patient, weighting 110.2 lb, was diagnosed with staphylococcal infection  and was treated with Zyvox. After drug was administered, patient experienced the following side effects: multi-organ failure, septic shock. Zyvox dosage: unknown. During the same period patient was treated with TARGOCID, DALACIN, PAZUCROSS. Patient died on 10/06/2007.

Zyvox Side Effects Report #5440960-3
Zyvox side effect was reported by a Health Professional from FRANCE on Aug 21, 2007. Female patient, weighting 154.3 lb, was diagnosed with sepsis , staphylococcal infection , depression , back pain , pulmonary oedema, hypertension and was treated with Zyvox. After drug was administered, patient experienced the following side effects: coma, convulsion, fall , haemodynamic instability, hypertension, multi-organ failure, pneumonia , renal failure. Zyvox dosage: DAILY DOSE:1200MG. During the same period patient was treated with PAROXETINE, TRAMADOL HYDROCHLORIDE AND ACETAMINOPHEN, LASIX, LOXEN, VANCOMYCIN HYDROCHLORIDE. Patient was hospitalized. Patient recovered.

Zyvox Side Effects Report #4838269-1
Zyvox side effect was reported by a Physician from GERMANY on Nov 11, 2005. Male patient, weighting 213.8 lb, was diagnosed with sepsis  and was treated with Zyvox. After drug was administered, patient experienced the following side effects: leukopenia, multi-organ failure, septic shock, thrombocytopenia. Zyvox dosage: 600 MG (600 MG, DAILY), INTRAVENOUS. During the same period patient was treated with NOREPIN, PACKED RED CELLS, HEPARIN, INSULIN, VERAPAMIL, KATAMINE, PROPOFOL, AMIODARONE. Patient died on 10/06/2005.

Zyvox Side Effects Report #5056220-9
Zyvox side effect was reported by a Physician from JAPAN on July 03, 2006. Female patient, 70 years of age, weighting 99.21 lb, was diagnosed with pneumonia staphylococcal and was treated with Zyvox. After drug was administered, patient experienced the following side effects: anuria, fluid intake reduced, haemodialysis, multi-organ failure, platelet count decreased, stenotrophomonas infection. Zyvox dosage: unknown. During the same period patient was treated with TIENAM, PRODIF, ELASPOL, MEDROL ACETATE, FIRSTCIN, CYCLOPHOSPHAMIDE. Patient was hospitalized. Patient died on 06/19/2006.


Zyvox Side Effects Report #5061267-2
Zyvox side effect was reported by a Physician from JAPAN on July 07, 2006. Female patient, 70 years of age, weighting 99.21 lb, was diagnosed with pneumonia staphylococcal and was treated with Zyvox. After drug was administered, patient experienced the following side effects: acute respiratory failure, anuria, haemodialysis, multi-organ failure, platelet count decreased, stenotrophomonas infection. Zyvox dosage: unknown. During the same period patient was treated with TIENAM, PRODIF, ELASPOL, MEDROL ACETATE, FIRSTCIN, CYCLOPHOSPHAMIDE. Patient was hospitalized. Patient died on 06/19/2006.

Zyvox Side Effects Report #5267690-5
Zyvox side effect was reported by a Consumer or non-health professional from JAPAN on Mar 06, 2007. Male patient, weighting 110.2 lb, was diagnosed with pneumonia staphylococcal and was treated with Zyvox. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, hepatic enzyme increased, multi-organ failure, platelet count decreased. Zyvox dosage: unknown. During the same period patient was treated with MINOCYCLINE, MEROPEN, PAZUFLOXACIN MESILATE, VANCOMYCIN, FLUCONAZOLE, MICAFUNGIN, AMIKACIN SULPHATE, MAXIPIME. Patient was hospitalized and became disabled. Patient died on 09/16/2005.

Zyvox Side Effects Report #5194265-9
Zyvox side effect was reported by a Consumer or non-health professional from JAPAN on Oct 03, 2006. Male patient, weighting 110.2 lb, was diagnosed with pneumonia staphylococcal and was treated with Zyvox. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, bone marrow failure, hepatic enzyme increased, multi-organ failure, platelet count decreased, red blood cell count decreased. Zyvox dosage: unknown. During the same period patient was treated with MINOCYCLINE, MEROPEN, PAZUFLOXACIN MESILATE, VANCOMYCIN, FLUCONAZOLE, MICAFUNGIN, AMIKACIN SULPHATE, MAXIPIME. Patient was hospitalized and became disabled. Patient died on 09/16/2005.

Zyvox Side Effects Report #5229719-X
Zyvox side effect was reported by a Consumer or non-health professional from JAPAN on Jan 24, 2007. Male patient, weighting 132.3 lb, was diagnosed with pneumonia bacterial and was treated with Zyvox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, bone marrow failure, liver disorder, multi-organ failure, platelet count decreased, red blood cell count decreased, renal failure acute. Zyvox dosage: unknown. During the same period patient was treated with VANCOMYCIN HYDROCHLORIDE, AZACTAM, TAZOCIN, PAZUFLOXACIN, PENMALIN, MICAFUNGIN, MEROPENEM, NOREPINEPHRINE BITARTRATE. Patient died on 09/30/2005.

Zyvox Side Effects Report #5267723-6
Zyvox side effect was reported by a Consumer or non-health professional from JAPAN on Mar 06, 2007. Male patient, weighting 132.3 lb, was diagnosed with pneumonia bacterial and was treated with Zyvox. After drug was administered, patient experienced the following side effects: liver disorder, multi-organ failure, platelet count decreased, red blood cell count decreased, renal failure acute. Zyvox dosage: unknown. During the same period patient was treated with VANCOMYCIN, AZACTAM, TAZOCIN, PAZUFLOXACIN, PENMALIN, MICAFUNGIN, MEROPENEM, NOREPINEPHRINE BITARTRATE. Patient died on 09/30/2005.


Zyvox Side Effects Report #5243216-7
Zyvox side effect was reported by a Consumer or non-health professional from KOREA, REPUBLIC OF on Feb 13, 2007. Female patient, weighting 142.6 lb, was diagnosed with pneumonia  and was treated with Zyvox. After drug was administered, patient experienced the following side effects: multi-organ failure, septic shock. Zyvox dosage: unknown. During the same period patient was treated with HYDROCORTISONE, PIPERACILLIN, TRANEXAMIC ACID, UNASYN. Patient died on 07/26/2006.

Zyvox Side Effects Report #5900415-6
Zyvox side effect was reported by a Physician from JAPAN on Sept 16, 2008. Female patient, 90 years of age, was diagnosed with infection  and was treated with Zyvox. After drug was administered, patient experienced the following side effects: disseminated intravascular coagulation, multi-organ failure, platelet count decreased. Zyvox dosage: unknown. Patient was hospitalized. Patient died on 09/16/2008.

Zyvox Side Effects Report #5146620-0
Zyvox side effect was reported by a Physician from JAPAN on Oct 19, 2006. Male patient, 78 years of age, weighting 143.3 lb, was diagnosed with infection  and was treated with Zyvox. After drug was administered, patient experienced the following side effects: disseminated intravascular coagulation, multi-organ failure, platelet count decreased. Zyvox dosage: 1200 MG (2 IN 1 D), ORAL. During the same period patient was treated with HABEKACIN. Patient died on 10/08/2006.

Zyvox Side Effects Report #5258101-4
Zyvox side effect was reported by a Physician from JAPAN on Feb 23, 2007. Male patient, weighting 143.3 lb, was diagnosed with infection  and was treated with Zyvox. After drug was administered, patient experienced the following side effects: disseminated intravascular coagulation, multi-organ failure, platelet count decreased. Zyvox dosage: DAILY DOSE:1200MG. During the same period patient was treated with HABEKACIN. Patient died on 10/08/2006.

Zyvox Side Effects Report #5128211-0
Zyvox side effect was reported by a Physician from JAPAN on Oct 04, 2006. Female patient, 79 years of age, weighting 99.21 lb, was diagnosed with enterococcal infection and was treated with Zyvox. After drug was administered, patient experienced the following side effects: liver disorder, multi-organ failure, pancytopenia, renal disorder. Zyvox dosage: 1200 MG (600 MG, 2 IN 1 D), INTRAVENOUS. During the same period patient was treated with VANCOMYCIN, CIPROFLOXACIN HYDROCHLORIDE, CLINDAMYCIN HYDROCHLORIDE, VFEND, MEROPENEM TRIHYDRATE, DIGOXIN, LASIX. Patient died on 11/16/2005.


Zyvox Side Effects Report #5186344-7
Zyvox side effect was reported by a Physician from JAPAN on Nov 29, 2006. Female patient, 79 years of age, weighting 99.21 lb, was diagnosed with enterococcal infection and was treated with Zyvox. After drug was administered, patient experienced the following side effects: liver disorder, multi-organ failure, platelet count decreased, renal disorder, sepsis . Zyvox dosage: 1200 MG (600 MG, 2 IN 1 D), INTRAVENOUS. During the same period patient was treated with VANCOMYCIN, CIPROFLOXACIN HYDROCHLORIDE, CLINDAMYCIN HYDROCHLORIDE, VFEND, MEROPENEM TRIHYDRATE, DIGOXIN, LASIX. Patient died on 11/16/2005.

Zyvox Side Effects Report #4875640-6
Zyvox side effect was reported by a Physician from KOREA, REPUBLIC OF on Dec 26, 2005. Female patient, 64 years of age, weighting 127.9 lb, was diagnosed with enterococcal infection, pathogen resistance and was treated with Zyvox. After drug was administered, patient experienced the following side effects: condition aggravated, multi-organ failure, sepsis . Zyvox dosage: 1200 MG (600 MG, 2 IN 1 D), INTRAVENOUS. During the same period patient was treated with LEVOFLOXACIN, MEROPENEM, FLUCONAZOLE, CYCLOSERINE. Patient died on 12/20/2004.

Zyvox Side Effects Report #4909987-1
Zyvox side effect was reported by a Physician from KOREA, REPUBLIC OF on Jan 26, 2006. Female patient, 64 years of age, weighting 127.9 lb, was diagnosed with enterococcal infection, nosocomial infection and was treated with Zyvox. After drug was administered, patient experienced the following side effects: multi-organ failure, sepsis . Zyvox dosage: 1200 MG (600 MG, 2 IN 1 D), INTRAVENOUS. During the same period patient was treated with LEVOFLOXACIN, MEROPENEM, FLUCONAZOLE, CYCLOSERINE, DOPAMINE. Patient died on 12/20/2004.

Zyvox Side Effects Report #5195841-X
Zyvox side effect was reported by a Consumer or non-health professional from JAPAN on Dec 19, 2006. Female patient, weighting 99.21 lb, was diagnosed with enterococcal infection and was treated with Zyvox. After drug was administered, patient experienced the following side effects: liver disorder, multi-organ failure, platelet count decreased, renal disorder, sepsis . Zyvox dosage: unknown. During the same period patient was treated with VANCOMYCIN, CIPROFLOXACIN HYDROCHLORIDE, CLINDAMYCIN HYDROCHLORIDE, VFEND, MEROPENEM TRIHYDRATE, DIGOSIN, LASIX. Patient died on 11/16/2005.

Zyvox Side Effects Report #5233880-0
Zyvox side effect was reported by a Consumer or non-health professional from KOREA, REPUBLIC OF on Jan 25, 2007. Male patient, weighting 143.3 lb, was diagnosed with enterococcal infection and was treated with Zyvox. After drug was administered, patient experienced the following side effects: multi-organ failure, sepsis . Zyvox dosage: unknown. During the same period patient was treated with MEROPENEM. Patient died on 12/21/2005.


Zyvox Side Effects Report #5273056-4
Zyvox side effect was reported by a Consumer or non-health professional from JAPAN on Mar 12, 2007. Female patient, weighting 99.21 lb, was diagnosed with enterococcal infection and was treated with Zyvox. After drug was administered, patient experienced the following side effects: liver disorder, multi-organ failure, renal disorder, sepsis . Zyvox dosage: unknown. During the same period patient was treated with VANCOMYCIN, CIPROFLOXACIN, CLINDAMYCIN HYDROCHLORIDE, VFEND, MEROPENEM TRIHYDRATE, DIGOSIN, LASIX. Patient died on 11/16/2005.

Zyvox Side Effects Report #5120178-4
Zyvox side effect was reported by a Pharmacist from UNITED STATES on Oct 02, 2006. Male patient, 70 years of age, weighting 158.7 lb, was diagnosed with device related infection and was treated with Zyvox. After drug was administered, patient experienced the following side effects: anaemia, cardiovascular disorder, coagulopathy, hypotension, multi-organ failure, renal disorder, sepsis , thrombocytopenia. Zyvox dosage: 600 MG TWICE DAILY PO. Patient was hospitalized. Patient recovered.

Zyvox Side Effects Report #6138615-5
Zyvox side effect was reported by a Physician from CHINA on Mar 19, 2009. Female patient was diagnosed with catheter related infection and was treated with Zyvox. After drug was administered, patient experienced the following side effects: multi-organ failure. Zyvox dosage: 600 MG, 2X/DAY. During the same period patient was treated with TIENAM, CASPOFUNGIN. Patient died on 09/01/2008.